Cell cycle development.

The Keystone Symposium on the Cell Cycle and Development brought together biologists with an interest in how cell cycle control is integrated into the ontogenetic program of multicellular organisms, and showcased research using a wide variety of systems from both animals and plants. A clear indication from the meeting is that this research is changing the conventional wisdom on both cell cycle control and development.

[1]  J. Massagué,et al.  TGFβ influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b , 2001, Nature Cell Biology.

[2]  Yan Geng,et al.  Cyclin E Ablation in the Mouse , 2003, Cell.

[3]  E. Kondorosi,et al.  Two Classes of the Cdh1-Type Activators of the Anaphase-Promoting Complex in Plants: Novel Functional Domains and Distinct Regulation On-line version contains Web-only data. , 2004, The Plant Cell Online.

[4]  C. Sherr.  The Pezcoller lecture: cancer cell cycles revisited. , 2000, Cancer research.

[5]  G. Dotto,et al.  A dynamic model of keratinocyte stem cell renewal and differentiation: role of the p21WAF1/Cip1 and Notch1 signaling pathways. , 2004, The journal of investigative dermatology. Symposium proceedings.

[6]  B. Dickson,et al.  The Drosophila Tuberous Sclerosis Complex Gene Homologs Restrict Cell Growth and Cell Proliferation , 2001, Cell.

[7]  A. Ferrando,et al.  Requirement for cyclin D3 in lymphocyte development and T cell leukemias. , 2003, Cancer cell.

[8]  P. Kaldis,et al.  Cdk2 Knockout Mice Are Viable , 2003, Current Biology.

[9]  Daniel A. Haber,et al.  Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines , 2001, Nature.

[10]  Hannele Ruohola-Baker,et al.  Notch-Dependent Fizzy-Related/Hec1/Cdh1 Expression Is Required for the Mitotic-to-Endocycle Transition in Drosophila Follicle Cells , 2004, Current Biology.

[11]  D. Prober,et al.  Drosophila myc Regulates Cellular Growth during Development , 1999, Cell.

[12]  H. Ruohola-Baker,et al.  Notch-Delta signaling induces a transition from mitotic cell cycle to endocycle in Drosophila follicle cells. , 2001, Development.

[13]  D. Inzé,et al.  Cell cycle: the key to plant growth control? , 2003, Trends in plant science.

[14]  E. Wieschaus,et al.  A Genetic Link between Morphogenesis and Cell Division during Formation of the Ventral Furrow in Drosophila , 2000, Cell.

[15]  E. Fedorova,et al.  Endoreduplication Mediated by the Anaphase-Promoting Complex Activator CCS52A Is Required for Symbiotic Cell Differentiation in Medicago truncatula Nodules Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.014373. , 2003, The Plant Cell Online.

[16]  Juan Mata,et al.  Tribbles Coordinates Mitosis and Morphogenesis in Drosophila by Regulating String/CDC25 Proteolysis , 2000, Cell.

[17]  G. Dotto,et al.  p21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[18]  W. C. Forrester,et al.  The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation. , 2001, Molecular cell.

[19]  I. Hariharan,et al.  The Drosophila Mst Ortholog, hippo, Restricts Growth and Cell Proliferation and Promotes Apoptosis , 2003, Cell.

[20]  J. Murray,et al.  Altered Cell Cycle Distribution, Hyperplasia, and Inhibited Differentiation in Arabidopsis Caused by the D-Type Cyclin CYCD3 Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.004838. , 2003, The Plant Cell Online.

[21]  D. Rowitch,et al.  Development of mice expressing a single D-type cyclin. , 2002, Genes & development.

[22]  A. Gudkov,et al.  Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence. , 2002, Genes & development.

[23]  B. Edgar,et al.  Rheb promotes cell growth as a component of the insulin/TOR signalling network , 2003, Nature Cell Biology.

[24]  J. Coffman.  Runx transcription factors and the developmental balance between cell proliferation and differentiation , 2003, Cell biology international.

[25]  K. Torii,et al.  Dominant-Negative Receptor Uncovers Redundancy in the Arabidopsis ERECTA Leucine-Rich Repeat Receptor–Like Kinase Signaling Pathway That Regulates Organ Shape Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.010413. , 2003, The Plant Cell Online.

[26]  E. Levine,et al.  Genetic rescue of cell number in a mouse model of microphthalmia: interactions between Chx10 and G1-phase cell cycle regulators , 2003, Development.

[27]  Ping Chen,et al.  Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d , 2003, Nature Cell Biology.

[28]  Freddy Radtke,et al.  Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation , 2001, The EMBO journal.

[29]  B. Edgar,et al.  Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. , 2003, Genes & development.

[30]  Crisanto Gutierrez,et al.  A genome-wide identification of E2F-regulated genes in Arabidopsis. , 2003, The Plant journal : for cell and molecular biology.

[31]  D. Haber,et al.  salvador Promotes Both Cell Cycle Exit and Apoptosis in Drosophila and Is Mutated in Human Cancer Cell Lines , 2002, Cell.

[32]  Walter F. Leise,et al.  Inhibition of the cell cycle is required for convergent extension of the paraxial mesoderm during Xenopus neurulation , 2004, Development.

[33]  M. Justice,et al.  A twist code determines the onset of osteoblast differentiation. , 2004, Developmental cell.

[34]  T. Xu,et al.  Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase. , 1995, Development.

[35]  N. Dyson,et al.  Functional antagonism between E2F family members. , 2001, Genes & development.

[36]  T. Orr-Weaver,et al.  Gene amplification as a developmental strategy: isolation of two developmental amplicons in Drosophila. , 2004, Developmental cell.

[37]  N. Dyson,et al.  Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway. , 2003, Genes & development.

[38]  H. Richardson,et al.  scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila , 2003, The EMBO journal.

[39]  Ryan S. Udan,et al.  Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway , 2003, Nature Cell Biology.

[40]  L. Terracciano,et al.  Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6. , 2000, Science.

[41]  C. Gutiérrez,et al.  Expression and Stability of Arabidopsis CDC6 Are Associated with Endoreplication Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.010329. , 2001, The Plant Cell Online.

[42]  M. Leptin,et al.  Tribbles, a cell-cycle brake that coordinates proliferation and morphogenesis during Drosophila gastrulation , 2000, Current Biology.

[43]  E. Kipreos,et al.  CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing , 2003, Nature.

[44]  Wei Du,et al.  Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E , 2002, Nature.

[45]  Martin Raff,et al.  Differences in the way a mammalian cell and yeast cells coordinate cell growth and cell-cycle progression , 2003, Journal of biology.

[46]  S. Anderson,et al.  Integration of Smad and Forkhead Pathways in the Control of Neuroepithelial and Glioblastoma Cell Proliferation , 2004, Cell.

[47]  P. Pandolfi,et al.  Does the ribosome translate cancer? , 2003, Nature Reviews Cancer.

[48]  Morphogenesis during Xenopus gastrulation requires Wee1-mediated inhibition of cell proliferation , 2004, Development.

[49]  J. S. Britton,et al.  Drosophila's insulin/PI3-kinase pathway coordinates cellular metabolism with nutritional conditions. , 2002, Developmental cell.

[50]  P J Bryant,et al.  The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation. , 1995, Genes & development.