Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development.
暂无分享,去创建一个
U. Landegren | C. Betsholtz | H. Gerhardt | D. Spillmann | G. Bondjers | A. Abramsson | S. Kurup | L. Kjellén | D. Stenzel | M. Busse | Edith Schallmeiner | P. Lindblom | U. Lindahl | Jin-ping Li | J. Ledin | S. Yamada | M. Ringvall | D. Sauvaget
[1] Ulf Landegren,et al. Sensitive protein detection via triple-binder proximity ligation assays , 2007, Nature Methods.
[2] M. Pardue,et al. The Journal of Cell Biology , 2002 .
[3] J. Kreuger,et al. Heparan sulfate in trans potentiates VEGFR-mediated angiogenesis. , 2006, Developmental cell.
[4] D. Spillmann,et al. 3-O-Sulfated Oligosaccharide Structures Are Recognized by Anti-heparan Sulfate Antibody HS4C3* , 2006, Journal of Biological Chemistry.
[5] Christopher J. Robinson,et al. VEGF165-binding Sites within Heparan Sulfate Encompass Two Highly Sulfated Domains and Can Be Liberated by K5 Lyase* , 2006, Journal of Biological Chemistry.
[6] T. Hata,et al. Developmental and regional expression of heparan sulfate sulfotransferase genes in the mouse brain. , 2005, Glycobiology.
[7] J. Esko,et al. Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function , 2005, Development.
[8] N. Perrimon,et al. Developmental cell biology: Heparan sulphate proteoglycans: the sweet side of development , 2005, Nature Reviews Molecular Cell Biology.
[9] J. van den Born,et al. Novel Heparan Sulfate Structures Revealed by Monoclonal Antibodies* , 2005, Journal of Biological Chemistry.
[10] Xinhua Lin,et al. Functions of heparan sulfate proteoglycans in cell signaling during development , 2004, Development.
[11] L. Kjellén,et al. Heparan Sulfate Synthesized by Mouse Embryonic Stem Cells Deficient in NDST1 and NDST2 Is 6-O-Sulfated but Contains No N-Sulfate Groups* , 2004, Journal of Biological Chemistry.
[12] Johan Ledin,et al. Heparan Sulfate Structure in Mice with Genetically Modified Heparan Sulfate Production* , 2004, Journal of Biological Chemistry.
[13] C. Betsholtz. Insight into the physiological functions of PDGF through genetic studies in mice. , 2004, Cytokine & growth factor reviews.
[14] Minoru Takemoto,et al. Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities , 2004, Development.
[15] A. Rapraeger,et al. Syndecans in tumor cell adhesion and signaling , 2004, Reproductive biology and endocrinology : RB&E.
[16] Philippe Soriano,et al. Additive Effects of PDGF Receptor β Signaling Pathways in Vascular Smooth Muscle Cell Development , 2003, PLoS biology.
[17] C. Betsholtz,et al. Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors. , 2003, The Journal of clinical investigation.
[18] U. Landegren,et al. Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall. , 2003, Genes & development.
[19] M. Åbrink,et al. Targeted Disruption of a Murine Glucuronyl C5-epimerase Gene Results in Heparan Sulfate Lacking l-Iduronic Acid and in Neonatal Lethality* , 2003, Journal of Biological Chemistry.
[20] Holger Gerhardt,et al. Endothelial-pericyte interactions in angiogenesis , 2003, Cell and Tissue Research.
[21] K. Alitalo,et al. VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia , 2003, The Journal of cell biology.
[22] H. Hammes,et al. Pericytes and the Pathogenesis of Diabetic Retinopathy , 2005, Diabetes.
[23] J. Esko,et al. Heparan sulfate and development: differential roles of the N-acetylglucosamine N-deacetylase/N-sulfotransferase isozymes. , 2002, Biochimica et biophysica acta.
[24] R. Timpl,et al. Role of heparan sulfate domain organization in endostatin inhibition of endothelial cell function , 2002, The EMBO journal.
[25] J. Esko,et al. Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling. , 2002, Glycobiology.
[26] Holger Gerhardt,et al. Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis. , 2002, Genes & development.
[27] P. Jemth,et al. Biosynthetic Oligosaccharide Libraries for Identification of Protein-binding Heparan Sulfate Motifs , 2002, The Journal of Biological Chemistry.
[28] H. Hammes,et al. Endothelium‐specific platelet‐derived growth factor‐B ablation mimics diabetic retinopathy , 2002, The EMBO journal.
[29] J. Turnbull,et al. Fibroblast Growth Factor Receptors 1 and 2 Interact Differently with Heparin/Heparan Sulfate , 2002, The Journal of Biological Chemistry.
[30] L. Claesson‐Welsh,et al. Heparin Amplifies Platelet-derived Growth Factor (PDGF)- BB-induced PDGF α-Receptor but Not PDGF β-Receptor Tyrosine Phosphorylation in Heparan Sulfate-deficient Cells , 2002, The Journal of Biological Chemistry.
[31] Kenneth M. Yamada,et al. Integrin regulation of growth factor receptors , 2002, Nature Cell Biology.
[32] S. Selleck,et al. Order out of chaos: assembly of ligand binding sites in heparan sulfate. , 2002, Annual review of biochemistry.
[33] B. Ramsahoye. Nearest-neighbor analysis. , 2002, Methods in molecular biology.
[34] J. Gallagher. Heparan sulfate: growth control with a restricted sequence menu. , 2001, The Journal of clinical investigation.
[35] J. Esko,et al. Molecular diversity of heparan sulfate. , 2001, The Journal of clinical investigation.
[36] T. V. van Kuppevelt,et al. Defective Heparan Sulfate Biosynthesis and Neonatal Lethality in Mice LackingN-Deacetylase/N-Sulfotransferase-1* , 2000, The Journal of Biological Chemistry.
[37] A. Woods,et al. Syndecan-4 and integrins: combinatorial signaling in cell adhesion. , 1999, Journal of cell science.
[38] L. Hellman,et al. Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme , 1999, Nature.
[39] C. Betsholtz,et al. Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. , 1999, Development.
[40] U. Hedin,et al. Heparan sulfate proteoglycans mediate a potent inhibitory signal for migration of vascular smooth muscle cells. , 1998, Circulation research.
[41] D. Spillmann,et al. Defining the Interleukin-8-binding Domain of Heparan Sulfate* , 1998, The Journal of Biological Chemistry.
[42] D. Spillmann,et al. Structural Requirement of Heparan Sulfate for Interaction with Herpes Simplex Virus Type 1 Virions and Isolated Glycoprotein C* , 1997, The Journal of Biological Chemistry.
[43] S. Stringer,et al. Specific Binding of the Chemokine Platelet Factor 4 to Heparan Sulfate* , 1997, The Journal of Biological Chemistry.
[44] B R Johansson,et al. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. , 1997, Science.
[45] D. Spillmann,et al. Characterization of Heparin and Heparan Sulfate Domains Binding to the Long Splice Variant of Platelet-derived Growth Factor A Chain* , 1997, The Journal of Biological Chemistry.
[46] G. Bondjers,et al. Alternative splicing determines the binding of platelet-derived growth factor (PDGF-AA) to glycosaminoglycans. , 1996, Biochemistry.
[47] J. Turnbull,et al. Molecular organization of the interferon gamma-binding domain in heparan sulphate. , 1995, The Biochemical journal.
[48] S. Aaronson,et al. A novel mechanism regulating growth factor association with the cell surface: identification of a PDGF retention domain. , 1991, Genes & development.
[49] C. Heldin,et al. Identification of a cell retention signal in the B-chain of platelet-derived growth factor and in the long splice version of the A-chain. , 1991, Cell regulation.
[50] O. Yoshie,et al. A syngeneic monoclonal antibody to murine Meth-A sarcoma (HepSS-1) recognizes heparan sulfate glycosaminoglycan (HS-GAG): cell density and transformation dependent alteration in cell surface HS-GAG defined by HepSS-1. , 1986, Journal of immunology.
[51] M. Höök,et al. N-[3H]Acetyl-labeling, a convenient method for radiolabeling of glycosaminoglycans. , 1982, Analytical biochemistry.
[52] C. He,et al. Nearest neighbor analysis of heparin: identification and quantitation of the products formed by selective depolymerization procedures. , 1976 .