Intensive care unit length of stay: Recent changes and future challenges

ObjectiveTo compare case-mix adjusted intensive care unit (ICU) length of stay for critically ill patients with a variety of medical and surgical diagnoses during a 5-yr interval. DesignNonrandomized cohort study. SettingA total of 42 ICUs at 40 US hospitals during 1988–1990 and 285 ICUs at 161 US hospitals during 1993–1996. PatientsA total of 17,105 consecutive ICU admissions during 1988–1990 and 38,888 consecutive ICU admissions during 1993–1996. Measurements and Main ResultsWe used patient demographic and clinical characteristics to compare observed and predicted ICU length of stay and hospital mortality. Outcomes for patients studied during 1993–1996 were predicted using multivariable models that were developed and cross-validated using the 1988–1990 database. The mean observed hospital length of stay decreased by 3 days (from 14.8 days during 1988–1990 to 11.8 days during 1993–1996), but the mean observed ICU length of stay remained similar (4.70 vs. 4.53 days). After adjusting for patient and institutional differences, the mean predicted 1993–1996 ICU stay was 4.64 days. Thus, the mean-adjusted ICU stay decreased by 0.11 days during this 5-yr interval (T-statistic, 4.35;p < .001). The adjusted mean ICU length of stay was not changed for patients with 49 (75%) of the 65 ICU admission diagnoses. In contrast, the mean observed hospital length of stay was significantly shorter for 47 (72%) of the 65 admission diagnoses, and no ICU admission diagnosis was associated with a longer hospital stay. Aggregate risk-adjusted hospital mortality during 1993–1996 (12.35%) was not significantly different during 1988–1990 (12.27%, p = .54). ConclusionsFor patients admitted to ICUs, the pressures associated with a decrease in hospital length of stay do not seem to have influenced the duration of ICU stay. Because of the high cost of intensive care, reduction in ICU stay may become a target for future cost-cutting efforts.

[1]  M. Niederman,et al.  A "closed" medical intensive care unit (MICU) improves resource utilization when compared with an "open" MICU. , 1998, American journal of respiratory and critical care medicine.

[2]  W. Weaver,et al.  Length of hospital stay after acute myocardial infarction in the Myocardial Infarction Triage and Intervention (MITI) Project registry. , 1996, Journal of the American College of Cardiology.

[3]  S Sauer,et al.  A randomized, controlled trial of protocol-directed versus physician-directed weaning from mechanical ventilation. , 1997, Critical care medicine.

[4]  P. Braveman,et al.  Early discharge and evidence-based practice. Good science and good judgment. , 1997, JAMA.

[5]  W. Knaus,et al.  Evaluation of acute physiology and chronic health evaluation III predictions of hospital mortality in an independent database. , 1998, Critical care medicine.

[6]  E. Keeler,et al.  Quality of care before and after implementation of the DRG-based prospective payment system. A summary of effects. , 1990, JAMA.

[7]  E. Draper,et al.  Improving intensive care unit discharge decisions: Supplementing physician judgment with predictions of next day risk for life support , 1994, Critical care medicine.

[8]  L. Casalino,et al.  The growth of medical groups paid through capitation in California. , 1995, The New England journal of medicine.

[9]  T. Bodenheimer,et al.  Capitation or decapitation: keeping your head in changing times. , 1996, JAMA.

[10]  R. Viggiano,et al.  Outcomes of patients admitted to a chronic ventilator-dependent unit in an acute-care hospital. , 1992, Mayo Clinic proceedings.

[11]  L. Goldman,et al.  Cost-effectiveness of a coronary care unit versus an intermediate care unit for emergency department patients with chest pain. , 1996, Circulation.

[12]  D. Bates,et al.  Coronary Angiography and Angioplasty after Acute Myocardial Infarction , 1997, Annals of Internal Medicine.

[13]  D Draper,et al.  Interpreting hospital mortality data. The role of clinical risk adjustment. , 1988, JAMA.

[14]  M. Simoons,et al.  A clinical trial comparing primary coronary angioplasty with tissue plasminogen activator for acute myocardial infarction. , 1997, The New England journal of medicine.

[15]  S. Kelley,et al.  Immediate Tracheal Extubation After Liver Transplantation: Experience of Two Transplant Centers , 1997, Anesthesia and analgesia.

[16]  W. Knaus,et al.  The APACHE III prognostic system. Risk prediction of hospital mortality for critically ill hospitalized adults. , 1991, Chest.

[17]  E. Draper,et al.  Improving intensive care: Observations based on organizational case studies in nine intensive care units A prospective, multicenter study , 1993, Critical care medicine.

[18]  J. Findlay Current Management of Aneurysmal Subarachnoid Hemorrhage Guidelines from the Canadian Neurosurgical Society , 1997, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[19]  J. Rapoport,et al.  Economic implications of the timing of do-not-resuscitate orders for ICU patients. , 1997, New horizons.

[20]  D Elmqvist Myasthenia Gravis , 1975, The Lancet.

[21]  W. Knaus,et al.  Variations in Mortality and Length of Stay in Intensive Care Units , 1993, Annals of Internal Medicine.

[22]  A. Ellrodt,et al.  Measuring and Improving Physician Compliance with Clinical Practice Guidelines: A Controlled Interventional Trial , 1995, Annals of Internal Medicine.

[23]  S. Lemeshow,et al.  Resource utilization among intensive care patients. Managed care vs traditional insurance. , 1992, Archives of internal medicine.

[24]  D Draper,et al.  Comparing outcomes of care before and after implementation of the DRG-based prospective payment system. , 1990, JAMA.

[25]  T. Bleck Medical management of subarachnoid hemorrhage. , 1997, New horizons.

[26]  U. Ruttimann,et al.  Variability in duration of stay in pediatric intensive care units: a multiinstitutional study. , 1996, The Journal of pediatrics.

[27]  Findlay Jm Current management of aneurysmal subarachnoid hemorrhage guidelines from the Canadian Neurosurgical Society. , 1997 .

[28]  R H Brook,et al.  Explaining variations in hospital death rates. Randomness, severity of illness, quality of care. , 1990, JAMA.

[29]  P. Schmitz,et al.  A randomized trial comparing intravenous immune globulin and plasma exchange in Guillain-Barré syndrome. Dutch Guillain-Barré Study Group. , 1992, The New England journal of medicine.

[30]  R. L. Rosen,et al.  The noninvasive respiratory care unit. Patterns of use and financial implications. , 1991, Chest.

[31]  P. Collier,et al.  Do clinical pathways for major vascular surgery improve outcomes and reduce cost? , 1997, Journal of vascular surgery.

[32]  H. Krumholz,et al.  Improving the quality of care for Medicare patients with acute myocardial infarction: results from the Cooperative Cardiovascular Project. , 1998, JAMA.

[33]  D. Bates,et al.  The Costs of Adverse Drug Events in Hospitalized Patients , 1997 .

[34]  W. Knaus,et al.  Reliability of a measure of severity of illness: acute physiology of chronic health evaluation--II. , 1992, Journal of clinical epidemiology.

[35]  D. Classen,et al.  Adverse drug events in hospitalized patients. Excess length of stay, extra costs, and attributable mortality. , 1997, JAMA.

[36]  C. Peniston,et al.  Early Tracheal Extubation after Coronary Artery Bypass Graft Surgery Reduces Costs and Improves Resource Use: A Prospective, Randomized, Controlled Trial , 1996, Anesthesiology.

[37]  Marni,et al.  Discharging patients earlier from Winnipeg hospitals: does it adversely affect quality of care? , 1995, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

[38]  E. Topol,et al.  Limitations of thrombolytic therapy for acute myocardial infarction complicated by congestive heart failure and cardiogenic shock. , 1991, Journal of the American College of Cardiology.

[39]  N. Halpern,et al.  Federal and nationwide intensive care units and healthcare costs: 1986–1992 , 1994, Critical care medicine.

[40]  T. Clemmer,et al.  Descriptive analysis of critical care units in the United States , 1992, Critical care medicine.

[41]  E F Haponik,et al.  Effect on the duration of mechanical ventilation of identifying patients capable of breathing spontaneously. , 1996, The New England journal of medicine.

[42]  L. Hydo,et al.  Utility of illness severity scoring for prediction of prolonged surgical critical care. , 1996, The Journal of trauma.

[43]  C. Sirio,et al.  Cleveland Health Quality Choice (CHQC)--an ongoing collaborative, community-based outcomes assessment program. , 1994, New horizons.

[44]  William C. Cockerham Physicians , 2001, BMJ : British Medical Journal.

[45]  R. Brook,et al.  The early effect of Medicare's prospective payment system on the use of medical intensive care services in three community hospitals. , 1988, JAMA.

[46]  R. Stern,et al.  A comparison of length of stay and costs for health maintenance organization and fee-for-service patients. , 1989, Archives of internal medicine.

[47]  R. Bone,et al.  Analysis of indications for early discharge from the intensive care unit. Clinical efficacy assessment project: American College of Physicians. , 1993, Chest.

[48]  S M Shortell,et al.  The Performance of Intensive Care Units: Does Good Management Make a Difference? , 1994, Medical care.

[49]  S. Lemeshow,et al.  Resource use implications of do not resuscitate orders for intensive care unit patients. , 1996, American journal of respiratory and critical care medicine.

[50]  M. Morasch,et al.  Selective use of the intensive care unit following carotid endarterectomy , 1995, Annals of vascular surgery.

[51]  P. Bach,et al.  Outcomes and resource utilization for patients with prolonged critical illness managed by university-based or community-based subspecialists. , 1998, American journal of respiratory and critical care medicine.

[52]  W. Knaus,et al.  The use of APACHE III to evaluate ICU length of stay, resource use, and mortality after coronary artery by-pass surgery. , 1995, The Journal of cardiovascular surgery.

[53]  B. W. Nicholson,et al.  Length of stay in the intensive care unit. Effects of practice guidelines and feedback. , 1990, JAMA.

[54]  J. Bederson,et al.  Hypertensive, hypervolemic, hemodilutional therapy for aneurysmal subarachnoid hemorrhage. Is it efficacious? Yes. , 1996, Critical care clinics.

[55]  Sankey V. Williams,et al.  Mortality and complications associated with laparoscopic cholecystectomy. A meta-analysis. , 1996, Annals of surgery.

[56]  L Goldman,et al.  A Critical Pathway for Management of Patients with Acute Chest Pain Who Are at Low Risk for Myocardial Ischemia: Recommendations and Potential Impact , 1997, Annals of Internal Medicine.

[57]  R. Oye,et al.  Patterns of resource consumption in medical intensive care. , 1991, Chest.

[58]  P. Schmitz,et al.  A randomized trial comparing intravenous immunoglobulin and plasma exchange in Guillain-Barré syndrome. , 1994, Transfusion science.

[59]  L. Kraiss,et al.  Short-stay carotid endarterectomy is safe and cost-effective. , 1995, American journal of surgery.

[60]  G. Cooper,et al.  Severity-adjusted mortality and length of stay in teaching and nonteaching hospitals. Results of a regional study. , 1998, JAMA.

[61]  S. Katz,et al.  Selective use of the intensive care unit after nonaortic arterial surgery. , 1996, Journal of vascular surgery.

[62]  S G Pauker,et al.  Variations in length of stay and outcomes for six medical and surgical conditions in Massachusetts and California. , 1991, JAMA.

[63]  J. Lave,et al.  The effect of managed care on ICU length of stay: implications for medicare. , 1996, JAMA.

[64]  F. Cerra,et al.  Descriptive analysis of critical care units in the United States: Patient characteristics and intensive care unit utilization , 1993, Critical care medicine.

[65]  S. Chevret,et al.  Iatrogenic complications in adult intensive care units: A prospective two‐center study , 1993, Critical care medicine.

[66]  H. Rubash,et al.  Early inpatient rehabilitation after elective hip and knee arthroplasty. , 1998, JAMA.

[67]  R. Engelman Mechanisms to reduce hospital stays. , 1996, The Annals of thoracic surgery.

[68]  J. Oropello,et al.  Hypertensive, hypervolemic, hemodilutional therapy for aneurysmal subarachnoid hemorrhage. Is it efficacious? No. , 1996, Critical care clinics.

[69]  R. Blancas,et al.  Early vs conventional extubation after cardiac surgery with cardiopulmonary bypass. , 1997, Chest.

[70]  P. Mcaleese,et al.  The Effect of Complications on Length of Stay , 1994, Annals of surgery.

[71]  C. Stocking,et al.  Effects of organizational change in the medical intensive care unit of a teaching hospital: a comparison of 'open' and 'closed' formats. , 1996, JAMA.

[72]  A. Ellrodt,et al.  Prospective evaluation of a clinical guideline recommending hospital length of stay in upper gastrointestinal tract hemorrhage. , 1997, JAMA.

[73]  David J. Dries,et al.  GATEKEEPING IN THE INTENSIVE CARE UNIT , 1998 .

[74]  Robert M. Nelson,et al.  Consensus Statement on the Triage of Critically III Patients , 1994 .

[75]  W. Schwartz,et al.  Hospital cost containment in the 1980s. Hard lessons learned and prospects for the 1990s. , 1991, The New England journal of medicine.

[76]  Russell L. Stogsdill,et al.  A regional intervention to improve the hospital mortality associated with coronary artery bypass graft surgery. The Northern New England Cardiovascular Disease Study Group. , 1996, JAMA.

[77]  M. Boyer Women and children first , 1993, Nature.

[78]  B. Kavanagh,et al.  Utilization of intensive care unit days in a Canadian medical-surgical intensive care unit. , 1999, Critical care medicine.

[79]  Lagoe Rj A community-based analysis of regional differences in hospital stays by diagnosis related group. , 1986 .

[80]  David W. Bates,et al.  The costs of adverse drug events in hospitalized patients. Adverse Drug Events Prevention Study Group , 1997 .

[81]  A. Ellrodt,et al.  Practice Guidelines and Reminders to Reduce Duration of Hospital Stay for Patients with Chest Pain: An Interventional Trial , 1994, Annals of Internal Medicine.

[82]  W. Knaus,et al.  Neurological intensive care admissions: identifying candidates for intermediate care and the services they receive. , 1998, Neurosurgery.

[83]  B. Make,et al.  Mechanical ventilation beyond the intensive care unit. Report of a consensus conference of the American College of Chest Physicians. , 1998, Chest.

[84]  A. Ellrodt,et al.  Reducing Lengths of Stay in the Coronary Care Unit With a Practice Guideline for Patients With Congestive Heart Failure Insights From a Controlled Clinical Trial , 1994, Medical care.