Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1
暂无分享,去创建一个
A. Klein-Szanto | A. Giordano | L. Bagella | I. Marchesi | F. Rizzolio | Andres J Klein-Szanto | M. Castronovo | I. Caligiuri | C. Lucchetti | M. Caputo
[1] Antonio Rosato,et al. A Pin1/mutant p53 axis promotes aggressiveness in breast cancer. , 2011, Cancer cell.
[2] Young Sun,et al. p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosis , 2010, Oncogene.
[3] F. Dick,et al. An Overlapping Kinase and Phosphatase Docking Site Regulates Activity of the Retinoblastoma Protein , 2010, Nature Structural &Molecular Biology.
[4] M. Prados,et al. Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts. , 2010, Cancer research.
[5] Jeffrey G. Pelton,et al. Phosphorylation-induced Conformational Changes in the Retinoblastoma Protein Inhibit E2F Transactivation Domain Binding* , 2010, The Journal of Biological Chemistry.
[6] A. Giordano,et al. CDK inhibitors: from the bench to clinical trials. , 2010, Current drug targets.
[7] A. Ryo,et al. Pin1 Catalyzes Conformational Changes of Thr-187 in p27Kip1 and Mediates Its Stability through a Polyubiquitination Process* , 2009, The Journal of Biological Chemistry.
[8] M. Pellecchia,et al. Discovery and Binding Studies on a Series of Novel Pin1 Ligands , 2009, Chemical biology & drug design.
[9] I. Raška,et al. Inhibition of the peptidyl-prolyl-isomerase Pin1 enhances the responses of acute myeloid leukemia cells to retinoic acid via stabilization of RARalpha and PML-RARalpha. , 2009, Cancer research.
[10] W. Hahn,et al. SV40 small T antigen and PP2A phosphatase in cell transformation , 2008, Cancer and Metastasis Reviews.
[11] C. Tribioli,et al. Highly Conserved Non-Coding Sequences and the 18q Critical Region for Short Stature: A Common Mechanism of Disease? , 2008, PloS one.
[12] Yuliang Wu,et al. Detecting protein–protein interactions by far western blotting , 2007, Nature Protocols.
[13] W. Gu,et al. Non-transcriptional control of DNA replication by c-Myc , 2007, Nature.
[14] M. Mumby. PP2A: Unveiling a Reluctant Tumor Suppressor , 2007, Cell.
[15] M. Bowman,et al. Structural basis for high-affinity peptide inhibition of human Pin1. , 2007, ACS chemical biology.
[16] A. Giordano,et al. A small molecule based on the pRb2/p130 spacer domain leads to inhibition of cdk2 activity, cell cycle arrest and tumor growth reduction in vivo , 2007, Oncogene.
[17] A. Giordano,et al. Interaction of PP2A catalytic subunit with Rb2/p130 is required for all‐trans retinoic acid suppression of ovarian carcinoma cell growth , 2006, Journal of cellular physiology.
[18] Akira Yamaguchi,et al. Stable Suppression of Tumorigenicity by Pin1-Targeted RNA Interference in Prostate Cancer , 2005, Clinical Cancer Research.
[19] Anthony Scime,et al. Pocket Protein Complexes Are Recruited to Distinct Targets in Quiescent and Proliferating Cells , 2005, Molecular and Cellular Biology.
[20] J. Sowadski,et al. Prevalent overexpression of prolyl isomerase Pin1 in human cancers. , 2004, The American journal of pathology.
[21] A. Means,et al. Pin1 regulates the timing of mammalian primordial germ cell proliferation , 2003, Development.
[22] Sam W. Lee,et al. PIN1 Is an E2F Target Gene Essential for Neu/Ras-Induced Transformation of Mammary Epithelial Cells , 2002, Molecular and Cellular Biology.
[23] S. Rane,et al. Germ Line Transmission of the Cdk4R24C Mutation Facilitates Tumorigenesis and Escape from Cellular Senescence , 2002, Molecular and Cellular Biology.
[24] T. Jacks,et al. Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. , 2000, Genes & development.
[25] J. Herman,et al. In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[26] P. Davies,et al. The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein , 1999, Nature.
[27] L. Leffet,et al. Analysis of site-specific phosphorylation of the retinoblastoma protein during cell cycle progression. , 1999, Experimental Cell Research.
[28] G. Fischer,et al. Selective inactivation of parvulin-like peptidyl-prolyl cis/trans isomerases by juglone. , 1998, Biochemistry.
[29] E. Harlow,et al. Monoclonal antibodies specific for underphosphorylated retinoblastoma protein identify a cell cycle regulated phosphorylation site targeted by CDKs , 1997, Oncogene.
[30] T. Hunter,et al. A human peptidyl–prolyl isomerase essential for regulation of mitosis , 1996, Nature.
[31] C Roskelley,et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[32] Chin-Lee Wu,et al. Copyright � 1995, American Society for Microbiology In Vivo Association of E2F and DP Family Proteins , 1995 .
[33] Sushovan Guha,et al. The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest , 1994, Cell.
[34] J. Bartek,et al. Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining. , 1994, Cancer research.
[35] S. van den Heuvel,et al. Distinct roles for cyclin-dependent kinases in cell cycle control. , 1993, Science.
[36] D. Livingston,et al. Specific enzymatic dephosphorylation of the retinoblastoma protein , 1993, Molecular and cellular biology.
[37] A. Giordano,et al. RB gene family: Genome‐wide ChIP approaches could open undiscovered roads , 2010, Journal of cellular biochemistry.
[38] A. Giordano,et al. Growth control by the retinoblastoma gene family. , 2003, Methods in molecular biology.
[39] Qiang Yu,et al. IGF‐1 induces Pin1 expression in promoting cell cycle S‐phase entry , 2002, Journal of cellular biochemistry.