Implantation site dependent differences for tracheal regeneration with iPS cells

Maximum diameter of teratoma formation in tracheal area Maximum diameter of teratoma formation in abdominal area Implantation site dependent differences for tracheal regeneration with iPS cells Mitsuyoshi Imaizumi, MD1; Yukio Nomoto, MD1; Takashi Sugino, MD2; Yuka Sato, PhD3; Koichi Omori, MD1 Department of 1Otolaryngology, 2Basic Pathology and 3Microbiology, Fukushima Medical University School of Medicine, Fukushima, Japan

[1]  T. Sugino,et al.  Potential of Induced Pluripotent Stem Cells for the Regeneration of the Tracheal Wall , 2010, The Annals of otology, rhinology, and laryngology.

[2]  T. Nagayasu,et al.  Expression of Keratinocyte Growth Factor and Its Receptor in Rat Tracheal Cartilage: Possible Involvement in Wound Healing of the Damaged Cartilage , 2010, Acta histochemica et cytochemica.

[3]  Hideyuki Okano,et al.  Variation in the safety of induced pluripotent stem cell lines , 2009, Nature Biotechnology.

[4]  T. Ichisaka,et al.  GENERATION OF GERMLINECOMPETENT INDUCED PLURIPOTENT STEM CELLS , 2007 .

[5]  S. Yamanaka,et al.  Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors , 2006, Cell.

[6]  Tatsuo Nakamura,et al.  Regenerative Medicine of the Trachea: The First Human Case , 2005, The Annals of otology, rhinology, and laryngology.

[7]  T. Toba,et al.  Artificial Trachea and Long Term follow-up in Carinal Reconstruction in Dogs , 2000, The International journal of artificial organs.

[8]  K. Guan,et al.  Embryonic stem cell-derived chondrogenic differentiation in vitro: activation by BMP-2 and BMP-4 , 2000, Mechanisms of Development.

[9]  R. Cotton.  Management of subglottic stenosis. , 2000, Otolaryngologic clinics of North America.

[10]  A M Mackay,et al.  Chondrogenic differentiation of cultured human mesenchymal stem cells from marrow. , 1998, Tissue engineering.

[11]  V. Consiglio,et al.  The use of patient's own auricular cartilage to repair deficiency of the tracheal wall. , 1961, The Journal of thoracic and cardiovascular surgery.