Respiratory viral infections among hospitalized adults: experience of a single tertiary healthcare hospital

Following the 2009 H1N1 pandemic, there have been a large number of studies focusing on the epidemiology and outcomes of influenza A infection; however, there have been fewer studies focused on other respiratory viral infections.

[1]  P. Palange,et al.  From the authors , 2007, European Respiratory Journal.

[2]  M. Boeckh,et al.  Community-acquired respiratory syncytial virus and parainfluenza virus infections after hematopoietic stem cell transplantation: the Fred Hutchinson Cancer Research Center experience. , 2001, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

[3]  Stefan Gravenstein,et al.  Influenza estacional en adultos y niños—Diagnóstico, tratamiento, quimioprofilaxis y control de brotes institucionales: Guías de práctica clínica de la Sociedad de Enfermedades Infecciosas de Estados Unidos de América , 2009, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[4]  S. Johnston,et al.  Experimental rhinovirus infection as a human model of chronic obstructive pulmonary disease exacerbation. , 2011, American journal of respiratory and critical care medicine.

[5]  S. M. Raboni,et al.  Human metapneumovirus infection in hematopoietic stem cell transplant recipients , 2010, Transplant infectious disease : an official journal of the Transplantation Society.

[6]  L. Simonsen,et al.  The impact of influenza epidemics on mortality: introducing a severity index. , 1997, American journal of public health.

[7]  Joan Wilson,et al.  Respiratory viral infections in adults with and without chronic obstructive pulmonary disease. , 2000, American journal of respiratory and critical care medicine.

[8]  B. Griffith,et al.  Influenza Virus Infection in Adult Solid Organ Transplant Recipients , 2002, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[9]  Robert Schechter,et al.  Factors associated with death or hospitalization due to pandemic 2009 influenza A(H1N1) infection in California. , 2009, JAMA.

[10]  F. Hayden,et al.  Picornavirus infections in children diagnosed by RT‐PCR during longitudinal surveillance with weekly sampling: Association with symptomatic illness and effect of season , 2006, Journal of medical virology.

[11]  J. Englund,et al.  Respiratory syncytial virus upper respiratory tract illnesses in adult blood and marrow transplant recipients: combination therapy with aerosolized ribavirin and intravenous immunoglobulin , 2000, Bone Marrow Transplantation.

[12]  Stephen T Holgate,et al.  Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort study , 2002, The Lancet.

[13]  J. Raboud,et al.  Antiviral therapy and outcomes of influenza requiring hospitalization in Ontario, Canada. , 2007, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[14]  A. Osterhaus,et al.  Human metapneumovirus in a haematopoietic stem cell transplant recipient with fatal lower respiratory tract disease , 2003, Bone Marrow Transplantation.

[15]  J. Pachón,et al.  Timing of oseltamivir administration and outcomes in hospitalized adults with pandemic 2009 influenza A(H1N1) virus infection. , 2011, Chest.

[16]  W. Schaffner,et al.  Description of antiviral treatment among adults hospitalized with influenza before and during the 2009 pandemic: United States, 2005-2009. , 2011, The Journal of infectious diseases.

[17]  S. Johnston,et al.  How Viral Infections Cause Exacerbation of Airway Diseases , 2006, Chest.

[18]  S. Ishizuka,et al.  Effects of rhinovirus infection on the adherence of Streptococcus pneumoniae to cultured human airway epithelial cells. , 2003, The Journal of infectious diseases.

[19]  C. Glaser,et al.  Rhinovirus Outbreak in a Long Term Care Facility for Elderly Persons Associated with Unusually High Mortality , 2005, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[20]  T. Lash,et al.  Obesity as a risk factor for severe influenza-like illness , 2013, Influenza and other respiratory viruses.

[21]  Weizhong Yang,et al.  Risk factors for severe illness with 2009 pandemic influenza A (H1N1) virus infection in China. , 2011, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[22]  I. Bonmarin,et al.  Severe hospitalised 2009 pandemic influenza A(H1N1) cases in France, 1 July-15 November 2009. , 2010, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.

[23]  J. Crowe,et al.  A prospective study comparing human metapneumovirus with other respiratory viruses in adults with hematologic malignancies and respiratory tract infections. , 2005, The Journal of infectious diseases.

[24]  Keiji Fukuda,et al.  Mortality associated with influenza and respiratory syncytial virus in the United States. , 2003, JAMA.

[25]  K. Sepkowitz,et al.  Respiratory syncytial virus infection following hematopoietic stem cell transplantation , 2002, Bone Marrow Transplantation.

[26]  R. Vainionpää,et al.  Parainfluenza virus type 3 infections in a hematology unit , 2001, Bone Marrow Transplantation.

[27]  M. Rozenberg-Arska,et al.  Polymerase Chain Reaction Is More Sensitive than Viral Culture and Antigen Testing for the Detection of Respiratory Viruses in Adults with Hematological Cancer and Pneumonia , 2002, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[28]  D. Hui,et al.  High morbidity and mortality in adults hospitalized for respiratory syncytial virus infections. , 2013, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[29]  J. Sung,et al.  Viral Loads and Duration of Viral Shedding in Adult Patients Hospitalized with Influenza , 2009, The Journal of infectious diseases.

[30]  T. Uyeki,et al.  Influenza estacional en adultos y niños—Diagnóstico, tratamiento, quimioprofilaxis y control de brotes institucionales: Guías de práctica clínica de la Sociedad de Enfermedades Infecciosas de Estados Unidos de América , 2009, Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America.

[31]  A. Ramírez-Venegas,et al.  Clinical characteristics and outcomes of influenza and other influenza-like illnesses in Mexico City , 2013, International Journal of Infectious Diseases.

[32]  K. Ungchusak,et al.  Severe Human Influenza Infections in Thailand: Oseltamivir Treatment and Risk Factors for Fatal Outcome , 2009, PloS one.

[33]  P. Shears,et al.  Dual Infection of Infants by Human Metapneumovirus and Human Respiratory Syncytial Virus Is Strongly Associated with Severe Bronchiolitis , 2005, The Journal of infectious diseases.

[34]  G. Lyon,et al.  Outcomes from pandemic influenza A H1N1 infection in recipients of solid-organ transplants: a multicentre cohort study. , 2010, The Lancet. Infectious diseases.

[35]  G. Vernet,et al.  Respiratory virus infections. , 1965, Lancet.

[36]  R. Couch,et al.  Rhinovirus infections in myelosuppressed adult blood and marrow transplant recipients. , 1999, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[37]  T. Welte,et al.  Community-Acquired Respiratory Viral Infections in Lung Transplant Recipients: A Single Season Cohort Study , 2009, Transplantation.

[38]  L. Bakaletz,et al.  Viral potentiation of bacterial superinfection of the respiratory tract. , 1995, Trends in microbiology.

[39]  Derick R. Peterson,et al.  Human metapneumovirus infections in adults: another piece of the puzzle. , 2008, Archives of internal medicine.

[40]  L. Gubareva,et al.  Antiviral agents for the treatment and chemoprophylaxis of influenza --- recommendations of the Advisory Committee on Immunization Practices (ACIP). , 2011, MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports.

[41]  Keiji Fukuda,et al.  Influenza-associated hospitalizations in the United States. , 2004, JAMA.

[42]  K. Monroe,et al.  Impact of the rapid diagnosis of influenza on physician decision-making and patient management in the pediatric emergency department: results of a randomized, prospective, controlled trial. , 2003, Pediatrics.

[43]  D. Greenberg,et al.  Comparison of Human Metapneumovirus, Respiratory Syncytial Virus and Influenza A Virus Lower Respiratory Tract Infections in Hospitalized Young Children , 2006, The Pediatric infectious disease journal.

[44]  J. R. Pérez Padilla,et al.  Reducing Occurrence and Severity of Pneumonia Due to Pandemic H1N1 2009 by Early Oseltamivir Administration: A Retrospective Study in Mexico , 2011, PloS one.

[45]  D. Murdoch,et al.  Incidence and characteristics of viral community-acquired pneumonia in adults , 2007, Thorax.

[46]  M. Boeckh,et al.  Community Respiratory Virus Infections in Immunocompromised Patients: Hematopoietic Stem Cell and Solid Organ Transplant Recipients, and Individuals with Human Immunodeficiency Virus Infection , 2007, Seminars in respiratory and critical care medicine.

[47]  Robert F. Benson,et al.  Two Outbreaks of Severe Respiratory Disease in Nursing Homes Associated with Rhinovirus , 2006, Journal of the American Geriatrics Society.

[48]  K. Edwards,et al.  Rates of hospitalizations for respiratory syncytial virus, human metapneumovirus, and influenza virus in older adults. , 2012, The Journal of infectious diseases.

[49]  Robert Schechter,et al.  Treatment with neuraminidase inhibitors for critically ill patients with influenza A (H1N1)pdm09. , 2012, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[50]  M. Boeckh,et al.  Brief Communication: Fatal Human Metapneumovirus Infection in Stem-Cell Transplant Recipients , 2006, Annals of Internal Medicine.

[51]  F. Hayden,et al.  Rhinovirus Infections in Hematopoietic Stem Cell Transplant Recipients with Pneumonia , 2003, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[52]  Lyn Finelli,et al.  Hospitalized patients with 2009 H1N1 influenza in the United States, April-June 2009. , 2009, The New England journal of medicine.

[53]  A. Caliendo,et al.  Severity of Human Rhinovirus Infection in Immunocompromised Adults Is Similar to That of 2009 H1N1 Influenza , 2011, Journal of Clinical Microbiology.

[54]  J. Sung,et al.  Outcomes of adults hospitalised with severe influenza , 2010, Thorax.

[55]  S. O'Riordan,et al.  Risk factors and outcomes among children admitted to hospital with pandemic H1N1 influenza , 2010, Canadian Medical Association Journal.

[56]  E. Claas,et al.  Improved Diagnosis of the Etiology of Community-Acquired Pneumonia with Real-Time Polymerase Chain Reaction , 2005, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[57]  C. Litwin,et al.  Seasonality and prevalence of respiratory pathogens detected by multiplex PCR at a tertiary care medical center , 2013, Archives of Virology.

[58]  E. Walsh,et al.  Respiratory Syncytial Virus Infection in Adults , 2011, Seminars in respiratory and critical care medicine.

[59]  A. Armaganidis,et al.  Viral epidemiology of acute exacerbations of chronic obstructive pulmonary disease , 2011, Pulmonary Pharmacology & Therapeutics.

[60]  J. Fox,et al.  Viral Infection in Adults Hospitalized With Community-Acquired Pneumonia , 2008, Chest.

[61]  F Y Aoki,et al.  Early administration of oral oseltamivir increases the benefits of influenza treatment. , 2003, The Journal of antimicrobial chemotherapy.