论文信息 - Lenalidomide downregulates ACE2 protein abundance to alleviate infection by SARS-CoV-2 spike protein conditioned pseudoviruses - 字舞流文

Lenalidomide downregulates ACE2 protein abundance to alleviate infection by SARS-CoV-2 spike protein conditioned pseudoviruses

G. Jiang | L. Wong | Pengda Liu | Ying Wang | Siyuan Su | Zhichuan Zhu | Jianfeng Chen

[1] Qiang Zhou,et al. AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells , 2021, Cell Research.

[2] N. Grandvaux,et al. ACE2: Evidence of role as entry receptor for SARS-CoV-2 and implications in comorbidities , 2020, eLife.

[3] P. Thistlethwaite,et al. MDM2-Mediated Ubiquitination of Angiotensin-Converting Enzyme 2 Contributes to the Development of Pulmonary Arterial Hypertension , 2020, Circulation.

[4] H. Nakaya,et al. ACE2 Expression is Increased in the Lungs of Patients with Comorbidities Associated with Severe COVID-19 , 2020, The Journal of infectious diseases.

[5] S. Carr,et al. Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS , 2015, Nature.