Oral White Sponge Nevus: An Exceptional Differential Diagnosis in Childhood

White sponge nevus is an autosomal dominant skin disorder characterized by white, irregular, diffuse plaques mainly affecting the oral mucosa. Histological findings of white sponge nevus are characteristic but not pathognomonic. We report a case of an oral white sponge nevus in a 6-year-old girl, which poses a problem in differential diagnosis with oral candidiasis. No treatment was performed because of the benign and asymptomatic nature of the lesions.

[1]  M. Sobhan,et al.  White Sponge Nevus: Report of a Case and Review of the Literature. , 2017, Acta medica Iranica.

[2]  D. Nandini,et al.  White sponge nevus: Report of three cases in a single family , 2016, Journal of oral and maxillofacial pathology : JOMFP.

[3]  Q. Li,et al.  Mutational analysis in familial and sporadic patients with white sponge naevus , 2011, The British journal of dermatology.

[4]  L. R. Azevedo,et al.  Orthodontic therapy in a patient with white sponge nevus. , 2004, American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics.

[5]  T. Komori,et al.  Constitutional mutation of keratin 13 gene in familial white sponge nevus. , 2003, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[6]  G. Melino,et al.  A glutamine insertion in the 1A alpha helical domain of the keratin 4 gene in a familial case of white sponge nevus. , 2000, The Journal of investigative dermatology.

[7]  R. Plezia,et al.  Oral squamous-cell carcinoma within a white-sponge nevus. , 1978, The Journal of dermatologic surgery and oncology.

[8]  J. T. Pilcher,et al.  Diseases of the Skin , 1903, The Indian Medical Gazette.

[9]  W. Hager,et al.  and s , 2019, Shallow Water Hydraulics.

[10]  W. Marsden I and J , 2012 .

[11]  J. Hupp Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. Parting thoughts. , 2011, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[12]  T. Saraswathi Shafer′s textbook of oral pathology , 2009, Journal of Oral and Maxillofacial Pathology.