Microwave-assisted extractions of active ingredients from plants.

Microwave-assisted extraction (MAE) is widely employed in the analysis and the extraction of active compounds from plants. This review summarizes the research done during the last decade on the MAE of active ingredients from plants. Advances and modifications to improve the performance of MAE are presented and discussed in detail. Modified MAE such as vacuum microwave-assisted extraction (VMAE), nitrogen-protected microwave-assisted extraction (NPMAE), ultrasonic microwave-assisted extraction (UMAE), dynamic microwave-assisted extraction (DMAE) and other advancements in MAE are also detailed in this article. In addition, the microwave extraction procedures and the important parameters influencing its performance are also included, together with the advantages and the drawbacks of each MAE techniques.

[1]  X. Pan,et al.  Microwave-assisted extraction of tanshinones from Salvia miltiorrhiza bunge with analysis by high-performance liquid chromatography. , 2001, Journal of chromatography. A.

[2]  J. Kwon,et al.  Application of the microwave-assisted process (MAP ) to the fast extraction of ginseng saponins , 2003 .

[3]  P. Bermejo-Barrera,et al.  Microwave assisted extraction of iodine and bromine from edible seaweed for inductively coupled plasma-mass spectrometry determination. , 2009, Talanta.

[4]  J. L. Willett,et al.  Microwave-assisted extraction of phenolics from bean (Phaseolus vulgaris L.) , 2010 .

[5]  M. Xie,et al.  Microwave-assisted extraction used for the isolation of total triterpenoid saponins from Ganoderma atrum , 2007 .

[6]  Parameswarakumar Mallikarjunan,et al.  Microwave-assisted extraction of phenolic antioxidant compounds from peanut skins , 2010 .

[7]  Xiao-hua Xiao,et al.  Evaluation of vacuum microwave-assisted extraction technique for the extraction of antioxidants from plant samples. , 2009, Journal of chromatography. A.

[8]  Alejandro Cifuentes,et al.  Supercritical fluid extraction: Recent advances and applications. , 2010, Journal of chromatography. A.

[9]  Chunzhao Liu,et al.  Dynamic microwave-assisted extraction of flavonoids from Saussurea medusa Maxim cultured cells , 2006 .

[10]  Y. Zu,et al.  Optimization of microwave-assisted extraction of cajaninstilbene acid and pinostrobin from pigeonpea leaves followed by RP-HPLC-DAD determination , 2010 .

[11]  Hanqi Zhang,et al.  Dynamic Microwave-assisted Extraction of Flavonoids from Radix Scutellariae * * Supported by the Dev , 2007 .

[12]  Xiangnian Fang,et al.  Kaempferol and quercetin isolated from Euonymus alatus improve glucose uptake of 3T3-L1 cells without adipogenesis activity. , 2008, Life sciences.

[13]  M. D. Luque de Castro,et al.  Soxhlet extraction of solid materials: an outdated technique with a promising innovative future , 1998 .

[14]  M. D. Luque de Castro,et al.  Multivariate optimisation of the microwave-assisted extraction of oleuropein and related biophenols from olive leaves , 2006, Analytical and bioanalytical chemistry.

[15]  Xiangmin Zhang,et al.  Fast determination of curcumol, curdione and germacrone in three species of Curcuma rhizomes by microwave-assisted extraction followed by headspace solid-phase microextraction and gas chromatography-mass spectrometry. , 2006, Journal of chromatography. A.

[16]  J. Luque‐Garcia,et al.  Where is microwave-based analytical equipment for solid sample pre-treatment going? , 2003 .

[17]  S. Mandal,et al.  Design and performance evaluation of a microwave based low carbon yielding extraction technique for naturally occurring bioactive triterpenoid: Oleanolic acid , 2010 .

[18]  C. Deng,et al.  Development of microwave-assisted extraction followed by headspace solid-phase microextraction and gas chromatography-mass spectrometry for quantification of camphor and borneol in Flos Chrysanthemi Indici. , 2006, Analytica chimica acta.

[19]  K. Ghafoor,et al.  Optimization of microwave-assisted extraction of active components from Chinese quince using response surface methodology , 2009 .

[20]  M. Palma,et al.  Microwave assisted extraction of anthocyanins from grape skins , 2011 .

[21]  Zhi-Qi Zhang,et al.  Analysis of Rodgersia aesculifolia Batal. Rhizomes by Microwave-Assisted Solvent Extraction and GC–MS , 2007 .

[22]  J. Bélanger,et al.  Influence of solvent, matrix dielectric properties, and applied power on the liquid-phase microwave-assisted processes (MAP™) extraction of ginger (Zingiber officinale) , 2003 .

[23]  S. Yao,et al.  Focused microwave-assisted solvent extraction and HPLC determination of effective constituents in Eucommia ulmodies Oliv. (E. ulmodies). , 2004, Talanta.

[24]  Zhuoyan Hu,et al.  Desirability function approach for the optimization of microwave-assisted extraction of saikosaponins from Radix Bupleuri , 2008 .

[25]  M D Luque de Castro,et al.  Focused microwave-assisted Soxhlet extraction: devices and applications. , 2004, Talanta.

[26]  Ligang Chen,et al.  Continuous determination of total flavonoids in Platycladus orientalis (L.) Franco by dynamic microwave-assisted extraction coupled with on-line derivatization and ultraviolet-visible detection. , 2007, Analytica chimica acta.

[27]  Nan Wu,et al.  Optimisation of microwave-assisted enzymatic extraction of corilagin and geraniin from Geranium sibiricum Linne and evaluation of antioxidant activity , 2010 .

[28]  D. Later,et al.  An accelerated solvent extraction system for the rapid preparation of environmental organic compounds in soil , 1995 .

[29]  H. Kadi,et al.  Kinetics study of microwave-assisted solvent extraction of oil from olive cake using hexane: comparison with the conventional extraction. , 2010 .

[30]  Luyan Zhang,et al.  Microwave-assisted extraction followed by capillary electrophoresis-amperometric detection for the determination of antioxidant constituents in Folium Eriobotryae. , 2008, Journal of chromatography. A.

[31]  S. Hemalatha,et al.  Microwave assisted extraction of curcumin by sample-solvent dual heating mechanism using Taguchi L9 orthogonal design. , 2008, Journal of pharmaceutical and biomedical analysis.

[32]  Pan,et al.  Microwave-assisted extraction of glycyrrhizic acid from licorice root. , 2000, Biochemical engineering journal.

[33]  Q. Su,et al.  Optimization of microwave-assisted solvent extraction for volatile organic acids in tobacco and its comparison with conventional extraction methods. , 2006, Analytica chimica acta.

[34]  U. Farooq,et al.  Optimized microwave-assisted extraction of phenolic acids from citrus mandarin peels and evaluation of antioxidant activity in vitro , 2009 .

[35]  G. G. Stokes "J." , 1890, The New Yale Book of Quotations.

[36]  Xin Wang,et al.  Optimization of ultrasonic/microwave assisted extraction (UMAE) of polysaccharides from Inonotus obliquus and evaluation of its anti-tumor activities. , 2010, International journal of biological macromolecules.

[37]  Stefano Mantegna,et al.  Improved extraction of vegetable oils under high-intensity ultrasound and/or microwaves. , 2008, Ultrasonics sonochemistry.

[38]  Xiu Deng,et al.  Microwave-assisted extraction of artemisinin from Artemisia annua L , 2002 .

[39]  S. Yao,et al.  Optimization and comparison of different extraction techniques for sanguinarine and chelerythrine in fruits of Macleaya cordata (Willd) R. Br. , 2005 .

[40]  C. Leonardi,et al.  Microwave assisted extraction of biodiesel feedstock from the seeds of invasive chinese tallow tree. , 2010, Environmental science & technology.

[41]  Xiao-hua Xiao,et al.  Application of ionic liquids in the microwave-assisted extraction of polyphenolic compounds from medicinal plants. , 2009, Talanta.

[42]  M. Stewart,et al.  Thiazolidinediones for type 2 diabetes. All glitazones may exacerbate heart failure. , 2001, BMJ.

[43]  Xiaosong Hu,et al.  Optimization of pectin extraction assisted by microwave from apple pomace using response surface methodology , 2007 .

[44]  Yan Li,et al.  Nitrogen-protected microwave-assisted extraction of ascorbic acid from fruit and vegetables. , 2009, Journal of separation science.

[45]  Junlong Wang,et al.  A comparison study on microwave-assisted extraction of Potentilla anserina L. polysaccharides with conventional method: Molecule weight and antioxidant activities evaluation , 2010 .

[46]  J. Dean,et al.  Extraction of organic pollutants from environmental matrices: selection of extraction technique , 2000 .

[47]  E. Pérez,et al.  The microwave-assisted process (MAPTM1): Extraction and determination of fat from cocoa powder and cocoa nibs , 2007 .

[48]  H. Wiedenfeld,et al.  Hypoglycemic effect of Equisetum myriochaetum aerial parts on streptozotocin diabetic rats. , 2000, Journal of ethnopharmacology.

[49]  X. Zhang,et al.  Quantitative determination of chlorogenic acid in Honeysuckle using microwave-assisted extraction followed by nano-LC-ESI mass spectrometry. , 2009, Talanta.

[50]  Jean-Paul Cadoret,et al.  Study on the microalgal pigments extraction process: Performance of microwave assisted extraction , 2011 .

[51]  Weiwei Zhai,et al.  Optimization of microwave-assisted extraction of anthocyanins from purple corn (Zea mays L.) cob and identification with HPLC–MS , 2010 .

[52]  E. Siochi,et al.  Basic ideas of microwave processing of polymers , 1993 .

[53]  Chunzhao Liu,et al.  Microwave-assisted extraction of chlorogenic acid from flower buds of Lonicera japonica Thunb. , 2008 .

[54]  Curtis L. Weller,et al.  Recent advances in extraction of nutraceuticals from plants , 2006 .

[55]  Simona Collina,et al.  Microwave-assisted extraction of coumarin and related compounds from Melilotus officinalis (L.) Pallas as an alternative to Soxhlet and ultrasound-assisted extraction. , 2006, Journal of chromatography. A.

[56]  Andrew G. Glen,et al.  APPL , 2001 .

[57]  Chunzhao Liu,et al.  Microwave-assisted extraction of scutellarin from Erigeron breviscapus Hand-Mazz and its determination by high-performance liquid chromatography. , 2007, Analytica chimica acta.

[58]  C. Delerue-Matos,et al.  Agar extraction from integrated multitrophic aquacultured Gracilaria vermiculophylla: evaluation of a microwave-assisted process using response surface methodology. , 2010, Bioresource technology.

[59]  J. Bélanger,et al.  High Performance Liquid Chromatography Determination Following Microwave Assisted Extraction of 3-Nitro-4-Hydroxyphenylarsonic Acid from Swine Liver, Kidney, and Muscle , 1994 .

[60]  S. Tsubaki,et al.  Microwave-assisted extraction of phenolic compounds from tea residues under autohydrolytic conditions , 2010 .

[61]  E. Björklund,et al.  Analytical-scale microwave-assisted extraction. , 2000, Journal of chromatography. A.

[62]  Ying Li,et al.  Improved solvent-free microwave extraction of essential oil from dried Cuminum cyminum L. and Zanthoxylum bungeanum Maxim. , 2006, Journal of chromatography. A.

[63]  Junlong Wang,et al.  A comparison study on microwave-assisted extraction of Artemisia sphaerocephala polysaccharides with conventional method: Molecule structure and antioxidant activities evaluation. , 2009, International journal of biological macromolecules.

[64]  Jean-Marie Desjobert,et al.  Antimicrobial activity and chemical composition of Origanum glandulosum Desf. essential oil and extract obtained by microwave extraction: Comparison with hydrodistillation , 2008 .

[65]  K. Ganzler,et al.  Effective sample preparation method for extracting biologically active compounds from different matrices by a microwave technique. , 1990, Journal of chromatography.

[66]  Á. Ríos,et al.  Supercritical fluid extraction: a critical review of its analytical usefulness , 2004 .

[67]  Y. Lan,et al.  Application of response surface methodology to optimize microwave-assisted extraction of silymarin from milk thistle seeds , 2009 .

[68]  S. Bradshaw,et al.  Solvent free microwave extraction of Elletaria cardamomum L.: A multivariate study of a new technique for the extraction of essential oil , 2007 .

[69]  Chunzhao Liu,et al.  Rapid determination of solanesol in tobacco by high-performance liquid chromatography with evaporative light scattering detection following microwave-assisted extraction. , 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[70]  M. Llompart,et al.  Microwave-assisted extraction: Application to the determination of emerging pollutants in solid samples. , 2010, Journal of chromatography. A.

[71]  S. Tsubaki,et al.  Isolation of hesperidin from peels of thinned Citrus unshiu fruits by microwave-assisted extraction. , 2010 .

[72]  Gui-hua Ruan,et al.  The study on the chromatographic fingerprint of Fructus xanthii by microwave assisted extraction coupled with GC-MS. , 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[73]  Xiangmin Zhang,et al.  Development of microwave-assisted extraction followed by headspace single-drop microextraction for fast determination of paeonol in traditional Chinese medicines. , 2006, Journal of chromatography. A.

[74]  Liu Zelong,et al.  Optimization and comparison of ultrasound/microwave assisted extraction (UMAE) and ultrasonic assisted extraction (UAE) of lycopene from tomatoes. , 2008, Ultrasonics sonochemistry.

[75]  Farid Chemat,et al.  Solvent-free microwave extraction of essential oil from aromatic herbs: comparison with conventional hydro-distillation. , 2004, Journal of chromatography. A.

[76]  Y. Zu,et al.  Optimisation of the microwave-assisted extraction process for four main astragalosides in Radix Astragali , 2010 .

[77]  Lujia Han,et al.  Microwave-assisted extraction of flavonoids from Radix Astragali , 2008 .

[78]  X. Xiao,et al.  Ionic liquid-based microwave-assisted extraction and HPLC analysis of dehydrocavidine in Corydalis saxicola Bunting. , 2010 .

[79]  Chunzhao Liu,et al.  Microwave-assisted extraction of solanesol from tobacco leaves. , 2006, Journal of chromatography. A.

[80]  Guonan Chen,et al.  An improved facile method for extraction and determination of steroidal saponins in Tribulus terrestris by focused microwave-assisted extraction coupled with GC-MS. , 2009, Journal of separation science.

[81]  Wenyan Ma,et al.  Ionic liquid-based microwave-assisted extraction of phenolic alkaloids from the medicinal plant Nelumbo nucifera Gaertn. , 2008, Journal of chromatography. A.

[82]  B. Aliakbarian,et al.  Extraction of phenolics from Vitis vinifera wastes using non-conventional techniques , 2010 .

[83]  Huizhou Liu,et al.  Microwave-assisted extraction of tea polyphenols and tea caffeine from green tea leaves , 2003 .

[84]  Huizhou Liu,et al.  Application of non-ionic surfactant in the microwave-assisted extraction of alkaloids from Rhizoma Coptidis. , 2008, Analytica chimica acta.

[85]  D. C. Esveld,et al.  Microwave-assisted extraction kinetics of terpenes from caraway seeds , 2005 .

[86]  Ligang Chen,et al.  DYNAMIC MICROWAVE-ASSISTED EXTRACTION OF FLAVONOIDS FROM HERBA EPIMEDII , 2008 .

[87]  Xiao-hua Xiao,et al.  Application of ionic liquids in the microwave-assisted extraction of trans-resveratrol from Rhizma Polygoni Cuspidati. , 2007, Journal of chromatography. A.

[88]  Ligang Chen,et al.  On-line coupling of dynamic microwave-assisted extraction with high-performance liquid chromatography for determination of andrographolide and dehydroandrographolide in Andrographis paniculata Nees. , 2007, Journal of chromatography. A.

[89]  Y. Zu,et al.  Optimization of microwave-assisted extraction of triterpene saponins from defatted residue of yellow horn (Xanthoceras sorbifolia Bunge.) kernel and evaluation of its antioxidant activity , 2010 .

[90]  V. Kuban,et al.  Combined microwave-assisted isolation and solid-phase purification procedures prior to the chromatographic determination of phenolic compounds in plant materials , 2004 .

[91]  R. C. Torrijos,et al.  Optimization of a microwave-assisted derivatization-extraction procedure for the determination of chlorophenols in ash samples , 2004 .

[92]  B. Ondruschka,et al.  Microwave-assisted extraction - : A state-of-the-art overview of varieties , 2006 .

[93]  Hanqi Zhang,et al.  Analysis of ginsenosides in Panax ginseng in high pressure microwave-assisted extraction. , 2008, Food chemistry.

[94]  Ligang Chen,et al.  Dynamic microwave-assisted extraction coupled with on-line spectrophotometric determination of safflower yellow in Flos Carthami. , 2006, Analytica chimica acta.