Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps
暂无分享,去创建一个
Christina A. Cuomo | Marjorie A. Oettinger | Charles Romeo | C. Cuomo | D. Ramsden | M. Gellert | D. Gent | M. Oettinger | Dik C. van Gent | Martin Gellert | J. McBlane | C. Romeo | J.Fraser McBlane | Dale A. Ramsden
[1] J. Menetski,et al. V(D)J recombination: Broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes , 1992, Cell.
[2] Kathryn S. Prickett,et al. A Short Polypeptide Marker Sequence Useful for Recombinant Protein Identification and Purification , 1988, Bio/Technology.
[3] E. Coen,et al. Transposable elements generate novel spatial patterns of gene expression in antirrhinum majus , 1986, Cell.
[4] M. Schlissel,et al. Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated. , 1993, Genes & development.
[5] S. Lewis,et al. The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses. , 1994, Advances in immunology.
[6] D. Schatz,et al. RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. , 1990, Science.
[7] S. Tonegawa,et al. RAG-l-Deficient Mice Have No Mature 8 and T Lymphocytes , 1992 .
[8] D. O'reilly,et al. Baculovirus expression vectors: a laboratory manual. , 1992 .
[9] F. Rougeon,et al. A V(D)J site-specific recombination model involving no compulsory double-stranded break formation at the coding segments. , 1992, Research in immunology.
[10] Robert Craigie,et al. HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer , 1991, Cell.
[11] D. Roth,et al. Characterization of broken DNA molecules associated with V(D)J recombination. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[12] M. Gellert,et al. Expression and V(D)J recombination activity of mutated RAG-1 proteins. , 1993, Nucleic acids research.
[13] J. Sambrook,et al. Molecular Cloning: A Laboratory Manual , 2001 .
[14] N. Craig. The mechanism of conservative site-specific recombination. , 1988, Annual review of genetics.
[15] D. Roth,et al. Characterization of coding ends in thymocytes of scid mice: implications for the mechanism of V(D)J recombination. , 1995, Immunity.
[16] M. Gellert,et al. Molecular analysis of V(D)J recombination. , 1992, Annual review of genetics.
[17] C. Cuomo,et al. Analysis of regions of RAG-2 important for V(D)J recombination. , 1994, Nucleic acids research.
[18] D. Schatz,et al. The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system , 1991, Cell.
[19] V. Stewart,et al. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement , 1992, Cell.
[20] O. Elroy-Stein,et al. New mammalian expression vectors , 1990, Nature.
[21] J. Menetski,et al. V(D)J recombination in mouse thymocytes: Double-strand breaks near T cell receptor δ rearrangement signals , 1992, Cell.
[22] N. Rosenberg,et al. An active v-abl protein tyrosine kinase blocks immunoglobulin light-chain gene rearrangement. , 1994, Genes & development.
[23] D. Ramsden,et al. Formation and resolution of double-strand break intermediates in V(D)J rearrangement. , 1995, Genes & development.
[24] J E Hesse,et al. Definition of a core region of RAG-2 that is functional in V(D)J recombination. , 1994, Nucleic acids research.
[25] M. Lieber,et al. V(D)J recombination: a functional definition of the joining signals. , 1989, Genes & development.
[26] D. V. van Gent,et al. RAG-1 mutations that affect the target specificity of V(D)j recombination: a possible direct role of RAG-1 in site recognition. , 1995, Genes & development.
[27] D. Baltimore,et al. Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[28] D. Ramsden,et al. Initiation of V(D)J recombination in a cell-free system , 1995, Cell.
[29] David Baltimore,et al. The V(D)J recombination activating gene, RAG-1 , 1989, Cell.
[30] K. Mizuuchi,et al. Inversion of the phosphate chirality at the target site of Mu DNA strand transfer: Evidence for a one-step transesterification mechanism , 1991, Cell.
[31] Susumu Tonegawa,et al. RAG-1-deficient mice have no mature B and T lymphocytes , 1992, Cell.