Influence of the FID and off‐resonance effects in dense MRI

Accurate functional measurement in cardiovascular diseases is important as inaccuracy may compromise diagnostic decisions. Cardiac function can be assessed using displacement encoding with stimulated echoes, resulting in three signal components. The free induction decay (FID), arising from spins undergoing T1‐relaxation, is not displacement encoded and impairs the displacement acquired. Techniques for suppressing the FID exist; however, a residual will remain. The effect of the residual is difficult to distinguish and investigate in vitro and in vivo. In this work, the influence of the FID as well as of off‐resonance effects is evaluated by altering the phase of the FID in relation to the stimulated echo. The results show that the FID and off‐resonance effects can impair the accuracy of the displacement measurement acquired. The influence of the FID can be avoided by using an encoded reference. We therefore recommend the assessment of this influence of the FID for each displacement encoding with stimulated echoes protocol. Magn Reson Med, 2010. © 2010 Wiley‐Liss, Inc.

[1]  Y. Fung.  Foundations of solid mechanics , 1965 .

[2]  S. Maier,et al.  Improved myocardial tagging contrast , 1993, Magnetic resonance in medicine.

[3]  H. Wen,et al.  DENSE: displacement encoding with stimulated echoes in cardiac functional MRI. , 1999, Journal of magnetic resonance.

[4]  E R McVeigh,et al.  In vivo measurement of T*2 and field inhomogeneity maps in the human heart at 1.5 T , 1998, Magnetic resonance in medicine.

[5]  Bruce S Spottiswoode,et al.  Selective suppression of artifact‐generating echoes in cine DENSE using through‐plane dephasing , 2006, Magnetic resonance in medicine.

[6]  H. Wen,et al.  Mixed echo train acquisition displacement encoding with stimulated echoes: An optimized DENSE method for in vivo functional imaging of the human heart , 2001, Magnetic resonance in medicine.

[7]  P. Bendel,et al.  Snapshot MRI with T2*‐weighted magnetization preparation , 1993, Magnetic resonance in medicine.

[8]  Yu-Chung N. Cheng,et al.  Magnetic Resonance Imaging: Physical Principles and Sequence Design , 1999 .

[9]  Andrew E Arai,et al.  meta-DENSE complex acquisition for reduced intravoxel dephasing. , 2004, Journal of magnetic resonance.

[10]  S. Fraser,et al.  Circumferential Strain in the Wall of the Common Carotid Artery: Comparing Displacement-encoded and Cine Mri in Volunteers Nih Public Access Materials and Methods , 2022 .

[11]  Frederick H Epstein,et al.  Displacement‐encoded cardiac MRI using cosine and sine modulation to eliminate (CANSEL) artifact‐generating echoes , 2004, Magnetic resonance in medicine.

[12]  Patrick A Helm,et al.  Balanced multipoint displacement encoding for DENSE MRI , 2009, Magnetic resonance in medicine.

[13]  F. Epstein,et al.  Complementary displacement‐encoded MRI for contrast‐enhanced infarct detection and quantification of myocardial function in mice , 2004, Magnetic resonance in medicine.

[14]  Christopher M Kramer,et al.  Myocardial tissue tracking with two-dimensional cine displacement-encoded MR imaging: development and initial evaluation. , 2004, Radiology.