Disseminated Gonococcal Infection Presenting as Sweet Syndrome

The salient features of Sweet syndrome, also known as acute febrile neutrophilic dermatosis, are pyrexia, elevated neutrophil count, painful red papules, nodules, plaques, and an infiltrate that consists mainly of mature neutrophils diffusely distributed in the upper dermis. In addition to idiopathic forms of the syndrome, malignancies, inflammatory bowel disease, infections, pregnancy, and drugs have been associated with Sweet syndrome. Disseminated gonococcal infection (DGI) results from bacteremic dissemination of Neisseria gonorrhoeae. The most common presentation of DGI is arthritis-dermatitis syndrome. About 75% of DGI patients display a characteristic dermatitis consisting of discrete papules and pustules, often with a hemorrhagic component. We report a case of DGI presenting as Sweet syndrome. (Korean J Med 2011;80:486-489)

[1]  Makoto Ohnishi,et al.  [Neisseria gonorrhoeae]. , 2010, Nihon rinsho. Japanese journal of clinical medicine.

[2]  A. Ribeiro,et al.  [Acute febrile neutrophilic dermatosis - Sweet's syndrome]. , 2009, Acta reumatologica portuguesa.

[3]  P. Pantelidis,et al.  Disseminated gonococcal infection in a homosexual man diagnosed by nucleic acid amplification testing from a skin lesion swab , 2008, Sexually Transmitted Infections.

[4]  N. Holder.  Gonococcal infections. , 2008, Pediatrics in review.

[5]  L. Yee,et al.  Disseminated gonococcal infection presenting as vasculitis: a case report , 2007, Journal of Clinical Pathology.

[6]  T. Bardin.  Gonococcal arthritis. , 2003, Best practice & research. Clinical rheumatology.

[7]  Philip R. Cohen,et al.  Trimethoprim-sulfamethoxazole-associated acute febrile neutrophilic dermatosis: case report and review of drug-induced Sweet's syndrome. , 1996, Journal of the American Academy of Dermatology.

[8]  W. Su,et al.  Sweet's syndrome: systemic signs and symptoms and associated disorders. , 1995, Mayo Clinic proceedings.

[9]  P. Driesch.  Sweet's syndrome (acute febrile neutrophilic dermatosis) , 1994 .

[10]  T. Kuo,et al.  SWEET'S SYNDROME: CLINICOPATHOLOGIC STUDY OF ELEVEN CASES , 1994, International journal of dermatology.

[11]  F. Loconsole,et al.  Cutaneous vasculitis as the sole manifestation of disseminated gonococcal infection: case report. , 1994, Genitourinary medicine.

[12]  Philip R. Cohen,et al.  Sweet's syndrome and cancer and cancer , 1993 .

[13]  J. Saurat,et al.  The incidence of Sweet's syndrome in Geneva. A retrospective study of 29 cases. , 1993, Dermatology.

[14]  Philip R. Cohen,et al.  Sweet's syndrome and cancer. , 1993, Clinics in dermatology.

[15]  Philip R. Cohen,et al.  Concurrent Sweet's syndrome and erythema nodosum: a report, world literature review and mechanism of pathogenesis. , 1992, The Journal of rheumatology.

[16]  Philip R. Cohen,et al.  The pathogenesis of Sweet's syndrome. , 1991, Journal of the American Academy of Dermatology.

[17]  J. Hunter,et al.  Sweet's syndrome: a clinicopathologic review of twenty-nine cases. , 1990, Journal of the American Academy of Dermatology.

[18]  R. Kurzrock,et al.  Acute febrile neutrophilic dermatosis. , 1989, American family physician.

[19]  B. Britigan,et al.  Gonococcal infection: a model of molecular pathogenesis. , 1985, The New England journal of medicine.

[20]  R. Sweet.  Acute febrile neutrophilic dermatosis–1978 , 1979, The British journal of dermatology.

[21]  John E. Bennett,et al.  Principles and practice of infectious diseases. Vols 1 and 2. , 1979 .

[22]  Douglas S. Kellogg,et al.  NEISSERIA GONORRHOEAE I , 1963, Journal of bacteriology.