Intragraft B cell differentiation during the development of tolerance to kidney allografts is associated with a regulatory B cell signature revealed by single cell transcriptomics

[1]  M. Lauss,et al.  B Cells and Tertiary Lymphoid Structures: Friends or Foes in Cancer Immunotherapy? , 2021, Clinical cancer research : an official journal of the American Association for Cancer Research.

[2]  R. Colvin,et al.  Novel intragraft regulatory lymphoid structures in kidney allograft tolerance , 2021, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[3]  M. Bono,et al.  The Multifaceted Roles of B Cells in the Thymus: From Immune Tolerance to Autoimmunity , 2021, Frontiers in Immunology.

[4]  Hong Jiang,et al.  Single-Cell RNA Sequencing Reveals the Immunological Profiles of Renal Allograft Rejection in Mice , 2021, Frontiers in Immunology.

[5]  N. Neretti,et al.  Single-cell transcriptomics of peripheral blood in the aging mouse , 2021, bioRxiv.

[6]  D. Landsittel,et al.  Transitional B cell cytokines predict renal allograft outcomes , 2021, Science Translational Medicine.

[7]  A. Cherukuri,et al.  Regulatory B cells: TIM‐1, transplant tolerance, and rejection , 2021, Immunological reviews.

[8]  Y. Pylayeva-Gupta,et al.  Regulatory B cells in cancer , 2020, Immunological reviews.

[9]  C. Sautès-Fridman,et al.  B cells and cancer: To B or not to B? , 2020, The Journal of experimental medicine.

[10]  Raphael Gottardo,et al.  Integrated analysis of multimodal single-cell data , 2020, Cell.

[11]  R. Colvin,et al.  Kidney-induced systemic tolerance of heart allografts in mice , 2020, JCI insight.

[12]  Heather H Gustafson,et al.  Trajectory analysis quantifies transcriptional plasticity during macrophage polarization , 2020, Scientific Reports.

[13]  N. Rogers,et al.  Transplant Tolerance Induction: Insights From the Liver , 2020, Frontiers in Immunology.

[14]  T. Jin,et al.  Transitional B cells involved in autoimmunity and their impact on neuroimmunological diseases , 2020, Journal of Translational Medicine.

[15]  J. Leventhal,et al.  Outstanding questions in transplantation: Tolerance , 2020, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[16]  O. Britanova,et al.  B cells, plasma cells and antibody repertoires in the tumour microenvironment , 2020, Nature Reviews Immunology.

[17]  Chao Yang,et al.  Plasmacytoid Dendritic Cell–driven Induction of Treg Is Strain Specific and Correlates With Spontaneous Acceptance of Kidney Allografts , 2020, Transplantation.

[18]  M. Cancro,et al.  Molecular pattern recognition in peripheral B cell tolerance: lessons from age-associated B cells. , 2019, Current opinion in immunology.

[19]  Tianliang Li,et al.  Siglec-G Deficiency Ameliorates Hyper-Inflammation and Immune Collapse in Sepsis via Regulating Src Activation , 2019, Front. Immunol..

[20]  V. Greiff,et al.  Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow , 2019, bioRxiv.

[21]  Paul J. Hoffman,et al.  Comprehensive Integration of Single-Cell Data , 2018, Cell.

[22]  Andrew J. Hill,et al.  The single cell transcriptional landscape of mammalian organogenesis , 2019, Nature.

[23]  Lai Guan Ng,et al.  Dimensionality reduction for visualizing single-cell data using UMAP , 2018, Nature Biotechnology.

[24]  L. Turka,et al.  Biomarkers of operational tolerance following kidney transplantation - The immune tolerance network studies of spontaneously tolerant kidney transplant recipients. , 2018, Human immunology.

[25]  Bo Peng,et al.  Regulatory B cells: the cutting edge of immune tolerance in kidney transplantation , 2018, Cell Death & Disease.

[26]  M. McCarter,et al.  Antigen-Presenting Intratumoral B Cells Affect CD4+ TIL Phenotypes in Non–Small Cell Lung Cancer Patients , 2017, Cancer Immunology Research.

[27]  Hannah A. Pliner,et al.  Reversed graph embedding resolves complex single-cell trajectories , 2017, Nature Methods.

[28]  T. Fest,et al.  Mature IgM-expressing plasma cells sense antigen and develop competence for cytokine production upon antigenic challenge , 2016, Nature Communications.

[29]  Y. Louzoun,et al.  Self-Antigen-Driven Thymic B Cell Class Switching Promotes T Cell Central Tolerance. , 2016, Cell reports.

[30]  P. Stepnowski,et al.  Current methods of the analysis of immunosuppressive agents in clinical materials: A review. , 2016, Journal of pharmaceutical and biomedical analysis.

[31]  Melissa M. Sprachman,et al.  SCS macrophages suppress melanoma by restricting tumor-derived vesicle–B cell interactions , 2016, Science.

[32]  D. Kreisel,et al.  The Role of Lymphoid Neogenesis in Allografts , 2016, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[33]  G. Lal,et al.  Interleukin-10 From Marginal Zone Precursor B-Cell Subset Is Required for Costimulatory Blockade-Induced Transplantation Tolerance , 2015, Transplantation.

[34]  P. Marrack,et al.  Age-Associated B Cells: A T-bet–Dependent Effector with Roles in Protective and Pathogenic Immunity , 2015, The Journal of Immunology.

[35]  D. Kreisel,et al.  Organ-specific differences in achieving tolerance , 2015, Current opinion in organ transplantation.

[36]  Wei Yang,et al.  Thymic B cells promote thymus-derived regulatory T cell development and proliferation. , 2015, Journal of autoimmunity.

[37]  C. Daniel,et al.  Siglec-G Deficiency Leads to Autoimmunity in Aging C57BL/6 Mice , 2015, The Journal of Immunology.

[38]  James A. Hutchinson,et al.  DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance. , 2015, Immunity.

[39]  E. Rosser,et al.  Regulatory B cells: origin, phenotype, and function. , 2015, Immunity.

[40]  Christopher J. Kane,et al.  Immunosuppressive plasma cells impede T cell-dependent immunogenic chemotherapy , 2015, Nature.

[41]  T. Tedder.  B10 Cells: A Functionally Defined Regulatory B Cell Subset , 2015, The Journal of Immunology.

[42]  T. Kurosaki,et al.  Memory B cells , 2015, Nature Reviews Immunology.

[43]  K. Takeda,et al.  Interleukin-10-producing plasmablasts exert regulatory function in autoimmune inflammation. , 2014, Immunity.

[44]  W. Huber,et al.  Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.

[45]  S. Grey,et al.  A Role for Intrathymic B Cells in the Generation of Natural Regulatory T Cells , 2014, The Journal of Immunology.

[46]  T. Winkler,et al.  The Ligand-Binding Domain of Siglec-G Is Crucial for Its Selective Inhibitory Function on B1 Cells , 2014, The Journal of Immunology.

[47]  Cole Trapnell,et al.  Pseudo-temporal ordering of individual cells reveals dynamics and regulators of cell fate decisions , 2014, Nature Biotechnology.

[48]  Amit Bar-Or,et al.  IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases , 2014, Nature.

[49]  T. Sparwasser,et al.  Infiltrating Foxp3+ Regulatory T Cells From Spontaneously Tolerant Kidney Allografts Demonstrate Donor‐Specific Tolerance , 2013, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[50]  S. Brouard,et al.  Regulatory B Cells and Tolerance in Transplantation: From Animal Models to Human , 2013, Front. Immunol..

[51]  Antonio Lanzavecchia,et al.  A functional BCR in human IgA and IgM plasma cells. , 2013, Blood.

[52]  T. Kurosaki.  Regulation of BCR signaling. , 2011, Molecular immunology.

[53]  R. Colvin,et al.  Early acceptance of renal allografts in mice is dependent on foxp3(+) cells. , 2011, The American journal of pathology.

[54]  K. Lamb,et al.  Long‐Term Renal Allograft Survival in the United States: A Critical Reappraisal , 2011, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[55]  Randy D. Gascoyne,et al.  The pre-B-cell receptor associated protein VpreB3 is a useful diagnostic marker for identifying c-MYC translocated lymphomas , 2010, Haematologica.

[56]  M. Suthanthiran,et al.  Identification of a B cell signature associated with renal transplant tolerance in humans. , 2010, The Journal of clinical investigation.

[57]  R. Jessberger,et al.  Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response. , 2009, Immunity.

[58]  E. Riley,et al.  IL-10: The Master Regulator of Immunity to Infection , 2008, The Journal of Immunology.

[59]  S. Pillai,et al.  Peripheral B cell subsets. , 2008, Current opinion in immunology.

[60]  C. Blanco-Betancourt,et al.  Binding of Free Immunoglobulin Light Chains to VpreB3 Inhibits Their Maturation and Secretion in Chicken B Cells* , 2004, Journal of Biological Chemistry.

[61]  M. Sykes,et al.  Mechanisms of transplant tolerance induction using costimulatory blockade. , 2002, Current opinion in immunology.

[62]  J. Monroe,et al.  CD23 defines two distinct subsets of immature B cells which differ in their responses to T cell help signals. , 2002, International immunology.

[63]  K. Calame,et al.  Plasma cells: finding new light at the end of B cell development , 2001, Nature Immunology.

[64]  Fadi G Lakkis,et al.  Immunologic ‘ignorance’ of vascularized organ transplants in the absence of secondary lymphoid tissue , 2000, Nature Medicine.

[65]  C. Schiff,et al.  VPREB3: cDNA characterization and expression in human and chromosome mapping in human and mouse , 2000, Cytogenetic and Genome Research.

[66]  T. Winkler,et al.  Precursor B Cell Receptor–Dependent B Cell Proliferation and Differentiation Does Not Require the Bone Marrow or Fetal Liver Environment , 2000, The Journal of experimental medicine.

[67]  T. Takemori,et al.  Molecular components and assembly of mu.surrogate light chain complexes in pre-B cell lines. , 1994, The Journal of biological chemistry.

[68]  J. Plate,et al.  Kidney transplants in mice. An analysis of the immune status of mice bearing long-term, H-2 incompatible transplants , 1978, The Journal of experimental medicine.

[69]  P. Russell,et al.  Induced immune destruction of long-surviving, H-2 incompatible kidney transplants in mice , 1978, The Journal of experimental medicine.