Excitability, memory and oscillations in artificial acetylcholinesterase membranes

Abstract Experimental evidence is presented for excitability, memory, and oscillations in artificial acetylcholinesterase membranes. Membranes were produced with crosslinked albumin and gelatin. Potential differences were measured under steady-state conditions as a function of the amount of injected acetylcholine with and without acetylcholinesterase activity in the membrane.

[1]  R. Arndt,et al.  Theory of excitable membranes. I. A simple model for a three-state artificial membrane. , 1975, Journal of theoretical biology.

[2]  R. Gasser,et al.  Adsorbed Oxygen Inhibition of Reactions of Hydrogen with Tungsten , 1972 .

[3]  H. Goudeau,et al.  Electrically excitable artificial membranes , 1965 .

[4]  M Huchet,et al.  Purification of membrane fragments derived from the non excitable surface of the eel electroplax , 1970, FEBS letters.

[5]  D. Thomas,et al.  [63] Artificial enzyme membranes , 1976 .

[6]  D. Thomas,et al.  ELECTRON MICROSCOPIC AND KINETIC STUDIES DEALING WITH AN ARTIFICIAL ENZYME MEMBRANE APPLICATION TO A CYTOCHEMICAL MODEL WITH THE HORSERADISH PEROXIDASE-3,3'-DIAMINOBENZIDINE SYSTEM , 1974, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[7]  R. Blumenthal,et al.  The coupling of an enzymatic reaction to transmembrane flow of electric current in a synthetic "active transport" system. , 1967, Biophysical journal.

[8]  R. Goldman,et al.  Papain Membrane on a Collodion Matrix: Preparation and Enzymic Behavior , 1965, Science.

[9]  Z. Hall.  Release of neurotransmitters and their interaction with receptors. , 1972, Annual review of biochemistry.

[10]  J. Changeux,et al.  Séparation de membranes excitables à partir de l'organe électrique d'Electrophorus electricus. , 1969 .

[11]  J P Changeux,et al.  Structural and functional properties of the acetylcholine receptor protein in its purified and membrane-bound states. , 1978, Annual review of biochemistry.

[12]  D Thomas,et al.  An experimental enzyme-membrane oscillator. , 1973, Biochimica et biophysica acta.

[13]  F. Offner.  The excitable membrane. A physiochemical model. , 1972, Biophysical journal.

[14]  Daniel Thomas,et al.  ELECTRON MICROSCOPIC AND KINETIC STUDIES DEALING WITH AN ARTIFICIAL ENZYME MEMBRANE , 1974 .

[15]  J. Changeux,et al.  Electrical Phenomena Associated with the Activity of the Membrane-Bound Acetylcholinesterase , 1967, Science.