Synthesis and Characterization of Amphiphilic Poly(caprolactone) Star Block Copolymers

Novel, star-shaped, amphiphilic block copolymers composed of fully degradable poly(caprolactone) were synthesized by sequential addition polymerization. In the first step, four-arm macroinitiators were produced by ring-opening polymerization of caprolactone by initiation with pentaerythritol. Then, block copolymers were synthesized by sequential addition of 4-(2-benzyloxyethyl)-e-caprolactone to the four-arm macroinitators. Star-shaped, amphiphilic block copolymers containing poly(caprolactone)-block-poly[4-(2-hydroxyethyl)caprolactone] segments were obtained by catalytic debenzylation.

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