Implementation and Use of Disease Diagnosis Systems for Electronic Medical Records Based on Machine Learning: A Complete Review

Electronic health records are used to extract patient’s information instantly and remotely, which can help to keep track of patients’ due dates for checkups, immunizations, and to monitor health performance. The Health Insurance Portability and Accountability Act (HIPAA) in the USA protects the patient data confidentiality, but it can be used if data is re-identified using ‘HIPAA Safe Harbor’ technique. Usually, this re-identification is performed manually, which is very laborious and time captivating exertion. Various techniques have been proposed for automatic extraction of useful information, and accurate diagnosis of diseases. Most of these methods are based on Machine Learning and Deep Learning Methods, while the auxiliary diagnosis is performed using Rule-based methods. This review focuses on recently published papers, which are categorized into Rule-Based Methods, Machine Learning (ML) Methods, and Deep Learning (DL) Methods. Particularly, ML methods are further categorized into Support Vector Machine Methods (SVM), Bayes Methods, and Decision Tree Methods (DT). DL methods are decomposed into Convolutional Neural Networks (CNN), Recurrent Neural Networks (RNN), Deep Belief Network (DBN) and Autoencoders (AE) methods. The objective of this survey paper is to highlight both the strong and weak points of various proposed techniques in the disease diagnosis. Moreover, we present advantage, disadvantage, focused disease, dataset employed, and publication year of each category.

[1]  K. M. Zubair Hasan,et al.  Automated Prediction of Heart Disease Patients using Sparse Discriminant Analysis , 2019, 2019 International Conference on Electrical, Computer and Communication Engineering (ECCE).

[2]  Volker Tresp,et al.  Predicting Clinical Events by Combining Static and Dynamic Information Using Recurrent Neural Networks , 2016, 2016 IEEE International Conference on Healthcare Informatics (ICHI).

[3]  Riku Turkki,et al.  Deep learning for tissue microarray image-based outcome prediction in patients with colorectal cancer , 2016, SPIE Medical Imaging.

[4]  Tom White,et al.  Hadoop: The Definitive Guide , 2009 .

[5]  Fei Wang,et al.  Measuring Patient Similarities via a Deep Architecture with Medical Concept Embedding , 2016, 2016 IEEE 16th International Conference on Data Mining (ICDM).

[6]  Mohammad Alodadi,et al.  Radiology Clinical Notes Mining Using Weighted Association Rules , 2017, 2017 IEEE International Conference on Healthcare Informatics (ICHI).

[7]  William R. Hersh,et al.  The Electronic Medical Record: Promises and Problems , 1995, J. Am. Soc. Inf. Sci..

[8]  B. van Ginneken,et al.  Deep learning as a tool for increased accuracy and efficiency of histopathological diagnosis , 2016, Scientific Reports.

[9]  Jianqiang Li,et al.  Comparative Analysis of Vessel Segmentation Techniques in Retinal Images , 2019, IEEE Access.

[10]  Yongfeng Huang,et al.  Optimization of CNN through Novel Training Strategy for Visual Classification Problems , 2018, Entropy.

[11]  M Anbarasi,et al.  ENHANCED PREDICTION OF HEART DISEASE WITH FEATURE SUBSET SELECTION USING GENETIC ALGORITHM , 2010 .

[12]  Yuan Luo,et al.  Recurrent Neural Networks for Classifying Relations in Clinical Notes , 2017, AMIA.

[13]  Yongfeng Huang,et al.  CSFL: A novel unsupervised convolution neural network approach for visual pattern classification , 2017, AI Communications.

[14]  S. Donn Patient Safety in the Context of Neonatal Intensive Care: Research and Educational Opportunities , 2012 .

[15]  Eric S. Kirkendall,et al.  Phenotyping for patient safety: algorithm development for electronic health record based automated adverse event and medical error detection in neonatal intensive care , 2014, Journal of the American Medical Informatics Association : JAMIA.

[16]  Li Zhang,et al.  Deep similarity learning for multimodal medical images , 2018, Comput. methods Biomech. Biomed. Eng. Imaging Vis..

[17]  Cosmin Adrian Bejan,et al.  Pneumonia identification using statistical feature selection , 2012, J. Am. Medical Informatics Assoc..

[18]  Hongfang Liu,et al.  Temporal Pattern and Association Discovery of Diagnosis Codes Using Deep Learning , 2015, 2015 International Conference on Healthcare Informatics.

[19]  Obaid Ur Rehman,et al.  A Benchmark Dataset and Learning High-Level Semantic Embeddings of Multimedia for Cross-Media Retrieval , 2018, IEEE Access.

[20]  Gabriel J. Brostow,et al.  Automated Retinopathy of Prematurity Case Detection with Convolutional Neural Networks , 2016, LABELS/DLMIA@MICCAI.

[21]  D P Connelly,et al.  Knowledge-based systems in laboratory medicine and pathology. A review and survey of the field. , 1987, Archives of pathology & laboratory medicine.

[22]  Murthy V. Devarakonda,et al.  An NLP-based cognitive system for disease status identification in electronic health records , 2017, 2017 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI).

[23]  John F. Hurdle,et al.  Extracting Information from Textual Documents in the Electronic Health Record: A Review of Recent Research , 2008, Yearbook of Medical Informatics.

[24]  Shichao Zhang,et al.  Association Rule Mining: Models and Algorithms , 2002 .

[25]  Moh. Faturrahman,et al.  Structural MRI classification for Alzheimer's disease detection using deep belief network , 2017, 2017 11th International Conference on Information & Communication Technology and System (ICTS).

[26]  J. Kazmierska,et al.  Application of the Naïve Bayesian Classifier to optimize treatment decisions. , 2008, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[27]  Mark D Cicero,et al.  Training and Validating a Deep Convolutional Neural Network for Computer-Aided Detection and Classification of Abnormalities on Frontal Chest Radiographs , 2017, Investigative radiology.

[28]  Rui Zhang,et al.  Automatic methods to extract New York heart association classification from clinical notes , 2017, 2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM).

[29]  Christopher G Chute,et al.  A high throughput semantic concept frequency based approach for patient identification: a case study using type 2 diabetes mellitus clinical notes. , 2010, AMIA ... Annual Symposium proceedings. AMIA Symposium.

[30]  Varinder Pabbi,et al.  Fuzzy Expert System for Medical Diagnosis , 2015 .

[31]  Waldo Hasperué,et al.  The master algorithm: how the quest for the ultimate learning machine will remake our world , 2015 .

[32]  U Joseph Schoepf,et al.  CT angiography for diagnosis of pulmonary embolism: state of the art. , 2004, Radiology.

[33]  Cynthia Brandt,et al.  Semi-supervised clinical text classification with Laplacian SVMs: An application to cancer case management , 2013, J. Biomed. Informatics.

[34]  Dayong Wang,et al.  Deep Learning for Identifying Metastatic Breast Cancer , 2016, ArXiv.

[35]  S. Normand,et al.  Positive predictive value of the diagnosis of acute myocardial infarction in an administrative database , 1999, Journal of General Internal Medicine.

[36]  Yang Liu,et al.  Lack of Association Between Electronic Health Record Systems and Improvement in Use of Evidence‐Based Heart Failure Therapies in Outpatient Cardiology Practices , 2012, Clinical cardiology.

[37]  Li Li,et al.  Deep Patient: An Unsupervised Representation to Predict the Future of Patients from the Electronic Health Records , 2016, Scientific Reports.

[38]  Sholom M. Weiss,et al.  Rule-based Machine Learning Methods for Functional Prediction , 1995, J. Artif. Intell. Res..

[39]  Ping Zhang,et al.  Risk Prediction with Electronic Health Records: A Deep Learning Approach , 2016, SDM.

[40]  K. Jobst,et al.  Accurate Prediction of Histologically Confirmed Alzheimer's Disease and the Differential Diagnosis of Dementia: The Use of NINCDS-ADRDA and DSM-III-R Criteria, SPECT, X-Ray CT, and Apo E4 in Medial Temporal Lobe Dementias , 1997, International Psychogeriatrics.

[41]  Satoshi Sekine,et al.  A survey of named entity recognition and classification , 2007 .

[42]  Mark J. Schreiber,et al.  Decision Tree Algorithms Predict the Diagnosis and Outcome of Dengue Fever in the Early Phase of Illness , 2008, PLoS neglected tropical diseases.

[43]  Hua Xu,et al.  Applying active learning to high-throughput phenotyping algorithms for electronic health records data. , 2013, Journal of the American Medical Informatics Association : JAMIA.

[44]  Jimeng Sun,et al.  Using recurrent neural network models for early detection of heart failure onset , 2016, J. Am. Medical Informatics Assoc..

[45]  Zhiqiang Geng,et al.  A new deep belief network based on RBM with glial chains , 2018, Inf. Sci..

[46]  M. Shamim Hossain,et al.  Recurrent convolutional neural network based multimodal disease risk prediction , 2019, Future Gener. Comput. Syst..

[47]  Yen-Wei Chen,et al.  HEp-2 Cell Classification Using K-Support Spatial Pooling in Deep CNNs , 2016, LABELS/DLMIA@MICCAI.

[48]  Xiaopeng Wei,et al.  Predicting the Risk of Heart Failure With EHR Sequential Data Modeling , 2018, IEEE Access.

[49]  Sahar Kianian,et al.  Diagnosis of attention deficit hyperactivity disorder using deep belief network based on greedy approach , 2017, 2017 5th International Symposium on Computational and Business Intelligence (ISCBI).

[50]  S. Brunak,et al.  Mining electronic health records: towards better research applications and clinical care , 2012, Nature Reviews Genetics.

[51]  Huilong Duan,et al.  Using neural attention networks to detect adverse medical events from electronic health records , 2018, J. Biomed. Informatics.

[52]  Vladimir Vapnik,et al.  An overview of statistical learning theory , 1999, IEEE Trans. Neural Networks.

[53]  Adam Wright,et al.  Comparison of Association Rule Mining and Crowdsourcing for Automated Generation of a Problem-Medication Knowledge Base , 2012, 2012 IEEE Second International Conference on Healthcare Informatics, Imaging and Systems Biology.

[54]  Carol Friedman,et al.  Methods for Identifying Suicide or Suicidal Ideation in EHRs , 2012, AMIA.

[55]  Igor Kononenko,et al.  Inductive and Bayesian learning in medical diagnosis , 1993, Appl. Artif. Intell..

[56]  Joshua C. Denny,et al.  Phenotyping Adverse Drug Reactions: Statin-Related Myotoxicity , 2015, AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science.

[57]  Søren Brunak,et al.  Using Electronic Patient Records to Discover Disease Correlations and Stratify Patient Cohorts , 2011, PLoS Comput. Biol..

[58]  Hadi Rezaeilouyeh,et al.  Microscopic medical image classification framework via deep learning and shearlet transform , 2016, Journal of medical imaging.

[59]  Tingting Xu,et al.  Predicting Chronic Disease Hospitalizations from Electronic Health Records: An Interpretable Classification Approach , 2018, Proceedings of the IEEE.

[60]  Ali Hassan Sodhro,et al.  A Joint Deep Learning and Internet of Medical Things Driven Framework for Elderly Patients , 2020, IEEE Access.

[61]  Kung-Min Wang,et al.  Modeling and predicting the occurrence of brain metastasis from lung cancer by Bayesian network: A case study of Taiwan , 2014, Comput. Biol. Medicine.

[62]  Yee Whye Teh,et al.  A Fast Learning Algorithm for Deep Belief Nets , 2006, Neural Computation.

[63]  Dalin Zhang,et al.  Diagnosis and Analysis of Diabetic Retinopathy Based on Electronic Health Records , 2019, IEEE Access.

[64]  R. Chang,et al.  Data mining with decision trees for diagnosis of breast tumor in medical ultrasonic images , 2001, Breast Cancer Research and Treatment.

[65]  Son Doan,et al.  Application of information technology: MedEx: a medication information extraction system for clinical narratives , 2010, J. Am. Medical Informatics Assoc..

[66]  Yihan Deng,et al.  Towards automatic encoding of medical procedures using convolutional neural networks and autoencoders , 2019, Artif. Intell. Medicine.

[67]  Dexian Huang,et al.  Data-driven soft sensor development based on deep learning technique , 2014 .

[68]  Aman Tyagi,et al.  Asthma diagnosis and level of control using decision tree and fuzzy system , 2014 .

[69]  Stephen B. Johnson,et al.  A review of approaches to identifying patient phenotype cohorts using electronic health records , 2013, J. Am. Medical Informatics Assoc..

[70]  Jimeng Sun,et al.  Explainable Prediction of Medical Codes from Clinical Text , 2018, NAACL.

[71]  Yunlei Sun,et al.  The Neural Network of One-Dimensional Convolution-An Example of the Diagnosis of Diabetic Retinopathy , 2019, IEEE Access.

[72]  Hayit Greenspan,et al.  Chest pathology identification using deep feature selection with non-medical training , 2018, Comput. methods Biomech. Biomed. Eng. Imaging Vis..

[73]  Yongfeng Huang,et al.  Facebook5k: A Novel Evaluation Resource Dataset for Cross-Media Search , 2018, ICCCS.

[74]  Edward Kim,et al.  A deep semantic mobile application for thyroid cytopathology , 2016, SPIE Medical Imaging.

[75]  Sven Loncaric,et al.  Detection of exudates in fundus photographs using deep neural networks and anatomical landmark detection fusion , 2016, Comput. Methods Programs Biomed..

[76]  Peter Kokol,et al.  Contrasting temporal trend discovery for large healthcare databases , 2014, Comput. Methods Programs Biomed..

[77]  Lijun Qian,et al.  Transfer bi-directional LSTM RNN for named entity recognition in Chinese electronic medical records , 2017, 2017 IEEE 19th International Conference on e-Health Networking, Applications and Services (Healthcom).

[78]  Sri Krishna,et al.  Supervised Machine Learning Approaches for Medical Data Set Classification-A Review , 2022 .

[79]  Muhammad Ghulam,et al.  Self-attention based recurrent convolutional neural network for disease prediction using healthcare data , 2019, Comput. Methods Programs Biomed..

[80]  Ioana Barbantan,et al.  Concept extraction from medical documents a contextual approach , 2015, 2015 IEEE International Conference on Intelligent Computer Communication and Processing (ICCP).

[81]  Jia Shi,et al.  DeepDiagnosis: DNN-Based Diagnosis Prediction from Pediatric Big Healthcare Data , 2018, 2018 Sixth International Conference on Advanced Cloud and Big Data (CBD).

[82]  Cheng-Sheng Yu,et al.  Development of an Online Health Care Assessment for Preventive Medicine: A Machine Learning Approach , 2020, Journal of medical Internet research.

[83]  Joshua C. Denny,et al.  Identifying lupus patients in electronic health records: Development and validation of machine learning algorithms and application of rule-based algorithms. , 2019, Seminars in arthritis and rheumatism.

[84]  E-Liang Chen,et al.  An automatic diagnostic system for CT liver image classification , 1998, IEEE Transactions on Biomedical Engineering.

[85]  Bram van Ginneken,et al.  Fast Convolutional Neural Network Training Using Selective Data Sampling: Application to Hemorrhage Detection in Color Fundus Images , 2016, IEEE Transactions on Medical Imaging.

[86]  Yongfeng Huang,et al.  Face recognition: A novel un-supervised convolutional neural network method , 2016, 2016 IEEE International Conference of Online Analysis and Computing Science (ICOACS).

[87]  Rob Stocker,et al.  Using Decision Tree for Diagnosing Heart Disease Patients , 2011, AusDM.

[88]  W. Geng,et al.  Model-based reasoning methods for diagnosis in integrative medicine based on electronic medical records and natural language processing , 2020, medRxiv.

[89]  Hongfang Liu,et al.  Modeling asynchronous event sequences with RNNs , 2018, J. Biomed. Informatics.

[90]  Qing Wang,et al.  Cataract Detection and Grading with Retinal Images Using SOM-RBF Neural Network , 2019, 2019 IEEE Symposium Series on Computational Intelligence (SSCI).

[91]  Miao Tian,et al.  Deep Belief Network Based on Double Weber Local Descriptor in Micro-expression Recognition , 2017, MUE/FutureTech.

[92]  Tien Yin Wong,et al.  Glaucoma detection based on deep convolutional neural network , 2015, 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[93]  D. Lynch,et al.  Pediatric diffuse lung disease: diagnosis and classification using high-resolution CT. , 1999, AJR. American journal of roentgenology.

[94]  Stephen Lin,et al.  DeepVessel: Retinal Vessel Segmentation via Deep Learning and Conditional Random Field , 2016, MICCAI.

[95]  Douglas H. Fernald,et al.  Electronic Health Record Challenges, Workarounds, and Solutions Observed in Practices Integrating Behavioral Health and Primary Care , 2015, The Journal of the American Board of Family Medicine.

[96]  Yuan Luo,et al.  Contralateral Breast Cancer Event Detection Using Nature Language Processing , 2017, AMIA.

[97]  Philippe Burlina,et al.  Detection of age-related macular degeneration via deep learning , 2016, 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI).

[98]  S. Mani,et al.  Extracting and integrating data from entire electronic health records for detecting colorectal cancer cases. , 2011, AMIA ... Annual Symposium proceedings. AMIA Symposium.

[99]  Charles A. Johnson,et al.  Patient-Centered Medicine: Transforming the Clinical Method , 1995 .

[100]  Khalid Masood Khan,et al.  Brain Tumor Analysis Empowered with Deep Learning: A Review, Taxonomy, and Future Challenges , 2020, Brain sciences.

[101]  John A. Quinn,et al.  Deep Convolutional Neural Networks for Microscopy-Based Point of Care Diagnostics , 2016, MLHC.

[102]  Noémie Elhadad,et al.  Multi-Label Classification of Patient Notes: Case Study on ICD Code Assignment , 2018, AAAI Workshops.

[103]  Javier Del Ser,et al.  Deep Learning for Multigrade Brain Tumor Classification in Smart Healthcare Systems: A Prospective Survey , 2020, IEEE Transactions on Neural Networks and Learning Systems.

[104]  Xiaoyu Li,et al.  Natural Language Processing for EHR-Based Computational Phenotyping , 2018, IEEE/ACM Transactions on Computational Biology and Bioinformatics.

[105]  Jason H. Moore,et al.  Learning classifier systems: a complete introduction, review, and roadmap , 2009 .

[106]  K Neil Jenkings,et al.  The challenge of electronic health records (EHRs) design and implementation: responses of health workers to drawing a 'big and rich picture' of a future EHR programme using animated tools. , 2007, Informatics in primary care.

[107]  Evgeniy Gabrilovich,et al.  A Review of Relational Machine Learning for Knowledge Graphs , 2015, Proceedings of the IEEE.

[108]  Shu Liao,et al.  Unsupervised Deep Feature Learning for Deformable Registration of MR Brain Images , 2013, MICCAI.

[109]  Régis Beuscart,et al.  Data Mining to Generate Adverse Drug Events Detection Rules , 2011, IEEE Transactions on Information Technology in Biomedicine.

[110]  Peter J. Haug,et al.  A natural language parsing system for encoding admitting diagnoses , 1997, AMIA.

[111]  J. Denny,et al.  Naïve Electronic Health Record phenotype identification for Rheumatoid arthritis. , 2011, AMIA ... Annual Symposium proceedings. AMIA Symposium.

[112]  Yongfeng Huang,et al.  Learning a Semantic Space for Modeling Images, Tags and Feelings in Cross-Media Search , 2019, PAKDD.

[113]  Wen-Lian Hsu,et al.  Coreference resolution of medical concepts in discharge summaries by exploiting contextual information , 2012, J. Am. Medical Informatics Assoc..

[114]  Daniel L. Rubin,et al.  Automated Grading of Gliomas using Deep Learning in Digital Pathology Images: A modular approach with ensemble of convolutional neural networks , 2015, AMIA.

[115]  Daniel Sonntag,et al.  Automatic Extraction of Breast Cancer Information from Clinical Reports , 2017, 2017 IEEE 30th International Symposium on Computer-Based Medical Systems (CBMS).

[116]  Xudong Zhang,et al.  Applying Support Vector Machine to Electronic Health Records for Cancer Classification , 2019, 2019 Spring Simulation Conference (SpringSim).

[117]  James M. Brown,et al.  Automated Diagnosis of Plus Disease in Retinopathy of Prematurity Using Deep Convolutional Neural Networks , 2018, JAMA ophthalmology.

[118]  Lei Wang,et al.  HEp-2 Cell Image Classification With Deep Convolutional Neural Networks , 2015, IEEE Journal of Biomedical and Health Informatics.

[119]  Meng Wang,et al.  Disease Inference from Health-Related Questions via Sparse Deep Learning , 2015, IEEE Transactions on Knowledge and Data Engineering.

[120]  Kemal Adem,et al.  Classification and diagnosis of cervical cancer with softmax classification with stacked autoencoder , 2019, Expert Syst. Appl..

[121]  Lan-Juan Li,et al.  Medical Aided Diagnosis Using Electronic Medical Records Based on LDA and Word Vector Model , 2017, 2017 4th International Conference on Information Science and Control Engineering (ICISCE).

[122]  Gautham Suresh,et al.  Patient Safety in the Context of Neonatal Intensive Care: Research and Educational Opportunities , 2011, Pediatric Research.

[123]  Jin Zhao,et al.  Discriminant deep belief network for high-resolution SAR image classification , 2017, Pattern Recognit..

[124]  K Akazawa,et al.  Accuracy in the Diagnostic Prediction of Acute Appendicitis Based on the Bayesian Network Model , 2007, Methods of Information in Medicine.

[125]  Shyam Visweswaran,et al.  The application of naive Bayes model averaging to predict Alzheimer's disease from genome-wide data , 2011, J. Am. Medical Informatics Assoc..

[126]  S Biafore,et al.  Predictive solutions bring more power to decision makers. , 1999, Health management technology.

[127]  Hang Chang,et al.  Unsupervised Transfer Learning via Multi-Scale Convolutional Sparse Coding for Biomedical Applications , 2018, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[128]  M. Shamim Hossain,et al.  Multiple Disease Risk Assessment With Uniform Model Based on Medical Clinical Notes , 2016, IEEE Access.

[129]  Huazhu Fu,et al.  Retinal vessel segmentation via deep learning network and fully-connected conditional random fields , 2016, 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI).

[130]  Subhashini Venugopalan,et al.  Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs. , 2016, JAMA.

[131]  Tran Manh Tuan,et al.  Dental Diagnosis from X-Ray Images using Fuzzy Rule-Based Systems , 2017, Int. J. Fuzzy Syst. Appl..

[132]  C. Kruse,et al.  Challenges and Opportunities of Big Data in Health Care: A Systematic Review , 2016, JMIR medical informatics.

[133]  S. Ajami,et al.  Barriers for Adopting Electronic Health Records (EHRs) by Physicians , 2013, Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH.

[134]  Jaume Bacardit,et al.  Functional Network Construction in Arabidopsis Using Rule-Based Machine Learning on Large-Scale Data Sets[C][W][OA] , 2011, Plant Cell.

[135]  Gregory Makoul,et al.  Research Paper: The Use of Electronic Medical Records: Communication Patterns in Outpatient Encounters , 2001, J. Am. Medical Informatics Assoc..

[136]  A. Lungu,et al.  Diagnosis of Pulmonary Hypertension from Magnetic Resonance Imaging–Based Computational Models and Decision Tree Analysis , 2016, Pulmonary circulation.

[137]  Nikos Komodakis,et al.  A Deep Metric for Multimodal Registration , 2016, MICCAI.

[138]  Hui Li,et al.  Predicting Clinical Visits Using Recurrent Neural Networks and Demographic Information , 2018, 2018 IEEE 22nd International Conference on Computer Supported Cooperative Work in Design ((CSCWD)).

[139]  Abdulhamit Subasi,et al.  Data Mining Techniques for Medical Data Classification , 2011 .

[140]  Thomas J. Watson,et al.  An empirical study of the naive Bayes classifier , 2001 .

[141]  Xiao Zeng,et al.  A WEB-Based Version of MedLEE: A Medical Language Extraction and Encoding System. , 1996 .

[142]  Heart Disease Prediction using Naive Bayes Classification in Data Mining , 2014 .

[143]  Sai-Ho Ling,et al.  An Efficient Diagnosis System for Parkinson's Disease Using Deep Belief Network , 2017 .

[144]  Max Welling,et al.  Auto-Encoding Variational Bayes , 2013, ICLR.

[145]  Madhu S. Nair,et al.  Computer-aided diagnosis of clinically significant prostate cancer from MRI images using sparse autoencoder and random forest classifier , 2018 .

[146]  M. Abràmoff,et al.  Improved Automated Detection of Diabetic Retinopathy on a Publicly Available Dataset Through Integration of Deep Learning. , 2016, Investigative ophthalmology & visual science.

[147]  Zahid Halim,et al.  Optimisation-based training of evolutionary convolution neural network for visual classification applications , 2020, IET Comput. Vis..

[148]  Yuan Luo,et al.  Deep Generative Classifiers for Thoracic Disease Diagnosis with Chest X-ray Images , 2018, 2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM).

[149]  Scott T. Weiss,et al.  Extracting principal diagnosis, co-morbidity and smoking status for asthma research: evaluation of a natural language processing system , 2006, BMC Medical Informatics Decis. Mak..

[150]  Junghui Chen,et al.  Image-Based Process Monitoring Using Deep Belief Networks , 2018 .

[151]  Yan Xu,et al.  Deep learning of feature representation with multiple instance learning for medical image analysis , 2014, 2014 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP).

[152]  Anthony N. Nguyen,et al.  Symbolic rule-based classification of lung cancer stages from free-text pathology reports , 2010, J. Am. Medical Informatics Assoc..

[153]  Vasudevan Jagannathan,et al.  Natural language processing framework to assess clinical conditions. , 2009, Journal of the American Medical Informatics Association : JAMIA.

[154]  Scott Shenker,et al.  Spark: Cluster Computing with Working Sets , 2010, HotCloud.

[155]  Jonathan Timmis,et al.  Artificial Immune Systems: A New Computational Intelligence Approach , 2003 .

[156]  Leilei Sun,et al.  A fusion framework to extract typical treatment patterns from electronic medical records , 2020, Artif. Intell. Medicine.

[157]  Azuraliza Abu Bakar,et al.  Medical data classification with Naive Bayes approach , 2012 .

[158]  Hosam F. El-Sofany,et al.  A Cloud-based Model for Medical Diagnosis using Fuzzy Logic Concepts , 2019, 2019 International Conference on Innovative Trends in Computer Engineering (ITCE).

[159]  Jianwei Leng,et al.  Performance of a Natural Language Processing (NLP) Tool to Extract Pulmonary Function Test (PFT) Reports from Structured and Semistructured Veteran Affairs (VA) Data , 2016, EGEMS.

[160]  Tao Chen,et al.  Refinery scheduling with varying crude: A deep belief network classification and multimodel approach , 2014 .

[161]  Fabio A. González,et al.  Automatic detection of invasive ductal carcinoma in whole slide images with convolutional neural networks , 2014, Medical Imaging.

[162]  Yongfeng Huang,et al.  Unsupervised pre-trained filter learning approach for efficient convolution neural network , 2019, Neurocomputing.

[163]  M. Taib,et al.  An Analysis of Image Enhancement Techniques for Dental X-ray Image Interpretation , 2012 .

[164]  Yash Raj Shrestha,et al.  A Deep Learning Pipeline for Patient Diagnosis Prediction Using Electronic Health Records , 2020, ArXiv.

[165]  Sungroh Yoon,et al.  Adversarial Training for Disease Prediction from Electronic Health Records with Missing Data , 2017 .