THE EFFECTS OF SUBFRACTURE IMPACT LOADING ON THE PATELLOFEMORAL JOINT IN A RABBIT MODEL

In this study it is shown that subfracture impact loading to a joint creates stresses in cartilage and bone which can initiate a chronic osteoarthrosis. The magnitude and location of the impact induced stresses are dependent on the orientation and the intensity of loading. Impact loading produced lesions on retro-patellar cartilage and their depths increased as the thickness of subchondral bone increased with time post-impact. Mechanical tests of cartilage indicated significant softening twelve months post-impact. These alterations are similar to those documented clinically as early OA (osteoarthrosis, osteoarthritis). In vitro impacts of isolated limbs, together with mathematical models, showed that high mean stress generated during impact may help protect joint tissues from acute injury. This study and other studies are used to develop stress-based tissue failure criteria for predicting an osteoarthrosis following subfracture impact loading. (A) For the covering abstract of the conference see IRRD 891635.

[1]  J L Lewis,et al.  An analytical model of joint contact. , 1990, Journal of biomechanical engineering.

[2]  E. Radin,et al.  Effects of mechanical loading on the tissues of the rabbit knee , 1984, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[3]  V. Mow,et al.  Biphasic indentation of articular cartilage--I. Theoretical analysis. , 1987, Journal of biomechanics.

[4]  R. Haut,et al.  Contact pressures in the patellofemoral joint during impact loading on the human flexed knee , 1989, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[5]  J H Siegel,et al.  Functional recovery and medical costs of trauma: an analysis by type and severity of injury. , 1988, The Journal of trauma.

[6]  R. Haut,et al.  An analytical model to study blunt impact response of the rabbit P-F joint. , 1995, Journal of biomechanical engineering.

[7]  T. Oegema,et al.  Subchondral damage after acute transarticular loading: An in vitro model of joint injury , 1992, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[8]  J Black,et al.  Mechanical behavior of articular cartilage quantitative changes with enzymatic alteration of the proteoglycan fraction. , 1987, Bulletin of the Hospital for Joint Diseases Orthopaedic Institute.

[9]  R M Rose,et al.  Effect of repetitive impulsive loading on the knee joints of rabbits. , 1978, Clinical orthopaedics and related research.

[10]  W. Bradley,et al.  Bone contusions of the knee: increased lesion detection with fast spin-echo MR imaging with spectroscopic fat saturation. , 1993, Radiology.

[11]  H J Helminen,et al.  Indentation stiffness of young canine knee articular cartilage--influence of strenuous joint loading. , 1990, Journal of biomechanics.

[12]  H. Matsui,et al.  Morphometric analysis of subchondral bone of the tibial condyle in osteoarthrosis. , 1993, Clinical orthopaedics and related research.

[13]  P. Rasmussen Tibial condylar fractures as a cause of degenerative arthritis. , 1972, Acta orthopaedica Scandinavica.

[14]  A. Vellet,et al.  Occult posttraumatic osteochondral lesions of the knee: prevalence, classification, and short-term sequelae evaluated with MR imaging. , 1991, Radiology.

[15]  L. Engebretsen,et al.  Osteochondral lesions and cruciate ligament injuries. MRI in 18 knees. , 1993, Acta orthopaedica Scandinavica.

[16]  P C Dischinger,et al.  Lower extremity injuries in drivers of airbag-equipped automobiles: clinical and crash reconstruction correlations. , 1995, The Journal of trauma.

[17]  R. Haut,et al.  Mechanical responses of the rabbit patello-femoral joint to blunt impact. , 1995, Journal of biomechanical engineering.

[18]  G. Chapchal Posttraumatic osteoarthritis after injury of the knee and hip joint. , 1978, Reconstruction surgery and traumatology.

[19]  A. Lund,et al.  Driver fatalities in 1985-1993 cars with airbags. , 1995, The Journal of trauma.

[20]  Patrick J. Atkinson,et al.  Insult to the Human Cadaver Patellofemoral Joint: Effects of Age on Fracture Tolerance and Occult Injury , 1995 .

[21]  I. Paul,et al.  Response of joints to impact loading. 3. Relationship between trabecular microfractures and cartilage degeneration. , 1973, Journal of biomechanics.

[22]  L. N. Blanco,et al.  Biomechanical and biochemical properties of dog cartilage in experimentally induced osteoarthritis. , 1984, Annals of the rheumatic diseases.

[23]  T. Oegema,et al.  The effects of indirect blunt trauma on adult canine articular cartilage. , 1983, The Journal of bone and joint surgery. American volume.

[24]  Patricia C. Dischinger,et al.  Lower extremity fractures in motor vehicle collisions: influence of direction of impact and seatbelt use , 1992 .

[25]  D C Viano,et al.  Restraint effectiveness, availability and use in fatal crashes: implications to injury control. , 1995, The Journal of trauma.

[26]  P. Atkinson,et al.  Subfracture insult to the human cadaver patellofemoral joint produces occult injury , 1995, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[27]  John D. States,et al.  Adult Occupant Injuries of the Lower Limb , 1986 .

[28]  W. Hayes,et al.  A mathematical analysis for indentation tests of articular cartilage. , 1972, Journal of biomechanics.