Pulsed electromagnetic fields stimulate osteogenic differentiation and maturation of osteoblasts by upregulating the expression of BMPRII localized at the base of primary cilium.
暂无分享,去创建一个
Hui-Ping Ma | Shaoke Li | C. Xian | Keming Chen | Jufang Wang | Yan-Fang Xie | Wen-Gui Shi | Jian Zhou | Yu-Hai Gao | Shao-Feng Li | Qing-Qing Fang | Ming-Gang Wang | Ju-Fang Wang | Cory J. Xian | Ke-Ming Chen | Jian Zhou | Wen-gui Shi | Qingqing Fang | Hui-Ping Ma | Ming-gang Wang | Yu‐Hai Gao | Yan-fang Xie | Yu-Hai Gao | Yu-Hai Gao
[1] Christopher R Jacobs,et al. Mechanical signals promote osteogenic fate through a primary cilia‐mediated mechanism , 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[2] D. Clapham,et al. Primary Cilia Are Not Calcium-Responsive Mechanosensors , 2016, Nature.
[3] K. Eckardt,et al. Anoctamin 6 is localized in the primary cilium of renal tubular cells and is involved in apoptosis-dependent cyst lumen formation , 2015, Cell Death and Disease.
[4] Huiyong Shen,et al. Imbalance Between Bone Morphogenetic Protein 2 and Noggin Induces Abnormal Osteogenic Differentiation of Mesenchymal Stem Cells in Ankylosing Spondylitis , 2015, Arthritis & rheumatology.
[5] H. M. Jamil,et al. TGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formation , 2015, Bone Research.
[6] C. Xian,et al. Pulsed electromagnetic fields promote osteoblast mineralization and maturation needing the existence of primary cilia , 2015, Molecular and Cellular Endocrinology.
[7] Y. Mishina,et al. PDGF-AA Promotes Osteogenic Differentiation and Migration of Mesenchymal Stem Cell by Down-Regulating PDGFRα and Derepressing BMP-Smad1/5/8 Signaling , 2014, PloS one.
[8] V. Shah,et al. PDGF receptor-α promotes TGF-β signaling in hepatic stellate cells via transcriptional and posttranscriptional regulation of TGF-β receptors. , 2014, American journal of physiology. Gastrointestinal and liver physiology.
[9] J. Helms,et al. The primary cilium as an integration center for Hedgehog and Wnt signalling , 2014 .
[10] Lei Ma,et al. Effects of PEMF exposure at different pulses on osteogenesis of MC3T3-E1 cells. , 2014, Archives of oral biology.
[11] C. Jacobs,et al. Oscillatory fluid flow influences primary cilia and microtubule mechanics , 2014, Cytoskeleton.
[12] Philippe Soriano,et al. PI3K-mediated PDGFRα signaling regulates survival and proliferation in skeletal development through p53-dependent intracellular pathways , 2014, Genes & development.
[13] Shun-Fu Chang,et al. Mechanical regulation of cancer cell apoptosis and autophagy: roles of bone morphogenetic protein receptor, Smad1/5, and p38 MAPK. , 2013, Biochimica et biophysica acta.
[14] W. Guo,et al. Pulsed Electromagnetic Fields Improve Bone Microstructure and Strength in Ovariectomized Rats through a Wnt/Lrp5/β-Catenin Signaling-Associated Mechanism , 2013, PloS one.
[15] J. Shah,et al. Cilioplasm is a cellular compartment for calcium signaling in response to mechanical and chemical stimuli , 2013, Cellular and Molecular Life Sciences.
[16] U. Wolfrum,et al. Septins 2, 7 and 9 and MAP4 colocalize along the axoneme in the primary cilium and control ciliary length , 2013, Journal of Cell Science.
[17] Elizabeth G. Loboa,et al. Primary Cilia: The Chemical Antenna Regulating Human Adipose-Derived Stem Cell Osteogenesis , 2013, PloS one.
[18] A. Schwab,et al. PDGFR&agr; signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2–ERK1/2–p90RSK and AKT signaling pathways , 2012, Journal of Cell Science.
[19] B. Ge,et al. Effect of 3.6-mT sinusoidal electromagnetic fields on proliferation and differentiation of osteoblasts in vitro. , 2012, Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae.
[20] Elizabeth L Adams,et al. Initiation of BMP2 signaling in domains on the plasma membrane , 2012, Journal of cellular physiology.
[21] C. Jacobs,et al. Mechanosensing by the Primary Cilium: Deletion of Kif3A Reduces Bone Formation Due to Loading , 2012, PloS one.
[22] K. Hankenson,et al. Integration of BMP, Wnt, and notch signaling pathways in osteoblast differentiation , 2011, Journal of cellular biochemistry.
[23] Keming Chen,et al. Sinusoidal electromagnetic field stimulates rat osteoblast differentiation and maturation via activation of NO-cGMP-PKG pathway. , 2011, Nitric oxide : biology and chemistry.
[24] C. Jacobs,et al. A role for the primary cilium in paracrine signaling between mechanically stimulated osteocytes and mesenchymal stem cells. , 2011, Biochemical and biophysical research communications.
[25] L. Bonewald,et al. Conditional deletion of Pkd1 in osteocytes disrupts skeletal mechanosensing in mice , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[26] Ron Y Kwon,et al. Primary cilium‐dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[27] Peter Satir,et al. The primary cilium at a glance , 2010, Journal of Cell Science.
[28] Jinghui Huang,et al. Circadian rhythm affects the preventive role of pulsed electromagnetic fields on ovariectomy-induced osteoporosis in rats. , 2010, Bone.
[29] S. Vukicevic,et al. Identification of a Key Residue Mediating Bone Morphogenetic Protein (BMP)-6 Resistance to Noggin Inhibition Allows for Engineered BMPs with Superior Agonist Activity* , 2010, The Journal of Biological Chemistry.
[30] N. Simmons,et al. The Pyrophosphate Transporter ANKH is Expressed in Kidney and Bone Cells and Colocalises to the Primary Cilium/Basal Body Complex , 2009, Cellular Physiology and Biochemistry.
[31] Madeline A Lancaster,et al. The primary cilium as a cellular signaling center: lessons from disease. , 2009, Current opinion in genetics & development.
[32] Richard H W Funk,et al. Electromagnetic effects - From cell biology to medicine. , 2009, Progress in histochemistry and cytochemistry.
[33] Tomokazu Fukuda,et al. BMP type I receptor inhibition reduces heterotopic ossification , 2008, Nature Medicine.
[34] N. LaRusso,et al. Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors. , 2008, American journal of physiology. Gastrointestinal and liver physiology.
[35] P. Satir. Primary cilia: Integral to development and disease , 2008, Developmental dynamics : an official publication of the American Association of Anatomists.
[36] Randall T Peterson,et al. Structure-activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors. , 2008, Bioorganic & medicinal chemistry letters.
[37] B. Magenheimer,et al. Polycystin-1 Regulates Skeletogenesis through Stimulation of the Osteoblast-specific Transcription Factor RUNX2-II* , 2008, Journal of Biological Chemistry.
[38] G. Bishop,et al. Bardet–Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia , 2008, Proceedings of the National Academy of Sciences.
[39] J. Cornish,et al. Imatinib Promotes Osteoblast Differentiation by Inhibiting PDGFR Signaling and Inhibits Osteoclastogenesis by Both Direct and Stromal Cell‐Dependent Mechanisms , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[40] Andrea Giustina,et al. Mechanisms of anabolic therapies for osteoporosis. , 2007, The New England journal of medicine.
[41] Ron Y Kwon,et al. Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism , 2007, Proceedings of the National Academy of Sciences.
[42] P. Ma,et al. Icariin inhibits the osteoclast formation induced by RANKL and macrophage-colony stimulating factor in mouse bone marrow culture. , 2007, Die Pharmazie.
[43] C. Tabin,et al. BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing , 2006, Nature Genetics.
[44] Y. Henis,et al. Different Routes of Bone Morphogenic Protein (BMP) Receptor Endocytosis Influence BMP Signaling , 2006, Molecular and Cellular Biology.
[45] Peter Satir,et al. PDGFRαα Signaling Is Regulated through the Primary Cilium in Fibroblasts , 2005, Current Biology.
[46] J. Gulcher,et al. Linkage of Osteoporosis to Chromosome 20p12 and Association to BMP2 , 2003, PLoS biology.
[47] P. Knaus,et al. Effect of the distribution and clustering of the type I A BMP receptor (ALK3) with the type II BMP receptor on the activation of signalling pathways , 2003, Journal of Cell Science.
[48] G. Pazour,et al. Chlamydomonas IFT88 and Its Mouse Homologue, Polycystic Kidney Disease Gene Tg737, Are Required for Assembly of Cilia and Flagella , 2000, The Journal of cell biology.
[49] L. Gilboa,et al. Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors. , 2000, Molecular biology of the cell.
[50] B. Hogan,et al. Bone morphogenetic proteins: multifunctional regulators of vertebrate development. , 1996, Genes & development.
[51] L. Larsen,et al. TGF-Signaling Is Associated with Endocytosis at the Pocket Region of the Primary Cilium , 2013 .
[52] J. Kanis,et al. Comparative cost-effectiveness of bazedoxifene and raloxifene in the treatment of postmenopausal osteoporosis in Europe, using the FRAX algorithm , 2013, Osteoporosis International.
[53] L. Larsen,et al. Using nucleofection of siRNA constructs for knockdown of primary cilia in P19.CL6 cancer stem cell differentiation into cardiomyocytes. , 2009, Methods in cell biology.
[54] K. Anderson,et al. The primary cilium as a Hedgehog signal transduction machine. , 2009, Methods in cell biology.
[55] P. Satir,et al. The primary cilium coordinates signaling pathways in cell cycle control and migration during development and tissue repair. , 2008, Current topics in developmental biology.
[56] Di Chen,et al. Growth Regulatory Factors and Bone , 2004, Reviews in Endocrine and Metabolic Disorders.
[57] R. Adkins,et al. The effect of pulsed electromagnetic fields on osteoporosis at the knee in individuals with spinal cord injury. , 1999, The journal of spinal cord medicine.
[58] F. Tábrah,et al. Clinical report on long-term bone density after short-term EMF application. , 1998, Bioelectromagnetics.