In vivo effects of Aloe arborescens Miller var. natalensis Berger (Kidachi aloe) on experimental tinea pedis in guinea‐pig feet

Trichophytosis was induced in guinea‐pigs and the antifungal effects of Aloe arborescens Miller var. natalensis Berger (Kidachi aloe) evaluated in comparison with lanoconazole, a commercially available antifungal agent. Trichophytosis was induced by inoculation of arthrospores of Trichophyton mentagrophytes cephalic strain SM‐110 (T. mentagrophytes SM‐110) onto the plantar part of guinea‐pig feet. Culture studies after application of 30% freeze‐dried Kidachi aloe for 10 days showed a 70% growth inhibition compared with the untreated animals.