Nicotinic Acetylcholine receptors: from molecular biology to cognition

number of sections on the problems seen with minimally invasive procedures. Whilst, again, these are, like the majority, well written and readable, much is repeated and is what one would again call ‘common sense’. This section, however, is saved by some excellent chapters documenting the difficult problems with the more unusual spinal conditions: neurofibromatosis, achondroplasia and myelomeningocele. This section also contained the best explanation of the aetiology and management of epidural fibrosis and arachnoiditis that I have ever come across. The fun is in the final section. Here, complication prevention is discussed. Much is made of optimum patient selection and rightly so. Again, statements and opinions are well argued and supported with evidence. There is a fascinating chapter on house staff to include a discussion on complication rate and changeover dates. I shall leave you to read the text to decide whether you have your operation in early August or February! Finally, there is the inevitable chapter on the legal implications of complications and strategies to help. I do feel this text is an excellent documentation of the strategy and knowledge required by a contemporary spinal surgeon or physician to minimize complications and their effects including legal redress. It is a readable, well-structured and ready source of well-researched data. I think it is an invaluable aid for guiding informed consent and, therefore, a wise purchase for any established or budding spinal surgeon.