Neuroblastoma in a pair of identical twins.

Hereditary neuroblastoma in a pair of identical twins is reported. In one of the twins the tumor occurred in fetal life and caused death of the twin before birth; in the other one, the tumor occurred at two months of life as IV-S neuroblastoma in the liver with primary tumor undetected. The unusual clinical course of the latter case is described: twice there was tumor regression, but in spite of treatment, fatal uncontrolled growth occurred. The family history, characterized by neoplasms of dissimilar cell types but without additional cases of neuroblastoma, is also detailed.

[1]  A. Evans,et al.  Do infants with stage IV-S neuroblastoma need treatment? , 1981, Archives of disease in childhood.

[2]  A. Knudson,et al.  Sounding board. Regression of neuroblastoma IV-S: a genetic hypothesis. , 1980, The New England journal of medicine.

[3]  A. Evans.  Staging and Treatment of Neuroblastoma , 1980, Cancer.

[4]  A. Evans,et al.  A review of 17 IV‐S neuroblastoma patients at the children's hospital of Philadelphia , 1980, Cancer.

[5]  J. Knight,et al.  Improved colorimetry of urinary 3-methoxy-4-hydroxyphenylacetic acid (homovanillic acid). , 1977, Clinical chemistry.

[6]  G. Morley.  ASBESTOS IN THE AIR , 1976, The Lancet.

[7]  C. Holton,et al.  Neuroblastoma in father and son. , 1976, JAMA.

[8]  C. Koop,et al.  Diagnosis and treatment of neuroblastoma. , 1976, Pediatric clinics of North America.

[9]  K. R. Lee,et al.  Familial neuroblastoma presenting as multiple tumors. , 1975, Radiology.

[10]  A. Knudson,et al.  Mutation and cancer: neuroblastoma and pheochromocytoma. , 1972, American journal of human genetics.

[11]  L. Helson.  Regression of neuroblastomas. , 1971, Lancet.

[12]  A. Evans,et al.  A proposed staging for children with neuroblastoma. Children's cancer study group A , 1971, Cancer.

[13]  A. Rausen,et al.  Diagnosis of neuroblastoma by qualitative and quantitative determination of catecholamine metabolites in urine , 1970, Cancer.

[14]  J. Fraumeni,et al.  Neuroblastoma: epidemiologic approach to its origin. , 1968, American journal of diseases of children.

[15]  D. Peterson.  The epidemiology of neuroblastoma. , 1968, Journal of pediatric surgery.

[16]  W. Cochran.  Neuroblastoma (Sympathicoblastoma) in Northern Ireland: A Review over a Ten-year Period , 1963 .

[17]  H. Stadler,et al.  Neuroblastomatosis in one of monozygotic twins. , 1955, The Journal of pediatrics.

[18]  H. Charache.  Neuroblastoma: a report of ten cases and review of the literature. , 1954, American journal of surgery.

[19]  Lee Cm.  The surgical significance of tumors in identical twins; a short review of the literature and a report of sympathicoblastoma occurring in monozygotic twins. , 1953 .

[20]  H. Brody.  Congenital malignant neuroblastoma of the suprarenal gland in one of twin girls. , 1950, American journal of human genetics.

[21]  L. Leape,et al.  Multifocal nondisseminated neuroblastoma. Report of two cases in siblings. , 1978, The Journal of pediatrics.

[22]  R. W. Miller.  Deaths from childhood leukemia and solid tumors among twins and other sibs in the United States, 1960-67. , 1971, Journal of the National Cancer Institute.

[23]  A. Barrett,et al.  Sympathicoblastoma: radiological findings in forty-three cases. , 1963, Clinical radiology.