Preferential location of lidocaine and etidocaine in lecithin bilayers as determined by EPR, fluorescence and 2H NMR.
暂无分享,去创建一个
[1] G. Strichartz,et al. Tetracaine-membrane interactions: effects of lipid composition and phase on drug partitioning, location, and ionization. , 2007, Biophysical journal.
[2] M. Skaf,et al. Interactions of chlorpromazine with phospholipid monolayers: effects of the ionization state of the drug. , 2007, Biophysical chemistry.
[3] A. Lyubartsev,et al. Dynamical and structural properties of charged and uncharged lidocaine in a lipid bilayer. , 2007, Biophysical chemistry.
[4] P. Pascutti,et al. Water solvent and local anesthetics: a computational study , 2007 .
[5] S. Oyama,et al. Interaction of local anesthetics with a peptide encompassing the IV/S4-S5 linker of the Na+ channel. , 2006, Biophysical chemistry.
[6] M. Skaf,et al. Molecular dynamics simulations of neutral chlorpromazine in zwitterionic phospholipid monolayers. , 2006, The journal of physical chemistry. B.
[7] Leonardo Fernandes Fraceto,et al. Interacao de anestesicos locais com lipossomos determinada por espectroscopia de infravermelho , 2006 .
[8] A. Spisni,et al. Differential effects of uncharged aminoamide local anesthetics on phospholipid bilayers, as monitored by 1H-NMR measurements. , 2005, Biophysical chemistry.
[9] L. Franzoni,et al. Spectroscopic evidence for a preferential location of lidocaine inside phospholipid bilayers. , 2002, Biophysical chemistry.
[10] W. G. Wood,et al. Amphiphilic effects of local anesthetics on rotational mobility in neuronal and model membranes. , 2002, Biochimica et biophysica acta.
[11] D. Yokaichiya,et al. Interaction of benzocaine with model membranes. , 2000, Biophysical chemistry.
[12] W. Catterall,et al. Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[13] S. Schreier,et al. Molecular and physicochemical aspects of local anesthetic-membrane interaction. , 1996, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
[14] S. Schreier,et al. Use of a novel method for determination of partition coefficients to compare the effect of local anesthetics on membrane structure. , 1995, Biochimica et biophysica acta.
[15] J. Baber,et al. Distribution of general anesthetics in phospholipid bilayers determined using 2H NMR and 1H-1H NOE spectroscopy. , 1995, Biochemistry.
[16] W. Catterall,et al. Molecular determinants of state-dependent block of Na+ channels by local anesthetics. , 1994, Science.
[17] H. Kamaya,et al. Local anesthetics destabilize lipid membranes by breaking hydration shell: infrared and calorimetry studies. , 1994, Biochimica et biophysica acta.
[18] S. P. Gupta,et al. QSAR (quantitative structure-activity relationship) studies on local anesthetics , 1991 .
[19] A. Jonas,et al. Pressure effects on dipalmitoylphosphatidylcholine bilayers measured by deuterium nuclear magnetic resonance , 1991 .
[20] S. Schreier,et al. Methods for the determination of partition coefficients based on the effect of solutes upon membrane structure , 1990 .
[21] D. Cafiso,et al. Localizing the nitroxide group of fatty acid and voltage-sensitive spin-labels in phospholipid bilayers. , 1988, Biochimica et biophysica acta.
[22] S. Schreier,et al. Spin label study of local anesthetic-lipid membrane interactions. Phase separation of the uncharged form and bilayer micellization by the charged form of tetracaine. , 1986, Biochimica et biophysica acta.
[23] R. Chatelier,et al. Effects of quenching mechanism and type of quencher association on stern-volmer plots in compartmentalized systems. , 1986, Biophysical journal.
[24] H. Jarrell,et al. Interaction of amphotericin B with membrane lipids as viewed by 2H-NMR. , 1984, Biochimica et biophysica acta.
[25] K. Kitamura,et al. Intra- and intermolecular proton-proton nuclear Overhauser effect studies on the interactions of chlorpromazine with lecithin vesicles , 1984 .
[26] I. Smith,et al. Anesthetic-membrane interaction: a 2H nuclear magnetic resonance study of the binding of specifically deuterated tetracaine and procaine to phosphatidylcholine. , 1984, Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire.
[27] S. Schreier,et al. Effect of lipid membranes on the apparent pK of the local anesthetic tetracaine. Spin label and titration studies. , 1984, Biochimica et biophysica acta.
[28] K. Sikaris,et al. The interaction of local anaesthetics with synthetic phospholipid bilayers. , 1982, Biochemical pharmacology.
[29] J. Westman,et al. Charge and pH dependent drug binding to model membranes. A 2H-NMR and light absorption study. , 1982, Biochimica et biophysica acta.
[30] M. Iwaki,et al. Fluidity of human erythrocyte membrane and effect of chlorpromazine on fluidity and phase separation of membrane. , 1981, Biochimica et biophysica acta.
[31] S. Schreier,et al. Molecular details of anesthetic--lipid interaction as seen by deuterium and phosphorus-31 nuclear magnetic resonance. , 1981, Biochemistry.
[32] M. Bloom,et al. Direct determination of the oriented sample nmr spectrum from the powder spectrum for systems with local axial symmetry , 1981 .
[33] S. Schreier,et al. Multiple binding sites for local anesthetics in membranes: characterization of the sites and their equilibria by deuterium NMR of specifically deuterated procaine and tetracaine. , 1980, Canadian journal of biochemistry.
[34] M. Rance,et al. Orientational order of unsaturated lipids in the membranes of Acholeplasma laidlawii as observed by 2H-NMR. , 1980, Biochimica et biophysica acta.
[35] H. Möhwald,et al. Monitoring the location profile of fluorophores in phosphatidylcholine bilayers by the use or paramagnetic quenching. , 1979, Biochimica et biophysica acta.
[36] J. Seelig. Deuterium magnetic resonance: theory and application to lipid membranes , 1977, Quarterly Reviews of Biophysics.
[37] B. Hille,et al. Local anesthetics: hydrophilic and hydrophobic pathways for the drug- receptor reaction , 1977, The Journal of general physiology.
[38] M. Bloom,et al. Quadrupolar echo deuteron magnetic resonance spectroscopy in ordered hydrocarbon chains , 1976 .
[39] B. Covino,et al. Local anesthetics : mechanisms of action and clinical use , 1976 .
[40] J. Seelig,et al. Bilayers of dipalmitoyl-3-sn-phosphatidylcholine. Conformational differences between the fatty acyl chains. , 1975, Biochimica et biophysica acta.
[41] G. Giotta,et al. Binding of spin-labeled local anesthetics to phosphatidylcholine and phosphatidylserine liposomes. , 1974, Archives of biochemistry and biophysics.
[42] P. E. Godici,et al. The dynamic structure of lipid membranes. A 13C nuclear magnetic resonance study using spin labels. , 1974, Biochemistry.
[43] G. Strichartz,et al. The Inhibition of Sodium Currents in Myelinated Nerve by Quaternary Derivatives of Lidocaine , 1973, The Journal of general physiology.
[44] G. Giotta,et al. Spin-labeled analogs of local anesthetics. , 1973, Journal of medicinal chemistry.
[45] L. Burnett,et al. Deuteron Quadrupole Coupling Constants in Three Solid Deuterated Paraffin Hydrocarbons: C2D6, C4D10, C6D14 , 1971 .