The RSC chromatin-remodeling complex influences mitotic exit and adaptation to the spindle assembly checkpoint by controlling the Cdc14 phosphatase

Rsc2 promotes Cdc14 release from the nucleolus to free cells from mitotic arrest.

[1]  R. Margolis,et al.  Substrate degradation by the anaphase promoting complex occurs during mitotic slippage. , 2010, Cell cycle.

[2]  K. Oegema,et al.  Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells. , 2010, Genes & development.

[3]  P. Plevani,et al.  Elevated Levels of the Polo Kinase Cdc5 Override the Mec1/ATR Checkpoint in Budding Yeast by Acting at Different Steps of the Signaling Pathway , 2010, PLoS genetics.

[4]  T. Mitchison,et al.  Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly. , 2009, Cancer cell.

[5]  Yanchang Wang,et al.  The molecular function of the yeast polo-like kinase Cdc5 in Cdc14 release during early anaphase. , 2009, Molecular biology of the cell.

[6]  H. Madhani,et al.  Nonredundant Requirement for Multiple Histone Modifications for the Early Anaphase Release of the Mitotic Exit Regulator Cdc14 from Nucleolar Chromatin , 2009, PLoS genetics.

[7]  M. Weinreich,et al.  Cdc7p-Dbf4p Regulates Mitotic Exit by Inhibiting Polo Kinase , 2009, PLoS genetics.

[8]  T. Itoh,et al.  Budding Yeast Wpl1(Rad61)-Pds5 Complex Counteracts Sister Chromatid Cohesion-Establishing Reaction , 2009, Current Biology.

[9]  J. Peters,et al.  The cohesin complex and its roles in chromosome biology. , 2008, Genes & development.

[10]  Angelika Amon,et al.  The Polo-like kinase Cdc5 interacts with FEAR network components and Cdc14 , 2008, Cell cycle.

[11]  F. Uhlmann,et al.  Separase cooperates with Zds1 and Zds2 to activate Cdc14 phosphatase in early anaphase , 2008, The Journal of cell biology.

[12]  Stephen S. Taylor,et al.  Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs. , 2008, Cancer cell.

[13]  B. Cairns,et al.  RSC regulates nucleosome positioning at Pol II genes and density at Pol III genes , 2008, The EMBO journal.

[14]  Jennifer L. Snead,et al.  A coupled chemical-genetic and bioinformatic approach to Polo-like kinase pathway exploration. , 2007, Chemistry & biology.

[15]  B. Delaval,et al.  Chromatin remodeling proteins interact with pericentrin to regulate centrosome integrity. , 2007, Molecular biology of the cell.

[16]  E. Salmon,et al.  The spindle-assembly checkpoint in space and time , 2007, Nature Reviews Molecular Cell Biology.

[17]  J. Peters.  The anaphase promoting complex/cyclosome: a machine designed to destroy , 2006, Nature Reviews Molecular Cell Biology.

[18]  Conly L. Rieder,et al.  Mitotic Checkpoint Slippage in Humans Occurs via Cyclin B Destruction in the Presence of an Active Checkpoint , 2006, Current Biology.

[19]  Bela Novak,et al.  Downregulation of PP2ACdc55 Phosphatase by Separase Initiates Mitotic Exit in Budding Yeast , 2006, Cell.

[20]  Elena Chiroli,et al.  The spindle position checkpoint in budding yeast: the motherly care of MEN , 2006, Cell Division.

[21]  M. Gartenberg,et al.  Targeting of cohesin by transcriptionally silent chromatin. , 2005, Genes & development.

[22]  Angelika Amon,et al.  Closing mitosis: the functions of the Cdc14 phosphatase and its regulation. , 2004, Annual review of genetics.

[23]  Helder Maiato,et al.  Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint. , 2004, Developmental cell.

[24]  Steven A. Carr,et al.  Phosphorylation by Cyclin B-Cdk Underlies Release of Mitotic Exit Activator Cdc14 from the Nucleolus , 2004, Science.

[25]  A. Shevchenko,et al.  Adaptation of a DNA Replication Checkpoint Response Depends upon Inactivation of Claspin by the Polo-like Kinase , 2004, Cell.

[26]  Jian Huang,et al.  A Role for the RSC Chromatin Remodeler in Regulating Cohesion of Sister Chromatid Arms , 2004, Cell cycle.

[27]  Angelika Amon,et al.  The Replication Fork Block Protein Fob1 Functions as a Negative Regulator of the FEAR Network , 2004, Current Biology.

[28]  A. Emili,et al.  The ctf13-30/CTF13 Genomic Haploinsufficiency Modifier Screen Identifies the Yeast Chromatin Remodeling Complex RSC, Which Is Required for the Establishment of Sister Chromatid Cohesion , 2004, Molecular and Cellular Biology.

[29]  F. Stegmeier,et al.  The role of the polo kinase Cdc5 in controlling Cdc14 localization. , 2003, Molecular biology of the cell.

[30]  Michael B. Yaffe,et al.  The Molecular Basis for Phosphodependent Substrate Targeting and Regulation of Plks by the Polo-Box Domain , 2003, Cell.

[31]  D. Moazed,et al.  Association of the RENT complex with nontranscribed and coding regions of rDNA and a regional requirement for the replication fork block protein Fob1 in rDNA silencing. , 2003, Genes & development.

[32]  Katsuhiko Shirahige,et al.  S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex , 2003, Nature.

[33]  D. Garza,et al.  Mutations in the yeast cyclin-dependent kinase Cdc28 reveal a role in the spindle assembly checkpoint , 2003, Molecular Genetics and Genomics.

[34]  P. Meluh,et al.  The Yeast RSC Chromatin-Remodeling Complex Is Required for Kinetochore Function in Chromosome Segregation , 2003, Molecular and Cellular Biology.

[35]  G. Lucchini,et al.  Budding yeast PAK kinases regulate mitotic exit by two different mechanisms , 2003, The Journal of cell biology.

[36]  P. Nurse,et al.  Function of Cdc2p‐dependent Bub1p phosphorylation and Bub1p kinase activity in the mitotic and meiotic spindle checkpoint , 2003, The EMBO journal.

[37]  Michael B Yaffe,et al.  Proteomic Screen Finds pSer/pThr-Binding Domain Localizing Plk1 to Mitotic Substrates , 2003, Science.

[38]  R. Haberman,et al.  Regulation of gene expression in adeno-associated virus vectors in the brain. , 2002, Methods.

[39]  Kim Nasmyth,et al.  Segregating Sister Genomes: The Molecular Biology of Chromosome Separation , 2002, Science.

[40]  A. Toh-E,et al.  Budding yeast Cdc5 phosphorylates Net1 and assists Cdc14 release from the nucleolus. , 2002, Biochemical and biophysical research communications.

[41]  J. Murray,et al.  RSC2, Encoding a Component of the RSC Nucleosome Remodeling Complex, Is Essential for 2μm Plasmid Maintenance in Saccharomyces cerevisiae , 2002, Molecular and Cellular Biology.

[42]  Roland S Annan,et al.  Cdc5 influences phosphorylation of Net1 and disassembly of the RENT complex , 2002, BMC Molecular Biology.

[43]  Kevin Struhl,et al.  Genome-wide location and regulated recruitment of the RSC nucleosome-remodeling complex. , 2002, Genes & development.

[44]  Angelika Amon,et al.  Separase, Polo Kinase, the Kinetochore Protein Slk19, and Spo12 Function in a Network that Controls Cdc14 Localization during Early Anaphase , 2002, Cell.

[45]  E. Salmon,et al.  Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation , 2001, The Journal of cell biology.

[46]  G. Lucchini,et al.  Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores , 2001, The EMBO journal.

[47]  R. Karess,et al.  Kinetochore dynein: its dynamics and role in the transport of the Rough deal checkpoint protein , 2001, Nature Cell Biology.

[48]  G. Lucchini,et al.  Role of the kinetochore protein Ndc10 in mitotic checkpoint activation in Saccharomyces cerevisiae , 2001, Molecular Genetics and Genomics.

[49]  D. Moazed,et al.  Net1 stimulates RNA polymerase I transcription and regulates nucleolar structure independently of controlling mitotic exit. , 2001, Molecular cell.

[50]  F. Uhlmann.  Secured cutting: controlling separase at the metaphase to anaphase transition , 2001, EMBO reports.

[51]  Karl Mechtler,et al.  Phosphorylation of the Cohesin Subunit Scc1 by Polo/Cdc5 Kinase Regulates Sister Chromatid Separation in Yeast , 2001, Cell.

[52]  Andrew W. Murray,et al.  Cdc28 Activates Exit from Mitosis in Budding Yeast , 2000, The Journal of cell biology.

[53]  D. Brady,et al.  Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function , 2000, Current Biology.

[54]  Kyung S. Lee,et al.  Essential Function of the Polo Box of Cdc5 in Subcellular Localization and Induction of Cytokinetic Structures , 2000, Molecular and Cellular Biology.

[55]  B. Cairns,et al.  Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. , 1999, Molecular cell.

[56]  K. Siegers,et al.  Epitope tagging of yeast genes using a PCR‐based strategy: more tags and improved practical routines , 1999, Yeast.

[57]  Giovanna Lucchini,et al.  Budding Yeast Bub2 Is Localized at Spindle Pole Bodies and Activates the Mitotic Checkpoint via a Different Pathway from Mad2 , 1999, The Journal of cell biology.

[58]  Rong Li,et al.  Bifurcation of the mitotic checkpoint pathway in budding yeast. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[59]  Anna Shevchenko,et al.  Exit from Mitosis Is Triggered by Tem1-Dependent Release of the Protein Phosphatase Cdc14 from Nucleolar RENT Complex , 1999, Cell.

[60]  M. Tyers,et al.  The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation. , 1998, Molecular cell.

[61]  A. Murray,et al.  Budding yeast Cdc20: a target of the spindle checkpoint. , 1998, Science.

[62]  K. Nasmyth,et al.  Cohesins: Chromosomal Proteins that Prevent Premature Separation of Sister Chromatids , 1997, Cell.

[63]  B. Cairns,et al.  Sfh1p, a component of a novel chromatin-remodeling complex, is required for cell cycle progression , 1997, Molecular and cellular biology.

[64]  X. Li,et al.  Inactivation of the cyclin-dependent kinase Cdc28 abrogates cell cycle arrest induced by DNA damage and disassembly of mitotic spindles in Saccharomyces cerevisiae , 1997, Molecular and cellular biology.

[65]  Andrew W. Murray,et al.  Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast , 1996, Current Biology.

[66]  A. Murray,et al.  Activation of the Budding Yeast Spindle Assembly Checkpoint Without Mitotic Spindle Disruption , 1996, Science.

[67]  P. Philippsen,et al.  New heterologous modules for classical or PCR‐based gene disruptions in Saccharomyces cerevisiae , 1994, Yeast.

[68]  Kim Nasmyth,et al.  The B-type cyclin kinase inhibitor p40 SIC1 controls the G1 to S transition in S. cerevisiae , 1994, Cell.

[69]  K Nasmyth,et al.  Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast. , 1993, The EMBO journal.

[70]  M. Mendenhall,et al.  An inhibitor of p34CDC28 protein kinase activity from Saccharomyces cerevisiae. , 1993, Science.

[71]  K. Loo,et al.  Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly , 1992, The Journal of cell biology.

[72]  C. Chahwan,et al.  Putting the brake on FEAR: Tof2 promotes the biphasic release of Cdc14 phosphatase during mitotic exit. , 2009, Molecular biology of the cell.

[73]  M. Snyder,et al.  Insertional mutagenesis: transposon-insertion libraries as mutagens in yeast. , 2002, Methods in enzymology.

[74]  G. Lucchini,et al.  Budding Yeast Bub 2 Is Localized at Spindle Pole Bodies and Activates the Mitotic Checkpoint via a Different Pathway from Mad 2 , 1999 .

[75]  Article number: 2005.0026 , 2022 .