Infant hospitalisations and fatalities averted by the maternal pertussis vaccination programme in England, 2012-2017: Post-implementation economic evaluation.

In October 2012, a maternal pertussis vaccination programme was implemented in England following an increased incidence and mortality in infants. We evaluated the cost-effectiveness of the programme by comparing pertussis-related infant hospitalisations and deaths in 2012-2017 with non-vaccination scenarios. Despite considerable uncertainties, findings support the cost-effectiveness of the programme.

[1]  M. Edelstein,et al.  Predictors of coverage of the national maternal pertussis and infant rotavirus vaccination programmes in England , 2017, Epidemiology and Infection.

[2]  S. Ladhani,et al.  Maternal vaccination against pertussis: a systematic review of the recent literature , 2017, Archives of Disease in Childhood: Fetal and Neonatal Edition.

[3]  N. Andrews,et al.  Sustained Effectiveness of the Maternal Pertussis Immunization Program in England 3 Years Following Introduction , 2016, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[4]  E. Miller,et al.  Investigating the pertussis resurgence in England and Wales, and options for future control , 2016, BMC Medicine.

[5]  N. Andrews,et al.  Cost-effectiveness and programmatic benefits of maternal vaccination against pertussis in England. , 2016, The Journal of infection.

[6]  N. Andrews,et al.  A case-control study to estimate the effectiveness of maternal pertussis vaccination in protecting newborn infants in England and Wales, 2012-2013. , 2015, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[7]  P. Beutels,et al.  Economic evaluations of implemented vaccination programmes: key methodological challenges in retrospective analyses. , 2014, Vaccine.

[8]  N. Andrews,et al.  Accelerating Control of Pertussis in England and Wales , 2012, Emerging infectious diseases.

[9]  J. Brazier,et al.  Populating an economic model with health state utility values: moving toward better practice. , 2010, Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.

[10]  E. Segedin,et al.  Pertussis requiring intensive care , 2007, Archives of Disease in Childhood.

[11]  A. B. Prasad,et al.  British National Formulary , 1994 .