Predicate-Based Focus-and-Context Visualization for 3D Ultrasound

Direct volume visualization techniques offer powerful insight into volumetric medical images and are part of the clinical routine for many applications. Up to now, however, their use is mostly limited to tomographic imaging modalities such as CT or MRI. With very few exceptions, such as fetal ultrasound, classic volume rendering using one-dimensional intensity-based transfer functions fails to yield satisfying results in case of ultrasound volumes. This is particularly due its gradient-like nature, a high amount of noise and speckle, and the fact that individual tissue types are rather characterized by a similar texture than by similar intensity values. Therefore, clinicians still prefer to look at 2D slices extracted from the ultrasound volume. In this work, we present an entirely novel approach to the classification and compositing stage of the volume rendering pipeline, specifically designed for use with ultrasonic images. We introduce point predicates as a generic formulation for integrating the evaluation of not only low-level information like local intensity or gradient, but also of high-level information, such as non-local image features or even anatomical models. Thus, we can successfully filter clinically relevant from non-relevant information. In order to effectively reduce the potentially high dimensionality of the predicate configuration space, we propose the predicate histogram as an intuitive user interface. This is augmented by a scribble technique to provide a comfortable metaphor for selecting predicates of interest. Assigning importance factors to the predicates allows for focus-and-context visualization that ensures to always show important (focus) regions of the data while maintaining as much context information as possible. Our method naturally integrates into standard ray casting algorithms and yields superior results in comparison to traditional methods in terms of visualizing a specific target anatomy in ultrasound volumes.

[1]  Silvia Born,et al.  Visual Analysis of Cardiac 4D MRI Blood Flow Using Line Predicates , 2013, IEEE Transactions on Visualization and Computer Graphics.

[2]  Anna Vilanova,et al.  Visualization of boundaries in volumetric data sets using LH histograms , 2006, IEEE Transactions on Visualization and Computer Graphics.

[3]  Hans-Peter Meinzer,et al.  Statistical shape models for 3D medical image segmentation: A review , 2009, Medical Image Anal..

[4]  Jörg-Stefan Praßni,et al.  Shape-based transfer functions for volume visualization , 2010, 2010 IEEE Pacific Visualization Symposium (PacificVis).

[5]  Bernhard Preim,et al.  Semi-Automatic Vortex Extraction in 4D PC-MRI Cardiac Blood Flow Data using Line Predicates , 2013, IEEE Transactions on Visualization and Computer Graphics.

[6]  Jesus J. Caban,et al.  Multi-dimensional transfer functions for effective visualization of streaming ultrasound and elasticity images , 2011, Medical Imaging.

[7]  Kwan-Liu Ma,et al.  A novel interface for higher-dimensional classification of volume data , 2003, IEEE Visualization, 2003. VIS 2003..

[8]  Carla Maria Dal Sasso Freitas,et al.  Importance-Aware Composition for Illustrative Volume Rendering , 2010, 2010 23rd SIBGRAPI Conference on Graphics, Patterns and Images.

[9]  Dani Lischinski,et al.  Variational classification for visualization of 3D ultrasound data , 2001, Proceedings Visualization, 2001. VIS '01..

[10]  Jörg-Stefan Praßni,et al.  Stroke-Based Transfer Function Design , 2008, VG/PBG@SIGGRAPH.

[11]  Yong Wan,et al.  Fast Volumetric Data Exploration with Importance-Based Accumulated Transparency Modulation , 2010, VG@Eurographics.

[12]  Nassir Navab,et al.  A Quadratic Energy Minimization Framework for Signal Loss Estimation from Arbitrarily Sampled Ultrasound Data , 2014, MICCAI.

[13]  Jens Schneider,et al.  ClearView: An Interactive Context Preserving Hotspot Visualization Technique , 2006, IEEE Transactions on Visualization and Computer Graphics.

[14]  Nassir Navab,et al.  Orientation-Driven Ultrasound Compounding Using Uncertainty Information , 2014, IPCAI.

[15]  Elsa D. Angelini,et al.  Surface Function Actives , 2009, J. Vis. Commun. Image Represent..

[16]  Stefan Bruckner,et al.  Illustrative Context-Preserving Volume Rendering , 2005, EuroVis.

[17]  Richard Szeliski,et al.  Computer Vision - Algorithms and Applications , 2011, Texts in Computer Science.

[18]  Bernhard Preim,et al.  Visual Computing for Medicine: Theory, Algorithms, and Applications , 2007 .

[19]  Christof Rezk-Salama,et al.  High-Level User Interfaces for Transfer Function Design with Semantics , 2006, IEEE Transactions on Visualization and Computer Graphics.

[20]  Nassir Navab,et al.  Ultrasound confidence maps using random walks , 2012, Medical Image Anal..

[21]  Joe Michael Kniss,et al.  Multidimensional Transfer Functions for Interactive Volume Rendering , 2002, IEEE Trans. Vis. Comput. Graph..

[22]  Georgios Sakas,et al.  Preprocessing and volume rendering of 3D ultrasonic data , 1995, IEEE Computer Graphics and Applications.

[23]  Xin Zhao,et al.  Modified Dendrogram of Attribute Space for Multidimensional Transfer Function Design , 2012, IEEE Transactions on Visualization and Computer Graphics.

[24]  Joerg Meyer,et al.  Pathline predicates and unsteady flow structures , 2008, The Visual Computer.

[25]  Stefan Bruckner,et al.  Eurographics/ Ieee-vgtc Symposium on Visualization 2008 Interaction-dependent Semantics for Illustrative Volume Rendering , 2022 .

[26]  Elsa D. Angelini,et al.  Brushlet segmentation for automatic detection of lumen borders in IVUS images: A comparison study , 2012, 2012 9th IEEE International Symposium on Biomedical Imaging (ISBI).

[27]  Alejandro F. Frangi,et al.  Muliscale Vessel Enhancement Filtering , 1998, MICCAI.