论文信息 - Linking H1 with chromatin and growth control

Linking H1 with chromatin and growth control

ABSTRACT The retinoblastoma protein (pRb) is considered to be one of the key regulators of cell proliferation. Here we describe our recent findings that linker histone H1.2 is an interaction partner for pRb and impacts upon the genome-wide chromatin binding properties of pRb. Consequently, H1.2 influences transcriptional repression and cell cycle control.

N. L. La Thangue | S. Munro

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