Does the BAFF dysregulation play a major role in the pathogenesis of systemic lupus erythematosus?

[1]  M. Gershwin,et al.  Integrating immunity: the immunculus and self-reactivity. , 2008, Journal of autoimmunity.

[2]  K. Tsuneyama,et al.  Monosodium glutamate (MSG): a villain and promoter of liver inflammation and dysplasia. , 2008, Journal of autoimmunity.

[3]  M. Blank,et al.  Autoimmunity: from the mosaic to the kaleidoscope. , 2008, Journal of autoimmunity.

[4]  S. Gay,et al.  Epigenetic clues to rheumatoid arthritis. , 2008, Journal of autoimmunity.

[5]  P. Arosio,et al.  New functions for an iron storage protein: the role of ferritin in immunity and autoimmunity. , 2008, Journal of autoimmunity.

[6]  I. Mackay,et al.  Cell damage and autoimmunity: a critical appraisal. , 2008, Journal of autoimmunity.

[7]  J. Pers,et al.  BAFF, APRIL, TWE-PRIL: who's who? , 2008, Autoimmunity reviews.

[8]  Y. Shoenfeld,et al.  The curiously suspicious: infectious disease may ameliorate an ongoing autoimmune destruction in systemic lupus erythematosus patients. , 2008, Journal of autoimmunity.

[9]  C. Kallenberg,et al.  Pathogenesis of PR3-ANCA associated vasculitis. , 2008, Journal of autoimmunity.

[10]  E. Jacobson,et al.  The HLA gene complex in thyroid autoimmunity: from epidemiology to etiology. , 2008, Journal of autoimmunity.

[11]  David E. Anderson,et al.  In vitro induction of regulatory T cells by anti-CD3 antibody in humans. , 2008, Journal of autoimmunity.

[12]  A. Tincani,et al.  Antinucleosome antibodies in primary antiphospholipid syndrome: a hint at systemic autoimmunity? , 2008, Journal of autoimmunity.

[13]  S. Shinton,et al.  Autoreactive B-1 B cells: constraints on natural autoantibody B cell antigen receptors. , 2007, Journal of autoimmunity.

[14]  W. Paul,et al.  Repertoire-dependent immunopathology. , 2007, Journal of autoimmunity.

[15]  I. Sanz,et al.  Delayed memory B cell recovery in peripheral blood and lymphoid tissue in systemic lupus erythematosus after B cell depletion therapy. , 2007, Arthritis and rheumatism.

[16]  C. Mackay,et al.  BAFF and MyD88 signals promote a lupuslike disease independent of T cells , 2007, The Journal of experimental medicine.

[17]  J. Pers,et al.  BAFF-modulated repopulation of B lymphocytes in the blood and salivary glands of rituximab-treated patients with Sjögren's syndrome. , 2007, Arthritis and rheumatism.

[18]  J. Pers,et al.  Aberrant expression of BAFF by B lymphocytes infiltrating the salivary glands of patients with primary Sjögren's syndrome. , 2007, Arthritis and rheumatism.

[19]  Donglei Zhang,et al.  Correlation of the expression levels of BLyS and its receptors mRNA in patients with systemic lupus erythematosus. , 2006, Clinical biochemistry.

[20]  I. Gunnarsson,et al.  Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rheumatoid arthritis , 2006, Arthritis research & therapy.

[21]  M. Crow,et al.  Elevated levels of soluble CD40 ligand (sCD40L) in serum of patients with systemic autoimmune diseases. , 2006, Journal of autoimmunity.

[22]  C. Cunningham-Rundles,et al.  Inflammatory and autoimmune complications of common variable immune deficiency. , 2006, Autoimmunity reviews.

[23]  M. Prelog Aging of the immune system: a risk factor for autoimmunity? , 2006, Autoimmunity reviews.

[24]  S. Fleming,et al.  Complement, natural antibodies, autoantibodies and tissue injury. , 2006, Autoimmunity reviews.

[25]  D. Alarcón-Segovia,et al.  The different faces of shared autoimmunity. , 2006, Autoimmunity reviews.

[26]  M. Pelletier,et al.  Expression and occupancy of BAFF-R on B cells in systemic lupus erythematosus. , 2005, Arthritis and rheumatism.

[27]  N. Hellings,et al.  Profiling the autoantibody repertoire by serological antigen selection. , 2005, Journal of autoimmunity.

[28]  B. Diamond,et al.  Balancing diversity and tolerance , 2005, The Journal of experimental medicine.

[29]  D. Greaves,et al.  ΔBAFF, a Splice Isoform of BAFF, Opposes Full-Length BAFF Activity In Vivo in Transgenic Mouse Models1 , 2005, The Journal of Immunology.

[30]  J. Pers,et al.  BAFF Overexpression Is Associated with Autoantibody Production in Autoimmune Diseases , 2005, Annals of the New York Academy of Sciences.

[31]  J. Tschopp,et al.  Identification of proteoglycans as the APRIL-specific binding partners , 2005, The Journal of experimental medicine.

[32]  M. Cancro The BLyS family of ligands and receptors: an archetype for niche‐specific homeostatic regulation , 2004, Immunological reviews.

[33]  Sambasiva P Rao,et al.  B Cell-Activating Factor Belonging to the TNF Family Acts through Separate Receptors to Support B Cell Survival and T Cell-Independent Antibody Formation , 2004, The Journal of Immunology.

[34]  C. Mackay,et al.  B Cell-Activating Factor Belonging to the TNF Family (BAFF)-R Is the Principal BAFF Receptor Facilitating BAFF Costimulation of Circulating T and B Cells1 , 2004, The Journal of Immunology.

[35]  P. Emery,et al.  Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis. , 2004, The New England journal of medicine.

[36]  T. Phan,et al.  Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches. , 2004, Immunity.

[37]  Y. Shoenfeld,et al.  Eighth international workshop on autoantibodies and autoimmunity Berlin, Germany, 10-13 September, 2003. , 2004, Autoimmunity reviews.

[38]  V. Roschke,et al.  B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: longitudinal observations. , 2003, Arthritis and rheumatism.

[39]  C. Ware,et al.  ΔBAFF, an Alternate Splice Isoform That Regulates Receptor Binding and Biopresentation of the B Cell Survival Cytokine, BAFF* , 2003, Journal of Biological Chemistry.

[40]  M. Nussenzweig,et al.  Predominant Autoantibody Production by Early Human B Cell Precursors , 2003, Science.

[41]  I. Sanz,et al.  The relationship of FcγRIIIa genotype to degree of B cell depletion by rituximab in the treatment of systemic lupus erythematosus , 2003 .

[42]  V. Roschke,et al.  BLyS and APRIL Form Biologically Active Heterotrimers That Are Expressed in Patients with Systemic Immune-Based Rheumatic Diseases1 , 2002, The Journal of Immunology.

[43]  D. Seshasayee,et al.  BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2. , 2002, Immunity.

[44]  Hong-shan Wang,et al.  BAFF-induced NEMO-independent processing of NF-κB2 in maturing B cells , 2002, Nature Immunology.

[45]  Eddy Arnold,et al.  Structural basis of BLyS receptor recognition , 2002, Nature Structural Biology.

[46]  H. Shu,et al.  Crystal Structure of sTALL-1 Reveals a Virus-like Assembly of TNF Family Ligands , 2002, Cell.

[47]  T. Cachero,et al.  Crystal structure of extracellular human BAFF, a TNF family member that stimulates B lymphocytes. , 2002, Journal of molecular biology.

[48]  P. Lipsky Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity , 2001, Nature Immunology.

[49]  M. Scott,et al.  An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent Pathway , 2001, Science.

[50]  V. Dixit,et al.  Activation and accumulation of B cells in TACI-deficient mice , 2001, Nature Immunology.

[51]  G. Alarcón,et al.  Cutting Edge: A Role for B Lymphocyte Stimulator in Systemic Lupus Erythematosus1 , 2001, The Journal of Immunology.

[52]  J. Tschopp,et al.  Baff Mediates Survival of Peripheral Immature B Lymphocytes , 2000, The Journal of experimental medicine.

[53]  Tom Boone,et al.  APRIL and TALL-1 and receptors BCMA and TACI: system for regulating humoral immunity , 2000, Nature Immunology.

[54]  J. Tschopp,et al.  Mice Transgenic for Baff Develop Lymphocytic Disorders along with Autoimmune Manifestations , 1999, The Journal of experimental medicine.

[55]  J. Tschopp,et al.  BAFF, a Novel Ligand of the Tumor Necrosis Factor Family, Stimulates B Cell Growth , 1999, The Journal of experimental medicine.

[56]  J. Cyster,et al.  Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire , 1994, Nature.

[57]  J. Tschopp,et al.  Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome. , 2002, The Journal of clinical investigation.