Interleukin-6 and tumor necrosis factor-alpha levels increase in response to maximal exercise in patients with chronic heart failure.

[1]  H. Drexler,et al.  The Role of Interleukin-6 in the Failing Heart , 2001, Heart Failure Reviews.

[2]  D. Mann.  Recent Insights into the Role of Tumor Necrosis Factor in the Failing Heart , 2001, Heart Failure Reviews.

[3]  L. Saccá,et al.  Differential expression of TNF-alpha, IL-6, and IGF-1 by graded mechanical stress in normal rat myocardium. , 2002, American journal of physiology. Heart and circulatory physiology.

[4]  A. Coats,et al.  Physical training modulates proinflammatory cytokines and the soluble Fas/soluble Fas ligand system in patients with chronic heart failure. , 2002, Journal of the American College of Cardiology.

[5]  S. Anker,et al.  High tumour necrosis factor-alpha levels are associated with exercise intolerance and neurohormonal activation in chronic heart failure patients. , 2001, Cytokine.

[6]  A. Coats,et al.  Physical training reduces peripheral markers of inflammation in patients with chronic heart failure. , 2001, European heart journal.

[7]  G. Dehmer,et al.  Elevated interleukin-6 levels in patients with asymptomatic left ventricular systolic dysfunction. , 2001, American heart journal.

[8]  B. Bozkurt,et al.  Results of Targeted Anti–Tumor Necrosis Factor Therapy With Etanercept (ENBREL) in Patients With Advanced Heart Failure , 2001, Circulation.

[9]  R. Shephard,et al.  The Cytokine Response to Physical Activity and Training , 2001, Sports medicine.

[10]  B. Saltin,et al.  Production of interleukin‐6 in contracting human skeletal muscles can account for the exercise‐induced increase in plasma interleukin‐6 , 2000, The Journal of physiology.

[11]  Roy J. Shephard,et al.  Exercise elevates plasma levels but not gene expression of IL-1β, IL-6, and TNF-α in blood mononuclear cells , 2000 .

[12]  H. Ullum,et al.  Changes in plasma concentrations of interleukin-6 and interleukin-1 receptor antagonists in response to adrenaline infusion in humans , 2000, European Journal of Applied Physiology.

[13]  L Hoffman-Goetz,et al.  Exercise and the immune system: regulation, integration, and adaptation. , 2000, Physiological reviews.

[14]  D. Wagner,et al.  The role of tumor necrosis factor in the pathophysiology of heart failure. , 2000, Journal of the American College of Cardiology.

[15]  R. Shephard,et al.  Impact of three different types of exercise on components of the inflammatory response , 1999, European Journal of Applied Physiology and Occupational Physiology.

[16]  Peter Schjerling,et al.  Pro‐ and anti‐inflammatory cytokine balance in strenuous exercise in humans , 1999, The Journal of physiology.

[17]  S. Frøland,et al.  Cytokine network in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. , 1999, The American journal of cardiology.

[18]  A. Turnbull,et al.  Regulation of the hypothalamic-pituitary-adrenal axis by cytokines: actions and mechanisms of action. , 1999, Physiological reviews.

[19]  B. Pedersen,et al.  A trauma‐like elevation of plasma cytokines in humans in response to treadmill running , 1998, The Journal of physiology.

[20]  I. Hisatome,et al.  Sympathetic nervous response relative to the adenosine triphosphate supply-demand imbalance during exercise is augmented in patients with heart failure. , 1998, Chest.

[21]  D. Fukai,et al.  Interleukin-6 spillover in the peripheral circulation increases with the severity of heart failure, and the high plasma level of interleukin-6 is an important prognostic predictor in patients with congestive heart failure. , 1998, Journal of the American College of Cardiology.

[22]  D. Papanicolaou,et al.  The Pathophysiologic Roles of Interleukin-6 in Human Disease , 1998, Annals of Internal Medicine.

[23]  D. Papanicolaou,et al.  Dose-dependent effects of recombinant human interleukin-6 on glucose regulation. , 1997, The Journal of clinical endocrinology and metabolism.

[24]  H. Oral,et al.  Hemodynamic regulation of tumor necrosis factor-alpha gene and protein expression in adult feline myocardium. , 1997, Circulation research.

[25]  P. Ponikowski,et al.  Hormonal changes and catabolic/anabolic imbalance in chronic heart failure and their importance for cardiac cachexia. , 1997, Circulation.

[26]  B. Pedersen,et al.  Exercise‐induced increase in serum interleukin‐6 in humans is related to muscle damage. , 1997, The Journal of physiology.

[27]  D. Papanicolaou,et al.  Exercise stimulates interleukin-6 secretion: inhibition by glucocorticoids and correlation with catecholamines. , 1996, The American journal of physiology.

[28]  H. Oral,et al.  Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: a report from the Studies of Left Ventricular Dysfunction (SOLVD). , 1996, Journal of the American College of Cardiology.

[29]  M. Munger,et al.  Circulating concentrations of proinflammatory cytokines in mild or moderate heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. , 1996, The American journal of cardiology.

[30]  T. van der Poll,et al.  Endocrinologic and metabolic effects of interleukin-6 in humans. , 1995, The American journal of physiology.

[31]  R. Derijk,et al.  Induction of plasma interleukin-6 by circulating adrenaline in the rat , 1994, Psychoneuroendocrinology.

[32]  Y. Ashihara,et al.  Highly Sensitive Chemiluminescent Enzyme Immunoassay with Gelatin-Coated Ferrite Solid Phase , 1994 .

[33]  J. Bousquet,et al.  Release of cytokines by blood monocytes during strenuous exercise. , 1994, International journal of sports medicine.

[34]  Y. Ohkura,et al.  Fluorogenic reagents for the derivatization of catecholamines and related compounds for liquid chromatographic analysis of biological samples , 1992 .

[35]  P. Vassalli,et al.  The pathophysiology of tumor necrosis factors. , 1992, Annual review of immunology.

[36]  H. Itoh,et al.  Light and Electron Microscopic Localization of Brain Natriuretic Peptide in Relation to Atrial Natriuretic Peptide in Porcine Atrium: Immunohistocytochemical Study Using Specific Monoclonal Antibodies , 1991, Circulation.

[37]  H. Imura,et al.  Natriuretic peptides as cardiac hormones in normotensive and spontaneously hypertensive rats. The ventricle is a major site of synthesis and secretion of brain natriuretic peptide. , 1991, Circulation research.

[38]  K. Inouye,et al.  Brain natriuretic peptide as a novel cardiac hormone in humans. Evidence for an exquisite dual natriuretic peptide system, atrial natriuretic peptide and brain natriuretic peptide. , 1991, The Journal of clinical investigation.

[39]  L. Aarden,et al.  The relation among stress, adrenalin, interleukin 6 and acute phase proteins in the rat. , 1990, Clinical immunology and immunopathology.

[40]  H. Fillit,et al.  Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. , 1990, The New England journal of medicine.

[41]  R. Casaburi,et al.  Metabolic acidosis during exercise in patients with chronic obstructive pulmonary disease. Use of the V-slope method for anaerobic threshold determination. , 1988, Chest.

[42]  G. Thamsborg,et al.  Atrial natriuretic factor during exercise in patients with congestive heart failure. , 1988, Acta endocrinologica.

[43]  R Gorlin,et al.  Problems in echocardiographic volume determinations: echocardiographic-angiographic correlations in the presence of absence of asynergy. , 1976, The American journal of cardiology.