Selective Fluorogenic Sensing of As(III) Using Aptamer-Capped Nanomaterials.

Organic-inorganic hybrid nanomaterials offer extremely valuable tools for monitoring many types of analytes in solution. Within this framework, aptamer-based nanomaterials for heavy metal detection are still very scarce. Herein, a novel sensing nanoprobe for the selective and sensitive detection of As(III) based on the combination of aptamers with mesoporous silica nanoparticles has been developed. The efficiency of the sensor is demonstrated in environmental conditions, showing a great potential in As(III) monitoring assays.

[1]  Fritz H. Frimmel,et al.  Arsenic — a Review. Part I: Occurrence, Toxicity, Speciation, Mobility , 2003 .

[2]  T. Bein,et al.  Multifunctional Mesoporous Silica Nanoparticles as a Universal Platform for Drug Delivery , 2014 .

[3]  Lan He,et al.  Nanoparticles assembled by aptamers and crystal violet for arsenic(III) detection in aqueous solution based on a resonance Rayleigh scattering spectral assay. , 2012, Nanoscale.

[4]  Zhongpin Zhang,et al.  Color-Multiplexing-Based Fluorescent Test Paper: Dosage-Sensitive Visualization of Arsenic(III) with Discernable Scale as Low as 5 ppb. , 2016, Analytical chemistry.

[5]  Z. Zheng,et al.  Bioinspired nanovalves with selective permeability and pH sensitivity. , 2015, Nanoscale.

[6]  M. Soylak,et al.  Selective speciation and determination of inorganic arsenic in water, food and biological samples. , 2010, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[7]  X. Yan,et al.  Determination of (ultra)trace amounts of arsenic(III) and arsenic(V) in water by inductively coupled plasma mass spectrometry coupled with flow injection on-line sorption preconcentration and separation in a knotted reactor. , 1998, Analytical chemistry.

[8]  Luis M Liz-Marzán,et al.  Surface Enhanced Raman Scattering and Gated Materials for Sensing Applications: The Ultrasensitive Detection of Mycoplasma and Cocaine. , 2016, Chemistry.

[9]  M. Yu Colorimetric Detection of Trace Arsenic(III) in Aqueous Solution Using Arsenic Aptamer and Gold Nanoparticles , 2014 .

[10]  B. Rezaei,et al.  A simple and sensitive fluorimetric aptasensor for the ultrasensitive detection of arsenic(III) based on cysteamine stabilized CdTe/ZnS quantum dots aggregation. , 2016, Biosensors & bioelectronics.

[11]  Bin Su,et al.  Programmable DNA switch for bioresponsive controlled release , 2011 .

[12]  Kazuo T. Suzuki,et al.  Arsenic round the world: a review. , 2002, Talanta.

[13]  S. Atılgan,et al.  Selective and sensitive turn-on fluorescent sensing of arsenite based on cysteine fused tetraphenylethene with AIE characteristics in aqueous media. , 2013, Chemical communications.

[14]  Kemin Wang,et al.  ATP-responsive controlled release system using aptamer-functionalized mesoporous silica nanoparticles. , 2012, Langmuir : the ACS journal of surfaces and colloids.

[15]  Nianqiang Wu,et al.  Nanostructured Sensors for Detection of Heavy Metals: A Review , 2013 .

[16]  S. Shariati,et al.  Aptamer conjugated silver nanoparticles for the colorimetric detection of arsenic ions using response surface methodology , 2015 .

[17]  Shenshan Zhan,et al.  Ultrasensitive aptamer biosensor for arsenic(III) detection in aqueous solution based on surfactant-induced aggregation of gold nanoparticles. , 2012, The Analyst.

[18]  R. Eritja,et al.  An aptamer-gated silica mesoporous material for thrombin detection. , 2013, Chemical communications.

[19]  R. Martínez‐Máñez,et al.  Gated Silica Mesoporous Materials in Sensing Applications , 2015, ChemistryOpen.

[20]  T. Harrop,et al.  Synthesis and properties of arsenic(III)-reactive coumarin-appended benzothiazolines: a new approach for inorganic arsenic detection. , 2013, Inorganic chemistry.

[21]  X Chris Le,et al.  Aptamers facilitating amplified detection of biomolecules. , 2015, Analytical chemistry.

[22]  H. Möhwald,et al.  Self‐Healing and Antifouling Multifunctional Coatings Based on pH and Sulfide Ion Sensitive Nanocontainers , 2013 .

[23]  Sunil Mittal,et al.  Advances in arsenic biosensor development--a comprehensive review. , 2015, Biosensors & bioelectronics.

[24]  Elena Aznar,et al.  Gated Materials for On-Command Release of Guest Molecules. , 2016, Chemical reviews.

[25]  V. C. Özalp,et al.  Small molecule detection by lateral flow strips via aptamer-gated silica nanoprobes. , 2016, The Analyst.

[26]  J. Jaworski,et al.  Controlled release using mesoporous silica nanoparticles functionalized with 18-crown-6 derivative , 2011 .

[27]  Bin Su,et al.  DNA-based intelligent logic controlled release systems. , 2012, Chemical communications.

[28]  Ji-Hye Han,et al.  Arsenic removal from Vietnamese groundwater using the arsenic-binding DNA aptamer. , 2009, Environmental science & technology.

[29]  D. Shchukin,et al.  A cost-effective pH-sensitive release system for water source pH detection. , 2014, Chemical communications.

[30]  E. Pérez-Payá,et al.  Enzyme-mediated controlled release systems by anchoring peptide sequences on mesoporous silica supports. , 2011, Angewandte Chemie.

[31]  J. Aggett,et al.  The determination of arsenic(III) and total arsenic by atomic-absorption spectroscopy. , 1976, The Analyst.