MILA – multilevel immune learning algorithm and its application to anomaly detection

T-cell-dependent humoral immune response is one of the more complex immunological events in the biological immune system, involving interaction of B cells with antigen (Ag) and their proliferation, differentiation and subsequent secretion of antibody (Ab). Inspired by these immunological principles, a Multilevel Immune Learning Algorithm (MILA) is proposed for novel pattern recognition. This paper describes the detailed background of MILA, and outlines its main features in different phases: Initialization phase, Recognition phase, Evolutionary phase and Response phase. Different test problems are studied and experimented with MILA for performance evaluation. The results show MILA is flexible and efficient in detecting anomalies and novel patterns.

[1]  Prabhat Hajela,et al.  Immune network modelling in design optimization , 1999 .

[2]  Munindar P. Singh,et al.  Readings in agents , 1997 .

[3]  Paul Helman,et al.  An immunological approach to change detection: algorithms, analysis and implications , 1996, Proceedings 1996 IEEE Symposium on Security and Privacy.

[4]  Michael Wooldridge,et al.  Multiagent Systems: A Modern Approach to Distributed Artificial Intelligence , 1999 .

[5]  G. F. Burton,et al.  Follicular dendritic cells and presentation of antigen and costimulatory signals to B cells , 1997, Immunological reviews.

[6]  Stephanie Forrest,et al.  Infect Recognize Destroy , 1996 .

[7]  G. Thorbecke,et al.  The Biology of Germinal Centers in Lymphoid Tissue , 1998, Springer Berlin Heidelberg.

[8]  Gerhard Weiss,et al.  Multiagent systems: a modern approach to distributed artificial intelligence , 1999 .

[9]  Fernando José Von Zuben,et al.  Learning and optimization using the clonal selection principle , 2002, IEEE Trans. Evol. Comput..

[10]  G. Thorbecke,et al.  Biology of germinal centers in lymphoid tissue , 1994 .

[11]  J. Goodlad,et al.  Germinal centre cell kinetics , 1998, The Journal of pathology.

[12]  J. Banchereau,et al.  Follicular dendritic cells and germinal centers. , 1996, International review of cytology.

[13]  Dipankar Dasgupta,et al.  An Anomaly Entection Algorithm Inspired by the Immune Syste , 1999 .

[14]  D. Dasgupta Artificial Immune Systems and Their Applications , 1998, Springer Berlin Heidelberg.

[15]  Ferat Sahin,et al.  An AIS approach to a color image classification problem in a real time industrial application , 2001, 2001 IEEE International Conference on Systems, Man and Cybernetics. e-Systems and e-Man for Cybernetics in Cyberspace (Cat.No.01CH37236).

[16]  David H. Ackley,et al.  Building diverse computer systems , 1997, Proceedings. The Sixth Workshop on Hot Topics in Operating Systems (Cat. No.97TB100133).

[17]  G. Oster,et al.  Theoretical studies of clonal selection: minimal antibody repertoire size and reliability of self-non-self discrimination. , 1979, Journal of theoretical biology.

[18]  Alan S. Perelson,et al.  Self-nonself discrimination in a computer , 1994, Proceedings of 1994 IEEE Computer Society Symposium on Research in Security and Privacy.

[19]  H.,et al.  The Immune System as a Model for Pattern Recognition and Classification , 1999 .