Isopentenyl-diphosphate isomerase is essential for viability of Caenorhabditis elegans

[1]  H. Horvitz,et al.  The engulfment process of programmed cell death in caenorhabditis elegans. , 2004, Annual review of cell and developmental biology.

[2]  Daniel J Klionsky,et al.  Development by self-digestion: molecular mechanisms and biological functions of autophagy. , 2004, Developmental cell.

[3]  S. Slaugenhaupt,et al.  Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[4]  R. Hopkin,et al.  Enzyme therapy for lysosomal storage disease: principles, practice, and prospects. , 2003, Annual review of genomics and human genetics.

[5]  D. Hall,et al.  Autophagy Genes Are Essential for Dauer Development and Life-Span Extension in C. elegans , 2003, Science.

[6]  S. Ward,et al.  Why do worms need cholesterol? , 2003, Nature Cell Biology.

[7]  S. Walkley.  Neurobiology and cellular pathogenesis of glycolipid storage diseases. , 2003, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[8]  C. Burd,et al.  Dual prenylation is required for Rab protein localization and function. , 2003, Molecular biology of the cell.

[9]  J. Wouters,et al.  Catalytic Mechanism of Escherichia coli Isopentenyl Diphosphate Isomerase Involves Cys-67, Glu-116, and Tyr-104 as Suggested by Crystal Structures of Complexes with Transition State Analogues and Irreversible Inhibitors* , 2003, The Journal of Biological Chemistry.

[10]  R. Roskoski,et al.  Protein prenylation: a pivotal posttranslational process. , 2003, Biochemical and biophysical research communications.

[11]  I. Varela,et al.  Identification, functional expression and enzymic analysis of two distinct CaaX proteases from Caenorhabditis elegans. , 2003, The Biochemical journal.

[12]  P. Saftig,et al.  At the acidic edge: emerging functions for lysosomal membrane proteins. , 2003, Trends in cell biology.

[13]  Thomas Blumenthal,et al.  Caenorhabditis elegans operons: form and function , 2003, Nature Reviews Genetics.

[14]  K. von Figura,et al.  Role of LAMP-2 in lysosome biogenesis and autophagy. , 2002, Molecular biology of the cell.

[15]  Erika Hartwieg,et al.  The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[16]  W. Gish,et al.  Rapid gene mapping in Caenorhabditis elegans using a high density polymorphism map , 2001, Nature Genetics.

[17]  I. Greenwald,et al.  Regulation of endocytosis by CUP-5, the Caenorhabditis elegans mucolipin-1 homolog , 2001, Nature Genetics.

[18]  S. Sturley,et al.  Conservation of eukaryotic sterol homeostasis: new insights from studies in budding yeast. , 2000, Biochimica et biophysica acta.

[19]  H. Horvitz,et al.  CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans , 2000, Nature Cell Biology.

[20]  K. Kornfeld,et al.  A local, high-density, single-nucleotide polymorphism map used to clone Caenorhabditis elegans cdf-1. , 1999, Genetics.

[21]  Min Han,et al.  A new marker for mosaic analysis in Caenorhabditis elegans indicates a fusion between hyp6 and hyp7, two major components of the hypodermis. , 1998, Genetics.

[22]  M. Prescott,et al.  Isoprenylation of polypeptides in the nematode Caenorhabditis elegans. , 1998, Biochimica et biophysica acta.

[23]  S. Walkley.  Cellular Pathology of Lysosomal Storage Disorders , 1998, Brain pathology.

[24]  Thomas L. Madden,et al.  Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. , 1997, Nucleic acids research.

[25]  C. Der,et al.  Farnesyltransferase inhibitors and cancer treatment: targeting simply Ras? , 1997, Biochimica et biophysica acta.

[26]  M. Han,et al.  Ras is required for a limited number of cell fates and not for general proliferation in Caenorhabditis elegans , 1997, Molecular and cellular biology.

[27]  D. Hall,et al.  Neuropathology of Degenerative Cell Death in Caenorhabditis elegans , 1997, The Journal of Neuroscience.

[28]  E. Hedgecock,et al.  The ncl-1 gene and genetic mosaics of Caenorhabditis elegans. , 1995, Genetics.

[29]  Min Han,et al.  Ras farnesyltransferase inhibitors suppress the phenotype resulting from an activated ras mutation in Caenorhabditis elegans. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[30]  C. Poulter,et al.  Identification of Cys139 and Glu207 as catalytically important groups in the active site of isopentenyl diphosphate:dimethylallyl diphosphate isomerase. , 1994, Biochemistry.

[31]  A. Chambers,et al.  A human promyelocyte mRNA transiently induced by TPA is homologous to yeast IPP isomerase. , 1994, Genomics.

[32]  D. Stillman,et al.  Disruption and mapping of IDI1, the gene for isopentenyl diphosphate isomerase in Saccharomyces cerevisiae , 1992, Yeast.

[33]  V. Ambros,et al.  Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences. , 1991, The EMBO journal.

[34]  H. Horvitz,et al.  Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction , 1990, Nature.

[35]  P. Sternberg,et al.  let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein , 1990, Cell.

[36]  E. Hedgecock,et al.  Limitation of the size of the vulval primordium of Caenorhabditis elegans by lin-15 expression in surrounding hypodermis , 1990, Nature.

[37]  C. Poulter,et al.  Isopentenyl diphosphate:dimethylallyl diphosphate isomerase. An improved purification of the enzyme and isolation of the gene from Saccharomyces cerevisiae. , 1989, The Journal of biological chemistry.

[38]  N. Munakata.  [Genetics of Caenorhabditis elegans]. , 1989, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.

[39]  J. Sulston,et al.  The embryonic cell lineage of the nematode Caenorhabditis elegans. , 1983, Developmental biology.

[40]  J. Sulston,et al.  Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans. , 1983, Science.

[41]  J. Sulston,et al.  Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. , 1977, Developmental biology.

[42]  R. Verpoorte,et al.  Isopentenyl diphosphate isomerase: a core enzyme in isoprenoid biosynthesis. A review of its biochemistry and function. , 1997, Natural product reports.

[43]  P. Casey,et al.  Protein prenylation: molecular mechanisms and functional consequences. , 1996, Annual review of biochemistry.

[44]  D. Hall,et al.  Electron microscopy and three-dimensional image reconstruction. , 1995, Methods in cell biology.

[45]  Andrew Fire,et al.  Chapter 19 DNA Transformation , 1995 .

[46]  R. Porter,et al.  DNA transformation. , 1988, Methods in enzymology.

[47]  A. Wyllie,et al.  Cell death: the significance of apoptosis. , 1980, International review of cytology.