Andrographolide Loaded in Micro- and Nano-Formulations: Improved Bioavailability, Target-Tissue Distribution, and Efficacy of the “King of Bitters”

[1]  Shao-Ru Chen,et al.  Overview of pharmacological activities of Andrographis paniculata and its major compound andrographolide , 2018, Critical reviews in food science and nutrition.

[2]  A. Bilia,et al.  Stealth and Cationic Nanoliposomes as Drug Delivery Systems to Increase Andrographolide BBB Permeability , 2018, Pharmaceutics.

[3]  J. Xie,et al.  Novel nanocrystal-based solid dispersion with high drug loading, enhanced dissolution, and bioavailability of andrographolide , 2018, International journal of nanomedicine.

[4]  Qin Xu,et al.  Liposomal Codelivery of Doxorubicin and Andrographolide Inhibits Breast Cancer Growth and Metastasis. , 2018, Molecular pharmaceutics.

[5]  M. Mazumder,et al.  Andrographolide engineered gold nanoparticle to overcome drug resistant visceral leishmaniasis , 2018, Artificial cells, nanomedicine, and biotechnology.

[6]  Ming-Tsang Wu,et al.  Nanoemulsion as a strategy for improving the oral bioavailability and anti-inflammatory activity of andrographolide , 2018, International journal of nanomedicine.

[7]  Shiyong Song,et al.  mPEG-PLA Micelle for Delivery of Effective Parts of Andrographis Paniculata. , 2017, Current Drug Delivery.

[8]  A. Bilia,et al.  Solid lipid nanoparticles for delivery of andrographolide across the blood-brain barrier: in vitro and in vivo evaluation. , 2018, Colloids and surfaces. B, Biointerfaces.

[9]  A. Pawar,et al.  In Vitro and In Vivo Performance of Novel Spray Dried Andrographolide Loaded Scleroglucan Based Formulation for Dry Powder Inhaler. , 2017, Current Drug Delivery.

[10]  M. Smieško,et al.  Andrographolide‐loaded nanoparticles for brain delivery: Formulation, characterisation and in vitro permeability using hCMEC/D3 cell line , 2017, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[11]  Won Jong Kim,et al.  Andrographolide‐loaded polymerized phenylboronic acid nanoconstruct for stimuli‐responsive chemotherapy , 2017, Journal of controlled release : official journal of the Controlled Release Society.

[12]  Yiguang Jin,et al.  Liposomal andrographolide dry powder inhalers for treatment of bacterial pneumonia via anti-inflammatory pathway. , 2017, International journal of pharmaceutics.

[13]  A. Karioti,et al.  A Validated Method for the Quality Control of Andrographis paniculata Preparations , 2017, Planta Medica.

[14]  Donghua Di,et al.  A novel nanosuspension of andrographolide: Preparation, characterization and passive liver target evaluation in rats , 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[15]  Ming Yang,et al.  A Natural Triterpenoid Saponin as Multifunctional Stabilizer for Drug Nanosuspension Powder , 2017, AAPS PharmSciTech.

[16]  Ting Chen,et al.  Fabrication and in vitro/in vivo evaluation of amorphous andrographolide nanosuspensions stabilized by d-α-tocopheryl polyethylene glycol 1000 succinate/sodium lauryl sulfate , 2017, International journal of nanomedicine.

[17]  A. Bilia,et al.  Improving on Nature: The Role of Nanomedicine in the Development of Clinical Natural Drugs , 2012, Planta Medica.

[18]  Ming Yang,et al.  Design and Evaluation of Novel Solid Self-Nanodispersion Delivery System for Andrographolide , 2016, AAPS PharmSciTech.

[19]  V. K. Rai,et al.  Polysaccharide Encrusted Multilayered Nano-Colloidal System of Andrographolide for Improved Hepatoprotection , 2016, AAPS PharmSciTech.

[20]  A. Fadda,et al.  Vesicles and micelles: Two versatile vectors for the delivery of natural products , 2016 .

[21]  Krishna Das Saha,et al.  Enhanced protective activity of nano formulated andrographolide against arsenic induced liver damage. , 2015, Chemico-biological interactions.

[22]  F. Wang,et al.  Development of andrographolide loaded PLGA microspheres: optimization, characterization and in vitro-in vivo correlation. , 2014, International journal of pharmaceutics.

[23]  A. Mukherjee,et al.  Engineered andrographolide nanosystems for smart recovery in hepatotoxic conditions , 2014, International journal of nanomedicine.

[24]  Michael A Repka,et al.  Andrographolide-loaded PLGA-PEG-PLGA micelles to improve its bioavailability and anticancer efficacy , 2014, Expert opinion on drug delivery.

[25]  F. Ahmad,et al.  Solid lipid nanoparticles of anticancer drug andrographolide: formulation, in vitro and in vivo studies , 2014, Drug development and industrial pharmacy.

[26]  J. J. Zhang,et al.  Preparation and characterisation of andrographolide niosomes and its anti-hepatocellular carcinoma activity , 2014, Journal of microencapsulation.

[27]  H. Wei,et al.  Preparation of andrographolide-loaded solid lipid nanoparticles and their in vitro and in vivo evaluations: characteristics, release, absorption, transports, pharmacokinetics, and antihyperlipidemic activity. , 2013, Journal of pharmaceutical sciences.

[28]  N. Khurana,et al.  Enhancement of absorption and hepatoprotective potential through soya-phosphatidylcholine-andrographolide vesicular system , 2013, Journal of liposome research.

[29]  A. Panossian,et al.  Efficacy of Andrographis paniculata in Upper Respiratory Tract Infectious Diseases and the Mechanism of Action , 2013 .

[30]  U. Chatterji,et al.  Nanoparticle engineering enhances anticancer efficacy of andrographolide in MCF-7 cells and mice bearing EAC. , 2012, Current Pharmaceutical Biotechnology.

[31]  X. Niu,et al.  Preparation and evaluation of andrographolide-loaded microemulsion , 2012, Journal of microencapsulation.

[32]  D. Mcclements.  Nanoemulsions versus microemulsions: terminology, differences, and similarities , 2012 .

[33]  A. Mukherjee,et al.  Andrographolide nanoparticles in leishmaniasis: characterization and in vitro evaluations , 2010, International journal of nanomedicine.

[34]  R. Saxena,et al.  A randomized double blind placebo controlled clinical evaluation of extract of Andrographis paniculata (KalmCold) in patients with uncomplicated upper respiratory tract infection. , 2010, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[35]  P. Mukherjee,et al.  Enhancing bioavailability and hepatoprotective activity of andrographolide from Andrographis paniculata, a well-known medicinal food, through its herbosome. , 2010, Journal of the science of food and agriculture.

[36]  R. Saxena,et al.  A randomized double blind placebo controlled clinical evaluation of extract of Andrographis paniculata ( KalmColdTM ) in patients with uncomplicated upper respiratory tract infection , 2010 .

[37]  A. Pawar,et al.  Improved bioavailability of orally administered andrographolide from pH-sensitive nanoparticles , 2010, European Journal of Drug Metabolism and Pharmacokinetics.

[38]  C. China Pharmacopoeia,et al.  Pharmacopoeia of the People's Republic of China , 2010 .

[39]  Vincent M. Rotello,et al.  Multimodal drug delivery using gold nanoparticles. , 2009, Nanoscale.

[40]  M. Pk,et al.  Entrapment of andrographolide in cross-linked alginate pellets: II. Physicochemical characterization to study the pelletization of andrographolide. , 2007, Pakistan journal of pharmaceutical sciences.

[41]  M. Pk,et al.  Entrapment of andrographolide in cross-linked alginate pellets: I. Formulation and evaluation of associated release kinetics. , 2007, Pakistan journal of pharmaceutical sciences.

[42]  N. Poolsup,et al.  Andrographis paniculata in the symptomatic treatment of uncomplicated upper respiratory tract infection: systematic review of randomized controlled trials , 2004, Journal of clinical pharmacy and therapeutics.

[43]  N. Das,et al.  Targeting of liposomal andrographolide to L. donovani-infected macrophages in vivo. , 2000, Drug delivery.

[44]  V. Thamlikitkul,et al.  Efficacy of Andrographis paniculata, Nees for pharyngotonsillitis in adults. , 1991, Journal of the Medical Association of Thailand = Chotmaihet thangphaet.