The role of TNFα and TNF receptors in obesity and insulin resistance
暂无分享,去创建一个
[1] J. Kolls,et al. An in Vivo Model for Elucidation of the Mechanism of Tumor Necrosis Factor-α (TNF-α)-Induced Insulin Resistance: Evidence for Differential Regulation of Insulin Signaling by TNF-α. , 1998, Endocrinology.
[2] K. Uysal,et al. Functional analysis of tumor necrosis factor (TNF) receptors in TNF-alpha-mediated insulin resistance in genetic obesity. , 1998, Endocrinology.
[3] T. Wadden,et al. Tumor Necrosis Factor-α in Sera of Obese Patients: Fall with Weight Loss , 1998 .
[4] H. Lithell,et al. Relation Between Plasma Tumor Necrosis Factor-α and Insulin Sensitivity in Elderly Men With Non–Insulin-Dependent Diabetes Mellitus , 1998 .
[5] D. Salamon,et al. Elevated serum tumour necrosis factor-alpha levels can contribute to the insulin resistance in Type II (non-insulin-dependent) diabetes and in obesity , 1998, Diabetologia.
[6] A. Ullrich,et al. Protein kinase C isoforms α, δ and θ require insulin receptor substrate-1 to inhibit the tyrosine kinase activity of the insulin receptor in human kidney embryonic cells (HEK 293 cells) , 1998, Diabetologia.
[7] H. Hauner,et al. Tumor necrosis factor-alpha acutely inhibits insulin signaling in human adipocytes: implication of the p80 tumor necrosis factor receptor. , 1998, Diabetes.
[8] M. Benito,et al. Tumor Necrosis Factor-α Causes Insulin Receptor Substrate-2-Mediated Insulin Resistance and Inhibits Insulin-Induced Adipogenesis in Fetal Brown Adipocytes. , 1998, Endocrinology.
[9] D. Salamon,et al. Increased interleukin-12 plasma concentrations in both, insulin-dependent and non-insulin-dependent diabetes mellitus , 1998, Diabetologia.
[10] H. Lithell,et al. Relation between plasma tumor necrosis factor-alpha and insulin sensitivity in elderly men with non-insulin-dependent diabetes mellitus. , 1998, Arteriosclerosis, thrombosis, and vascular biology.
[11] A. Ullrich,et al. Protein kinase C isoforms alpha, delta and theta require insulin receptor substrate-1 to inhibit the tyrosine kinase activity of the insulin receptor in human kidney embryonic cells (HEK 293 cells). , 1998, Diabetologia.
[12] M. Benito,et al. Tumor necrosis factor-alpha causes insulin receptor substrate-2-mediated insulin resistance and inhibits insulin-induced adipogenesis in fetal brown adipocytes. , 1998, Endocrinology.
[13] T. Wadden,et al. Tumor necrosis factor-alpha in sera of obese patients: fall with weight loss. , 1998, The Journal of clinical endocrinology and metabolism.
[14] D. Leroith,et al. A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation. , 2009, The Journal of biological chemistry.
[15] T. Kirchgessner,et al. Tumor necrosis factor-alpha contributes to obesity-related hyperleptinemia by regulating leptin release from adipocytes. , 1997, The Journal of clinical investigation.
[16] H. Mischak,et al. Protein kinase C (PKC) ϵ enhances the inhibitory effect of TNFα on insulin signaling in HEK293 cells , 1997 .
[17] K. Uysal,et al. Protection from obesity-induced insulin resistance in mice lacking TNF-α function , 1997, Nature.
[18] Margaret S. Wu,et al. Targeted Disruption of the Tumor Necrosis Factor-α Gene: Metabolic Consequences in Obese and Nonobese Mice , 1997, Diabetes.
[19] G. Boden. Role of Fatty Acids in the Pathogenesis of Insulin Resistance and NIDDM , 1997, Diabetes.
[20] K. Uysal,et al. Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. , 1997, Nature.
[21] Bruce M. Spiegelman,et al. Uncoupling of Obesity from Insulin Resistance Through a Targeted Mutation in aP2, the Adipocyte Fatty Acid Binding Protein , 1996, Science.
[22] B. Cohen,et al. Modulation of Insulin Activities by Leptin , 1996, Science.
[23] Roy Taylor,et al. Effects of an Engineered Human Anti–TNF-α Antibody (CDP571) on Insulin Sensitivity and Glycemic Control in Patients With NIDDM , 1996, Diabetes.
[24] B. Spiegelman,et al. Tumor Necrosis Factor (TNF)-α Inhibits Insulin Signaling through Stimulation of the p55 TNF Receptor and Activation of Sphingomyelinase* , 1996, The Journal of Biological Chemistry.
[25] A. Ullrich,et al. Tumor necrosis factor-alpha- and hyperglycemia-induced insulin resistance. Evidence for different mechanisms and different effects on insulin signaling. , 1996, The Journal of clinical investigation.
[26] R. Henry,et al. The expression of TNF alpha by human muscle. Relationship to insulin resistance. , 1996, The Journal of clinical investigation.
[27] B. Spiegelman,et al. IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance , 1996, Science.
[28] B. Lowell,et al. Characterization of Insulin Resistance and NIDDM in Transgenic Mice With Reduced Brown Fat , 1995, Diabetes.
[29] M. Papa,et al. Tumor Necrosis Factor α-induced Phosphorylation of Insulin Receptor Substrate-1 (IRS-1) , 1995, The Journal of Biological Chemistry.
[30] M. Papa,et al. Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1). Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1. , 1995, The Journal of biological chemistry.
[31] A. Stenbit,et al. Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4 , 1995, Nature.
[32] R. Simsolo,et al. The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. , 1995, The Journal of clinical investigation.
[33] B. Spiegelman,et al. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. , 1995, The Journal of clinical investigation.
[34] G. Reaven,et al. Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus , 1995, Nature.
[35] B. Spiegelman,et al. Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha. , 1994, The Journal of clinical investigation.
[36] B. Spiegelman,et al. Tumor necrosis factor alpha inhibits signaling from the insulin receptor. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[37] B. Spiegelman,et al. Altered gene expression for tumor necrosis factor-alpha and its receptors during drug and dietary modulation of insulin resistance. , 1994, Endocrinology.
[38] M. Papa,et al. Tumor necrosis factor-alpha suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrates. , 1993, The Journal of biological chemistry.
[39] C. Kahn,et al. Rad: a member of the Ras family overexpressed in muscle of type II diabetic humans. , 1993, Science.
[40] B. Spiegelman,et al. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. , 1993, Science.
[41] M J Saad,et al. Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance. , 1992, The Journal of clinical investigation.
[42] H. Klein,et al. Decreased kinase activity of insulin receptors from adipocytes of non-insulin-dependent diabetic subjects. , 1987, The Journal of clinical investigation.
[43] K. Ratzmann. Insulin resistance in man , 1986, Diabetologia.
[44] I. Deary,et al. Insulin resistance , 1996 .