Hearing impairment in F-111 maintenance workers: the study of health outcomes in aircraft maintenance personnel (SHOAMP) general health and medical study.

BACKGROUND We sought to examine hearing loss in a group from the Royal Australian Air Force who undertook fuel tank maintenance on F-111 aircraft, with exposure to formulations containing ototoxins, relative to two different comparison groups. METHODS Using pure-tone audiometry, hearing thresholds were assessed in 614 exposed personnel, 513 technical-trade comparisons (different base, same job), and 403 non-technical comparisons (same base, different job). We calculated percentage loss of hearing (PLH) and used regression models to examine whether there was an association between PLH and F-111 fuel tank maintenance, adjusting for possible confounders. In addition, the difference between the observed hearing thresholds and the expected thresholds based on an otologically normal population (ISO-7029-2003) was determined. RESULTS The PLH ranged from nil to 96 (median 1.5, quartiles 0.3, 5.5). A logistic regression model showed no statistically significant difference in PLH among the three exposure groups (exposed vs. non-technical controls 1.1: 95% CI 0.7, 2.0 and exposed vs. technical OR 0.9: 95% CI 0.6, 1.3). The model also highlighted a number of other risk factors for PLH including age, tinnitus, smoking, depression, and use of depression medications. However, at all eight frequencies measured, all populations had lower than expected hearing thresholds based on published ISO-7029 medians. CONCLUSIONS Although there was no difference in PLH between the three exposure groups, the study did reveal a high degree of hearing loss between the 3 groups and a normal population.

[1]  E. Krieg,et al.  Hearing loss from combined exposures among petroleum refinery workers. , 1997, Scandinavian audiology.

[3]  W BURNS,et al.  STUDY OF NOISE AND HEARING IN JUTE WEAVING. , 1965, The Journal of the Acoustical Society of America.

[4]  Jeffrey Fisher,et al.  JP-8 jet fuel can promote auditory impairment resulting from subsequent noise exposure in rats. , 2007, Toxicological sciences : an official journal of the Society of Toxicology.

[5]  F. Carricondo,et al.  Biochemical evidence for the presence of serotonin transporters in the rat cochlea , 2003, Hearing Research.

[6]  W. Dixon Ward Latent and Residual Effects in Temporary Threshold Shift , 1960 .

[7]  Charles E Bishop,et al.  Auditory measures in clinically depressed individuals. II. Auditory evoked potentials and behavioral speech tests , 2004, International journal of audiology.

[8]  B. McPherson,et al.  Organic solvents and hearing loss: The challenge for audiology , 2006, International journal of audiology.

[9]  A. Dancer,et al.  The specific problems of noise in military life. , 1998, Scandinavian audiology. Supplementum.

[10]  E. Ha,et al.  Combined effects of noise and mixed solvents exposure on the hearing function among workers in the aviation industry. , 2005, Industrial health.

[11]  K. Crofton,et al.  Trichloroethylene ototoxicity: evidence for a cochlear origin. , 1998, Toxicological sciences : an official journal of the Society of Toxicology.

[12]  Anthony M Brown,et al.  Sexual function in F-111 maintenance workers: the study of health outcomes in aircraft maintenance personnel. , 2009, The journal of sexual medicine.

[13]  D. McBride,et al.  Audiometric notch as a sign of noise induced hearing loss , 2001, Occupational and environmental medicine.

[14]  Guang-di Chen,et al.  Potentiation of noise-induced hearing loss by low concentrations of hydrogen cyanide in rats. , 2002, Toxicological sciences : an official journal of the Society of Toxicology.

[15]  Paul Succop,et al.  Effects of Concurrent Noise and Jet Fuel Exposure on Hearing Loss , 2005, Journal of occupational and environmental medicine.

[16]  T Kauppinen,et al.  From cross-tabulations to multipurpose exposure information systems: a new job-exposure matrix. , 1998, American journal of industrial medicine.

[17]  E. Krieg,et al.  Audiometric Findings in Workers Exposed to Low Levels of Styrene and Noise , 2002, Journal of occupational and environmental medicine.

[18]  Jerry L. Campbell,et al.  Promotion of noise-induced cochlear injury by toluene and ethylbenzene in the rat. , 2007, Toxicological sciences : an official journal of the Society of Toxicology.

[19]  R Cary,et al.  Effects of combined exposure to noise and toxic substances--critical review of the literature. , 1997, The Annals of occupational hygiene.

[20]  A. Svedberg,et al.  Hearing damage in military service. A study on 38,294 conscripts. , 1986, Scandinavian audiology.

[21]  J. Ylikoski,et al.  Hearing loss and handicap of professional soldiers exposed to gunfire noise. , 1994, Scandinavian journal of work, environment & health.

[22]  I Pyykkö,et al.  Hearing loss and tinnitus in Meniere's disease. , 2002, Auris, nasus, larynx.

[23]  Anthony M Brown,et al.  Neuropsychological health in F-111 aircraft maintenance workers. , 2006, Neurotoxicology.

[24]  Aleksander Aksentijevic,et al.  Effect of exposure to a mixture of solvents and noise on hearing and balance in aircraft maintenance workers. , 2005, Noise & health.

[25]  J. May Occupational hearing loss. , 2000, American journal of industrial medicine.

[26]  L W Henselman,et al.  Effects of Noise Exposure, Race, and Years of Service on Hearing in U.S. Army Soldiers , 1995, Ear and hearing.

[27]  H. Mostafa OCCUPATIONAL HEARING LOSS. , 1963, The Journal of the Egyptian Medical Association.

[28]  Mary D'Souza,et al.  Serotonin 2B receptor: Upregulated with age and hearing loss in mouse auditory system , 2007, Neurobiology of Aging.

[29]  K. Tatara,et al.  Cigarette Smoking and Risk for Hearing Impairment: A Longitudinal Study in Japanese Male Office Workers , 2000, Journal of occupational and environmental medicine.

[30]  Cleide Fernandes Teixeira,et al.  Occupational exposure to insecticides and their effects on the auditory system. , 2002, Noise & health.

[31]  G. Loquet,et al.  Styrene-induced hearing loss: a membrane insult , 2001, Hearing Research.

[32]  R. Pääkkönen,et al.  Modelling the risk of noise-induced hearing loss among military pilots. , 2004, International journal of audiology.

[33]  A. Rey L'examen clinique in psychologie , 1964 .

[34]  Eiji Yano,et al.  Hearing loss associated with smoking and occupational noise exposure in a Japanese metal working company , 2005, International archives of occupational and environmental health.

[35]  D. Monzani,et al.  Psychological profile and social behaviour of working adults with mild or moderate hearing loss. , 2008, Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale.

[36]  H Anttonen,et al.  Hearing loss and impulse noise during military service. , 1980, Scandinavian audiology. Supplementum.

[37]  E. Krieg,et al.  Toluene-induced hearing loss among rotogravure printing workers. , 1997, Scandinavian journal of work, environment & health.

[38]  J. Jokitulppo,et al.  Estimated leisure-time noise exposure, hearing thresholds, and hearing symptoms of Finnish conscripts. , 2006, Military medicine.

[39]  C. Edling,et al.  OTONEUROLOGICAL AND AUDIOLOGICAL FINDINGS IN WORKERS EXPOSED TO INDUSTRIAL SOLVENTS , 1982 .

[40]  H. Wit,et al.  Pure-tone and speech audiometry in patients with Menière's disease. , 2001, Clinical otolaryngology and allied sciences.

[41]  Charles E Bishop,et al.  Auditory measures in clinically depressed individuals. I. Basic measures and transient otoacoustic emissions , 2004, International journal of audiology.

[42]  G. Loquet,et al.  Toluene and styrene intoxication route in the rat cochlea. , 1999, Neurotoxicology and teratology.

[43]  Elena Rochtchina,et al.  Prevalence of age-related hearing loss in older adults: Blue Mountains Study. , 2009, Archives of internal medicine.

[44]  J. Goldberg,et al.  Performance of psychiatric inpatients and intellectually deficient individuals on a task that assesses the validity of memory complaints. , 1986, Journal of clinical psychology.

[45]  Per V. Bruel Do We Measure Damaging Noise Correctly , 1977 .

[46]  Anthony M Brown,et al.  Mental Health in F-111 Maintenance Workers: The Study of Health Outcomes in Aircraft Maintenance Personnel (SHOAMP) General Health and Medical Study , 2006, Journal of occupational and environmental medicine.

[47]  P. Campo,et al.  Noise and solvent, alcohol and solvent: two dangerous interactions on auditory function. , 2000, Noise & health.

[48]  J. Brokx,et al.  Interpretation of pure-tone thresholds in sensorineural hearing loss (SNHL): a review of measurement variability and age-specific references. , 2002, Acta oto-rhino-laryngologica Belgica.

[49]  M J Griffin,et al.  Raynaud's phenomenon, vibration induced white finger, and difficulties in hearing , 2002, Occupational and environmental medicine.

[50]  B. Månsson,et al.  A study of hearing changes among military conscripts in the Swedish Army , 2006, International journal of audiology.

[51]  A Axelsson,et al.  Is there an ototraumatic interaction between noise and solvents? , 1984, Scandinavian audiology.

[52]  S Williams,et al.  Characteristics of the audiometric notch as a clinical sign of noise exposure , 2001, Scandinavian audiology.

[53]  P. Campo,et al.  Toluene-induced hearing loss: a mid-frequency location of the cochlear lesions. , 1997, Neurotoxicology and teratology.

[54]  M. Hiscock,et al.  Detection of feigned cognitive impairment: The two-alternative forced-choice method compared with selected conventional tests , 1994 .