A report of a probable case of familial Guillain Barre syndrome

Although it is a sporadic disease, few studies have reported cases of Guillain Barre Syndrome (GBS) in families which postulate a genetic susceptibility. Human leukocyte antigen (HLA) typing is an area of discussion in GBS though none of them are considered definitive. In recent years, more studies have evaluated HLA typing in sporadic cases while rarely it has been assessed in familial ones. We report a woman and her daughter experiencing GBS and their HLA typing in a 2-year interval.

[1]  B. Soomro,et al.  Guillain Barre syndrome in a family: a case report of four siblings. , 2011, Journal of the College of Physicians and Surgeons--Pakistan : JCPSP.

[2]  J. Wanigasinghe,et al.  A case of possible familial Guillain-Barre syndrome. , 2010, The Ceylon medical journal.

[3]  J. Meulstee,et al.  HLA class II alleles are not a general susceptibility factor in Guillain–Barré syndrome , 2005, Neurology.

[4]  J. Houwing-Duistermaat,et al.  The occurrence of Guillain-Barré syndrome within families , 2004, Neurology.

[5]  Andrew F. Jones,et al.  An Indian , 2003 .

[6]  T. López-Alburquerque,et al.  Síndrome de Guillain-Barré por citomegalovirus en dos hermanos. Medidor del pico de flujo espiratorio como mecanismo de transmisión , 2002 .

[7]  E. Granieri,et al.  Epidemiology of the Guillain-Barré syndrome , 2001, Current opinion in neurology.

[8]  Z. Yan,et al.  HLA alleles in patients with Guillain-Barre syndrome. , 2000, Chinese medical journal.

[9]  R. Vaughan,et al.  Familial Guillain—Barré Syndrome , 1999, European journal of neurology.

[10]  Gourie-Devi.  Annals Of Indian Academy Of Neurology , 1999 .

[11]  G. Mckhann,et al.  Differential distribution of HLA alleles in two forms of Guillain-Barré syndrome. , 1997, The Journal of infectious diseases.

[12]  J. Hillert,et al.  No association with HLA-DR, -DQ or -DP alleles in Guillain-Barré syndrome , 1991, Journal of Neuroimmunology.

[13]  R. Hughes,et al.  HLA antigens in the Guillain-Barré syndrome , 1988, Journal of Neuroimmunology.

[14]  R. Kaslow,et al.  HLA antigens in Guillain‐Barré Syndrome , 1984, Neurology.

[15]  C. Gorodezky,et al.  HLA-DR antigens in Mexican patients with Guillain-Barré syndrome , 1983, Journal of Neuroimmunology.

[16]  G. Macgregor.  FAMILIAL GUILLAIN-BARRÉSYNDROME , 1965 .

[17]  M. Saunders,et al.  Familial Guillain-Barŕe syndrome. , 1965, Lancet.

[18]  M. Blázquez,et al.  [The Guillain-Barré syndrome due to cytomegalovirus in two siblings. Peak-flow meter as the mechanism of transmission]. , 2002, Medicina clinica.

[19]  Walker Ka,et al.  Guillain-Barre syndrome inthree siblings less than 2years old , 1991 .