Calcium signaling as a novel method to optimize the biosynthetic response of chondrocytes to dynamic mechanical loading

[1]  Naveen Chandrashekar,et al.  Hydromechanical stimulator for chondrocyte-seeded constructs in articular cartilage tissue engineering applications , 2013, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

[2]  M. Tse,et al.  The Effect of Moving Point of Contact Stimulation on Chondrocyte Gene Expression and Localization in Tissue Engineered Constructs , 2013, Annals of Biomedical Engineering.

[3]  S. Waldman,et al.  Mechanical stimulation of chondrocyte-agarose hydrogels. , 2012, Journal of visualized experiments : JoVE.

[4]  Walter Herzog,et al.  Mechanically induced calcium signaling in chondrocytes in situ , 2012, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[5]  David Eglin,et al.  Physical Stimulation of Chondrogenic Cells In Vitro: A Review , 2011, Clinical orthopaedics and related research.

[6]  S. Waldman,et al.  The Effect of Intermittent Static Biaxial Tensile Strains on Tissue Engineered Cartilage , 2010, Annals of Biomedical Engineering.

[7]  R. Haut,et al.  Effect of intermittent cyclic preloads on the response of articular cartilage explants to an excessive level of unconfined compression , 2008, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[8]  Michael E. Greenberg,et al.  From Synapse to Nucleus: Calcium-Dependent Gene Transcription in the Control of Synapse Development and Function , 2008, Neuron.

[9]  S. Waldman,et al.  Mechanical vibrations increase the proliferation of articular chondrocytes in high-density culture , 2008, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

[10]  D L Bader,et al.  Cyclic compression of chondrocytes modulates a purinergic calcium signalling pathway in a strain rate‐ and frequency‐dependent manner , 2006, Journal of cellular physiology.

[11]  J. H. Wang,et al.  An Introductory Review of Cell Mechanobiology , 2006, Biomechanics and modeling in mechanobiology.

[12]  D L Bader,et al.  Intracellular mechanics and mechanotransduction associated with chondrocyte deformation during pipette aspiration. , 2006, Biorheology.

[13]  M. Knight,et al.  Activation of chondrocytes calcium signalling by dynamic compression is independent of number of cycles. , 2005, Archives of biochemistry and biophysics.

[14]  S. Mizuno.  A novel method for assessing effects of hydrostatic fluid pressure on intracellular calcium: a study with bovine articular chondrocytes. , 2005, American journal of physiology. Cell physiology.

[15]  S. Waldman,et al.  Long-term intermittent compressive stimulation improves the composition and mechanical properties of tissue-engineered cartilage. , 2004, Tissue engineering.

[16]  Marcy Wong,et al.  The mechanobiology of articular cartilage development and degeneration. , 2004, Clinical orthopaedics and related research.

[17]  M. Knight,et al.  Confocal Analysis of Local and Cellular Strains in Chondrocyte-Agarose Constructs Subjected to Mechanical Shear , 2004, Annals of Biomedical Engineering.

[18]  J. Urban,et al.  The influence and interactions of hydrostatic and osmotic pressures on the intracellular milieu of chondrocytes. , 2004, Biorheology.

[19]  M. Knight,et al.  Mechanical loading of chondrocytes embedded in 3D constructs: in vitro methods for assessment of morphological and metabolic response to compressive strain. , 2004, Methods in molecular medicine.

[20]  Kyriacos A. Athanasiou,et al.  Principles of Cell Mechanics for Cartilage Tissue Engineering , 2004, Annals of Biomedical Engineering.

[21]  Gerard A. Ateshian,et al.  A Paradigm for Functional Tissue Engineering of Articular Cartilage via Applied Physiologic Deformational Loading , 2004, Annals of Biomedical Engineering.

[22]  D. Bader,et al.  Temporal regulation of chondrocyte metabolism in agarose constructs subjected to dynamic compression. , 2003, Archives of biochemistry and biophysics.

[23]  R. Kandel,et al.  Long‐term intermittent shear deformation improves the quality of cartilaginous tissue formed in vitro , 2003, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[24]  D. A. Lee,et al.  Live cell imaging using confocal microscopy induces intracellular calcium transients and cell death. , 2003, American journal of physiology. Cell physiology.

[25]  F. Guilak,et al.  Hypo-osmotic stress induces calcium-dependent actin reorganization in articular chondrocytes. , 2003, Osteoarthritis and cartilage.

[26]  R. Sah,et al.  Biochemical quantification of DNA in human articular and septal cartilage using PicoGreen and Hoechst 33258. , 2002, Osteoarthritis and cartilage.

[27]  J. Hancox,et al.  Effects of cell swelling on intracellular calcium and membrane currents in bovine articular chondrocytes , 2002, Journal of cellular biochemistry.

[28]  D. Burr,et al.  Recovery periods restore mechanosensitivity to dynamically loaded bone. , 2001, The Journal of experimental biology.

[29]  M. Knight,et al.  Mechanical compression influences intracellular Ca2+ signaling in chondrocytes seeded in agarose constructs. , 2001, Journal of applied physiology.

[30]  M. Berridge,et al.  The versatility and universality of calcium signalling , 2000, Nature Reviews Molecular Cell Biology.

[31]  H J Helminen,et al.  Normal and pathological adaptations of articular cartilage to joint loading , 2000, Scandinavian journal of medicine & science in sports.

[32]  G. Lee,et al.  ATP release by mechanically loaded porcine chondrons in pellet culture. , 2000, Arthritis and rheumatism.

[33]  G A Ateshian,et al.  Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels. , 2000, Journal of biomechanical engineering.

[34]  A. Grodzinsky,et al.  Cartilage tissue remodeling in response to mechanical forces. , 2000, Annual review of biomedical engineering.

[35]  R Langer,et al.  Modulation of the mechanical properties of tissue engineered cartilage. , 2000, Biorheology.

[36]  R. Kandel,et al.  Deep Zone Articular Chondrocytes In Vitro Express Genes That Show Specific Changes with Mineralization , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[37]  C. Jacobs,et al.  Mechanisms contributing to fluid‐flow‐induced Ca2+ mobilization in articular chondrocytes , 1999, Journal of cellular physiology.

[38]  C. Rubin,et al.  Mechanically induced calcium waves in articular chondrocytes are inhibited by gadolinium and amiloride , 1999, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[39]  S E Carver,et al.  Increasing extracellular matrix production in regenerating cartilage with intermittent physiological pressure. , 1999, Biotechnology and bioengineering.

[40]  Peter Lipp,et al.  Calcium - a life and death signal , 1998, Nature.

[41]  Y. Umemura,et al.  Five Jumps per Day Increase Bone Mass and Breaking Force in Rats , 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[42]  D L Bader,et al.  Compressive strains at physiological frequencies influence the metabolism of chondrocytes seeded in agarose , 1997, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[43]  B. Hille,et al.  Mitochondrial Participation in the Intracellular Ca2+ Network , 1997, The Journal of cell biology.

[44]  F. Vittur,et al.  Spatial and Temporal Ca2+ Signaling in Articular Chondrocytes , 1995 .

[45]  E B Hunziker,et al.  Mechanical compression modulates matrix biosynthesis in chondrocyte/agarose culture. , 1995, Journal of cell science.

[46]  L E Lanyon,et al.  The success and failure of the adaptive response to functional load-bearing in averting bone fracture. , 1992, Bone.

[47]  J. Lytton,et al.  Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps. , 1991, The Journal of biological chemistry.

[48]  H J Helminen,et al.  Indentation stiffness of young canine knee articular cartilage--influence of strenuous joint loading. , 1990, Journal of biomechanics.

[49]  A. Grodzinsky,et al.  Biosynthetic response of cartilage explants to dynamic compression , 1989, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[50]  I. Kiviranta,et al.  Moderate running exercise augments glycosaminoglycans and thickness of articular cartilage in the knee joint of young beagle dogs , 1988, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[51]  H J Helminen,et al.  Weight bearing controls glycosaminoglycan concentration and articular cartilage thickness in the knee joints of young beagle dogs. , 1987, Arthritis and rheumatism.

[52]  L. Lanyon,et al.  Regulation of bone formation by applied dynamic loads. , 1984, The Journal of bone and joint surgery. American volume.

[53]  B. Caterson,et al.  Changes in the metabolism of the proteoglycans from sheep articular cartilage in response to mechanical stress , 1978 .

[54]  R. Diegelmann,et al.  Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteins. , 1971, Biochemistry.