Immunologic targeting of the cancer stem cell
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[1] Mina J Bissell,et al. Is CD133 a marker of metastatic colon cancer stem cells? , 2008, The Journal of clinical investigation.
[2] A. Strasser,et al. Is tumor growth sustained by rare cancer stem cells or dominant clones? , 2008, Cancer research.
[3] Curt Balch,et al. Identification and characterization of ovarian cancer-initiating cells from primary human tumors. , 2008, Cancer research.
[4] M. Schmitt,et al. Leukemia‐associated antigens as target structures for a specific immunotherapy in chronic myeloid leukemia , 2008, European journal of haematology.
[5] P. Pedrazzoli,et al. Transplantation of allogeneic hematopoietic stem cells: an emerging treatment modality for solid tumors , 2008, Nature Clinical Practice Oncology.
[6] H. Levitsky,et al. The allogeneic effect revisited: exogenous help for endogenous, tumor-specific T cells. , 2008, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[7] Kornelia Polyak,et al. The cancer stem cell hypothesis: in search of definitions, markers, and relevance , 2008, Laboratory Investigation.
[8] D. Neuberg,et al. Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients , 2008, Proceedings of the National Academy of Sciences.
[9] J. Radich,et al. Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is active in patients with imatinib-resistant or -intolerant accelerated-phase chronic myelogenous leukemia. , 2008, Blood.
[10] K. Kinzler,et al. Epitope landscape in breast and colorectal cancer. , 2008, Cancer research.
[11] J. Crowley,et al. Phase III randomized, intergroup trial assessing imatinib mesylate at two dose levels in patients with unresectable or metastatic gastrointestinal stromal tumors expressing the kit receptor tyrosine kinase: S0033. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[12] D. Neuberg,et al. MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma , 2008, Proceedings of the National Academy of Sciences.
[13] Mohamed H. Sayegh,et al. Identification of cells initiating human melanomas , 2008, Nature.
[14] R. Pazdur,et al. Sprycel for Chronic Myeloid Leukemia and Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia Resistant to or Intolerant of Imatinib Mesylate , 2008, Clinical Cancer Research.
[15] J. Chewning,et al. Hierarchy of the human natural killer cell response is determined by class and quantity of inhibitory receptors for self-HLA-B and HLA-C ligands , 2007, The Journal of Immunology.
[16] Z. Rudzki,et al. BCR-ABL Messenger RNA Levels Continue to Decline in Patients with Chronic Phase Chronic Myeloid Leukemia Treated with Imatinib for More Than 5 Years and Approximately Half of All First-Line Treated Patients Have Stable Undetectable BCR-ABL Using Strict Sensitivity Criteria , 2007, Clinical Cancer Research.
[17] K. Rezvani,et al. Leukemia-associated antigen-specific T-cell responses following combined PR1 and WT1 peptide vaccination in patients with myeloid malignancies. , 2007, Blood.
[18] Catherine J. Wu,et al. Proteomics To Identify Novel Immune-Targeted CML Stem Cell Antigens. , 2007 .
[19] K. Bhalla,et al. Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance. , 2007, Blood.
[20] Marcela R. Uribe,et al. Rapid natural killer cell recovery determines outcome after T-cell-depleted HLA-identical stem cell transplantation in patients with myeloid leukemias but not with acute lymphoblastic leukemia , 2007, Leukemia.
[21] D. Douek,et al. Graft-versus-leukemia effects associated with detectable Wilms tumor-1 specific T lymphocytes after allogeneic stem-cell transplantation for acute lymphoblastic leukemia. , 2007, Blood.
[22] C. Sawyers,et al. Sequential ABL kinase inhibitor therapy selects for compound drug-resistant BCR-ABL mutations with altered oncogenic potency. , 2007, The Journal of clinical investigation.
[23] Aleksandar Dakic,et al. Tumor Growth Need Not Be Driven by Rare Cancer Stem Cells , 2007, Science.
[24] K. Dietz,et al. Intensity of HLA class I expression and KIR‐mismatch determine NK‐cell mediated lysis of leukaemic blasts from children with acute lymphatic leukaemia , 2007, British journal of haematology.
[25] J. Radich,et al. Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia after failure of first-line imatinib: a randomized phase 2 trial. , 2007, Blood.
[26] G. Perrone,et al. Alternative BCR/ABL splice variants in Philadelphia chromosome-positive leukemias result in novel tumor-specific fusion proteins that may represent potential targets for immunotherapy approaches. , 2007, Cancer research.
[27] S. Vogel,et al. Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming , 2007, Proceedings of the National Academy of Sciences.
[28] R. Larson,et al. Dasatinib induces significant hematologic and cytogenetic responses in patients with imatinib-resistant or -intolerant chronic myeloid leukemia in accelerated phase. , 2007, Blood.
[29] J. Powell,et al. Factors governing the activation of adoptively transferred donor T cells infused after allogeneic bone marrow transplantation in the mouse. , 2007, Blood.
[30] C. Eaves,et al. Instability of BCR-ABL gene in primary and cultured chronic myeloid leukemia stem cells. , 2007, Journal of the National Cancer Institute.
[31] Alexander Brawanski,et al. CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. , 2007, Cancer research.
[32] T. Holyoake,et al. Nilotinib exerts equipotent antiproliferative effects to imatinib and does not induce apoptosis in CD34+ CML cells. , 2007, Blood.
[33] James McCluskey,et al. More than one reason to rethink the use of peptides in vaccine design , 2007, Nature Reviews Drug Discovery.
[34] J. Crowley,et al. Frequent and specific immunity to the embryonal stem cell–associated antigen SOX2 in patients with monoclonal gammopathy , 2007, The Journal of experimental medicine.
[35] M. Baccarani,et al. Dasatinib induces complete hematologic and cytogenetic responses in patients with imatinib-resistant or -intolerant chronic myeloid leukemia in blast crisis. , 2007, Blood.
[36] R. Beroukhim,et al. Molecular definition of breast tumor heterogeneity. , 2007, Cancer cell.
[37] E. Birney,et al. Patterns of somatic mutation in human cancer genomes , 2007, Nature.
[38] S. Gabriel,et al. High-throughput oncogene mutation profiling in human cancer , 2007, Nature Genetics.
[39] J. Ritz,et al. Beyond HLA: the significance of genomic variation for allogeneic hematopoietic stem cell transplantation. , 2007, Blood.
[40] G. Parmiani,et al. Unique Human Tumor Antigens: Immunobiology and Use in Clinical Trials1 , 2007, The Journal of Immunology.
[41] D. Haber,et al. Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[42] G. Sherlock,et al. The prognostic role of a gene signature from tumorigenic breast-cancer cells. , 2007, The New England journal of medicine.
[43] Louis Gaboury,et al. SP analysis may be used to identify cancer stem cell populations. , 2006, Experimental cell research.
[44] F. Menghi,et al. Neurospheres enriched in cancer stem-like cells are highly effective in eliciting a dendritic cell-mediated immune response against malignant gliomas. , 2006, Cancer research.
[45] G. Parmigiani,et al. The Consensus Coding Sequences of Human Breast and Colorectal Cancers , 2006, Science.
[46] Irving L Weissman,et al. Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells. , 2006, Cancer research.
[47] J. Dick,et al. Targeting of CD44 eradicates human acute myeloid leukemic stem cells , 2006, Nature Medicine.
[48] A. Anichini,et al. Unique Tumor Antigens: Evidence for Immune Control of Genome Integrity and Immunogenic Targets for T Cell–Mediated Patient-Specific Immunotherapy , 2006, Clinical Cancer Research.
[49] J. Ritz,et al. Rituximab for steroid-refractory chronic graft-versus-host disease. , 2006, Blood.
[50] S. Rosenberg,et al. Intrapatient Dose Escalation of Anti–CTLA-4 Antibody in Patients With Metastatic Melanoma , 2006, Journal of immunotherapy.
[51] F. Hodi,et al. Therapy-induced antibodies to MHC class I chain-related protein A antagonize immune suppression and stimulate antitumor cytotoxicity. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[52] M. Copland,et al. Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction. , 2006, Blood.
[53] A. Feldman,et al. Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[54] A. Goldhirsch,et al. Breast cancer vaccines: a clinical reality or fairy tale? , 2006, Annals of oncology : official journal of the European Society for Medical Oncology.
[55] M. Little,et al. A Side Order of Stem Cells: The SP Phenotype , 2006, Stem cells.
[56] B. Comin-Anduix,et al. Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[57] N. Maitland,et al. Prospective identification of tumorigenic prostate cancer stem cells. , 2005, Cancer research.
[58] J. Falkenburg,et al. Up-regulated expression in nonhematopoietic tissues of the BCL2A1-derived minor histocompatibility antigens in response to inflammatory cytokines: relevance for allogeneic immunotherapy of leukemia. , 2005, Blood.
[59] P. Dalerba,et al. Identification of pancreatic cancer stem cells. , 2006, Cancer research.
[60] S. Rosenberg,et al. Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[61] T. Uchiyama,et al. Identification of APOBEC3B as a potential target for the graft‐versus‐lymphoma effect by SEREX in a patient with mantle cell lymphoma , 2005, British journal of haematology.
[62] M. Martelli,et al. The impact of donor natural killer cell alloreactivity on allogeneic hematopoietic transplantation. , 2005, Transplant immunology.
[63] F. Pijpers,et al. Therapeutic cancer vaccines , 2005, Nature Reviews Drug Discovery.
[64] M. Horowitz,et al. Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes. , 2005, Blood.
[65] J. Kutok,et al. Graft-versus-Leukemia Target Antigens in Chronic Myelogenous Leukemia Are Expressed on Myeloid Progenitor Cells , 2005, Clinical Cancer Research.
[66] H. Einsele,et al. Outcomes for reduced-intensity allogeneic transplantation for multiple myeloma: an analysis of prognostic factors from the Chronic Leukaemia Working Party of the EBMT. , 2005, Blood.
[67] Bingyan Wu,et al. Graft-versus-tumor response in patients with multiple myeloma is associated with antibody response to BCMA, a plasma-cell membrane receptor. , 2005, Blood.
[68] G. Giaccone,et al. Epidermal growth factor receptor inhibitors in the treatment of non-small-cell lung cancer. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[69] M. Martelli,et al. Natural killer cell alloreactivity for leukemia therapy. , 2005, Journal of immunotherapy.
[70] C. Le,et al. Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer. , 2005, Blood.
[71] L. Hambach,et al. Immunotherapy of cancer through targeting of minor histocompatibility antigens. , 2005, Current opinion in immunology.
[72] K. Hsu,et al. Natural killer cell receptors: regulating innate immune responses to hematologic malignancy. , 2005, Seminars in hematology.
[73] S. Groshen,et al. Autoimmunity in a phase I trial of a fully human anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and Montanide ISA 51 for patients with resected stages III and IV melanoma. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[74] E. Jaffee,et al. Diverse CD8+ T-cell responses to renal cell carcinoma antigens in patients treated with an autologous granulocyte-macrophage colony-stimulating factor gene-transduced renal tumor cell vaccine. , 2005, Cancer research.
[75] F. Vély,et al. Coordination of activating and inhibitory signals in natural killer cells. , 2005, Molecular immunology.
[76] C. Craddock,et al. Outcomes after alemtuzumab-containing reduced-intensity allogeneic transplantation regimen for relapsed and refractory non-Hodgkin lymphoma. , 2004, Blood.
[77] E. Warren,et al. A Novel HLA-A*3303-Restricted Minor Histocompatibility Antigen Encoded by an Unconventional Open Reading Frame of Human TMSB4Y Gene1 , 2004, The Journal of Immunology.
[78] F. Giles,et al. The Spermatozoa Protein, SLLP1, Is a Novel Cancer–Testis Antigen in Hematologic Malignancies , 2004, Clinical Cancer Research.
[79] K. Kuzushima,et al. Expansion and activation of minor histocompatibility antigen HY-specific T cells associated with graft-versus-leukemia response , 2004, Bone Marrow Transplantation.
[80] J. Gribben,et al. Comparative outcome of nonmyeloablative and myeloablative allogeneic hematopoietic cell transplantation for patients older than 50 years of age. , 2004, Blood.
[81] T. Kyo,et al. Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[82] Laurie E Ailles,et al. Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. , 2004, The New England journal of medicine.
[83] S. Riddell,et al. Molecules and mechanisms of the graft-versus-leukaemia effect , 2004, Nature Reviews Cancer.
[84] R. Verdijk,et al. Pregnancy induces minor histocompatibility antigen-specific cytotoxic T cells: implications for stem cell transplantation and immunotherapy. , 2004, Blood.
[85] W. Lehmacher,et al. Adjuvant autologous renal tumour cell vaccine and risk of tumour progression in patients with renal-cell carcinoma after radical nephrectomy: phase III, randomised controlled trial , 2004, The Lancet.
[86] Catherine J. Wu,et al. Antibody responses to H-Y minor histocompatibility antigens correlate with chronic graft-versus-host disease and disease remission. , 2004, Blood.
[87] D. Scheinberg,et al. A multivalent bcr-abl fusion peptide vaccination trial in patients with chronic myeloid leukemia. , 2004, Blood.
[88] Mads Hald Andersen,et al. Identification of Novel Survivin-Derived CTL Epitopes with Different HLA-A-Restriction Profiles , 2004, Cancer biology & therapy.
[89] L. Moretta,et al. Unravelling natural killer cell function: triggering and inhibitory human NK receptors , 2004, The EMBO journal.
[90] Catherine J. Wu,et al. Complete response to donor lymphocyte infusion in multiple myeloma is associated with antibody responses to highly expressed antigens. , 2004, Blood.
[91] J. Raemaekers,et al. Graft-versus-lymphoma effect of donor lymphocyte infusion in indolent lymphomas relapsed after allogeneic stem cell transplantation , 2003, Bone Marrow Transplantation.
[92] Irving L Weissman,et al. Biology of hematopoietic stem cells and progenitors: implications for clinical application. , 2003, Annual review of immunology.
[93] G. Hortobagyi,et al. Rapid induction of complete donor chimerism by the use of a reduced-intensity conditioning regimen composed of fludarabine and melphalan in allogeneic stem cell transplantation for metastatic solid tumors. , 2003, Blood.
[94] Susan Branford,et al. Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia. , 2003, The New England journal of medicine.
[95] Irving L. Weissman,et al. Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics? , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[96] Cynthia Hawkins,et al. Identification of a cancer stem cell in human brain tumors. , 2003, Cancer research.
[97] E. Warren,et al. The graft versus leukemia response after allogeneic hematopoietic stem cell transplantation. , 2003, Blood reviews.
[98] M. Boccadoro,et al. Molecular remission after myeloablative allogeneic stem cell transplantation predicts a better relapse-free survival in patients with multiple myeloma. , 2003, Blood.
[99] D. Neuberg,et al. Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[100] B. Abbott. ABCG2 (BCRP) expression in normal and malignant hematopoietic cells , 2003, Hematological oncology.
[101] T. Mutis,et al. Identification of HLA class II-restricted H-Y-specific T-helper epitope evoking CD4+ T-helper cells in H-Y-mismatched transplantation , 2003, The Lancet.
[102] M. Becker,et al. Treatment of chronic graft-versus-host disease with anti-CD20 chimeric monoclonal antibody. , 2003, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[103] J. Shabanowitz,et al. The minor Histocompatibility antigen HA-3 arises from differential proteasome-mediated cleavage of the lymphoid blast crisis (Lbc) oncoprotein , 2003 .
[104] E. Simpson,et al. Multiparity induces priming to male-specific minor histocompatibility antigen, HY, in mice and humans. , 2003, Blood.
[105] Thomas A. Davis,et al. Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[106] T. Naoe,et al. Identification of a Polymorphic Gene, BCL2A1, Encoding Two Novel Hematopoietic Lineage-specific Minor Histocompatibility Antigens , 2003, The Journal of experimental medicine.
[107] E. Warren,et al. A Human Minor Histocompatibility Antigen Resulting from Differential Expression due to a Gene Deletion , 2003, The Journal of experimental medicine.
[108] Donna Niedzwiecki,et al. Immunological and clinical responses in metastatic renal cancer patients vaccinated with tumor RNA-transfected dendritic cells. , 2003, Cancer research.
[109] Thomas Davis,et al. Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[110] Francisco Cervantes,et al. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. , 2003, The New England journal of medicine.
[111] S. Morrison,et al. Prospective identification of tumorigenic breast cancer cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[112] Ken Jung,et al. Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[113] K. Krohn,et al. Emergence of clonal cytogenetic abnormalities in Ph- cells in some CML patients in cytogenetic remission to imatinib but restoration of polyclonal hematopoiesis in the majority. , 2003, Blood.
[114] D. Pardoll,et al. Successful therapy of metastatic cancer using tumor vaccines in mixed allogeneic bone marrow chimeras. , 2003, Blood.
[115] P. Kantoff,et al. CML28 is a broadly immunogenic antigen, which is overexpressed in tumor cells. , 2002, Cancer research.
[116] J. Kuriyan,et al. Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. , 2002, Cancer cell.
[117] Claude Preudhomme,et al. Several types of mutations of the Abl gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment. , 2002, Blood.
[118] C. Sawyers,et al. Clinical resistance to the kinase inhibitor STI-571 in chronic myeloid leukemia by mutation of Tyr-253 in the Abl kinase domain P-loop , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[119] Catherine J. Wu,et al. Immunologic effects of prophylactic donor lymphocyte infusion after allogeneic marrow transplantation for multiple myeloma. , 2002, Blood.
[120] R. Larson,et al. Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study. , 2002, Blood.
[121] N. Hosen,et al. patients with hematopoietic malignancies product in WT 1 Humoral immune responses against Wilms tumor gene , 2002 .
[122] R. Herrmann,et al. High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance. , 2002, Blood.
[123] J. Drijfhout,et al. The DBY gene codes for an HLA-DQ5-restricted human male-specific minor histocompatibility antigen involved in graft-versus-host disease. , 2002, Blood.
[124] Katia Perruccio,et al. Effectiveness of Donor Natural Killer Cell Alloreactivity in Mismatched Hematopoietic Transplants , 2002, Science.
[125] S. Fujita,et al. Identification of a novel WT1‐derived peptide which induces human leucocyte antigen‐A24‐restricted anti‐leukaemia cytotoxic T lymphocytes , 2002, British journal of haematology.
[126] M. Baccarani,et al. Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. , 2002, The New England journal of medicine.
[127] G. Dranoff,et al. Donor leukocyte infusion from immunized donors increases tumor vaccine efficacy after allogeneic bone marrow transplantation. , 2002, Cancer research.
[128] S. Amigorena,et al. Fcγ Receptors and Cross-Presentation in Dendritic Cells , 2002, The Journal of experimental medicine.
[129] M. Dhodapkar,et al. Antitumor Monoclonal Antibodies Enhance Cross-Presentation of Cellular Antigens and the Generation of Myeloma-specific Killer T Cells by Dendritic Cells , 2002, The Journal of experimental medicine.
[130] M. Talpaz,et al. Long-Term follow-up of recipients of CD8-depleted donor lymphocyte infusions for the treatment of chronic myelogenous leukemia relapsing after allogeneic progenitor cell transplantation. , 2001, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[131] J. Shabanowitz,et al. The HA-2 Minor Histocompatibility Antigen Is Derived from a Diallelic Gene Encoding a Novel Human Class I Myosin Protein , 2001, The Journal of Immunology.
[132] P. N. Rao,et al. Clinical Resistance to STI-571 Cancer Therapy Caused by BCR-ABL Gene Mutation or Amplification , 2001, Science.
[133] P. Kantoff,et al. CML66, a broadly immunogenic tumor antigen, elicits a humoral immune response associated with remission of chronic myelogenous leukemia , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[134] J. Radich,et al. Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus-tumor effects. , 2001, Blood.
[135] C. Sawyers,et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. , 2001, The New England journal of medicine.
[136] C. Sawyers,et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. , 2001, The New England journal of medicine.
[137] J. Esteve,et al. Stem cell transplantation for chronic lymphocytic leukemia: different outcome after autologous and allogeneic transplantation and correlation with minimal residual disease status , 2001, Leukemia.
[138] L. Carter,et al. WT1-specific serum antibodies in patients with leukemia. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.
[139] J. Shabanowitz,et al. The Immunogenicity of a New Human Minor Histocompatibility Antigen Results from Differential Antigen Processing , 2001, The Journal of experimental medicine.
[140] J. Falkenburg,et al. UTY gene codes for an HLA-B60-restricted human male-specific minor histocompatibility antigen involved in stem cell graft rejection: characterization of the critical polymorphic amino acid residues for T-cell recognition. , 2000, Blood.
[141] P. Seeburg,et al. Structural mechanism for STI-571 inhibition of abelson tyrosine kinase. , 2000, Science.
[142] W. Linehan,et al. Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation. , 2000, The New England journal of medicine.
[143] D. Neuberg,et al. Detection of a potent humoral response associated with immune-induced remission of chronic myelogenous leukemia. , 2000, The Journal of clinical investigation.
[144] Mark M. Davis,et al. Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia , 2000, Nature Medicine.
[145] C. Mullen,et al. Immunization of allogeneic bone marrow transplant recipients with tumor cell vaccines enhances graft-versus-tumor activity without exacerbating graft-versus-host disease. , 2000, Blood.
[146] J. Goldman,et al. Selective elimination of leukemic CD34(+) progenitor cells by cytotoxic T lymphocytes specific for WT1. , 2000, Blood.
[147] J. Falkenburg,et al. DFFRY codes for a new human male-specific minor transplantation antigen involved in bone marrow graft rejection. , 2000, Blood.
[148] H. Sugiyama,et al. Human cytotoxic T-lymphocyte responses specific for peptides of the wild-type Wilms' tumor gene (WT1 ) product , 2000, Immunogenetics.
[149] J. Shabanowitz,et al. Cutting edge: the HLA-A*0101-restricted HY minor histocompatibility antigen originates from DFFRY and contains a cysteinylated cysteine residue as identified by a novel mass spectrometric technique. , 1999, Journal of immunology.
[150] A. Gratwohl,et al. Graft-versus-myeloma after withdrawal of immunosuppression following allogeneic peripheral stem cell transplantation , 1999, Bone Marrow Transplantation.
[151] W. M. Smit,et al. Complete remission of accelerated phase chronic myeloid leukemia by treatment with leukemia-reactive cytotoxic T lymphocytes. , 1999, Blood.
[152] J. Connors,et al. Long-term follow-up of patients who achieved complete remission after donor leukocyte infusions. , 1999, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[153] J. Dick,et al. CD8(+) minor histocompatibility antigen-specific cytotoxic T lymphocyte clones eliminate human acute myeloid leukemia stem cells. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[154] Z. Estrov,et al. The biology of chronic myeloid leukemia. , 1999, The New England journal of medicine.
[155] A. Tosti,et al. Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation. , 1999, Blood.
[156] S. H. Lim,et al. Prevalence of antibodies against proteins derived from leukemia cells in patients with chronic myeloid leukemia. , 1998, Blood.
[157] D. Neuberg,et al. Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[158] N. Ueno,et al. Transplant-lite: induction of graft-versus-malignancy using fludarabine-based nonablative chemotherapy and allogeneic blood progenitor-cell transplantation as treatment for lymphoid malignancies. , 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[159] D. Neuberg,et al. Toxicity and efficacy of defined doses of CD4(+) donor lymphocytes for treatment of relapse after allogeneic bone marrow transplant. , 1998, Blood.
[160] J. Falkenburg,et al. Generation of leukemia-reactive cytotoxic T lymphocytes from HLA-identical donors of patients with chronic myeloid leukemia using modifications of a limiting dilution assay , 1998, Bone Marrow Transplantation.
[161] J. Shabanowitz,et al. The minor histocompatibility antigen HA-1: a diallelic gene with a single amino acid polymorphism. , 1998, Science.
[162] J. Cornelissen,et al. Donor leukocyte infusions are effective in relapsed multiple myeloma after allogeneic bone marrow transplantation. , 1997, Blood.
[163] J. Melo,et al. The tyrosine kinase inhibitor CGP57148B selectively inhibits the growth of BCR-ABL-positive cells. , 1997, Blood.
[164] M. Pfreundschuh,et al. Serological identification of human tumor antigens. , 1997, Current opinion in immunology.
[165] J. Dick,et al. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell , 1997, Nature Medicine.
[166] A. Agulnik,et al. The HLA-A*0201-restricted H-Y antigen contains a posttranslationally modified cysteine that significantly affects T cell recognition. , 1997, Immunity.
[167] Robert H. Collins,et al. Donor leukocyte infusions in 140 patients with relapsed malignancy after allogeneic bone marrow transplantation. , 1997, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[168] M. Labopin,et al. Graft-versus-leukemia effect in allogeneic marrow transplant recipients with acute leukemia is maintained using cyclosporin A combined with methotrexate as prophylaxis. Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation. , 1996, Bone marrow transplantation.
[169] M. Andreeff,et al. Graft-versus-leukemia effect after allogeneic bone marrow transplantation for chronic lymphocytic leukemia. , 1996, Bone marrow transplantation.
[170] Jürg Zimmermann,et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells , 1996, Nature Medicine.
[171] B. Barlogie,et al. Graft-versus-myeloma effect: proof of principle. , 1996, Blood.
[172] A. Agulnik,et al. Human H-Y: a male-specific histocompatibility antigen derived from the SMCY protein. , 1995, Science.
[173] A Ferrant,et al. Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients. , 1995, Blood.
[174] C. Perreault,et al. Distinct patterns of minimal residual disease associated with graft-versus-host disease after allogeneic bone marrow transplantation for chronic myelogenous leukemia. , 1995, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[175] J. Sidney,et al. Specific binding of leukemia oncogene fusion protein peptides to HLA class I molecules. , 1995, Blood.
[176] J. Goldman,et al. Relapse of chronic myeloid leukemia after allogeneic bone marrow transplant: the case for giving donor leukocyte transfusions before the onset of hematologic relapse. , 1994, Blood.
[177] A. Rimm,et al. Identical-Twin Bone Marrow Transplants for Leukemia , 1994, Annals of Internal Medicine.
[178] M. Caligiuri,et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice , 1994, Nature.
[179] D. Page,et al. The human Y chromosome: overlapping DNA clones spanning the euchromatic region. , 1992, Science.
[180] R. Collins,et al. Hematologic relapse of chronic myelogenous leukemia following allogeneic bone marrow transplantation: apparent graft-versus-leukemia effect following abrupt discontinuation of immunosuppression. , 1992, Bone marrow transplantation.
[181] R. Truitt,et al. Contribution of CD4+ and CD8+ T cells to graft-versus-host disease and graft-versus-leukemia reactivity after transplantation of MHC-compatible bone marrow. , 1991, Bone marrow transplantation.
[182] S. Piantadosi,et al. Evidence of a graft-versus-lymphoma effect associated with allogeneic bone marrow transplantation. , 1991, Blood.
[183] S. Feig,et al. Selective depletion of CD8+ T lymphocytes for prevention of graft-versus-host disease after allogeneic bone marrow transplantation. , 1990, Blood.
[184] L. Barnett,et al. Anti-leukemia potential of interleukin-2 activated natural killer cells after bone marrow transplantation for chronic myelogenous leukemia. , 1990, Blood.
[185] M. Pepe,et al. Previous donor pregnancy as a risk factor for acute graft‐versus‐host disease in patients with aplastic anaemia treated by allogeneic marrow transplantation , 1990, British journal of haematology.
[186] A. Rimm,et al. Graft-versus-leukemia reactions after bone marrow transplantation. , 1990, Blood.
[187] R Storb,et al. Influence of acute and chronic graft-versus-host disease on relapse and survival after bone marrow transplantation from HLA-identical siblings as treatment of acute and chronic leukemia. , 1989, Blood.
[188] K. Sullivan,et al. HLA-identical marrow transplantation during accelerated-phase chronic myelogenous leukemia: analysis of survival and remission duration. , 1988, Blood.
[189] R. Hoffmann,et al. Bone marrow transplantation for chronic myelogenous leukemia in chronic phase. Increased risk for relapse associated with T-cell depletion. , 1988 .
[190] A. Butturini,et al. Graft-versus-leukemia following bone marrow transplantation. , 1987, Bone marrow transplantation.
[191] A I Goldman,et al. Allogeneic bone marrow transplantation for acute lymphoblastic leukemia in remission: prolonged survival associated with acute graft-versus-host disease. , 1987, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[192] J. Biggs,et al. Female marrow donors increase the risk of acute graft‐versus‐host disease: effect of donor age and parity and analysis of cell subpopulations in the donor marrow inoculum , 1986, British journal of haematology.
[193] K. Anderson,et al. Characterization of natural killer cells with antileukemia activity following allogeneic bone marrow transplantation. , 1986, Blood.
[194] H. Koeffler,et al. Chronic Myelocytic Leukaemia: a Pluripotent Haemopoietic Cell is Involved in the Malignant Clone , 1981, British journal of haematology.
[195] K. Sullivan,et al. Antileukemic effect of chronic graft-versus-host disease: contribution to improved survival after allogeneic marrow transplantation. , 1981, The New England journal of medicine.
[196] V. Najfeld,et al. Involvement of the B-lymphoid system in chronic myelogenous leukaemia , 1980, Nature.
[197] J. Adamson,et al. Restoration of nonclonal hematopoiesis in chronic myelogenous leukemia (CML) following a chemotherapy-induced loss of the Ph1 chromosome. , 1980, Blood.
[198] A. Levine,et al. Chronic myelocytic leukemia: eosinophils involved in the malignant clone. , 1980, Blood.
[199] R. Storb,et al. Antileukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow grafts. , 1979, The New England journal of medicine.
[200] D. Peakman,et al. REMISSION OF RELAPSED LEUKÆMIA DURING A GRAFT-VERSUS-HOST REACTION A "GRAFT-VERSUS-LEUKÆMIA REACTION" IN MAN? , 1978, The Lancet.
[201] T. Papayannopoulou,et al. Chronic myelocytic leukemia: clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage. , 1977, The American journal of medicine.
[202] G. Saglio,et al. Harmonization of BCR-ABL mRNA quantification using a uniform multifunctional control plasmid in 37 international laboratories , 2008, Leukemia.
[203] R M Stone,et al. Dasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukemia in chronic phase with resistance or intolerance to imatinib , 2008, Leukemia.
[204] M. Gordon. Enterocolitis in Patients With Cancer After Antibody Blockade of Cytotoxic T-Lymphocyte–Associated Antigen 4 , 2008 .
[205] M. Baccarani,et al. Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of imatinib therapy , 2007 .
[206] Yao-Tseng Chen,et al. NY-ESO-1: review of an immunogenic tumor antigen. , 2006, Advances in cancer research.
[207] F. Appelbaum,et al. Female donors contribute to a selective graft-versus-leukemia effect in male recipients of HLA-matched, related hematopoietic stem cell transplants. , 2004, Blood.
[208] J. Ritz,et al. Antibody response to DBY minor histocompatibility antigen is induced after allogeneic stem cell transplantation and in healthy female donors. , 2004, Blood.
[209] M. Slovak,et al. Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment. , 2003, Blood.
[210] T. Mutis,et al. Targeting alloreactive T cells to hematopoietic system specific minor histocompatibility antigens for cellular immunotherapy of hematological malignancies after stem cell transplantation. , 2002, Annals of hematology.
[211] Sante Tura,et al. A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias. , 2002, Blood.
[212] T. Holyoake,et al. Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro. , 2002, Blood.
[213] B. Druker,et al. Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy , 2002, Leukemia.
[214] T. Schumacher,et al. In situ dissection of the graft-versus-host activities of cytotoxic T cells specific for minor histocompatibility antigens , 2002, Nature Medicine.
[215] M. Kaplan,et al. Identification of HLA-A2-restricted CD8(+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendritic cells. , 2002, The Journal of experimental medicine.
[216] H. V. van Houwelingen,et al. Female donors influence transplant-related mortality and relapse incidence in male recipients of sibling blood and marrow transplants. , 2001, The hematology journal : the official journal of the European Haematology Association.
[217] G. Saglio,et al. Persisting molecular remission ten years after donor lymphocyte infusion for hematologic relapse in chronic myeloid leukemia. , 2001, Haematologica.
[218] C. Craddock,et al. Durability of responses following donor lymphocyte infusions for patients who relapse after allogeneic stem cell transplantation for chronic myeloid leukemia. , 2000, Blood.
[219] A. Barrett,et al. Association of natural killer cell immune recovery with a graft-versus-leukemia effect independent of graft-versus-host disease following allogeneic bone marrow transplantation , 1997, Annals of Hematology.
[220] T. Meyer,et al. Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative. , 1996, Cancer research.
[221] J. Ritz,et al. Persistence of myeloid progenitor cells expressing BCR-ABL mRNA after allogeneic bone marrow transplantation for chronic myelogenous leukemia. , 1994, Blood.
[222] I. Bernstein,et al. Differences in the frequency of normal and clonal precursors of colony-forming cells in chronic myelogenous leukemia and acute myelogenous leukemia. , 1992, Blood.
[223] W. Wilmanns,et al. Donor leukocyte transfusions for treatment of recurrent chronic myelogenous leukemia in marrow transplant patients. , 1990, Blood.
[224] K. Sullivan,et al. Graft versus leukemia effect in man: the relapse rate of acute leukemia is lower after allogeneic than after syngeneic marrow transplantation. , 1987, Progress in clinical and biological research.
[225] J. Singer,et al. Chronic myelocytic leukemia (CML): failure to detect residual normal committed stem cells in vitro. , 1979, Blood.
[226] D. Peakman,et al. Remission of relapsed leukaemia during a graft-versus-host reaction. A "graft-versus-leukaemia reaction" in man? , 1978, Lancet.