A Case of Bacteremia Due to Microbacterium oleivorans Identified by 16S rRNA Sequencing Analysis

Microbacterium oleivorans is a gram-positive, coryneform rod bacterium. The pathogenic potential of the Microbacterium species has recently been reported to be increasing. Microbacterium comprises approximately 50 species. The differences in regards to the biochemical characteristics of Microbacterium species are unclear, and is why molecular investigations (e.g., using 16S rRNA gene sequencing) are the best method to identify the species. We report a case of bacteremia that was caused by Microbacterium oleivorans in a 4-year-old boy, who had no specific medical history. This represents the first report of M. oleivorans bacteremia in Korea. (Korean J Clin Microbiol 2012;15:110-113)

[1]  R. Hill,et al.  Central venous catheter-related bacteraemia due to Microbacterium paraoxydans in a patient with no significant immunodeficiency , 2010, Journal of Clinical Pathology.

[2]  C. Ki,et al.  Catheter-related Bacteremia due to Microbacterium oxydans Identified by 16S rRNA Sequencing Analysis and Biochemical Characteristics , 2010 .

[3]  S. Suh,et al.  Central Venous Catheter-Related Microbacterium Bacteremia Identified by 16S ribosomal RNA Gene Sequencing , 2009 .

[4]  G. Funke,et al.  Identities of Microbacterium spp. Encountered in Human Clinical Specimens , 2008, Journal of Clinical Microbiology.

[5]  R. Hayden,et al.  Infections Caused by Coryneform Bacteria in Pediatric Oncology Patients , 2008, The Pediatric infectious disease journal.

[6]  N. Pace,et al.  Interpretive criteria for identification of bacteria and fungi by DNA target sequencing; approved guideline , 2008 .

[7]  S. Pounds,et al.  Identification of Clinical Coryneform Bacterial Isolates: Comparison of Biochemical Methods and Sequence Analysis of 16S rRNA and rpoB Genes , 2007, Journal of Clinical Microbiology.

[8]  K. Ko,et al.  A new Microbacterium species isolated from the blood of a patient with fever: Microbacterium pyrexiae sp. nov. , 2007, Diagnostic microbiology and infectious disease.

[9]  P. Schumann,et al.  Microbacterium oleivorans sp. nov. and Microbacterium hydrocarbonoxydans sp. nov., novel crude-oil-degrading Gram-positive bacteria. , 2005, International journal of systematic and evolutionary microbiology.

[10]  B. Y. Hwang,et al.  A case of native valve infective endocarditis caused by Microbacterium species , 2004 .

[11]  M. Delmée,et al.  Bacteremia Due to a Novel Microbacterium Species in a Patient with Leukemia and Description of Microbacteriumparaoxydans sp. nov , 2003, Journal of Clinical Microbiology.

[12]  P. Woo,et al.  Catheter-Related Microbacterium Bacteremia Identified by 16S rRNA Gene Sequencing , 2002, Journal of Clinical Microbiology.

[13]  M. Arduino,et al.  Nosocomial outbreak of Microbacterium species bacteremia among cancer patients. , 2001, The Journal of infectious diseases.

[14]  P. Lawson,et al.  Aureobacterium resistens sp. nov., exhibiting vancomycin resistance and teicoplanin susceptibility. , 1998, FEMS microbiology letters.

[15]  Ellen Jo Baron,et al.  Manual of clinical microbiology , 1975 .

[16]  Hal B. Jenson,et al.  Nelson Textbook of Pediatrics , 1965 .