Ketogenic diet alleviates brain iron deposition and cognitive dysfunction via Nrf2-mediated ferroptosis pathway in APP/PS1 mouse
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Rui Yang | Guohui Jiang | Dazhang Bai | Ya-Li Qin | Li Zhao | Jia Li | M. Tang | Ming Zhang
[1] Jinglin Zhao,et al. Ketogenic diet and calorie-restricted diet attenuate ischemic brain injury via UBR4 and downstream CamkⅡ/TAK1/JNK signaling , 2023, Journal of Functional Foods.
[2] M. Janahmadi,et al. Role of amyloid beta (25-35) neurotoxicity in the ferroptosis and necroptosis as modalities of regulated cell death in Alzheimer's Disease. , 2022, Neurotoxicology.
[3] Yuan Zhang,et al. Iron dyshomeostasis and ferroptosis in Alzheimer’s disease: Molecular mechanisms of cell death and novel therapeutic drugs and targets for AD , 2022, Frontiers in Pharmacology.
[4] Ye Tao,et al. Ketogenic Diet: An Effective Treatment Approach for Neurodegenerative Diseases , 2022, Current neuropharmacology.
[5] Anonymous,et al. 2022 Alzheimer's disease facts and figures , 2022, Alzheimer's & dementia : the journal of the Alzheimer's Association.
[6] L. Baum,et al. Effects of Deferasirox in Alzheimer’s Disease and Tauopathy Animal Models , 2022, Biomolecules.
[7] G. Chen,et al. Identification of Ferroptosis-Related Genes in Alzheimer’s Disease Based on Bioinformatic Analysis , 2022, Frontiers in Neuroscience.
[8] M. Murakami,et al. Molecular Mechanisms Underlying the Bioactive Properties of a Ketogenic Diet , 2022, Nutrients.
[9] H. Qin,et al. Ketogenic diet for human diseases: the underlying mechanisms and potential for clinical implementations , 2022, Signal Transduction and Targeted Therapy.
[10] Lin F. Yang,et al. Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019 , 2022, The Lancet. Public health.
[11] X. Deng,et al. Ketogenic diet ameliorates cognitive impairment and neuroinflammation in a mouse model of Alzheimer’s disease , 2021, CNS neuroscience & therapeutics.
[12] H. Kolb,et al. Ketone bodies: from enemy to friend and guardian angel , 2021, BMC Medicine.
[13] Xuejiao Chang,et al. Iron Homeostasis Disorder and Alzheimer’s Disease , 2021, International journal of molecular sciences.
[14] F. Mirzaei,et al. Deferoxamine preconditioning enhances the protective effects of stem cells in streptozotocin-induced Alzheimer's disease. , 2021, Life sciences.
[15] Ling-Qiang Zhu,et al. Ferroptosis, a Potential Therapeutic Target in Alzheimer’s Disease , 2021, Frontiers in Cell and Developmental Biology.
[16] Lan Zhang,et al. Tetrahydroxy stilbene glycoside ameliorates Alzheimer's disease in APP/PS1 mice via glutathione peroxidase related ferroptosis. , 2021, International immunopharmacology.
[17] A. Ünalp,et al. The effect of ketogenic diet on serum lipid concentrations in children with medication resistant epilepsy , 2021, Seizure.
[18] Yanxin Shen,et al. The Potential Role of Ferroptosis in Alzheimer's Disease. , 2021, Journal of Alzheimer's disease : JAD.
[19] A. Belaidi,et al. Ferroptosis: mechanisms and links with diseases , 2021, Signal Transduction and Targeted Therapy.
[20] Junxia Xie,et al. New Insights into the Role of Ferritin in Iron Homeostasis and Neurodegenerative Diseases , 2021, Molecular Neurobiology.
[21] A. Bianco,et al. Effects of Two Months of Very Low Carbohydrate Ketogenic Diet on Body Composition, Muscle Strength, Muscle Area, and Blood Parameters in Competitive Natural Body Builders , 2021, Nutrients.
[22] J. Schneider,et al. Regional brain iron associated with deterioration in Alzheimer's disease: A large cohort study and theoretical significance , 2021, Alzheimer's & dementia : the journal of the Alzheimer's Association.
[23] P. Nelson,et al. Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease , 2021, Cell Death & Differentiation.
[24] T. Fulop,et al. The effect of a 6-month ketogenic medium-chain triglyceride supplement on plasma cardiometabolic and inflammatory markers in mild cognitive impairment. , 2020, Prostaglandins, leukotrienes, and essential fatty acids.
[25] W. Chen,et al. Ferritin reduction is essential for cerebral ischemia-induced hippocampal neuronal death through p53/SLC7A11-mediated ferroptosis , 2020, Brain Research.
[26] P. Edison,et al. Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here? , 2020, Nature Reviews Neurology.
[27] S. Bydlowski,et al. Ferroptosis Mechanisms Involved in Neurodegenerative Diseases , 2020, International journal of molecular sciences.
[28] J. Rungby,et al. Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases , 2020, International journal of molecular sciences.
[29] L. Zhuang,et al. Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy , 2020, Protein & Cell.
[30] T. Raife,et al. β-Hydroxybutyrate inhibits inflammasome activation to attenuate Alzheimer’s disease pathology , 2020, Journal of neuroinflammation.
[31] Erqun Song,et al. Fostered Nrf2 expression antagonizes iron overload and glutathione depletion to promote resistance of neuron-like cells to ferroptosis. , 2020, Toxicology and applied pharmacology.
[32] P. So,et al. Iron dyshomeostasis, lipid peroxidation and perturbed expression of cystine/glutamate antiporter in Alzheimer’s disease: Evidence of ferroptosis , 2020, Redox biology.
[33] B. de Strooper,et al. The β-Secretase BACE1 in Alzheimer’s Disease , 2020, Biological Psychiatry.
[34] Junjian Zhang,et al. Iron Metabolism, Ferroptosis, and the Links With Alzheimer’s Disease , 2020, Frontiers in Neuroscience.
[35] Hugo Geerts,et al. Challenges in Alzheimer's Disease Drug Discovery and Development: The Role of Modeling, Simulation, and Open Data , 2020, Clinical pharmacology and therapeutics.
[36] Can Liu,et al. Mitochondria regulation in ferroptosis. , 2019, European journal of cell biology.
[37] B. Stockwell,et al. The development of the concept of ferroptosis. , 2019, Free radical biology & medicine.
[38] H. Kawabata. Transferrin and transferrin receptors update , 2019, Free radical biology & medicine.
[39] J. Schneider,et al. Brain iron is associated with accelerated cognitive decline in people with Alzheimer pathology , 2019, Molecular Psychiatry.
[40] Haiying Li,et al. Glutathione peroxidase 4 participates in secondary brain injury through mediating ferroptosis in a rat model of intracerebral hemorrhage , 2018, Brain Research.
[41] M. Carrara,et al. Dexamethasone counteracts hepatic inflammation and oxidative stress in cholestatic rats via CAR activation , 2018, PloS one.
[42] Mou-wang Zhou,et al. Ketogenic diet attenuates oxidative stress and inflammation after spinal cord injury by activating Nrf2 and suppressing the NF-κB signaling pathways , 2018, Neuroscience Letters.
[43] Scott Ayton,et al. Iron and Alzheimer's Disease: An Update on Emerging Mechanisms. , 2018, Journal of Alzheimer's disease : JAD.
[44] Aikseng Ooi,et al. The Roles of NRF2 in Modulating Cellular Iron Homeostasis , 2017, Antioxidants & redox signaling.
[45] W. Frey,et al. Intranasal deferoxamine affects memory loss, oxidation, and the insulin pathway in the streptozotocin rat model of Alzheimer's disease , 2017, Journal of the Neurological Sciences.
[46] Qitao Ran,et al. Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration , 2017, Redox biology.
[47] G. Rose,et al. Glucose tolerance and insulin sensitivity are impaired in APP/PS1 transgenic mice prior to amyloid plaque pathogenesis and cognitive decline , 2017, Experimental Gerontology.
[48] Aritri Bir,et al. The Oral Iron Chelator, Deferasirox, Reverses the Age-Dependent Alterations in Iron and Amyloid-β Homeostasis in Rat Brain: Implications in the Therapy of Alzheimer's Disease. , 2015, Journal of Alzheimer's disease : JAD.
[49] F. Liu,et al. The neuroprotective effects of β-hydroxybutyrate on Aβ-injected rat hippocampus in vivo and in Aβ-treated PC-12 cells in vitro , 2015, Free radical research.
[50] A. Bianco,et al. Effects of n-3 Polyunsaturated Fatty Acids (ω-3) Supplementation on Some Cardiovascular Risk Factors with a Ketogenic Mediterranean Diet , 2015, Marine drugs.
[51] Susan M Resnick,et al. Changes in Brain Function Occur Years before the Onset of Cognitive Impairment , 2013, The Journal of Neuroscience.
[52] D. Lane,et al. Mammalian iron homeostasis in health and disease: uptake, storage, transport, and molecular mechanisms of action. , 2013, Antioxidants & redox signaling.
[53] M. Murphy,et al. A ketogenic diet improves motor performance but does not affect β-amyloid levels in a mouse model of Alzheimer's Disease , 2013, Brain Research.
[54] R. Nelson,et al. Hyperlipidemia as a risk factor for cardiovascular disease. , 2013, Primary care.
[55] Pu Wang,et al. Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain , 2013, Neurochemistry International.
[56] M. R. Lamprecht,et al. Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death , 2012, Cell.
[57] Manisha N. Patel,et al. Acute oxidative stress and systemic Nrf2 activation by the ketogenic diet , 2010, Neurobiology of Disease.
[58] M. Schrag,et al. Deferiprone reduces amyloid-β and tau phosphorylation levels but not reactive oxygen species generation in hippocampus of rabbits fed a cholesterol-enriched diet. , 2012, Journal of Alzheimer's disease : JAD.
[59] P. Maher,et al. Regulation of xCT expression and system $$ x_{\text{c}}^{ - } $$ function in neuronal cells , 2011, Amino Acids.