Combined excitotoxic–oxidative stress and the concept of non-cell autonomous pathology of ALS: Insights into motoneuron axonopathy and astrogliosis
暂无分享,去创建一个
Philip M. Beart | R. D. O'Shea | P. Beart | Chrissandra J. Zagami | Nicole Wallis | Ross D. O’Shea | Nicole Wallis | R. D. O’Shea
[1] S. K. Malhotra,et al. Reactive astrocytes: cellular and molecular cues to biological function , 1997, Trends in Neurosciences.
[2] P. Beart,et al. Cyclothiazide and GYKI 52466 modulate AMPA receptor-mediated apoptosis in cortical neuronal cultures , 1999, Neuroscience Letters.
[3] P. Shaw,et al. Science, medicine, and the future: Motor neurone disease , 1999 .
[4] P. Bär. Motor neuron disease in vitro: the use of cultured motor neurons to study amyotrophic lateral sclerosis. , 2000, European journal of pharmacology.
[5] W. Robberecht,et al. Ca2+-permeable AMPA receptors and selective vulnerability of motor neurons , 2000, Journal of the Neurological Sciences.
[6] G.,et al. Annexin V for Flow Cytometric Detection of Phosphatidylserine Expression on B Cells Undergoing Apoptosis , 2000 .
[7] K. Talbot,et al. Motor neurone disease , 2002, Postgraduate medical journal.
[8] J. Weiss,et al. Disruption of Glial Glutamate Transport by Reactive Oxygen Species Produced in Motor Neurons , 2003, The Journal of Neuroscience.
[9] E. Hughes,et al. Loss of glial fibrillary acidic protein results in decreased glutamate transport and inhibition of PKA-induced EAAT2 cell surface trafficking. , 2004, Brain research. Molecular brain research.
[10] L. Barbeito,et al. A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis , 2004, Brain Research Reviews.
[11] R. D. O'Shea,et al. Binding and transport of [3H](2S,4R)‐ 4‐methylglutamate, a new ligand for glutamate transporters, demonstrate labeling of EAAT1 in cultured murine astrocytes , 2004, Journal of neuroscience research.
[12] Mark Ellisman,et al. Absence of Glial Fibrillary Acidic Protein and Vimentin Prevents Hypertrophy of Astrocytic Processes and Improves Post-Traumatic Regeneration , 2004, The Journal of Neuroscience.
[13] Jianzheng Zhou,et al. Glutamate Transporter Cluster Formation in Astrocytic Processes Regulates Glutamate Uptake Activity , 2004, The Journal of Neuroscience.
[14] M. Nilsson,et al. Astrocyte activation and reactive gliosis , 2005, Glia.
[15] G. McCormack,et al. Glutamate induces rapid loss of axonal neurofilament proteins from cortical neurons in vitro , 2005, Experimental Neurology.
[16] G. Bonvento,et al. Neuron–astrocyte interactions in the regulation of brain energy metabolism: a focus on NMR spectroscopy , 2006, Journal of neurochemistry.
[17] W. Robberecht,et al. The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis. , 2006, Biochimica et biophysica acta.
[18] D. Pow,et al. Effects of lipopolysaccharide on glial phenotype and activity of glutamate transporters: Evidence for delayed up-regulation and redistribution of GLT-1 , 2006, Neurochemistry International.
[19] J. Rothstein,et al. Mechanisms of Disease: astrocytes in neurodegenerative disease , 2006, Nature Clinical Practice Neurology.
[20] G. Kollias,et al. Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia , 2006, Science.
[21] L. Chimelli,et al. Expression of ubiquitin and proteasome in motorneurons and astrocytes of spinal cords from patients with amyotrophic lateral sclerosis , 2006, Neuroscience Letters.
[22] M. Haber,et al. Reshaping neuron-glial communication at hippocampal synapses. , 2005, Neuron glia biology.
[23] Hynek Wichterle,et al. Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons , 2007, Nature Neuroscience.
[24] Kevin Eggan,et al. Non–cell autonomous effect of glia on motor neurons in an embryonic stem cell–based ALS model , 2007, Nature Neuroscience.
[25] R. D. O'Shea,et al. Transporters for L‐glutamate: An update on their molecular pharmacology and pathological involvement , 2007, British journal of pharmacology.
[26] J. Vickers,et al. Excitotoxicity mediated by non‐NMDA receptors causes distal axonopathy in long‐term cultured spinal motor neurons , 2007, The European journal of neuroscience.
[27] T. Raju,et al. Altered in-vitro and in-vivo expression of glial glutamate transporter-1 following exposure to cerebrospinal fluid of amyotrophic lateral sclerosis patients , 2007, Journal of the Neurological Sciences.
[28] M. Robinson,et al. The role of glutamate transporters in neurodegenerative diseases and potential opportunities for intervention , 2007, Neurochemistry International.
[29] J. Morris,et al. TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions. , 2007, The American journal of pathology.
[30] J. Silver,et al. CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure , 2008, Experimental Neurology.
[31] P. Carmeliet,et al. Protective Role of Reactive Astrocytes in Brain Ischemia , 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[32] K. Talbot,et al. Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS , 2008, Progress in Neurobiology.
[33] P. Beart,et al. Oxidative and excitotoxic insults exert differential effects on spinal motoneurons and astrocytic glutamate transporters: Implications for the role of astrogliosis in amyotrophic lateral sclerosis , 2009, Glia.
[34] M. Sofroniew,et al. Astrocytes: biology and pathology , 2009, Acta Neuropathologica.
[35] A. Rigalli,et al. Experimental Models for the Study of Diabetes , 2009 .
[36] R. Tapia,et al. Molecular Neurodegeneration BioMed Central Review , 2009 .
[37] C. L. Lau,et al. GABAergic striatal neurons exhibit caspase‐independent, mitochondrially mediated programmed cell death , 2009, Journal of neurochemistry.
[38] Philip M. Beart,et al. Regulation of glutamate transporters in astrocytes: Evidence for a relationship between transporter expression and astrocytic phenotype , 2009, Neurotoxicity Research.
[39] P. Shaw,et al. Molecular factors underlying selective vulnerability of motor neurons to neurodegeneration in amyotrophic lateral sclerosis , 2009, Journal of Neurology.
[40] D. Cleveland,et al. Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond , 2009, The Journal of cell biology.
[41] Y. Matsui,et al. A semiquantitative analysis of reactive astrogliosis demonstrates its correlation with the number of intact motor neurons after transient spinal cord ischemia. , 2009, The Journal of thoracic and cardiovascular surgery.
[42] Don W. Cleveland,et al. Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond , 2009 .
[43] Anthony Brown,et al. A hereditary spastic paraplegia mutation in kinesin-1A/KIF5A disrupts neurofilament transport , 2010, Molecular Neurodegeneration.
[44] P. Beart,et al. Multifaceted deaths orchestrated by mitochondria in neurones. , 2010, Biochimica et biophysica acta.
[45] A. Acevedo-Arozena,et al. SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments , 2011, Mammalian Genome.
[46] I. Ferrer,et al. Cell stress induces TDP-43 pathological changes associated with ERK1/2 dysfunction: implications in ALS , 2011, Acta Neuropathologica.
[47] A. Ratti,et al. Dysregulation of axonal transport and motorneuron diseases , 2011, Biology of the cell.
[48] J. Vickers,et al. Neuron–glia interactions underlie ALS-like axonal cytoskeletal pathology , 2011, Neurobiology of Aging.
[49] V. Perreau,et al. Transcriptomic profiling of astrocytes treated with the Rho kinase inhibitor Fasudil reveals cytoskeletal and pro‐survival responses , 2012, Journal of cellular physiology.
[50] R. Pedersen,et al. Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms , 2011, Cell Death and Differentiation.