Comprehensive Genomic Analysis of a BRCA2 Deficient Human Pancreatic Cancer
暂无分享,去创建一个
A. Ashworth | M. Zvelebil | I. Kozarewa | K. Fenwick | I. Assiotis | Jarle Hakas | C. Lord | D. Sims | C. Mitsopoulos | L. Barber | J. M. Rosa Rosa
[1] N. Carter,et al. Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development , 2011, Cell.
[2] M. Nowak,et al. Distant Metastasis Occurs Late during the Genetic Evolution of Pancreatic Cancer , 2010, Nature.
[3] Jana Marie Schwarz,et al. MutationTaster evaluates disease-causing potential of sequence alterations , 2010, Nature Methods.
[4] A. Ashworth,et al. An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers , 2010, Breast Cancer Research and Treatment.
[5] T. Sasaki,et al. Identification of Zfp521/ZNF521 as a cooperative gene for E2A-HLF to develop acute B-lineage leukemia , 2010, Oncogene.
[6] Joshua F. McMichael,et al. Genome Remodeling in a Basal-like Breast Cancer Metastasis and Xenograft , 2010, Nature.
[7] E. Birney,et al. A small cell lung cancer genome reports complex tobacco exposure signatures , 2009, Nature.
[8] Tom Royce,et al. A comprehensive catalogue of somatic mutations from a human cancer genome , 2010, Nature.
[9] Barry Merriman,et al. U87MG Decoded: The Genomic Sequence of a Cytogenetically Aberrant Human Cancer Cell Line , 2010, PLoS genetics.
[10] A. Boyd,et al. The role of Eph receptors and ephrin ligands in colorectal cancer , 2009, International journal of cancer.
[11] A. Børresen-Dale,et al. COMPLEX LANDSCAPES OF SOMATIC REARRANGEMENT IN HUMAN BREAST CANCER GENOMES , 2009, Nature.
[12] R. Wilson,et al. BreakDancer: An algorithm for high resolution mapping of genomic structural variation , 2009, Nature Methods.
[13] N. Lemoine,et al. Pancreatic cancer: molecular pathogenesis and new therapeutic targets , 2009, Nature Reviews Gastroenterology &Hepatology.
[14] Kai Ye,et al. Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads , 2009, Bioinform..
[15] Gonçalo R. Abecasis,et al. The Sequence Alignment/Map format and SAMtools , 2009, Bioinform..
[16] Sangsoo Kim,et al. The first Korean genome sequence and analysis: full genome sequencing for a socio-ethnic group. , 2009, Genome research.
[17] Richard Durbin,et al. Sequence analysis Fast and accurate short read alignment with Burrows – Wheeler transform , 2009 .
[18] Z. Ning,et al. Amplification-free Illumina sequencing-library preparation facilitates improved mapping and assembly of GC-biased genomes , 2009, Nature Methods.
[19] A. Ashworth,et al. A high-resolution integrated analysis of genetic and expression profiles of breast cancer cell lines , 2009, Breast Cancer Research and Treatment.
[20] David A. Gadish. Promoting Online Sales of Dental Supplies on a Tight Budget , 2008 .
[21] G. Parmigiani,et al. Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses , 2008, Science.
[22] A. Ashworth,et al. Targeted therapy for cancer using PARP inhibitors. , 2008, Current opinion in pharmacology.
[23] Antony V. Cox,et al. Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing , 2008, Nature Genetics.
[24] A. Jemal,et al. Cancer Statistics, 2008 , 2008, CA: a cancer journal for clinicians.
[25] Jorge S. Reis-Filho,et al. Resistance to therapy caused by intragenic deletion in BRCA2 , 2008, Nature.
[26] Giovanni Parmigiani,et al. Breast cancer risk among male BRCA1 and BRCA2 mutation carriers. , 2007, Journal of the National Cancer Institute.
[27] A. Sparks,et al. The Genomic Landscapes of Human Breast and Colorectal Cancers , 2007, Science.
[28] L. Pellegrini,et al. Corrigendum: Interaction with the BRCA2 C terminus protects RAD51|[ndash]|DNA filaments from disassembly by BRC repeats , 2007 .
[29] Luca Pellegrini,et al. Interaction with the BRCA2 C terminus protects RAD51–DNA filaments from disassembly by BRC repeats , 2007, Nature Structural &Molecular Biology.
[30] Edward H Egelman,et al. Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2 , 2007, Nature Structural &Molecular Biology.
[31] Jin Namkoong,et al. Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma. , 2007, Cancer research.
[32] G. Parmigiani,et al. The Consensus Coding Sequences of Human Breast and Colorectal Cancers , 2006, Science.
[33] A. Ashworth,et al. The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability , 2006, Oncogene.
[34] M. Satake,et al. SMAP2, a novel ARF GTPase-activating protein, interacts with clathrin and clathrin assembly protein and functions on the AP-1-positive early endosome/trans-Golgi network. , 2006, Molecular biology of the cell.
[35] A. Bell,et al. Aberrant Wnt/β-Catenin Signaling in Pancreatic Adenocarcinoma , 2006 .
[36] D. Weinstock,et al. A model of oncogenic rearrangements: differences between chromosomal translocation mechanisms and simple double-strand break repair. , 2006, Blood.
[37] C. Turnbull,et al. Genetic predisposition to cancer. , 2005, Clinical medicine.
[38] Eric I. Danek,et al. Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance , 2004, The Journal of cell biology.
[39] T. Hubbard,et al. A census of human cancer genes , 2004, Nature Reviews Cancer.
[40] Steven Henikoff,et al. SIFT: predicting amino acid changes that affect protein function , 2003, Nucleic Acids Res..
[41] J. Hopper,et al. Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies. , 2003, American journal of human genetics.
[42] Wen-Hwa Lee,et al. BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure. , 2002, Science.
[43] M. Katoh,et al. Frizzled-10, up-regulated in primary colorectal cancer, is a positive regulator of the WNT - beta-catenin - TCF signaling pathway. , 2002, International journal of molecular medicine.
[44] A. Ashworth,et al. Mutation in Brca2 stimulates error‐prone homology‐directed repair of DNA double‐strand breaks occurring between repeated sequences , 2001, The EMBO journal.
[45] J. Nathans,et al. Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains , 2001, Nature.
[46] J. Hoeijmakers. Genome maintenance mechanisms for preventing cancer , 2001, Nature.
[47] M. Jasin,et al. BRCA2 is required for homology-directed repair of chromosomal breaks. , 2001, Molecular cell.
[48] S. Kern,et al. Homozygous deletions inactivate DCC, but not MADH4/DPC4/SMAD4, in a subset of pancreatic and biliary cancers , 2000, Genes, chromosomes & cancer.
[49] F. Gage,et al. Truncated BRCA2 is cytoplasmic: implications for cancer-linked mutations. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[50] B. Koller,et al. Brca1 controls homology-directed DNA repair. , 1999, Molecular cell.
[51] M. Hirai,et al. Molecular cloning of Frizzled-10, a novel member of the Frizzled gene family. , 1999, Biochemical and biophysical research communications.
[52] G E Tomlinson,et al. BRCA2 is required for ionizing radiation-induced assembly of Rad51 complex in vivo. , 1999, Cancer research.
[53] A. Schudy,et al. Higher frequency of DPC4/Smad4 alterations in pancreatic cancer cell lines than in primary pancreatic adenocarcinomas. , 1999, Cancer letters.
[54] P. Meltzer,et al. Specific chromosomal aberrations and amplification of the AIB1 nuclear receptor coactivator gene in pancreatic carcinomas. , 1999, The American journal of pathology.
[55] P. Bucher,et al. The frizzled motif: in how many different protein families does it occur? , 1998, Trends in biochemical sciences.
[56] Shahrooz Rabizadeh,et al. The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis , 1998, Nature.
[57] M. Skolnick,et al. Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor. , 1997, Cancer research.
[58] H. Friess,et al. Absence of K-ras mutations in the pancreatic parenchyma of patients with chronic pancreatitis. , 1997, American journal of surgery.
[59] C. Moskaluk,et al. Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas. , 1996, Cancer research.
[60] M. Masu,et al. Deleted in Colorectal Cancer (DCC) Encodes a Netrin Receptor , 1996, Cell.
[61] T. Savarese,et al. Gene deletion chemoselectivity: codeletion of the genes for p16(INK4), methylthioadenosine phosphorylase, and the alpha- and beta-interferons in human pancreatic cell carcinoma lines and its implications for chemotherapy. , 1996, Cancer research.
[62] T. Lindahl. Instability and decay of the primary structure of DNA , 1993, Nature.
[63] G. Lauer,et al. p53 and K-RAS alterations in pancreatic epithelial cell lesions. , 1993, Oncogene.
[64] T. Orfeo,et al. One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice. , 1977, Journal of the National Cancer Institute.
[65] J. Fogh,et al. Absence of HeLa cell contamination in 169 cell lines derived from human tumors. , 1977, Journal of the National Cancer Institute.
[66] Brad T. Sherman,et al. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.
[67] A. Bell,et al. Aberrant Wnt/beta-catenin signaling in pancreatic adenocarcinoma. , 2006, Neoplasia.
[68] N. Dubrawsky. Cancer statistics , 1989, CA: a cancer journal for clinicians.