Hepatic artery reconstruction in living donor liver transplantation using surgical loupes: Achieving low rate of hepatic arterial thrombosis in 741 consecutive recipients—tips and tricks to overcome the poor hepatic arterial flow

The reconstruction of the hepatic artery (HA) is the most complex step in living donor liver transplantation (LDLT) because of the smaller diameter of the artery and the increased risk of HA‐related complications. Because of the smaller diameter of the HA, many centers use a microsurgical technique with interrupted sutures for arterial anastomosis. The aim of our study was to retrospectively investigate the outcomes after HA reconstruction performed under magnifying loupes using the “parachute technique.” From August 1, 2002 to August 31, 2016, LDLT was performed in 766 recipients. HA reconstruction for the initial 25 LDLT surgeries was performed using a microsurgery technique (era 1). From May 2007 until the end date, HA reconstruction was performed in 741 recipients by a “parachute technique” under surgical loupes (era 2). HA reconstruction was performed using surgical loupes in 737 adults (male:female, 526:211) and 4 pediatric patients (male:female, 3:1). The average diameter of the donor graft HA was 2.8 mm (range, 1‐6.5 mm). The most notable factor in this era was the quick HA anastomosis procedure with a mean time of 10 ± 5 minutes (range, 5‐30 minutes). In era 2, 9 (1.21%) patients developed hepatic artery thrombosis (HAT), whereas 2 patients developed nonthrombotic HA‐related complications. Extra‐anatomic HA reconstruction was performed in 14 patients due to either primary HA anastomosis failure or a poor caliber recipient HA. The use of magnifying surgical loupes to perform HA reconstruction is safe, feasible, and yields a low incidence of HA‐related complications. The “parachute technique” for HA reconstruction can achieve a speedy reconstruction without increasing the risk of HAT. Liver Transplantation 23 887–898 2017 AASLD.

[1]  Horng-ren Yang,et al.  Successful application of supraceliac aortohepatic conduit using saphenous venous graft in right Lobe living donor liver transplantation , 2017, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[2]  Wei-Chen Lee,et al.  Endovascular treatment for pseudoaneurysms arising from the hepatic artery after liver transplantation. , 2017, Asian journal of surgery.

[3]  E. Gad,et al.  Hepatic arterial and portal venous complications after adult and pediatric living donor liver transplantation, risk factors, management and outcome (A retrospective cohort study)☆ , 2016, Annals of medicine and surgery.

[4]  Horng-ren Yang,et al.  “Rooftop and Skeletonization Technique” of Hepatic Transection to Include or Exclude the Middle Hepatic Vein During Donor Hepatectomy in Living Donor Liver Transplantation: Solving the Middle Hepatic Vein Controversy – Experience in 397 Sequential Live Donors , 2016 .

[5]  Horng-ren Yang,et al.  "V-Plasty" technique using dual synthetic vascular grafts to reconstruct outflow channel in living donor liver transplantation. , 2015, Surgery.

[6]  J. Belghiti,et al.  The recipient celiac trunk as an alternative to the native hepatic artery for arterial reconstruction in adult liver transplantation , 2015, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[7]  U. Tannuri,et al.  A new simplified technique of arterial reconstruction in pediatric living-donor liver transplantation: a comparison with the classical technique. , 2014, Journal of pediatric surgery.

[8]  H. Eguchi,et al.  Hepatic Artery Reconstruction in Living Donor Liver Transplantation: Risk Factor Analysis of Complication and a Role of MDCT Scan for Detecting Anastomotic Stricture , 2013, World Journal of Surgery.

[9]  Horng-ren Yang,et al.  Hepatic artery reconstruction in living donor liver transplantation: running suture under surgical loupes by cardiovascular surgeons in 180 recipients. , 2012, Transplantation proceedings.

[10]  C. Hsieh,et al.  Continuous versus interrupted suture for hepatic artery reconstruction using a loupe in living-donor liver transplantation. , 2011, Annals of transplantation.

[11]  H. Ohdan,et al.  Long-term outcome of hepatic artery reconstruction during living-donor liver transplantation. , 2011, Transplantation proceedings.

[12]  H. Karakayalı,et al.  Management of early hepatic arterial thrombosis after pediatric living-donor liver transplantation. , 2011, Transplantation proceedings.

[13]  M. Enne,et al.  Hepatic artery reconstruction in pediatric living donor liver transplantation under 10 kg, without microscope use , 2010, Pediatric transplantation.

[14]  C. Viana,et al.  Continuous versus interrupted suture for hepatic artery anastomosis in liver transplantation: differences in the incidence of hepatic artery thrombosis. , 2008, Transplantation proceedings.

[15]  J. Won,et al.  Endovascular treatment of acute arterial complications after living-donor liver transplantation. , 2008, Clinical radiology.

[16]  L. Jeng,et al.  Innovative technique to reconstruct two branches of the right hepatic artery in living donor liver transplantation. , 2008, Transplantation proceedings.

[17]  R. Montgomery,et al.  HEPATIC ARTERY THROMBOSIS AFTER PEDIATRIC LIVER TRANSPLANTATION: IDENTIFICATION AND CHARACTERIZATION OF A NOVEL RISK FACTOR: 577 , 2008 .

[18]  T. Asahara,et al.  Microsurgical hepatic artery reconstruction during living‐donor liver transplantation by using head‐mounted surgical binocular system , 2007, Transplant international : official journal of the European Society for Organ Transplantation.

[19]  I. Oran,et al.  Vascular complications after liver transplantation: evaluation with Doppler US , 2007, Abdominal Imaging.

[20]  S. Fan,et al.  Treatment of hepatic artery thrombosis after orthotopic liver transplantation. , 2004, Asian journal of surgery.

[21]  T. Kim,et al.  Vascular complications after living related liver transplantation: evaluation with gadolinium-enhanced three-dimensional MR angiography. , 2003, AJR. American journal of roentgenology.

[22]  P. Sinha,et al.  Microvascular hepatic artery anastomosis in pediatric segmental liver transplantation: microscope vs loupe , 2002, Transplant international : official journal of the European Society for Organ Transplantation.

[23]  S. Kawasaki,et al.  An alternative method of arterial reconstruction after hepatic arterial thrombosis following living-related liver transplantation. , 2000, Transplantation.

[24]  Y. Yamaoka,et al.  Liver transplantation in children from living-related donors. , 1993, Transplantation proceedings.

[25]  Y. Yamaoka,et al.  THE INTRODUCTION OF MICROVASCULAR SURGERY TO HEPATIC ARTERY RECONSTRUCTION IN LIVING‐DONOR LIVER TRANSPLANTATION—ITS SURGICAL ADVANTAGES COMPARED WITH CONVENTIONAL PROCEDURES , 1992, Transplantation.

[26]  J. Emond,et al.  Liver transplantation in children from living related donors. Surgical techniques and results. , 1991, Annals of surgery.

[27]  V. Mazzaferro,et al.  Hepatic artery thrombosis after pediatric liver transplantation--a medical or surgical event? , 1989, Transplantation.

[28]  Y. Yasuda,et al.  A comparison of open surgery and endovascular intervention for hepatic artery complications after pediatric liver transplantation. , 2013, Transplantation proceedings.

[29]  N. Harada,et al.  Hepatic artery reconstruction in living-donor liver transplantation: a review of its techniques and complications. , 2002, Surgery.

[30]  T. Inomoto,et al.  Experiences of 120 microsurgical reconstructions of hepatic artery in living related liver transplantation. , 1996, Surgery.

[31]  Hong-Jin Kim,et al.  Surgical techniques and innovations in living related liver transplantation. , 1993, Annals of surgery.