Commensal gut bacteria: mechanisms of immune modulation.

[1]  M. Chamaillard,et al.  NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. , 2005, Annual review of biochemistry.

[2]  Benjamin P. Westover,et al.  Glycan Foraging in Vivo by an Intestine-Adapted Bacterial Symbiont , 2005, Science.

[3]  L. Comstock,et al.  Human Symbionts Use a Host-Like Pathway for Surface Fucosylation , 2005, Science.

[4]  G. Rook,et al.  Microbes, immunoregulation, and the gut , 2005, Gut.

[5]  Richard A. Flavell,et al.  Nod2-Dependent Regulation of Innate and Adaptive Immunity in the Intestinal Tract , 2005, Science.

[6]  D. Merlin,et al.  Salmonella typhimurium transcytoses flagellin via an SPI2-mediated vesicular transport pathway , 2004, Journal of Cell Science.

[7]  Ting Wang,et al.  The gut microbiota as an environmental factor that regulates fat storage. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[8]  R. Sartor,et al.  Interleukin 10-Deficient Mice Exhibit Defective Colonic Muc2 Synthesis Before and After Induction of Colitis by Commensal Bacteria , 2004, Inflammatory bowel diseases.

[9]  M. Rescigno,et al.  Mucosal dendritic cells in immunity and inflammation , 2004, Nature Immunology.

[10]  M. Netea,et al.  Toll-like receptors as an escape mechanism from the host defense. , 2004, Trends in microbiology.

[11]  P. Brigidi,et al.  Modulation of human dendritic cell phenotype and function by probiotic bacteria , 2004, Gut.

[12]  F. Taddei,et al.  In Vitro and ex Vivo Activation of the TLR5 Signaling Pathway in Intestinal Epithelial Cells by a Commensal Escherichia coli Strain* , 2004, Journal of Biological Chemistry.

[13]  T. Macdonald,et al.  Smad7 in TGF-β-mediated negative regulation of gut inflammation , 2004 .

[14]  Matthew T Wheeler,et al.  The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses , 2004, Nature Immunology.

[15]  A. Iwasaki,et al.  Toll-like receptor control of the adaptive immune responses , 2004, Nature Immunology.

[16]  M. Kokkinidis,et al.  Conserved features of type III secretion , 2004, Cellular microbiology.

[17]  E. Zoetendal,et al.  Molecular microbial ecology of the gastrointestinal tract: from phylogeny to function. , 2004, Current issues in intestinal microbiology.

[18]  D. Haller,et al.  15-Deoxy-Δ12,14-prostaglandin J2-mediated ERK Signaling Inhibits Gram-negative Bacteria-induced RelA Phosphorylation and Interleukin-6 Gene Expression in Intestinal Epithelial Cells through Modulation of Protein Phosphatase 2A Activity* , 2004, Journal of Biological Chemistry.

[19]  M. Fukuda,et al.  Natural Antibiotic Function of a Human Gastric Mucin Against Helicobacter pylori Infection , 2004, Science.

[20]  E. Remaut,et al.  Active delivery of trefoil factors by genetically modified Lactococcus lactis prevents and heals acute colitis in mice. , 2004, Gastroenterology.

[21]  M. Hornef,et al.  Increased diversity of intestinal antimicrobial peptides by covalent dimer formation , 2004, Nature Immunology.

[22]  J. Flynn.  Mutual attraction: Does it benefit the host or the bug? , 2004, Nature Immunology.

[23]  Tomohiro Watanabe,et al.  NOD2 is a negative regulator of Toll-like receptor 2–mediated T helper type 1 responses , 2004, Nature Immunology.

[24]  Ruslan Medzhitov,et al.  Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis , 2004, Cell.

[25]  A. Saxon.  Faculty Opinions recommendation of Toll-like receptor 4 signaling by intestinal microbes influences susceptibility to food allergy. , 2004 .

[26]  L. A. Ward,et al.  FlaC, a protein of Campylobacter jejuni TGH9011 (ATCC43431) secreted through the flagellar apparatus, binds epithelial cells and influences cell invasion , 2004, Molecular microbiology.

[27]  G. Gerken,et al.  Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C. , 2004, Gastroenterology.

[28]  Jun Sun,et al.  Bacterial activation of β-catenin signaling in human epithelia , 2004 .

[29]  A. Macpherson,et al.  Interactions between commensal intestinal bacteria and the immune system , 2004, Nature Reviews Immunology.

[30]  R Balfour Sartor,et al.  Therapeutic manipulation of the enteric microflora in inflammatory bowel diseases: antibiotics, probiotics, and prebiotics. , 2004, Gastroenterology.

[31]  F. Liew,et al.  ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance , 2004, Nature Immunology.

[32]  G. Bergonzelli,et al.  Cell Surface-Associated Elongation Factor Tu Mediates the Attachment of Lactobacillus johnsonii NCC533 (La1) to Human Intestinal Cells and Mucins , 2004, Infection and Immunity.

[33]  Rodolphe Barrangou,et al.  The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[34]  A. Zuercher,et al.  Interactions of commensal gut microbes with subsets of B- and T-cells in the murine host. , 2004, Vaccine.

[35]  Keiichiro Suzuki,et al.  Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[36]  S. Akira,et al.  Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis. , 2004, Gastroenterology.

[37]  M. Kamm,et al.  Quantitative and functional characteristics of intestinal‐homing memory T cells: analysis of Crohn's disease patients and healthy controls , 2004, Clinical and experimental immunology.

[38]  Andrew S Neish,et al.  Bacterial inhibition of eukaryotic pro-inflammatory pathways , 2004, Immunologic research.

[39]  S. Pettersson,et al.  Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-γ and RelA , 2004, Nature Immunology.

[40]  S. Targan,et al.  Bacterial flagellin is a dominant antigen in Crohn disease. , 2004, The Journal of clinical investigation.

[41]  S. Hammarström,et al.  Carcinoembryonic antigen (CEA) and CEA-related cell adhesion molecule 1 (CEACAM1), apically expressed on human colonic M cells, are potential receptors for microbial adhesion , 2004, Histochemistry and Cell Biology.

[42]  C. Josenhans,et al.  Helicobacter pylori flagellins have very low intrinsic activity to stimulate human gastric epithelial cells via TLR5. , 2003, Microbes and infection.

[43]  A. Thomson,et al.  Dendritic cells: regulators of alloimmunity and opportunities for tolerance induction , 2003, Immunological reviews.

[44]  Richard J. Laws,et al.  A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease , 2003, The Journal of experimental medicine.

[45]  M. Lazar,et al.  Bacterial colonization leads to the colonic secretion of RELMbeta/FIZZ2, a novel goblet cell-specific protein. , 2003, Gastroenterology.

[46]  M. Hornef,et al.  Intracellular Recognition of Lipopolysaccharide by Toll-like Receptor 4 in Intestinal Epithelial Cells , 2003, The Journal of experimental medicine.

[47]  J. Madara,et al.  Flagellin Is the Major Proinflammatory Determinant of Enteropathogenic Salmonella1 , 2003, The Journal of Immunology.

[48]  M. Neurath,et al.  Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells. , 2003, The Journal of clinical investigation.

[49]  G. Stark,et al.  SIGIRR, a negative regulator of Toll-like receptor–interleukin 1 receptor signaling , 2003, Nature Immunology.

[50]  Shu-sen Lin,et al.  Human secretory immunoglobulin A may contribute to biofilm formation in the gut , 2003, Immunology.

[51]  F. Powrie,et al.  Colitogenic Th1 Cells Are Present in the Antigen-Experienced T Cell Pool in Normal Mice: Control by CD4+ Regulatory T Cells and IL-101 , 2003, The Journal of Immunology.

[52]  Vanessa Sperandio,et al.  Bacteria–host communication: The language of hormones , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[53]  Samuel I. Miller,et al.  A Salmonella enterica Serovar Typhimurium Translocated Leucine-Rich Repeat Effector Protein Inhibits NF-κB-Dependent Gene Expression , 2003, Infection and Immunity.

[54]  S. Targan,et al.  CC Chemokine Receptor 9 Expression Defines a Subset of Peripheral Blood Lymphocytes with Mucosal T Cell Phenotype and Th1 or T-Regulatory 1 Cytokine Profile 1 , 2003, The Journal of Immunology.

[55]  R. Schwabe,et al.  Transforming Growth Factor- (cid:1) 1 Inhibits Non-pathogenic Gram-negative Bacteria-induced NF- (cid:2) B Recruitment to the Interleukin-6 Gene Promoter in Intestinal Epithelial Cells through Modulation of Histone Acetylation* , 2022 .

[56]  T. Blundell,et al.  A Novel Type of Deubiquitinating Enzyme* , 2003, Journal of Biological Chemistry.

[57]  H. Nagai,et al.  Show me the substrates: modulation of host cell function by type IV secretion systems , 2003, Cellular microbiology.

[58]  A. Zuercher,et al.  B1 Cells Contribute to Serum IgM, But Not to Intestinal IgA, Production in Gnotobiotic Ig Allotype Chimeric Mice1 , 2003, The Journal of Immunology.

[59]  S. Nakagawa,et al.  A novel PPAR gamma gene therapy to control inflammation associated with inflammatory bowel disease in a murine model. , 2003, Gastroenterology.

[60]  Maxwell H. Anderson,et al.  Mutation of luxS Affects Biofilm Formation in Streptococcus mutans , 2003, Infection and Immunity.

[61]  Lynn K. Carmichael,et al.  A Genomic View of the Human-Bacteroides thetaiotaomicron Symbiosis , 2003, Science.

[62]  Jeffrey I. Gordon,et al.  Angiogenins: a new class of microbicidal proteins involved in innate immunity , 2003, Nature Immunology.

[63]  K. Michelsen,et al.  Human Intestinal Epithelial Cells Are Broadly Unresponsive to Toll-Like Receptor 2-Dependent Bacterial Ligands: Implications for Host-Microbial Interactions in the Gut 1 , 2003, The Journal of Immunology.

[64]  Ruslan Medzhitov,et al.  Toll Pathway-Dependent Blockade of CD4+CD25+ T Cell-Mediated Suppression by Dendritic Cells , 2003, Science.

[65]  P. Brandtzaeg,et al.  Microbial Colonization Drives Lymphocyte Accumulation and Differentiation in the Follicle-Associated Epithelium of Peyer’s Patches1 , 2003, The Journal of Immunology.

[66]  Nigel J. Saunders,et al.  CD4+CD25+ TR Cells Suppress Innate Immune Pathology Through Cytokine-dependent Mechanisms , 2003, The Journal of experimental medicine.

[67]  G. T. te Meerman,et al.  IBD and genetics: new developments. , 2003, Scandinavian journal of gastroenterology. Supplement.

[68]  T. Steiner,et al.  Two Nonadjacent Regions in Enteroaggregative Escherichia coli Flagellin Are Required for Activation of Toll-like Receptor 5* , 2002, The Journal of Biological Chemistry.

[69]  Peer Bork,et al.  The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[70]  Jun Sun,et al.  Cutting Edge: Salmonella AvrA Effector Inhibits the Key Proinflammatory, Anti-Apoptotic NF-κB Pathway1 , 2002, The Journal of Immunology.

[71]  E. Zoetendal,et al.  Mucosa-Associated Bacteria in the Human Gastrointestinal Tract Are Uniformly Distributed along the Colon and Differ from the Community Recovered from Feces , 2002, Applied and Environmental Microbiology.

[72]  M. Abreu,et al.  TLR4 and MD-2 Expression Is Regulated by Immune-mediated Signals in Human Intestinal Epithelial Cells* , 2002, The Journal of Biological Chemistry.

[73]  Vanessa Sperandio,et al.  Quorum sensing Escherichia coli regulators B and C (QseBC): a novel two‐component regulatory system involved in the regulation of flagella and motility by quorum sensing in E. coli , 2002, Molecular microbiology.

[74]  S. Akira,et al.  [Induction of direct antimicrobial activity through mammalian toll-like receptors]. , 2001, Pneumologie.

[75]  T. Macdonald,et al.  IL-12 and Th1 immune responses in human Peyer's patches. , 2001, Trends in immunology.

[76]  S. Akira,et al.  The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5 , 2001, Nature.

[77]  S. Pettersson,et al.  Absence of Toll-Like Receptor 4 Explains Endotoxin Hyporesponsiveness in Human Intestinal Epithelium , 2001, Journal of pediatric gastroenterology and nutrition.

[78]  J. Gordon,et al.  Molecular analysis of commensal host-microbial relationships in the intestine. , 2001, Science.

[79]  C. Hagedorn,et al.  Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response. , 2001, The Journal of clinical investigation.

[80]  A. Young,et al.  Prokaryotic Regulation of Epithelial Responses by Inhibition of IκB-α Ubiquitination , 2000 .

[81]  W. Fiers,et al.  Treatment of murine colitis by Lactococcus lactis secreting interleukin-10. , 2000, Science.

[82]  William C. Parks,et al.  Secretion of microbicidal α-defensins by intestinal Paneth cells in response to bacteria , 2000, Nature Immunology.

[83]  Jeff F. Miller,et al.  Modulation of host immune responses, induction of apoptosis and inhibition of NF‐κB activation by the Bordetella type III secretion system , 2000, Molecular microbiology.

[84]  A. Imaoka,et al.  Differential Roles of Segmented Filamentous Bacteria and Clostridia in Development of the Intestinal Immune System , 1999, Infection and Immunity.

[85]  M. Neurath,et al.  T cell specificity and cross reactivity towards enterobacteria,Bacteroides,Bifidobacterium, and antigens from resident intestinal flora in humans , 1999, Gut.

[86]  M. Neurath,et al.  The yopJ locus is required for Yersinia‐mediated inhibition of NF‐κB activation and cytokine expression: YopJ contains a eukaryotic SH2‐like domain that is essential for its repressive activity , 1998, Molecular microbiology.

[87]  Hervé Groux,et al.  A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis , 1997, Nature.

[88]  K. Tanaka,et al.  The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. , 1997, Journal of immunology.