Smartphone-based tape sensors for multiplexed rapid urinalysis

Abstract Recent advances in biofluids monitoring have positioned urine as a non-invasive candidate for clinical diagnosis. In this paper, we employ adhesive tapes with indicator-functionalized microarrays for rapid urinalysis. Such tape-based sensor combines advantages of flexibility, adhesive and waterproof functionality in a platform, which is simply prepared by physical punching, fabrics filling and indicators modification. The simulated urine flow can be captured and penetrated in the tape-based microarrays for rapid detection of multiplexed markers such as glucose, nitrite, protein and phenylpyruvate with a smartphone-assisted colorimetric screening method. As a user-friendly point-of-care testing (POCT) approach, such tape-based sensor is ideally favorable for the early disease warning toward the patients of urinary incontinence and infants.

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