Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators
暂无分享,去创建一个
Charles N. Serhan | Thomas E. Van Dyke | C. Serhan | N. Chiang | T. E. Dyke | Nan Chiang | T. Dyke | Chia Nan
[1] A. Rossi,et al. The Resolution of Inflammation , 2008, Inflammopharmacology.
[2] Geoff Bellingan,et al. Hematopoietic prostaglandin D2 synthase controls the onset and resolution of acute inflammation through PGD2 and 15-deoxyΔ12–14 PGJ2 , 2007, Proceedings of the National Academy of Sciences.
[3] O. Haworth,et al. Resolving the problem of persistence in the switch from acute to chronic inflammation , 2007, Proceedings of the National Academy of Sciences.
[4] C. Andry,et al. Resolvin E1 Regulates Inflammation at the Cellular and Tissue Level and Restores Tissue Homeostasis In Vivo1 , 2007, The Journal of Immunology.
[5] C. Serhan,et al. Resolvin E1 promotes mucosal surface clearance of neutrophils: a new paradigm for inflammatory resolution , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[6] K. Gronert,et al. Interdependence of lipoxin A4 and heme‐oxygenase in counter‐regulating inflammation during corneal wound healing , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[7] Lois E. H. Smith,et al. Increased dietary intake of ω-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis , 2007, Nature Medicine.
[8] Charles N. Serhan,et al. Resolvin E1 and protectin D1 activate inflammation-resolution programmes , 2007, Nature.
[9] J. Uddin,et al. Resolvin D1 and Its Aspirin-triggered 17R Epimer , 2007, Journal of Biological Chemistry.
[10] Charles N. Serhan,et al. Resolvin E1 Selectively Interacts with Leukotriene B4 Receptor BLT1 and ChemR23 to Regulate Inflammation1 , 2007, The Journal of Immunology.
[11] C. Svensson,et al. Lipoxins and aspirin-triggered lipoxin inhibit inflammatory pain processing , 2007, The Journal of experimental medicine.
[12] E. Israel,et al. Protectin D1 Is Generated in Asthma and Dampens Airway Inflammation and Hyperresponsiveness1 , 2007, The Journal of Immunology.
[13] J. Wallace,et al. Resolution of in flammation: state of the art, definitions and terms , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[14] I. Fierro,et al. Aspirin-triggered lipoxin A4 blocks reactive oxygen species generation in endothelial cells: A novel antioxidative mechanism , 2006, Thrombosis and Haemostasis.
[15] S. Gay,et al. Mechanisms of Disease: leukotrienes and lipoxins in scleroderma lung disease—insights and potential therapeutic implications , 2007, Nature Clinical Practice Rheumatology.
[16] W. Schiemann,et al. Apoptotic Cells, through Transforming Growth Factor-β, Coordinately Induce Anti-inflammatory and Suppress Pro-inflammatory Eicosanoid and NO Synthesis in Murine Macrophages* , 2006, Journal of Biological Chemistry.
[17] V. Arroyo,et al. Docosahexaenoic acid (DHA) blunts liver injury by conversion to protective lipid mediators: protectin D1 and 17S‐hydroxy‐DHA , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[18] Katherine B Percarpio,et al. Resolvin E2: identification and anti-inflammatory actions: pivotal role of human 5-lipoxygenase in resolvin E series biosynthesis. , 2006, Chemistry & biology.
[19] J. Duffield,et al. Resolvin D Series and Protectin D1 Mitigate Acute Kidney Injury1 , 2006, The Journal of Immunology.
[20] C. Serhan,et al. Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression , 2006, Nature Immunology.
[21] A. Nakajima,et al. Leukotriene B4 and lipoxin A4 are regulatory signals for neural stem cell proliferation and differentiation , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[22] Christopher Haslett,et al. Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis , 2006, Nature Medicine.
[23] Takao Shimizu,et al. The Lipoxin Receptor ALX: Potent Ligand-Specific and Stereoselective Actions in Vivo , 2006, Pharmacological Reviews.
[24] Yu Lin,et al. Augmentation of Myocardial Production of 15-Epi-Lipoxin-A4 by Pioglitazone and Atorvastatin in the Rat , 2006, Circulation.
[25] Chengwei He,et al. Melanoma growth is reduced in fat-1 transgenic mice: Impact of omega-6/omega-3 essential fatty acids , 2006, Proceedings of the National Academy of Sciences.
[26] K. Weylandt,et al. Transgenic mice rich in endogenous omega-3 fatty acids are protected from colitis. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[27] C. Serhan,et al. Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes. , 2006, The Journal of Immunology.
[28] M. Mangino,et al. Lipoxin biosynthesis in inflammatory bowel disease. , 2006, Prostaglandins & other lipid mediators.
[29] B. Levy,et al. RvE1 protects from local inflammation and osteoclastmediated bone destruction in periodontitis , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[30] Yan Lu,et al. Anti-Inflammatory Actions of Neuroprotectin D1/Protectin D1 and Its Natural Stereoisomers: Assignments of Dihydroxy-Containing Docosatrienes1 , 2006, The Journal of Immunology.
[31] I. Fierro,et al. Aspirin-triggered Lipoxin A4 inhibition of VEGF-induced endothelial cell migration involves actin polymerization and focal adhesion assembly , 2006, Oncogene.
[32] L. Dong,et al. Lipoxin A4 inhibits connective tissue growth factor-induced production of chemokines in rat mesangial cells. , 2006, Kidney international.
[33] R J Flower,et al. Prostaglandins, bioassay and inflammation , 2006, British journal of pharmacology.
[34] Sheng-hua Wu,et al. Lipoxin A4 inhibits proliferation of human lung fibroblasts induced by connective tissue growth factor. , 2006, American journal of respiratory cell and molecular biology.
[35] C. Serhan,et al. The Docosatriene Protectin D1 Is Produced by TH2 Skewing and Promotes Human T Cell Apoptosis via Lipid Raft Clustering* , 2005, Journal of Biological Chemistry.
[36] R. Alon,et al. Immune cell migration in inflammation: present and future therapeutic targets , 2005, Nature Immunology.
[37] Charles N Serhan,et al. A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease. , 2005, The Journal of clinical investigation.
[38] L. Palmer,et al. Diminished lipoxin biosynthesis in severe asthma. , 2005, American journal of respiratory and critical care medicine.
[39] I. Fierro,et al. Novel lipid mediator aspirin-triggered lipoxin A4 induces heme oxygenase-1 in endothelial cells. , 2005, American journal of physiology. Cell physiology.
[40] Makoto Arita,et al. Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[41] Charles N. Serhan,et al. Molecular circuits of resolution: formation and actions of resolvins and protectins , 2005, The Journal of Immunology.
[42] N. Maheshwari,et al. A Role for the Mouse 12/15-Lipoxygenase Pathway in Promoting Epithelial Wound Healing and Host Defense* , 2005, Journal of Biological Chemistry.
[43] Yan Lu,et al. Mediator-lipidomics: databases and search algorithms for PUFA-derived mediators. , 2005, Journal of lipid research.
[44] A. Sher,et al. Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1 , 2005, The Journal of experimental medicine.
[45] M. Arnaout,et al. A synthetic eicosanoid LX‐mimetic unravels host‐donor interactions in allogeneic BMT‐induced GvHD to reveal an early protective role for host neutrophils , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[46] J. Parkinson,et al. A beta-oxidation-resistant lipoxin A4 analog treats hapten-induced colitis by attenuating inflammation and immune dysfunction. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[47] B. Rasmusson,et al. Differential inside-out activation of beta2-integrins by leukotriene B4 and fMLP in human neutrophils. , 2004, Experimental cell research.
[48] P. Ridker,et al. Aspirin triggers antiinflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[49] C. Serhan. A search for endogenous mechanisms of anti-inflammation uncovers novel chemical mediators: missing links to resolution , 2004, Histochemistry and Cell Biology.
[50] D. Gilroy,et al. 15-epi-lipoxin A4–mediated Induction of Nitric Oxide Explains How Aspirin Inhibits Acute Inflammation , 2004, The Journal of experimental medicine.
[51] P. Mukherjee,et al. Neuroprotectin D1: a docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[52] Adriano G. Rossi,et al. Inflammatory Resolution: new opportunities for drug discovery , 2004, Nature Reviews Drug Discovery.
[53] J. Uddin,et al. Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway , 2004, Nature Immunology.
[54] A. Sher,et al. Exogenous Pathogen and Plant 15-Lipoxygenase Initiate Endogenous Lipoxin A4 Biosynthesis , 2004, The Journal of experimental medicine.
[55] J. Mekalanos,et al. The opportunistic pathogen Pseudomonas aeruginosa carries a secretable arachidonate 15-lipoxygenase , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[56] P. Mukherjee,et al. Neuroprotectin D 1 : A docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress , 2004 .
[57] C. Clish,et al. Reduced Inflammation and Tissue Damage in Transgenic Rabbits Overexpressing 15-Lipoxygenase and Endogenous Anti-inflammatory Lipid Mediators 1 , 2003, The Journal of Immunology.
[58] Song‐Pyo Hong,et al. Novel Docosanoids Inhibit Brain Ischemia-Reperfusion-mediated Leukocyte Infiltration and Pro-inflammatory Gene Expression* , 2003, Journal of Biological Chemistry.
[59] J. Wallace,et al. A magic bullet for mucosal protection...and aspirin is the trigger! , 2003, Trends in pharmacological sciences.
[60] C. Serhan,et al. Aspirin-Triggered Lipoxin A4 and B4 Analogs Block Extracellular Signal-Regulated Kinase-Dependent TNF-α Secretion from Human T Cells 1 , 2003, The Journal of Immunology.
[61] C. Serhan,et al. Novel Docosatrienes and 17S-Resolvins Generated from Docosahexaenoic Acid in Murine Brain, Human Blood, and Glial Cells , 2003, The Journal of Biological Chemistry.
[62] C. Serhan,et al. Resolution of Inflammation: A New Paradigm for the Pathogenesis of Periodontal Diseases , 2003, Journal of dental research.
[63] P. Wood. Neuroinflammation : mechanisms and management , 2003 .
[64] V. Arroyo,et al. Aspirin (ASA) regulates 5‐lipoxygenase activity and peroxisome proliferator‐activated receptor α‐mediated CINC‐1 release in rat liver cells: novel actions of lipoxin A4 (LXA4) and ASA‐triggered 15‐epi‐LXA4 , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[65] A. Simopoulos. Omega-3 Fatty Acids in Inflammation and Autoimmune Diseases , 2002, Journal of the American College of Nutrition.
[66] C. Serhan,et al. Resolvins , 2002, The Journal of experimental medicine.
[67] N. Petasis,et al. Lipoxins, aspirin-triggered epi-lipoxins, lipoxin stable analogues, and the resolution of inflammation: stimulation of macrophage phagocytosis of apoptotic neutrophils in vivo. , 2002, Journal of the American Society of Nephrology : JASN.
[68] C. Serhan,et al. Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit peroxynitrite formation, NF-κB and AP-1 activation, and IL-8 gene expression in human leukocytes , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[69] Eugene Y. Kim,et al. Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A4 , 2002, Nature Medicine.
[70] J. Bousquet,et al. Lipoxins are potential endogenous antiinflammatory mediators in asthma. , 2002, American journal of respiratory and critical care medicine.
[71] A. Young,et al. Lipoxin A4 Analogs Attenuate Induction of Intestinal Epithelial Proinflammatory Gene Expression and Reduce the Severity of Dextran Sodium Sulfate-Induced Colitis1 , 2002, The Journal of Immunology.
[72] O. Levy,et al. Lipid mediator-induced expression of bactericidal/ permeability-increasing protein (BPI) in human mucosal epithelia , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[73] J. Kutok,et al. Novel lipid mediator regulators of endothelial cell proliferation and migration: aspirin-triggered-15R-lipoxin A(4) and lipoxin A(4). , 2002, The Journal of pharmacology and experimental therapeutics.
[74] A. Sher,et al. Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity , 2002, Nature Immunology.
[75] D. Basile,et al. Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-term function. , 2001, American journal of physiology. Renal physiology.
[76] Hee-Yong Kim,et al. Mechanisms of action of docosahexaenoic acid in the nervous system , 2001, Lipids.
[77] Charles N. Serhan,et al. Lipid mediator class switching during acute inflammation: signals in resolution , 2001, Nature Immunology.
[78] S Gelman,et al. Pathophysiology, Clinical Manifestations, and Prevention of Ischemia-Reperfusion Injury , 2001, Anesthesiology.
[79] C. Clish,et al. Novel Functional Sets of Lipid-Derived Mediators with Antiinflammatory Actions Generated from Omega-3 Fatty Acids via Cyclooxygenase 2–Nonsteroidal Antiinflammatory Drugs and Transcellular Processing , 2000, The Journal of experimental medicine.
[80] A. Fanning,et al. Lipoxin A4 antagonizes the mitogenic effects of leukotriene D4 in human renal mesangial cells. Differential activation of MAP kinases through distinct receptors. , 2000, The Journal of biological chemistry.
[81] J. Varga,et al. Lipoxin A4 Inhibits IL-1β-Induced IL-6, IL-8, and Matrix Metalloproteinase-3 Production in Human Synovial Fibroblasts and Enhances Synthesis of Tissue Inhibitors of Metalloproteinases1 , 2000, The Journal of Immunology.
[82] C. Serhan,et al. Cutting Edge: Lipoxin (LX) A4 and Aspirin-Triggered 15-Epi-LXA4 Block Allergen-Induced Eosinophil Trafficking1 , 2000, The Journal of Immunology.
[83] Hugh R. Brady,et al. Cutting Edge: Lipoxins Rapidly Stimulate Nonphlogistic Phagocytosis of Apoptotic Neutrophils by Monocyte-Derived Macrophages1 , 2000, The Journal of Immunology.
[84] C. Serhan,et al. HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY Anti-Inflammatory Actions of Lipoxin A 4 Stable Analogs Are Demonstrable in Human Whole Blood: Modulation of Leukocyte Adhesion Molecules and Inhibition of Neutrophil-Endothelial Interactions , 2016 .
[85] C. Serhan,et al. Identification of a human enterocyte lipoxin a receptor that is regulated by IL-13 and IFN-γ and inhibits TNF-α-induced IL-8 release , 1999 .
[86] C. Clish,et al. Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[87] Y. Kaneda,et al. Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[88] GISSI-Prevenzione Investigators,et al. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial , 1999, The Lancet.
[89] Roberto Marchioli,et al. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. , 1999 .
[90] M. Freeman,et al. Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion. , 1999, The Journal of clinical investigation.
[91] D. Gilroy,et al. Inducible cyclooxygenase may have anti-inflammatory properties , 1999, Nature Medicine.
[92] B. Levy,et al. Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a ‘stop’ signaling switch for aspirin‐triggered lipoxin A4 , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[93] C. Serhan,et al. Pathogen-induced chemokine secretion from model intestinal epithelium is inhibited by lipoxin A4 analogs. , 1998, The Journal of clinical investigation.
[94] C. Serhan,et al. Identification of a Human Enterocyte Lipoxin A4 Receptor That Is Regulated by Interleukin (IL)-13 and Interferon γ and Inhibits Tumor Necrosis Factor α–induced IL-8 Release , 1998, The Journal of experimental medicine.
[95] C. Serhan,et al. Characterization of human neutrophil and endothelial cell ligand-operated extracellular acidification rate by microphysiometry: impact of reoxygenation. , 1998, The Journal of pharmacology and experimental therapeutics.
[96] C. Clish,et al. Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues. , 1998, The Journal of clinical investigation.
[97] N. Morris,et al. The Fate of Cartilage Oligomeric Matrix Protein Is Determined by the Cell Type in the Case of a Novel Mutation in Pseudoachondroplasia* , 1997, The Journal of Biological Chemistry.
[98] A. M. Lefer,et al. Lipoxin A4 stable analogs inhibit leukocyte rolling and adherence in the rat mesenteric microvasculature: role of P-selectin. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[99] T. Takano,et al. Aspirin-triggered 15-Epi-Lipoxin A4 (LXA4) and LXA4 Stable Analogues Are Potent Inhibitors of Acute Inflammation: Evidence for Anti-inflammatory Receptors , 1997, The Journal of experimental medicine.
[100] T. Takano,et al. Lipoxin A4 Stable Analogs Are Potent Mimetics That Stimulate Human Monocytes and THP-1 Cells via a G-protein-linked Lipoxin A4 Receptor* , 1997, The Journal of Biological Chemistry.
[101] J. Cornhill,et al. Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development. , 1996, The Journal of clinical investigation.
[102] C. Serhan,et al. Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells. , 1996, Journal of immunology.
[103] C. Serhan,et al. Lipoxin A4 and B4 are potent stimuli for human monocyte migration and adhesion: selective inactivation by dehydrogenation and reduction , 1996, The Journal of experimental medicine.
[104] G. Majno,et al. Cells, tissues, and disease : principles of general pathology , 1996 .
[105] C. Serhan,et al. Lipoxin A4 receptor activation is distinct from that of the formyl peptide receptor in myeloid cells: inhibition of CD11/18 expression by lipoxin A4-lipoxin A4 receptor interaction. , 1995, Biochemistry.
[106] I. Akritopoulou‐Zanze,et al. Design of lipoxin A4 stable analogs that block transmigration and adhesion of human neutrophils. , 1995, Biochemistry.
[107] C. Serhan,et al. Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[108] T. Williams,et al. Pro-inflammatory and anti-inflammatory effects of the stable prostaglandin D2 analogue, ZK 118.182. , 1994, European journal of pharmacology.
[109] C. Serhan,et al. Lipoxin A4 modulates transmigration of human neutrophils across intestinal epithelial monolayers. , 1993, The Journal of clinical investigation.
[110] C. Serhan,et al. Lipoxin generation by permeabilized human platelets. , 1992, Biochemistry.
[111] C. Serhan,et al. Formation of lipoxins and leukotrienes during receptor-mediated interactions of human platelets and recombinant human granulocyte/macrophage colony-stimulating factor-primed neutrophils , 1990, The Journal of experimental medicine.
[112] B. Spur,et al. Lipoxin A4 and lipoxin B4 inhibit chemotactic responses of human neutrophils stimulated by leukotriene B4 and N-formyl-L-methionyl-L-leucyl-L-phenylalanine. , 1989, Clinical science.
[113] M. Brezinski,et al. Lipoxins stimulate prostacyclin generation by human endothelial cells , 1989, FEBS letters.
[114] J. Haeggström,et al. Transcellular conversion of endogenous arachidonic acid to lipoxins in mixed human platelet-granulocyte suspensions. , 1988, Biochemical and biophysical research communications.
[115] W. Lands,et al. Proceedings of the AOCS Short Course on Polyunsaturated Fatty Acids and Eicosanoids , 1987 .
[116] N. Bazan,et al. Docosahexaenoic acid (22:6, n-3) is metabolized to lipoxygenase reaction products in the retina. , 1984, Biochemical and biophysical research communications.
[117] I. Morita,et al. Increased arachidonic acid content in platelet phospholipids from diabetic patients. , 1983, Prostaglandins, leukotrienes, and medicine.
[118] B. Samuelsson. Leukotrienes: a new class of mediators of immediate hypersensitivity reactions and inflammation. , 1983, Advances in prostaglandin, thromboxane, and leukotriene research.
[119] M. Peck,et al. Mechanisms underlying inflammatory edema: the importance of synergism between prostaglandins, leukotrienes, and complement-derived peptides. , 1983, Advances in prostaglandin, thromboxane, and leukotriene research.
[120] Nobelstiftelsen. Les Prix Nobel : Nobel Prizes, presentations, biographies and lectures , 1982 .
[121] P. Ward,et al. Suppression of acute and chronic inflammation by orally administered prostaglandins. , 1981, Arthritis and rheumatism.
[122] G. Weissmann,et al. Release of inflammatory mediators from stimulated neutrophils. , 1980, The New England journal of medicine.