Very low oxygen concentration (0.1%) reveals two FDCP-Mix cell subpopulations that differ by their cell cycling, differentiation and p27KIP1 expression

[1]  Pernilla Eliasson,et al.  Hypoxia mediates low cell-cycle activity and increases the proportion of long-term-reconstituting hematopoietic stem cells during in vitro culture. , 2010, Experimental hematology.

[2]  Matthias Schieker,et al.  Hypoxic preconditioning of human mesenchymal stem cells overcomes hypoxia-induced inhibition of osteogenic differentiation. , 2010, Tissue engineering. Part A.

[3]  Guoqiang Chen,et al.  Hypoxia-HIF-1alpha-C/EBPalpha/Runx1 signaling in leukemic cell differentiation. , 2009, Pathophysiology : the official journal of the International Society for Pathophysiology.

[4]  P. Schaaf,et al.  O2 Level Controls Hematopoietic Circulating Progenitor Cells Differentiation into Endothelial or Smooth Muscle Cells , 2009, PloS one.

[5]  Zoran Ivanovic,et al.  Low oxygen concentration as a general physiologic regulator of erythropoiesis beyond the EPO-related downstream tuning and a tool for the optimization of red blood cell production ex vivo. , 2009, Experimental hematology.

[6]  K. Eckardt,et al.  HIF-1 or HIF-2 induction is sufficient to achieve cell cycle arrest in NIH3T3 mouse fibroblasts independent from hypoxia , 2009, Cell cycle.

[7]  Zoran Ivanovic,et al.  Hypoxia or in situ normoxia: The stem cell paradigm , 2009, Journal of cellular physiology.

[8]  Jiannis Ragoussis,et al.  Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts , 2009, The Journal of Biological Chemistry.

[9]  Z. Ivanovic Physiological, ex vivo cell oxygenation is necessary for a true insight into cytokine biology. , 2009, European cytokine network.

[10]  Guoqiang Chen,et al.  Hypoxia-inducible factor-1α-induced differentiation of myeloid leukemic cells is its transcriptional activity independent , 2008, Oncogene.

[11]  V. Praloran,et al.  Interleukin‐6 (IL‐6) and low O2 concentration (1%) synergize to improve the maintenance of hematopoietic stem cells (pre‐CFC) , 2007, Journal of cellular physiology.

[12]  M. Olivotto,et al.  Severe Hypoxia Defines Heterogeneity and Selects Highly Immature Progenitors Within Clonal Erythroleukemia Cells , 2007, Stem cells.

[13]  K. Parmar,et al.  Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia , 2007, Proceedings of the National Academy of Sciences.

[14]  O. Bernard,et al.  Functional analyses of the TEL-ARNT fusion protein underscores a role for oxygen tension in hematopoietic cellular differentiation , 2006, Oncogene.

[15]  M. Olivotto,et al.  Hypoxia suppresses BCR/Abl and selects imatinib-insensitive progenitors within clonal CML populations , 2006, Leukemia.

[16]  J. Pouysségur,et al.  The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha. , 2006, Cancer research.

[17]  V. Praloran,et al.  Very Low O2 Concentration (0.1%) Favors G0 Return of Dividing CD34+ Cells , 2006, Stem cells.

[18]  James M. Roberts,et al.  A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppression. , 2006, Genes & development.

[19]  J. Hogenesch,et al.  Gene expression profiling of hypoxia signaling in human hepatocellular carcinoma cells. , 2005, Physiological genomics.

[20]  Amato J Giaccia,et al.  The biology of hypoxia: the role of oxygen sensing in development, normal function, and disease. , 2004, Genes & development.

[21]  F. Lacombe,et al.  Simultaneous Maintenance of Human Cord Blood SCID‐Repopulating Cells and Expansion of Committed Progenitors at Low O2 Concentration (3%) , 2004, Stem cells.

[22]  W. Liu,et al.  Cobalt chloride and low oxygen tension trigger differentiation of acute myeloid leukemic cells: possible mediation of hypoxia-inducible factor-1α , 2003, Leukemia.

[23]  J. Pouysségur,et al.  HIF prolyl‐hydroxylase 2 is the key oxygen sensor setting low steady‐state levels of HIF‐1α in normoxia , 2003, The EMBO journal.

[24]  M. Simon,et al.  Expansion of human SCID-repopulating cells under hypoxic conditions. , 2003, The Journal of clinical investigation.

[25]  R. Rickert,et al.  Hypoxia-Inducible Factor 1 (cid:2) Is Essential for Cell Cycle Arrest during Hypoxia , 2002 .

[26]  V. Praloran,et al.  Hypoxia Modifies Proliferation and Differentiation of CD34+ CML Cells , 2002, Stem cells.

[27]  E. Lam,et al.  Control of Cell Cycle Exit and Entry by Protein Kinase B-Regulated Forkhead Transcription Factors , 2002, Molecular and Cellular Biology.

[28]  V. Praloran,et al.  Hypoxia maintains and interleukin-3 reduces the pre-colony-forming cell potential of dividing CD34(+) murine bone marrow cells. , 2002, Experimental hematology.

[29]  W M Miller,et al.  Modeling pO(2) distributions in the bone marrow hematopoietic compartment. II. Modified Kroghian models. , 2001, Biophysical journal.

[30]  W M Miller,et al.  Modeling pO(2) distributions in the bone marrow hematopoietic compartment. I. Krogh's model. , 2001, Biophysical journal.

[31]  S. Nilsson,et al.  Spatial localization of transplanted hemopoietic stem cells: inferences for the localization of stem cell niches. , 2001, Blood.

[32]  P. Adams Regulation of the retinoblastoma tumor suppressor protein by cyclin/cdks. , 2001, Biochimica et biophysica acta.

[33]  Chi V. Dang,et al.  Hypoxia Inhibits G1/S Transition through Regulation of p27 Expression* , 2001, The Journal of Biological Chemistry.

[34]  V. Praloran,et al.  Primitive human HPCs are better maintained and expanded in vitro at 1 percent oxygen than at 20 percent , 2000, Transfusion.

[35]  V. Praloran,et al.  The expansion of murine bone marrow cells preincubated in hypoxia as an in vitro indicator of their marrow-repopulating ability , 2000, Leukemia.

[36]  D. Fisher,et al.  Regulation of Proliferation-Survival Decisions during Tumor Cell Hypoxia , 1998, Molecular and Cellular Biology.

[37]  G. Semenza,et al.  Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension. , 1996, The American journal of physiology.

[38]  J. Bartek,et al.  Abrogation of p27Kip1 by cDNA Antisense Suppresses Quiescence (G0 State) in Fibroblasts* , 1996, The Journal of Biological Chemistry.

[39]  James M. Roberts,et al.  Requirement of p27Kip1 for Restriction Point Control of the Fibroblast Cell Cycle , 1996, Science.

[40]  T. Dexter,et al.  The role of hemopoietic growth factors in self-renewal and differentiation of IL-3-dependent multipotential stem cells. , 1990, Growth factors.

[41]  E. Tøndevold,et al.  Observations on long bone medullary pressures in relation to arterial PO2, PCO2 and pH in the anaesthetized dog. , 1979, Acta orthopaedica Scandinavica.