Autophagy in neuroinflammatory diseases.

[1]  P. Boya,et al.  Lysosomal cell death mechanisms in aging , 2016, Ageing Research Reviews.

[2]  C. Selmi,et al.  Current trends in autoimmunity and the nervous system. , 2016, Journal of autoimmunity.

[3]  L. Shulman,et al.  Clinical subtypes and genetic heterogeneity: of lumping and splitting in Parkinson disease. , 2016, Current opinion in neurology.

[4]  G. Bu,et al.  TREMs in Alzheimer's disease: Genetic and clinical investigations. , 2016, Clinica chimica acta; international journal of clinical chemistry.

[5]  A. Ittner SITE-SPECIFIC PHOSPHORYLATION OF TAU INHIBITS AMYLOID-β TOXICITY IN ALZHEIMER’S MICE , 2016, Alzheimer's & Dementia.

[6]  S. Muller,et al.  Autoimmunity, neuroinflammation, pathogen load: A decisive crosstalk in neuropsychiatric SLE. , 2016, Journal of autoimmunity.

[7]  M. Govoni,et al.  The diagnosis and clinical management of the neuropsychiatric manifestations of lupus. , 2016, Journal of autoimmunity.

[8]  M. Petri,et al.  Immunomodulators in SLE: Clinical evidence and immunologic actions. , 2016, Journal of autoimmunity.

[9]  R. Barker,et al.  Neuroendocrine abnormalities in Parkinson's disease , 2016, Journal of Neurology, Neurosurgery & Psychiatry.

[10]  Tao Wu,et al.  The study of brain functional connectivity in Parkinson’s disease , 2016, Translational Neurodegeneration.

[11]  K. Bourzac Diagnosis: Warning signs , 2016, Nature.

[12]  K. Chand,et al.  Recent progress in repositioning Alzheimer's disease drugs based on a multitarget strategy. , 2016, Future medicinal chemistry.

[13]  D. B. Vieira,et al.  Getting into the brain: liposome-based strategies for effective drug delivery across the blood–brain barrier , 2016, International journal of nanomedicine.

[14]  K. Cadwell Crosstalk between autophagy and inflammatory signalling pathways: balancing defence and homeostasis , 2016, Nature Reviews Immunology.

[15]  H. Ryu,et al.  Astrocytes and Microglia as Non-cell Autonomous Players in the Pathogenesis of ALS , 2016, Experimental Neurobiology.

[16]  C. Putterman,et al.  The role of B cells and autoantibodies in neuropsychiatric lupus. , 2016, Autoimmunity reviews.

[17]  C. Hartmann,et al.  Deep Brain Stimulation in Huntington’s Disease—Preliminary Evidence on Pathophysiology, Efficacy and Safety , 2016, Brain sciences.

[18]  M. Xilouri,et al.  Impairment of chaperone-mediated autophagy induces dopaminergic neurodegeneration in rats , 2016, Autophagy.

[19]  M. Vila,et al.  The Parkinson Disease Mitochondrial Hypothesis , 2016, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

[20]  H. Adachi,et al.  Natural Compounds Preventing Neurodegenerative Diseases Through Autophagic Activation. , 2016, Journal of UOEH.

[21]  Mandar S Jog,et al.  An update on the diagnosis and treatment of Parkinson disease , 2016, Canadian Medical Association Journal.

[22]  J. Brotchie,et al.  Treatment with Trehalose Prevents Behavioral and Neurochemical Deficits Produced in an AAV α-Synuclein Rat Model of Parkinson’s Disease , 2016, Molecular Neurobiology.

[23]  Andrew B Singleton,et al.  Genetics in Parkinson disease: Mendelian versus non‐Mendelian inheritance , 2016, Journal of neurochemistry.

[24]  Wenting Zhu,et al.  Autophagy is involved in the pathogenesis of experimental autoimmune neuritis in rats , 2016, Neuroreport.

[25]  F. Mahn,et al.  Resveratrol reduces amyloid-beta (Aβ1–42)-induced paralysis through targeting proteostasis in an Alzheimer model of Caenorhabditis elegans , 2016, European Journal of Nutrition.

[26]  Melvyn W B Zhang,et al.  A meta-analysis of serum and cerebrospinal fluid autoantibodies in neuropsychiatric systemic lupus erythematosus. , 2016, Autoimmunity reviews.

[27]  Harald Sontheimer,et al.  Glia as drivers of abnormal neuronal activity , 2015, Nature Neuroscience.

[28]  D. Troost,et al.  NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients , 2015, Glia.

[29]  J. Blum,et al.  A central role for HSC70 in regulating antigen trafficking and MHC class II presentation. , 2015, Molecular immunology.

[30]  Zhen Zhao,et al.  Establishment and Dysfunction of the Blood-Brain Barrier , 2015, Cell.

[31]  L. Citterio,et al.  TRPC6 gene variants and neuropsychiatric lupus , 2015, Journal of Neuroimmunology.

[32]  K. Myhr,et al.  Disease-modifying treatments for multiple sclerosis – a review of approved medications , 2015, European journal of neurology.

[33]  Zhigui Li,et al.  Triptolide Inhibited Cytotoxicity of Differentiated PC12 Cells Induced by Amyloid-Beta25–35 via the Autophagy Pathway , 2015, PloS one.

[34]  Jill A Hollenbach,et al.  The immunogenetics of multiple sclerosis: A comprehensive review. , 2015, Journal of autoimmunity.

[35]  H. Reichmann,et al.  Pathogenesis of Parkinson disease—the gut–brain axis and environmental factors , 2015, Nature Reviews Neurology.

[36]  Ji Eun Lee,et al.  Role of autophagy in the pathogenesis of amyotrophic lateral sclerosis. , 2015, Biochimica et biophysica acta.

[37]  J. Atkin,et al.  Golgi fragmentation in amyotrophic lateral sclerosis, an overview of possible triggers and consequences , 2015, Front. Neurosci..

[38]  F. Rizzi,et al.  EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism , 2015, Scientific Reports.

[39]  Steffen Jung,et al.  Microglia Plasticity During Health and Disease: An Immunological Perspective. , 2015, Trends in immunology.

[40]  J. Harper,et al.  The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy. , 2015, Molecular cell.

[41]  I. Blair,et al.  ALS-associated mutant FUS inhibits macroautophagy which is restored by overexpression of Rab1 , 2015, Cell Death Discovery.

[42]  R. Nixon,et al.  Presenilin 1 Maintains Lysosomal Ca(2+) Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification. , 2015, Cell reports.

[43]  C. Mclean,et al.  Rab1-dependent ER–Golgi transport dysfunction is a common pathogenic mechanism in SOD1, TDP-43 and FUS-associated ALS , 2015, Acta Neuropathologica.

[44]  J. Burman,et al.  The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy , 2015, Nature.

[45]  E. Masliah,et al.  Autophagy in Alzheimer’s disease , 2015, Reviews in the neurosciences.

[46]  Shihua Li,et al.  Therapeutic Effect of Berberine on Huntington’s Disease Transgenic Mouse Model , 2015, PloS one.

[47]  Y. Li,et al.  Trehalose decreases mutant SOD1 expression and alleviates motor deficiency in early but not end-stage amyotrophic lateral sclerosis in a SOD1-G93A mouse model , 2015, Neuroscience.

[48]  D. Rubinsztein,et al.  Therapeutic targeting of autophagy in neurodegenerative and infectious diseases , 2015, The Journal of experimental medicine.

[49]  Y. Lo,et al.  FRI0412 Symptoms of Attention Deficit Hyperactivity Disorder in Patients with Systemic Lupus Erythematosus , 2015 .

[50]  J. Mintern,et al.  Modulation of antigen presentation by intracellular trafficking. , 2015, Current opinion in immunology.

[51]  Angeleen Fleming,et al.  Compromised autophagy and neurodegenerative diseases , 2015, Nature Reviews Neuroscience.

[52]  S. Muller,et al.  Manipulating Autophagic Processes in Autoimmune Diseases: A Special Focus on Modulating Chaperone-Mediated Autophagy, an Emerging Therapeutic Target , 2015, Front. Immunol..

[53]  H. Houlden,et al.  Exome sequencing uncovers hidden pathways in familial and sporadic ALS , 2015, Nature Neuroscience.

[54]  Junying Yuan,et al.  Autophagy in Neurodegenerative Diseases: From Mechanism to Therapeutic Approach , 2015, Molecules and cells.

[55]  Ju-Hee Lee,et al.  EGCG-mediated autophagy flux has a neuroprotection effect via a class III histone deacetylase in primary neuron cells , 2015, Oncotarget.

[56]  Paulo Pereira,et al.  Autophagy and ubiquitination in cardiovascular diseases. , 2015, DNA and cell biology.

[57]  O. Garaschuk,et al.  Neuroinflammation in Alzheimer's disease , 2015, The Lancet Neurology.

[58]  A. Echaniz-Laguna,et al.  A metabolic switch toward lipid use in glycolytic muscle is an early pathologic event in a mouse model of amyotrophic lateral sclerosis , 2015, EMBO molecular medicine.

[59]  S. Muller,et al.  Resetting the autoreactive immune system with a therapeutic peptide in lupus , 2015, Lupus.

[60]  J. Chapman,et al.  Neuropsychiatric lupus: a mosaic of clinical presentations , 2015, BMC Medicine.

[61]  Yong Tae Kwon,et al.  Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies , 2015, Experimental & Molecular Medicine.

[62]  A. Cuervo,et al.  Modulation of deregulated chaperone-mediated autophagy by a phosphopeptide , 2015, Autophagy.

[63]  M. Hayden,et al.  Autophagy in Huntington disease and huntingtin in autophagy , 2015, Trends in Neurosciences.

[64]  L. Kremer,et al.  Characterization of a new rat model for chronic inflammatory demyelinating polyneuropathies , 2015, Journal of Neuroimmunology.

[65]  P. Codogno,et al.  Development of autophagy inducers in clinical medicine. , 2015, The Journal of clinical investigation.

[66]  S. Cenci Autophagy, a new determinant of plasma cell differentiation and antibody responses. , 2014, Molecular immunology.

[67]  Y. Nakagawa,et al.  Role of Microglial M1/M2 Polarization in Relapse and Remission of Psychiatric Disorders and Diseases , 2014, Pharmaceuticals.

[68]  C. Hetz,et al.  Targeting autophagy in neurodegenerative diseases. , 2014, Trends in pharmacological sciences.

[69]  Haijian Wu,et al.  Crosstalk Between Macroautophagy and Chaperone-Mediated Autophagy: Implications for the Treatment of Neurological Diseases , 2014, Molecular Neurobiology.

[70]  Y. Li,et al.  Downregulation of PI3K/Akt/mTOR signaling pathway in curcumin-induced autophagy in APP/PS1 double transgenic mice. , 2014, European journal of pharmacology.

[71]  S. Muller,et al.  Pharmacological regulators of autophagy and their link with modulators of lupus disease , 2014, British journal of pharmacology.

[72]  S. Muller,et al.  Neuropsychiatric systemic lupus erythematosus: pathogenesis and biomarkers , 2014, Nature Reviews Neurology.

[73]  N. Kowall,et al.  Therapeutic targeting of epigenetic components in amyotrophic lateral sclerosis (ALS). , 2014, Current medicinal chemistry.

[74]  R. Pacheco,et al.  Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases , 2014, Journal of Neuroimmunology.

[75]  A. Cuervo,et al.  Chaperone mediated autophagy regulates T cell responses through targeted degradation of negative regulators of T cell activation , 2014, Nature Immunology.

[76]  S. Muller,et al.  Neuropsychiatric systemic lupus erythematosus and cognitive dysfunction: the MRL-lpr mouse strain as a model. , 2014, Autoimmunity reviews.

[77]  N. Eissa,et al.  Deficiency of Autophagy in Dendritic Cells Protects against Experimental Autoimmune Encephalomyelitis* , 2014, The Journal of Biological Chemistry.

[78]  H. Weiner,et al.  Differential roles of microglia and monocytes in the inflamed central nervous system , 2014, The Journal of experimental medicine.

[79]  J. Lou,et al.  Hypercaloric enteral nutrition in patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled phase 2 trial , 2014, The Lancet.

[80]  S. Finkbeiner,et al.  Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models , 2014, Nature chemical biology.

[81]  J. Hanly Diagnosis and management of neuropsychiatric SLE , 2014, Nature Reviews Rheumatology.

[82]  G. Kroemer,et al.  Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis , 2014, Autophagy.

[83]  A. Laties,et al.  Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer’s disease-linked presenilin 1 A246E mutation can be reversed with cAMP , 2014, Neuroscience.

[84]  M. Mena,et al.  Trehalose Reverses Cell Malfunction in Fibroblasts from Normal and Huntington's Disease Patients Caused by Proteosome Inhibition , 2014, PloS one.

[85]  S. Muller,et al.  The importance of implementing proper selection of excipients in lupus clinical trials , 2014, Lupus.

[86]  P. Gleeson,et al.  C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking , 2014, Human molecular genetics.

[87]  T. Vyse,et al.  Autophagy is activated in systemic lupus erythematosus and required for plasmablast development , 2014, Annals of the rheumatic diseases.

[88]  P. Szewczyk,et al.  In vivo evaluation of brain damage in the course of systemic lupus erythematosus using magnetic resonance spectroscopy, perfusion-weighted and diffusion-tensor imaging , 2014, Lupus.

[89]  Shang-Der Chen,et al.  Resveratrol Partially Prevents Rotenone-Induced Neurotoxicity in Dopaminergic SH-SY5Y Cells through Induction of Heme Oxygenase-1 Dependent Autophagy , 2014, International journal of molecular sciences.

[90]  S. Cessie,et al.  Mortality in neuropsychiatric systemic lupus erythematosus (NPSLE) , 2014, Lupus.

[91]  N. Mizushima,et al.  Autophagy and human diseases , 2013, Cell Research.

[92]  S. Snyder,et al.  Rhes, a Striatal-selective Protein Implicated in Huntington Disease, Binds Beclin-1 and Activates Autophagy* , 2013, The Journal of Biological Chemistry.

[93]  J. Ule,et al.  Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic , 2013, Cell reports.

[94]  A. Cuervo,et al.  Chaperone-mediated autophagy: roles in disease and aging , 2013, Cell Research.

[95]  H. Wood Neurodegenerative disease: C9orf72 RNA foci—a therapeutic target for ALS and FTD? , 2013, Nature Reviews Neurology.

[96]  Liang Liu,et al.  Onjisaponin B Derived from Radix Polygalae Enhances Autophagy and Accelerates the Degradation of Mutant α-Synuclein and Huntingtin in PC-12 Cells , 2013, International journal of molecular sciences.

[97]  F. Stricher,et al.  HSPA8/HSC70 chaperone protein , 2013, Autophagy.

[98]  M. Xilouri,et al.  LAMP2A as a therapeutic target in Parkinson disease , 2013, Autophagy.

[99]  Núria Bargalló,et al.  Neuropsychiatric systemic lupus erythematosus: magnetic resonance imaging findings and correlation with clinical and immunological features. , 2013, Autoimmunity reviews.

[100]  S. Sarkar,et al.  Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers. , 2013, Biochemical Society transactions.

[101]  Shizuo Akira,et al.  Autophagy in infection, inflammation and immunity , 2013, Nature Reviews Immunology.

[102]  P. Sachdev,et al.  Alpha-Synuclein Transmission and Mitochondrial Toxicity in Primary Human Foetal Enteric Neurons In Vitro , 2013, Neurotoxicity Research.

[103]  Z. Tao,et al.  Epigallocatechin-gallate (EGCG) regulates autophagy in human retinal pigment epithelial cells: a potential role for reducing UVB light-induced retinal damage. , 2013, Biochemical and biophysical research communications.

[104]  D. Boumpas,et al.  Pathogenesis and treatment of CNS lupus , 2013, Current opinion in rheumatology.

[105]  Hualiang Jiang,et al.  Arctigenin Effectively Ameliorates Memory Impairment in Alzheimer's Disease Model Mice Targeting Both β-Amyloid Production and Clearance , 2013, The Journal of Neuroscience.

[106]  D. Cleveland,et al.  Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis , 2013, Neuron.

[107]  F. Middleton,et al.  HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE , 2013, Annals of the rheumatic diseases.

[108]  V. Parpura,et al.  Epigallocatechin Gallate (EGCG) Stimulates Autophagy in Vascular Endothelial Cells , 2013, The Journal of Biological Chemistry.

[109]  Christine E. Becker,et al.  CD36 coordinates NLRP3 inflammasome activation by facilitating the intracellular nucleation from soluble to particulate ligands in sterile inflammation , 2013, Nature Immunology.

[110]  C. Hetz,et al.  Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons , 2013, Autophagy.

[111]  Sooyeon Lee,et al.  Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification , 2013, The European journal of neuroscience.

[112]  Keith A. Johnson,et al.  CD33 Alzheimer’s disease locus: Altered monocyte function and amyloid biology , 2013, Nature Neuroscience.

[113]  Bradley T. Hyman,et al.  Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta , 2013, Neuron.

[114]  Peter Cresswell,et al.  Pathways of antigen processing. , 2013, Annual review of immunology.

[115]  Wim Robberecht,et al.  The changing scene of amyotrophic lateral sclerosis , 2013, Nature Reviews Neuroscience.

[116]  A. Singleton,et al.  TREM2 variants in Alzheimer's disease. , 2013, The New England journal of medicine.

[117]  A. McKee,et al.  Expression of Taurine Transporter (TauT) is Modulated by Heat Shock Factor 1 (HSF1) in Motor Neurons of ALS , 2012, Molecular Neurobiology.

[118]  J. Gómez-Reino,et al.  Lupuzor/P140 peptide in patients with systemic lupus erythematosus: a randomised, double-blind, placebo-controlled phase IIb clinical trial , 2012, Annals of the rheumatic diseases.

[119]  E. Mandelkow,et al.  Autophagic degradation of tau in primary neurons and its enhancement by trehalose , 2012, Neurobiology of Aging.

[120]  S. Muller,et al.  Peptide-based approaches to treat lupus and other autoimmune diseases. , 2012, Journal of autoimmunity.

[121]  S. Lee,et al.  The efficacy of brain 18 F-fluorodeoxyglucose positron emission tomography in neuropsychiatric lupus patients with normal brain magnetic resonance imaging findings , 2012, Lupus.

[122]  A. Perl,et al.  T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[123]  S. Hadano,et al.  Dysregulation of the Autophagy-Endolysosomal System in Amyotrophic Lateral Sclerosis and Related Motor Neuron Diseases , 2012, Neurology research international.

[124]  A. Björklund,et al.  Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo , 2012, PloS one.

[125]  R. Ho,et al.  A prospective functional MRI study for executive function in patients with systemic lupus erythematosus without neuropsychiatric symptoms. , 2012, Seminars in arthritis and rheumatism.

[126]  C. Putterman,et al.  Autoantibodies in lupus: culprits or passive bystanders? , 2012, Autoimmunity reviews.

[127]  A. Korganow,et al.  Macroautophagy is deregulated in murine and human lupus T lymphocytes , 2012, Autophagy.

[128]  D. Klionsky,et al.  Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) , 2012, Autophagy.

[129]  W. Malorni,et al.  Role of autophagy in immunity and autoimmunity, with a special focus on systemic lupus erythematosus , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[130]  Robert Clarke,et al.  Guidelines for the use and interpretation of assays for monitoring autophagy , 2012 .

[131]  F. Cecconi,et al.  Aβ Toxicity in Alzheimer's Disease , 2012, Molecular Neurobiology.

[132]  F. Leeuwen,et al.  The ubiquitin proteasome system in neurodegenerative diseases: Culprit, accomplice or victim? , 2012, Progress in Neurobiology.

[133]  D. Rubinsztein,et al.  Control of autophagy as a therapy for neurodegenerative disease , 2012, Nature Reviews Neurology.

[134]  W. Le,et al.  Autophagy dysregulation in amyotrophic lateral sclerosis , 2012, Journal of the Neurological Sciences.

[135]  Han-Ming Shen,et al.  Isorhynchophylline, a natural alkaloid, promotes the degradation of alpha-synuclein in neuronal cells via inducing autophagy , 2012, Autophagy.

[136]  Masaaki Komatsu,et al.  Autophagy: Renovation of Cells and Tissues , 2011, Cell.

[137]  Minesh Kapadia,et al.  Autoimmune and inflammatory mechanisms of CNS damage , 2011, Progress in Neurobiology.

[138]  R. Faull,et al.  Population-specific expression analysis (PSEA) reveals molecular changes in diseased brain , 2011, Nature Methods.

[139]  David Heckerman,et al.  A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD , 2011, Neuron.

[140]  D. Geschwind,et al.  Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS , 2011, Neuron.

[141]  M. Prescott,et al.  Microautophagy in mammalian cells: Revisiting a 40-year-old conundrum , 2011, Autophagy.

[142]  M. Hashefi,et al.  PET/CT imaging in systemic lupus erythematosus , 2011, Annals of the New York Academy of Sciences.

[143]  P. Gaffney,et al.  Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort , 2011, Genes and Immunity.

[144]  Hong Zhang,et al.  Genetic association of PRDM1-ATG5 intergenic region and autophagy with systemic lupus erythematosus in a Chinese population , 2011, Annals of the rheumatic diseases.

[145]  S. Sasaki Autophagy in Spinal Cord Motor Neurons in Sporadic Amyotrophic Lateral Sclerosis , 2011, Journal of neuropathology and experimental neurology.

[146]  Sung-soo Kim,et al.  Suppression of autophagy and activation of glycogen synthase kinase 3beta facilitate the aggregate formation of tau. , 2011, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.

[147]  M. Mena,et al.  The accumulation of neurotoxic proteins, induced by proteasome inhibition, is reverted by trehalose, an enhancer of autophagy, in human neuroblastoma cells , 2011, Neurochemistry International.

[148]  Annette Lee,et al.  Risk Alleles for Systemic Lupus Erythematosus in a Large Case-Control Collection and Associations with Clinical Subphenotypes , 2011, PLoS genetics.

[149]  Sudarshan C. Upadhya,et al.  Role of ubiquitin-proteasome-mediated proteolysis in nervous system disease. , 2011, Biochimica et biophysica acta.

[150]  A. Ludolph,et al.  Energy metabolism in amyotrophic lateral sclerosis , 2011, The Lancet Neurology.

[151]  C. Ross,et al.  Huntington's disease: from molecular pathogenesis to clinical treatment , 2011, The Lancet Neurology.

[152]  A. Caccamo,et al.  Naturally Secreted Amyloid-β Increases Mammalian Target of Rapamycin (mTOR) Activity via a PRAS40-mediated Mechanism* , 2011, The Journal of Biological Chemistry.

[153]  C. Oliveira,et al.  Mitochondrial Dysfunction: The Road to Alpha-Synuclein Oligomerization in PD , 2011, Parkinson's disease.

[154]  Jeroen van der Grond,et al.  Tract-based spatial statistics on diffusion tensor imaging in systemic lupus erythematosus reveals localized involvement of white matter tracts. , 2010, Arthritis and rheumatism.

[155]  Jin Zhou,et al.  Distribution of Th17 cells and Th1 cells in peripheral blood and cerebrospinal fluid in chronic inflammatory demyelinating polyradiculoneuropathy , 2010, Journal of the peripheral nervous system : JPNS.

[156]  Steven Finkbeiner,et al.  A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model , 2010, Proceedings of the National Academy of Sciences.

[157]  A. Cuervo,et al.  Identification of regulators of chaperone-mediated autophagy. , 2010, Molecular cell.

[158]  J. Ioannidis,et al.  EULAR recommendations for the management of systemic lupus erythematosus with neuropsychiatric manifestations: report of a task force of the EULAR standing committee for clinical affairs , 2010, Annals of the rheumatic diseases.

[159]  W. Beaino,et al.  Thiopalmitoylated peptides from the peripheral nervous system myelin p0 protein: synthesis, characterization, and neuritogenic properties. , 2010, Bioconjugate chemistry.

[160]  L. Tong,et al.  Age at onset in Huntington’s disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7 , 2010, Human Genetics.

[161]  G. Landreth,et al.  The role of microglia in amyloid clearance from the AD brain , 2010, Journal of Neural Transmission.

[162]  D. Boumpas,et al.  Pathogenesis, diagnosis and management of neuropsychiatric SLE manifestations , 2010, Nature Reviews Rheumatology.

[163]  C. Sommer,et al.  Chronic inflammatory demyelinating polyradiculoneuropathy: diagnostic and therapeutic challenges for a treatable condition , 2010, The Lancet Neurology.

[164]  D. Rubinsztein,et al.  Chemical Inducers of Autophagy That Enhance the Clearance of Mutant Proteins in Neurodegenerative Diseases , 2010, The Journal of Biological Chemistry.

[165]  G. Papadimitriou,et al.  The neuropsychiatry of multiple sclerosis: Focus on disorders of mood, affect and behaviour , 2010, International review of psychiatry.

[166]  K. Moore,et al.  CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer , 2009, Nature Immunology.

[167]  D. Cleveland,et al.  Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond , 2009, The Journal of cell biology.

[168]  M. Ferrari,et al.  TREX1 gene variant in neuropsychiatric systemic lupus erythematosus , 2009, Annals of the rheumatic diseases.

[169]  E. Masliah,et al.  Beclin 1 Gene Transfer Activates Autophagy and Ameliorates the Neurodegenerative Pathology in α-Synuclein Models of Parkinson's and Lewy Body Diseases , 2009, The Journal of Neuroscience.

[170]  B. Ganetzky,et al.  Autophagy promotes synapse development in Drosophila , 2009, The Journal of cell biology.

[171]  P. Carvey,et al.  The blood–brain barrier in neurodegenerative disease: a rhetorical perspective , 2009, Journal of neurochemistry.

[172]  B. Volpe,et al.  Losing your nerves? Maybe it's the antibodies , 2009, Nature Reviews Immunology.

[173]  W. Seaman,et al.  A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia , 2009, Journal of neurochemistry.

[174]  C. Langefeld,et al.  Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies , 2009, Nature Reviews Genetics.

[175]  Alain Van Dorsselaer,et al.  The Spliceosomal Phosphopeptide P140 Controls the Lupus Disease by Interacting with the HSC70 Protein and via a Mechanism Mediated by γδ T Cells , 2009, PloS one.

[176]  V. Crotzer,et al.  Autophagy and Its Role in MHC-Mediated Antigen Presentation1 , 2009, The Journal of Immunology.

[177]  G. Robertson,et al.  Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis , 2009, Autophagy.

[178]  T. Tomoda,et al.  Unc-51 Controls Active Zone Density and Protein Composition by Downregulating ERK Signaling , 2009, The Journal of Neuroscience.

[179]  S. Muller,et al.  Spliceosomal peptide P140 for immunotherapy of systemic lupus erythematosus: results of an early phase II clinical trial. , 2008, Arthritis and rheumatism.

[180]  S. Przedborski,et al.  Oxidative Stress in Parkinson's Disease , 2008, Annals of the New York Academy of Sciences.

[181]  I. Bechmann,et al.  TREM2 is upregulated in amyloid plaque‐associated microglia in aged APP23 transgenic mice , 2008, Glia.

[182]  Kostas Vekrellis,et al.  Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and Macroautophagy in Neuronal Cells* , 2008, Journal of Biological Chemistry.

[183]  E. Masliah,et al.  The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. , 2008, The Journal of clinical investigation.

[184]  M. van Buchem,et al.  Correlation of magnetization transfer ratio histogram parameters with neuropsychiatric systemic lupus erythematosus criteria and proton magnetic resonance spectroscopy: association of magnetization transfer ratio peak height with neuronal and cognitive dysfunction. , 2008, Arthritis and rheumatism.

[185]  S. Muller,et al.  Apoptosis-linked changes in the phosphorylation status and subcellular localization of the spliceosomal autoantigen U1-70K , 2008, Cell Death and Differentiation.

[186]  Xun Hu,et al.  TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis , 2008, Science.

[187]  B. Volpe,et al.  Neuropsychiatric systemic lupus erythematosus reconsidered , 2008, Nature Clinical Practice Rheumatology.

[188]  G. Roussel,et al.  Route of Uptake of Palmitoylated Encephalitogenic Peptides of Myelin Proteolipid Protein by Antigen-Presenting Cells: Importance of the Type of Bond between Lipid Chain and Peptide and Relevance to Autoimmunity1 , 2008, The Journal of Immunology.

[189]  V. Parietti,et al.  Importance of spliceosomal RNP1 motif for intermolecular T-B cell spreading and tolerance restoration in lupus , 2007, Arthritis research & therapy.

[190]  S. Schreiber,et al.  Small molecules enhance autophagy and reduce toxicity in Huntington's disease models. , 2007, Nature chemical biology.

[191]  M. Mattson,et al.  Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease , 2007, Neurobiology of Disease.

[192]  Pablo A. Rio,et al.  Voxel-based morphometry of brain SPECT can detect the presence of active central nervous system involvement in systemic lupus erythematosus. , 2007, Rheumatology.

[193]  D. Rubinsztein,et al.  Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein* , 2007, Journal of Biological Chemistry.

[194]  Andis Klegeris,et al.  Alpha‐synuclein and its disease‐causing mutants induce ICAM‐1 and IL‐6 in human astrocytes and astrocytoma cells , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[195]  Susan Lindquist,et al.  Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models. , 2006, Human molecular genetics.

[196]  Hideyuki Okano,et al.  Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice , 2006, Nature.

[197]  L. Raymond,et al.  Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin , 2006, Cell.

[198]  Alexei Degterev,et al.  Regulation of Intracellular Accumulation of Mutant Huntingtin by Beclin 1* , 2006, Journal of Biological Chemistry.

[199]  R. Hughes,et al.  Pathogenesis of chronic inflammatory demyelinating polyradiculoneuropathy , 2006, Journal of the peripheral nervous system : JPNS.

[200]  F. Cendes,et al.  Hippocampal atrophy in systemic lupus erythematosus , 2006, Annals of the rheumatic diseases.

[201]  G. Stoll,et al.  Macrophage clustering as a diagnostic marker in sural nerve biopsies of patients with CIDP , 2005, Neurology.

[202]  S. Muller,et al.  Selective Modulation of CD4+ T Cells from Lupus Patients by a Promiscuous, Protective Peptide Analog1 , 2005, The Journal of Immunology.

[203]  L. Tjernberg,et al.  Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease , 2005, The Journal of cell biology.

[204]  Li Min Li,et al.  Cerebral and corpus callosum atrophy in systemic lupus erythematosus. , 2005, Arthritis and rheumatism.

[205]  A. Kaasik,et al.  Up‐regulation of lysosomal cathepsin L and autophagy during neuronal death induced by reduced serum and potassium , 2005, The European journal of neuroscience.

[206]  Andrew B West,et al.  Molecular pathophysiology of Parkinson's disease. , 2005, Annual review of neuroscience.

[207]  R. Hughes,et al.  Antibodies to peripheral nerve myelin proteins in chronic inflammatory demyelinating polyradiculoneuropathy , 2005 .

[208]  R. Xavier,et al.  Neuropsychiatric systemic lupus erythematosus: correlation of brain MR imaging, CT, and SPECT. , 2005, Clinical imaging.

[209]  Delu Zhou,et al.  Lamp-2a facilitates MHC class II presentation of cytoplasmic antigens. , 2005, Immunity.

[210]  S. Humbert,et al.  Axonal transport failure in neurodegenerative disorders: the case of Huntington's disease. , 2005, Pathologie-biologie.

[211]  M. Dalakas,et al.  Gene expression profiling in chronic inflammatory demyelinating polyneuropathy , 2005, Journal of Neuroimmunology.

[212]  Ralph A. Nixon,et al.  Extensive Involvement of Autophagy in Alzheimer Disease: An Immuno-Electron Microscopy Study , 2005, Journal of neuropathology and experimental neurology.

[213]  Richard E. Carson,et al.  Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[214]  V. Parietti,et al.  Intramolecular T cell spreading in unprimed MRL/lpr mice: importance of the U1-70k protein sequence 131-151. , 2004, Arthritis and rheumatism.

[215]  Peter T. Lansbury,et al.  Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy , 2004, Science.

[216]  H. Hartung,et al.  Advances in understanding and treatment of immune‐mediated disorders of the peripheral nervous system , 2004, Muscle & nerve.

[217]  S. Humbert,et al.  Huntington's disease: how does huntingtin, an anti-apoptotic protein, become toxic? , 2004, Pathologie-biologie.

[218]  R. Nussbaum,et al.  Hereditary Early-Onset Parkinson's Disease Caused by Mutations in PINK1 , 2004, Science.

[219]  Francesco Scaravilli,et al.  Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease , 2004, Nature Genetics.

[220]  A. Morton,et al.  Regional and progressive changes in brain expression of complexin II in a mouse transgenic for the Huntington’s Disease mutation , 2004, Brain Research Bulletin.

[221]  S. Emr,et al.  A unified nomenclature for yeast autophagy-related genes. , 2003, Developmental cell.

[222]  Jeremy N. Skepper,et al.  α-Synuclein Is Degraded by Both Autophagy and the Proteasome* , 2003, Journal of Biological Chemistry.

[223]  B. Fernandez,et al.  Predictive, pre‐natal and diagnostic genetic testing for Huntington's disease: the experience in Canada from 1987 to 2000 , 2003, Clinical genetics.

[224]  M. Patarroyo,et al.  T cell recognition and therapeutic effect of a phosphorylated synthetic peptide of the 70K snRNP protein administered in MRL/lpr mice , 2003 .

[225]  C. Savage,et al.  γδ T cells infiltrating sensory nerve biopsies from patients with inflammatory neuropathy , 2002, Journal of Neurology.

[226]  J. Rothstein,et al.  From charcot to lou gehrig: deciphering selective motor neuron death in als , 2001, Nature Reviews Neuroscience.

[227]  R. Sobel,et al.  Thiopalmitoylation of Myelin Proteolipid Protein Epitopes Enhances Immunogenicity and Encephalitogenicity1 , 2001, The Journal of Immunology.

[228]  M. Mori,et al.  Serum levels of tumor necrosis factor–α in chronic inflammatory demyelinating polyneuropathy , 2001, Neurology.

[229]  K. Petry,et al.  Chronic inflammatory demyelinating polyneuropathy: immunopathological and ultrastructural study of peripheral nerve biopsy in 42 cases. , 2000, Ultrastructural pathology.

[230]  J. Pollard,et al.  Passive transfer of demyelination by serum or IgG from chronic inflammatory demyelinating polyneuropathy patients , 2000, Annals of neurology.

[231]  René Hen,et al.  Reversal of Neuropathology and Motor Dysfunction in a Conditional Model of Huntington's Disease , 2000, Cell.

[232]  H. Hibshoosh,et al.  Induction of autophagy and inhibition of tumorigenesis by beclin 1 , 1999, Nature.

[233]  K. Takabayashi,et al.  Decreased Regional Cerebral Metabolic Rate for Glucose in Systemic Lupus erythematosus Patients with Psychiatric Symptoms , 1999, European Neurology.

[234]  Caroline Gordon,et al.  The American College of Rheumatology nomenclature and case definitions for neuropsychiatric lupus syndromes. , 1999, Arthritis and rheumatism.

[235]  F. Chédru,et al.  Clinicopathologic findings and prognosis of chronic inflammatory demyelinating polyneuropathy , 1999, Neurology.

[236]  D. Tagle,et al.  Mutant Huntingtin Expression in Clonal Striatal Cells: Dissociation of Inclusion Formation and Neuronal Survival by Caspase Inhibition , 1999, The Journal of Neuroscience.

[237]  S. Minoshima,et al.  Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism , 1998, Nature.

[238]  J. Penney,et al.  Huntingtin localization in brains of normal and Huntington's disease patients , 1997, Annals of neurology.

[239]  D. Borchelt,et al.  ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing Inclusions , 1997, Neuron.

[240]  P S Harper,et al.  Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats. , 1996, American journal of human genetics.

[241]  H. Hartung,et al.  Inflammatory infiltrates in sural nerve biopsies in Guillain‐Barré syndrome and chronic inflammatory demyelinating neuropathy , 1996, Muscle & nerve.

[242]  L. Forno,et al.  Neuropathology of Parkinson's Disease , 1996, Journal of neuropathology and experimental neurology.

[243]  G. Schellenberg,et al.  Candidate gene for the chromosome 1 familial Alzheimer's disease locus , 1995, Science.

[244]  M. Hayden,et al.  Sex-dependent mechanisms for expansions and contractions of the CAG repeat on affected Huntington disease chromosomes. , 1995, American journal of human genetics.

[245]  D. Pollen,et al.  Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease , 1995, Nature.

[246]  H. Hartung,et al.  Serum interleukin‐2 concentrations in Guillain‐Barré syndrome and chronic idiopathic demyelinating polyradiculoneuropathy: Comparison with other neurological diseases of presumed immunopathogenesis , 1991, Annals of neurology.

[247]  M. Pericak-Vance,et al.  Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease , 1991, Nature.

[248]  Joseph B. Martin Huntington's disease , 1984, Neurology.

[249]  A. Smith Clinical trials , 1984, The Medical journal of Australia.

[250]  W. Engel,et al.  Immunoglobulin and complement deposits in nerves of patients with chronic relapsing polyneuropathy. , 1980, Archives of neurology.

[251]  J. Dixon,et al.  “Phagocytic” Lysosomes in Chromatolytic Neurones , 1967, Nature.

[252]  D. Barwick,et al.  Multiple Sclerosis: Therapeutic Trials of Chloroquine, Soluble Aspirin, and Gammaglobulin , 1963, British medical journal.

[253]  M. D’Amelio,et al.  Role of Autophagy in Brain Sculpture: Physiological and Pathological Implications , 2016 .

[254]  Eric H Kim,et al.  The Neuropathology of Huntington's Disease. , 2015, Current topics in behavioral neurosciences.

[255]  S. Baldovino,et al.  Central nervous system involvement in systemic lupus erythematosus: Overview on classification criteria. , 2013, Autoimmunity reviews.

[256]  J. Kere,et al.  Replication of GWAS-identified systemic lupus erythematosus susceptibility genes affirms B-cell receptor pathway signalling and strengthens the role of IRF5 in disease susceptibility in a Northern European population. , 2012, Rheumatology.

[257]  B. Šakić The MRL model: an invaluable tool in studies of autoimmunity-brain interactions. , 2012, Methods in molecular biology.

[258]  N. Abbott,et al.  Effect of trehalose on the interaction of Alzheimer's Aβ-peptide and anionic lipid monolayers. , 2011, Biochimica et biophysica acta.

[259]  S. Muller,et al.  Spliceosomal Peptide P 140 for Immunotherapy of Systemic Lupus Erythematosus Results of an Early Phase II Clinical Trial , 2008 .

[260]  M. Pypaert,et al.  Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes. , 2007, Immunity.

[261]  Robin L Brey,et al.  Neuropsychiatric lupus: clinical and imaging aspects. , 2007, Bulletin of the NYU hospital for joint diseases.

[262]  M. Mattson,et al.  Energy intake and amyotrophic lateral sclerosis , 2007, NeuroMolecular Medicine.

[263]  F. Marshall,et al.  Behavioral symptoms associated with Huntington's disease. , 2005, Advances in neurology.

[264]  S. Muller,et al.  Selective Modulation of CD 4 T Cells from Lupus Patients by a Promiscuous , Protective Peptide Analog 1 , 2005 .

[265]  Leonidas Stefanis,et al.  Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. , 2004, Science.

[266]  P. Jenner,et al.  Oxidative stress in Parkinson's disease , 2003, Annals of neurology.

[267]  M. Patarroyo,et al.  T cell recognition and therapeutic effect of a phosphorylated synthetic peptide of the 70K snRNP protein administered in MR/lpr mice. , 2003, European journal of immunology.

[268]  M. Mori,et al.  Serum levels of tumor necrosis factor-alpha in chronic inflammatory demyelinating polyneuropathy. , 2001, Neurology.

[269]  Y. Agid,et al.  Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease. , 1997, Histology and histopathology.

[270]  C. Harding,et al.  Pathways of antigen processing. , 1991, Current opinion in immunology.

[271]  S. Stellar,et al.  Electron microscope and enzyme studies in cerebral biopsies of Huntington's chorea. , 1974, Transactions of the American Neurological Association.

[272]  T. Takahashi [Erythematosus]. , 1971, Nihon rinsho. Japanese journal of clinical medicine.

[273]  M. Pericak-Vance,et al.  Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis , 2009, Science.