Autophagy in neuroinflammatory diseases.
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[1] P. Boya,et al. Lysosomal cell death mechanisms in aging , 2016, Ageing Research Reviews.
[2] C. Selmi,et al. Current trends in autoimmunity and the nervous system. , 2016, Journal of autoimmunity.
[3] L. Shulman,et al. Clinical subtypes and genetic heterogeneity: of lumping and splitting in Parkinson disease. , 2016, Current opinion in neurology.
[4] G. Bu,et al. TREMs in Alzheimer's disease: Genetic and clinical investigations. , 2016, Clinica chimica acta; international journal of clinical chemistry.
[5] A. Ittner. SITE-SPECIFIC PHOSPHORYLATION OF TAU INHIBITS AMYLOID-β TOXICITY IN ALZHEIMER’S MICE , 2016, Alzheimer's & Dementia.
[6] S. Muller,et al. Autoimmunity, neuroinflammation, pathogen load: A decisive crosstalk in neuropsychiatric SLE. , 2016, Journal of autoimmunity.
[7] M. Govoni,et al. The diagnosis and clinical management of the neuropsychiatric manifestations of lupus. , 2016, Journal of autoimmunity.
[8] M. Petri,et al. Immunomodulators in SLE: Clinical evidence and immunologic actions. , 2016, Journal of autoimmunity.
[9] R. Barker,et al. Neuroendocrine abnormalities in Parkinson's disease , 2016, Journal of Neurology, Neurosurgery & Psychiatry.
[10] Tao Wu,et al. The study of brain functional connectivity in Parkinson’s disease , 2016, Translational Neurodegeneration.
[11] K. Bourzac. Diagnosis: Warning signs , 2016, Nature.
[12] K. Chand,et al. Recent progress in repositioning Alzheimer's disease drugs based on a multitarget strategy. , 2016, Future medicinal chemistry.
[13] D. B. Vieira,et al. Getting into the brain: liposome-based strategies for effective drug delivery across the blood–brain barrier , 2016, International journal of nanomedicine.
[14] K. Cadwell. Crosstalk between autophagy and inflammatory signalling pathways: balancing defence and homeostasis , 2016, Nature Reviews Immunology.
[15] H. Ryu,et al. Astrocytes and Microglia as Non-cell Autonomous Players in the Pathogenesis of ALS , 2016, Experimental Neurobiology.
[16] C. Putterman,et al. The role of B cells and autoantibodies in neuropsychiatric lupus. , 2016, Autoimmunity reviews.
[17] C. Hartmann,et al. Deep Brain Stimulation in Huntington’s Disease—Preliminary Evidence on Pathophysiology, Efficacy and Safety , 2016, Brain sciences.
[18] M. Xilouri,et al. Impairment of chaperone-mediated autophagy induces dopaminergic neurodegeneration in rats , 2016, Autophagy.
[19] M. Vila,et al. The Parkinson Disease Mitochondrial Hypothesis , 2016, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.
[20] H. Adachi,et al. Natural Compounds Preventing Neurodegenerative Diseases Through Autophagic Activation. , 2016, Journal of UOEH.
[21] Mandar S Jog,et al. An update on the diagnosis and treatment of Parkinson disease , 2016, Canadian Medical Association Journal.
[22] J. Brotchie,et al. Treatment with Trehalose Prevents Behavioral and Neurochemical Deficits Produced in an AAV α-Synuclein Rat Model of Parkinson’s Disease , 2016, Molecular Neurobiology.
[23] Andrew B Singleton,et al. Genetics in Parkinson disease: Mendelian versus non‐Mendelian inheritance , 2016, Journal of neurochemistry.
[24] Wenting Zhu,et al. Autophagy is involved in the pathogenesis of experimental autoimmune neuritis in rats , 2016, Neuroreport.
[25] F. Mahn,et al. Resveratrol reduces amyloid-beta (Aβ1–42)-induced paralysis through targeting proteostasis in an Alzheimer model of Caenorhabditis elegans , 2016, European Journal of Nutrition.
[26] Melvyn W B Zhang,et al. A meta-analysis of serum and cerebrospinal fluid autoantibodies in neuropsychiatric systemic lupus erythematosus. , 2016, Autoimmunity reviews.
[27] Harald Sontheimer,et al. Glia as drivers of abnormal neuronal activity , 2015, Nature Neuroscience.
[28] D. Troost,et al. NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients , 2015, Glia.
[29] J. Blum,et al. A central role for HSC70 in regulating antigen trafficking and MHC class II presentation. , 2015, Molecular immunology.
[30] Zhen Zhao,et al. Establishment and Dysfunction of the Blood-Brain Barrier , 2015, Cell.
[31] L. Citterio,et al. TRPC6 gene variants and neuropsychiatric lupus , 2015, Journal of Neuroimmunology.
[32] K. Myhr,et al. Disease-modifying treatments for multiple sclerosis – a review of approved medications , 2015, European journal of neurology.
[33] Zhigui Li,et al. Triptolide Inhibited Cytotoxicity of Differentiated PC12 Cells Induced by Amyloid-Beta25–35 via the Autophagy Pathway , 2015, PloS one.
[34] Jill A Hollenbach,et al. The immunogenetics of multiple sclerosis: A comprehensive review. , 2015, Journal of autoimmunity.
[35] H. Reichmann,et al. Pathogenesis of Parkinson disease—the gut–brain axis and environmental factors , 2015, Nature Reviews Neurology.
[36] Ji Eun Lee,et al. Role of autophagy in the pathogenesis of amyotrophic lateral sclerosis. , 2015, Biochimica et biophysica acta.
[37] J. Atkin,et al. Golgi fragmentation in amyotrophic lateral sclerosis, an overview of possible triggers and consequences , 2015, Front. Neurosci..
[38] F. Rizzi,et al. EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism , 2015, Scientific Reports.
[39] Steffen Jung,et al. Microglia Plasticity During Health and Disease: An Immunological Perspective. , 2015, Trends in immunology.
[40] J. Harper,et al. The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy. , 2015, Molecular cell.
[41] I. Blair,et al. ALS-associated mutant FUS inhibits macroautophagy which is restored by overexpression of Rab1 , 2015, Cell Death Discovery.
[42] R. Nixon,et al. Presenilin 1 Maintains Lysosomal Ca(2+) Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification. , 2015, Cell reports.
[43] C. Mclean,et al. Rab1-dependent ER–Golgi transport dysfunction is a common pathogenic mechanism in SOD1, TDP-43 and FUS-associated ALS , 2015, Acta Neuropathologica.
[44] J. Burman,et al. The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy , 2015, Nature.
[45] E. Masliah,et al. Autophagy in Alzheimer’s disease , 2015, Reviews in the neurosciences.
[46] Shihua Li,et al. Therapeutic Effect of Berberine on Huntington’s Disease Transgenic Mouse Model , 2015, PloS one.
[47] Y. Li,et al. Trehalose decreases mutant SOD1 expression and alleviates motor deficiency in early but not end-stage amyotrophic lateral sclerosis in a SOD1-G93A mouse model , 2015, Neuroscience.
[48] D. Rubinsztein,et al. Therapeutic targeting of autophagy in neurodegenerative and infectious diseases , 2015, The Journal of experimental medicine.
[49] Y. Lo,et al. FRI0412 Symptoms of Attention Deficit Hyperactivity Disorder in Patients with Systemic Lupus Erythematosus , 2015 .
[50] J. Mintern,et al. Modulation of antigen presentation by intracellular trafficking. , 2015, Current opinion in immunology.
[51] Angeleen Fleming,et al. Compromised autophagy and neurodegenerative diseases , 2015, Nature Reviews Neuroscience.
[52] S. Muller,et al. Manipulating Autophagic Processes in Autoimmune Diseases: A Special Focus on Modulating Chaperone-Mediated Autophagy, an Emerging Therapeutic Target , 2015, Front. Immunol..
[53] H. Houlden,et al. Exome sequencing uncovers hidden pathways in familial and sporadic ALS , 2015, Nature Neuroscience.
[54] Junying Yuan,et al. Autophagy in Neurodegenerative Diseases: From Mechanism to Therapeutic Approach , 2015, Molecules and cells.
[55] Ju-Hee Lee,et al. EGCG-mediated autophagy flux has a neuroprotection effect via a class III histone deacetylase in primary neuron cells , 2015, Oncotarget.
[56] Paulo Pereira,et al. Autophagy and ubiquitination in cardiovascular diseases. , 2015, DNA and cell biology.
[57] O. Garaschuk,et al. Neuroinflammation in Alzheimer's disease , 2015, The Lancet Neurology.
[58] A. Echaniz-Laguna,et al. A metabolic switch toward lipid use in glycolytic muscle is an early pathologic event in a mouse model of amyotrophic lateral sclerosis , 2015, EMBO molecular medicine.
[59] S. Muller,et al. Resetting the autoreactive immune system with a therapeutic peptide in lupus , 2015, Lupus.
[60] J. Chapman,et al. Neuropsychiatric lupus: a mosaic of clinical presentations , 2015, BMC Medicine.
[61] Yong Tae Kwon,et al. Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies , 2015, Experimental & Molecular Medicine.
[62] A. Cuervo,et al. Modulation of deregulated chaperone-mediated autophagy by a phosphopeptide , 2015, Autophagy.
[63] M. Hayden,et al. Autophagy in Huntington disease and huntingtin in autophagy , 2015, Trends in Neurosciences.
[64] L. Kremer,et al. Characterization of a new rat model for chronic inflammatory demyelinating polyneuropathies , 2015, Journal of Neuroimmunology.
[65] P. Codogno,et al. Development of autophagy inducers in clinical medicine. , 2015, The Journal of clinical investigation.
[66] S. Cenci. Autophagy, a new determinant of plasma cell differentiation and antibody responses. , 2014, Molecular immunology.
[67] Y. Nakagawa,et al. Role of Microglial M1/M2 Polarization in Relapse and Remission of Psychiatric Disorders and Diseases , 2014, Pharmaceuticals.
[68] C. Hetz,et al. Targeting autophagy in neurodegenerative diseases. , 2014, Trends in pharmacological sciences.
[69] Haijian Wu,et al. Crosstalk Between Macroautophagy and Chaperone-Mediated Autophagy: Implications for the Treatment of Neurological Diseases , 2014, Molecular Neurobiology.
[70] Y. Li,et al. Downregulation of PI3K/Akt/mTOR signaling pathway in curcumin-induced autophagy in APP/PS1 double transgenic mice. , 2014, European journal of pharmacology.
[71] S. Muller,et al. Pharmacological regulators of autophagy and their link with modulators of lupus disease , 2014, British journal of pharmacology.
[72] S. Muller,et al. Neuropsychiatric systemic lupus erythematosus: pathogenesis and biomarkers , 2014, Nature Reviews Neurology.
[73] N. Kowall,et al. Therapeutic targeting of epigenetic components in amyotrophic lateral sclerosis (ALS). , 2014, Current medicinal chemistry.
[74] R. Pacheco,et al. Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases , 2014, Journal of Neuroimmunology.
[75] A. Cuervo,et al. Chaperone mediated autophagy regulates T cell responses through targeted degradation of negative regulators of T cell activation , 2014, Nature Immunology.
[76] S. Muller,et al. Neuropsychiatric systemic lupus erythematosus and cognitive dysfunction: the MRL-lpr mouse strain as a model. , 2014, Autoimmunity reviews.
[77] N. Eissa,et al. Deficiency of Autophagy in Dendritic Cells Protects against Experimental Autoimmune Encephalomyelitis* , 2014, The Journal of Biological Chemistry.
[78] H. Weiner,et al. Differential roles of microglia and monocytes in the inflamed central nervous system , 2014, The Journal of experimental medicine.
[79] J. Lou,et al. Hypercaloric enteral nutrition in patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled phase 2 trial , 2014, The Lancet.
[80] S. Finkbeiner,et al. Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models , 2014, Nature chemical biology.
[81] J. Hanly. Diagnosis and management of neuropsychiatric SLE , 2014, Nature Reviews Rheumatology.
[82] G. Kroemer,et al. Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis , 2014, Autophagy.
[83] A. Laties,et al. Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer’s disease-linked presenilin 1 A246E mutation can be reversed with cAMP , 2014, Neuroscience.
[84] M. Mena,et al. Trehalose Reverses Cell Malfunction in Fibroblasts from Normal and Huntington's Disease Patients Caused by Proteosome Inhibition , 2014, PloS one.
[85] S. Muller,et al. The importance of implementing proper selection of excipients in lupus clinical trials , 2014, Lupus.
[86] P. Gleeson,et al. C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking , 2014, Human molecular genetics.
[87] T. Vyse,et al. Autophagy is activated in systemic lupus erythematosus and required for plasmablast development , 2014, Annals of the rheumatic diseases.
[88] P. Szewczyk,et al. In vivo evaluation of brain damage in the course of systemic lupus erythematosus using magnetic resonance spectroscopy, perfusion-weighted and diffusion-tensor imaging , 2014, Lupus.
[89] Shang-Der Chen,et al. Resveratrol Partially Prevents Rotenone-Induced Neurotoxicity in Dopaminergic SH-SY5Y Cells through Induction of Heme Oxygenase-1 Dependent Autophagy , 2014, International journal of molecular sciences.
[90] S. Cessie,et al. Mortality in neuropsychiatric systemic lupus erythematosus (NPSLE) , 2014, Lupus.
[91] N. Mizushima,et al. Autophagy and human diseases , 2013, Cell Research.
[92] S. Snyder,et al. Rhes, a Striatal-selective Protein Implicated in Huntington Disease, Binds Beclin-1 and Activates Autophagy* , 2013, The Journal of Biological Chemistry.
[93] J. Ule,et al. Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic , 2013, Cell reports.
[94] A. Cuervo,et al. Chaperone-mediated autophagy: roles in disease and aging , 2013, Cell Research.
[95] H. Wood. Neurodegenerative disease: C9orf72 RNA foci—a therapeutic target for ALS and FTD? , 2013, Nature Reviews Neurology.
[96] Liang Liu,et al. Onjisaponin B Derived from Radix Polygalae Enhances Autophagy and Accelerates the Degradation of Mutant α-Synuclein and Huntingtin in PC-12 Cells , 2013, International journal of molecular sciences.
[97] F. Stricher,et al. HSPA8/HSC70 chaperone protein , 2013, Autophagy.
[98] M. Xilouri,et al. LAMP2A as a therapeutic target in Parkinson disease , 2013, Autophagy.
[99] Núria Bargalló,et al. Neuropsychiatric systemic lupus erythematosus: magnetic resonance imaging findings and correlation with clinical and immunological features. , 2013, Autoimmunity reviews.
[100] S. Sarkar,et al. Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers. , 2013, Biochemical Society transactions.
[101] Shizuo Akira,et al. Autophagy in infection, inflammation and immunity , 2013, Nature Reviews Immunology.
[102] P. Sachdev,et al. Alpha-Synuclein Transmission and Mitochondrial Toxicity in Primary Human Foetal Enteric Neurons In Vitro , 2013, Neurotoxicity Research.
[103] Z. Tao,et al. Epigallocatechin-gallate (EGCG) regulates autophagy in human retinal pigment epithelial cells: a potential role for reducing UVB light-induced retinal damage. , 2013, Biochemical and biophysical research communications.
[104] D. Boumpas,et al. Pathogenesis and treatment of CNS lupus , 2013, Current opinion in rheumatology.
[105] Hualiang Jiang,et al. Arctigenin Effectively Ameliorates Memory Impairment in Alzheimer's Disease Model Mice Targeting Both β-Amyloid Production and Clearance , 2013, The Journal of Neuroscience.
[106] D. Cleveland,et al. Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis , 2013, Neuron.
[107] F. Middleton,et al. HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE , 2013, Annals of the rheumatic diseases.
[108] V. Parpura,et al. Epigallocatechin Gallate (EGCG) Stimulates Autophagy in Vascular Endothelial Cells , 2013, The Journal of Biological Chemistry.
[109] Christine E. Becker,et al. CD36 coordinates NLRP3 inflammasome activation by facilitating the intracellular nucleation from soluble to particulate ligands in sterile inflammation , 2013, Nature Immunology.
[110] C. Hetz,et al. Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons , 2013, Autophagy.
[111] Sooyeon Lee,et al. Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification , 2013, The European journal of neuroscience.
[112] Keith A. Johnson,et al. CD33 Alzheimer’s disease locus: Altered monocyte function and amyloid biology , 2013, Nature Neuroscience.
[113] Bradley T. Hyman,et al. Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta , 2013, Neuron.
[114] Peter Cresswell,et al. Pathways of antigen processing. , 2013, Annual review of immunology.
[115] Wim Robberecht,et al. The changing scene of amyotrophic lateral sclerosis , 2013, Nature Reviews Neuroscience.
[116] A. Singleton,et al. TREM2 variants in Alzheimer's disease. , 2013, The New England journal of medicine.
[117] A. McKee,et al. Expression of Taurine Transporter (TauT) is Modulated by Heat Shock Factor 1 (HSF1) in Motor Neurons of ALS , 2012, Molecular Neurobiology.
[118] J. Gómez-Reino,et al. Lupuzor/P140 peptide in patients with systemic lupus erythematosus: a randomised, double-blind, placebo-controlled phase IIb clinical trial , 2012, Annals of the rheumatic diseases.
[119] E. Mandelkow,et al. Autophagic degradation of tau in primary neurons and its enhancement by trehalose , 2012, Neurobiology of Aging.
[120] S. Muller,et al. Peptide-based approaches to treat lupus and other autoimmune diseases. , 2012, Journal of autoimmunity.
[121] S. Lee,et al. The efficacy of brain 18 F-fluorodeoxyglucose positron emission tomography in neuropsychiatric lupus patients with normal brain magnetic resonance imaging findings , 2012, Lupus.
[122] A. Perl,et al. T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[123] S. Hadano,et al. Dysregulation of the Autophagy-Endolysosomal System in Amyotrophic Lateral Sclerosis and Related Motor Neuron Diseases , 2012, Neurology research international.
[124] A. Björklund,et al. Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo , 2012, PloS one.
[125] R. Ho,et al. A prospective functional MRI study for executive function in patients with systemic lupus erythematosus without neuropsychiatric symptoms. , 2012, Seminars in arthritis and rheumatism.
[126] C. Putterman,et al. Autoantibodies in lupus: culprits or passive bystanders? , 2012, Autoimmunity reviews.
[127] A. Korganow,et al. Macroautophagy is deregulated in murine and human lupus T lymphocytes , 2012, Autophagy.
[128] D. Klionsky,et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) , 2012, Autophagy.
[129] W. Malorni,et al. Role of autophagy in immunity and autoimmunity, with a special focus on systemic lupus erythematosus , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[130] Robert Clarke,et al. Guidelines for the use and interpretation of assays for monitoring autophagy , 2012 .
[131] F. Cecconi,et al. Aβ Toxicity in Alzheimer's Disease , 2012, Molecular Neurobiology.
[132] F. Leeuwen,et al. The ubiquitin proteasome system in neurodegenerative diseases: Culprit, accomplice or victim? , 2012, Progress in Neurobiology.
[133] D. Rubinsztein,et al. Control of autophagy as a therapy for neurodegenerative disease , 2012, Nature Reviews Neurology.
[134] W. Le,et al. Autophagy dysregulation in amyotrophic lateral sclerosis , 2012, Journal of the Neurological Sciences.
[135] Han-Ming Shen,et al. Isorhynchophylline, a natural alkaloid, promotes the degradation of alpha-synuclein in neuronal cells via inducing autophagy , 2012, Autophagy.
[136] Masaaki Komatsu,et al. Autophagy: Renovation of Cells and Tissues , 2011, Cell.
[137] Minesh Kapadia,et al. Autoimmune and inflammatory mechanisms of CNS damage , 2011, Progress in Neurobiology.
[138] R. Faull,et al. Population-specific expression analysis (PSEA) reveals molecular changes in diseased brain , 2011, Nature Methods.
[139] David Heckerman,et al. A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD , 2011, Neuron.
[140] D. Geschwind,et al. Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS , 2011, Neuron.
[141] M. Prescott,et al. Microautophagy in mammalian cells: Revisiting a 40-year-old conundrum , 2011, Autophagy.
[142] M. Hashefi,et al. PET/CT imaging in systemic lupus erythematosus , 2011, Annals of the New York Academy of Sciences.
[143] P. Gaffney,et al. Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort , 2011, Genes and Immunity.
[144] Hong Zhang,et al. Genetic association of PRDM1-ATG5 intergenic region and autophagy with systemic lupus erythematosus in a Chinese population , 2011, Annals of the rheumatic diseases.
[145] S. Sasaki. Autophagy in Spinal Cord Motor Neurons in Sporadic Amyotrophic Lateral Sclerosis , 2011, Journal of neuropathology and experimental neurology.
[146] Sung-soo Kim,et al. Suppression of autophagy and activation of glycogen synthase kinase 3beta facilitate the aggregate formation of tau. , 2011, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.
[147] M. Mena,et al. The accumulation of neurotoxic proteins, induced by proteasome inhibition, is reverted by trehalose, an enhancer of autophagy, in human neuroblastoma cells , 2011, Neurochemistry International.
[148] Annette Lee,et al. Risk Alleles for Systemic Lupus Erythematosus in a Large Case-Control Collection and Associations with Clinical Subphenotypes , 2011, PLoS genetics.
[149] Sudarshan C. Upadhya,et al. Role of ubiquitin-proteasome-mediated proteolysis in nervous system disease. , 2011, Biochimica et biophysica acta.
[150] A. Ludolph,et al. Energy metabolism in amyotrophic lateral sclerosis , 2011, The Lancet Neurology.
[151] C. Ross,et al. Huntington's disease: from molecular pathogenesis to clinical treatment , 2011, The Lancet Neurology.
[152] A. Caccamo,et al. Naturally Secreted Amyloid-β Increases Mammalian Target of Rapamycin (mTOR) Activity via a PRAS40-mediated Mechanism* , 2011, The Journal of Biological Chemistry.
[153] C. Oliveira,et al. Mitochondrial Dysfunction: The Road to Alpha-Synuclein Oligomerization in PD , 2011, Parkinson's disease.
[154] Jeroen van der Grond,et al. Tract-based spatial statistics on diffusion tensor imaging in systemic lupus erythematosus reveals localized involvement of white matter tracts. , 2010, Arthritis and rheumatism.
[155] Jin Zhou,et al. Distribution of Th17 cells and Th1 cells in peripheral blood and cerebrospinal fluid in chronic inflammatory demyelinating polyradiculoneuropathy , 2010, Journal of the peripheral nervous system : JPNS.
[156] Steven Finkbeiner,et al. A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model , 2010, Proceedings of the National Academy of Sciences.
[157] A. Cuervo,et al. Identification of regulators of chaperone-mediated autophagy. , 2010, Molecular cell.
[158] J. Ioannidis,et al. EULAR recommendations for the management of systemic lupus erythematosus with neuropsychiatric manifestations: report of a task force of the EULAR standing committee for clinical affairs , 2010, Annals of the rheumatic diseases.
[159] W. Beaino,et al. Thiopalmitoylated peptides from the peripheral nervous system myelin p0 protein: synthesis, characterization, and neuritogenic properties. , 2010, Bioconjugate chemistry.
[160] L. Tong,et al. Age at onset in Huntington’s disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7 , 2010, Human Genetics.
[161] G. Landreth,et al. The role of microglia in amyloid clearance from the AD brain , 2010, Journal of Neural Transmission.
[162] D. Boumpas,et al. Pathogenesis, diagnosis and management of neuropsychiatric SLE manifestations , 2010, Nature Reviews Rheumatology.
[163] C. Sommer,et al. Chronic inflammatory demyelinating polyradiculoneuropathy: diagnostic and therapeutic challenges for a treatable condition , 2010, The Lancet Neurology.
[164] D. Rubinsztein,et al. Chemical Inducers of Autophagy That Enhance the Clearance of Mutant Proteins in Neurodegenerative Diseases , 2010, The Journal of Biological Chemistry.
[165] G. Papadimitriou,et al. The neuropsychiatry of multiple sclerosis: Focus on disorders of mood, affect and behaviour , 2010, International review of psychiatry.
[166] K. Moore,et al. CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer , 2009, Nature Immunology.
[167] D. Cleveland,et al. Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond , 2009, The Journal of cell biology.
[168] M. Ferrari,et al. TREX1 gene variant in neuropsychiatric systemic lupus erythematosus , 2009, Annals of the rheumatic diseases.
[169] E. Masliah,et al. Beclin 1 Gene Transfer Activates Autophagy and Ameliorates the Neurodegenerative Pathology in α-Synuclein Models of Parkinson's and Lewy Body Diseases , 2009, The Journal of Neuroscience.
[170] B. Ganetzky,et al. Autophagy promotes synapse development in Drosophila , 2009, The Journal of cell biology.
[171] P. Carvey,et al. The blood–brain barrier in neurodegenerative disease: a rhetorical perspective , 2009, Journal of neurochemistry.
[172] B. Volpe,et al. Losing your nerves? Maybe it's the antibodies , 2009, Nature Reviews Immunology.
[173] W. Seaman,et al. A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia , 2009, Journal of neurochemistry.
[174] C. Langefeld,et al. Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies , 2009, Nature Reviews Genetics.
[175] Alain Van Dorsselaer,et al. The Spliceosomal Phosphopeptide P140 Controls the Lupus Disease by Interacting with the HSC70 Protein and via a Mechanism Mediated by γδ T Cells , 2009, PloS one.
[176] V. Crotzer,et al. Autophagy and Its Role in MHC-Mediated Antigen Presentation1 , 2009, The Journal of Immunology.
[177] G. Robertson,et al. Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis , 2009, Autophagy.
[178] T. Tomoda,et al. Unc-51 Controls Active Zone Density and Protein Composition by Downregulating ERK Signaling , 2009, The Journal of Neuroscience.
[179] S. Muller,et al. Spliceosomal peptide P140 for immunotherapy of systemic lupus erythematosus: results of an early phase II clinical trial. , 2008, Arthritis and rheumatism.
[180] S. Przedborski,et al. Oxidative Stress in Parkinson's Disease , 2008, Annals of the New York Academy of Sciences.
[181] I. Bechmann,et al. TREM2 is upregulated in amyloid plaque‐associated microglia in aged APP23 transgenic mice , 2008, Glia.
[182] Kostas Vekrellis,et al. Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and Macroautophagy in Neuronal Cells* , 2008, Journal of Biological Chemistry.
[183] E. Masliah,et al. The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. , 2008, The Journal of clinical investigation.
[184] M. van Buchem,et al. Correlation of magnetization transfer ratio histogram parameters with neuropsychiatric systemic lupus erythematosus criteria and proton magnetic resonance spectroscopy: association of magnetization transfer ratio peak height with neuronal and cognitive dysfunction. , 2008, Arthritis and rheumatism.
[185] S. Muller,et al. Apoptosis-linked changes in the phosphorylation status and subcellular localization of the spliceosomal autoantigen U1-70K , 2008, Cell Death and Differentiation.
[186] Xun Hu,et al. TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis , 2008, Science.
[187] B. Volpe,et al. Neuropsychiatric systemic lupus erythematosus reconsidered , 2008, Nature Clinical Practice Rheumatology.
[188] G. Roussel,et al. Route of Uptake of Palmitoylated Encephalitogenic Peptides of Myelin Proteolipid Protein by Antigen-Presenting Cells: Importance of the Type of Bond between Lipid Chain and Peptide and Relevance to Autoimmunity1 , 2008, The Journal of Immunology.
[189] V. Parietti,et al. Importance of spliceosomal RNP1 motif for intermolecular T-B cell spreading and tolerance restoration in lupus , 2007, Arthritis research & therapy.
[190] S. Schreiber,et al. Small molecules enhance autophagy and reduce toxicity in Huntington's disease models. , 2007, Nature chemical biology.
[191] M. Mattson,et al. Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease , 2007, Neurobiology of Disease.
[192] Pablo A. Rio,et al. Voxel-based morphometry of brain SPECT can detect the presence of active central nervous system involvement in systemic lupus erythematosus. , 2007, Rheumatology.
[193] D. Rubinsztein,et al. Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein* , 2007, Journal of Biological Chemistry.
[194] Andis Klegeris,et al. Alpha‐synuclein and its disease‐causing mutants induce ICAM‐1 and IL‐6 in human astrocytes and astrocytoma cells , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[195] Susan Lindquist,et al. Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models. , 2006, Human molecular genetics.
[196] Hideyuki Okano,et al. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice , 2006, Nature.
[197] L. Raymond,et al. Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin , 2006, Cell.
[198] Alexei Degterev,et al. Regulation of Intracellular Accumulation of Mutant Huntingtin by Beclin 1* , 2006, Journal of Biological Chemistry.
[199] R. Hughes,et al. Pathogenesis of chronic inflammatory demyelinating polyradiculoneuropathy , 2006, Journal of the peripheral nervous system : JPNS.
[200] F. Cendes,et al. Hippocampal atrophy in systemic lupus erythematosus , 2006, Annals of the rheumatic diseases.
[201] G. Stoll,et al. Macrophage clustering as a diagnostic marker in sural nerve biopsies of patients with CIDP , 2005, Neurology.
[202] S. Muller,et al. Selective Modulation of CD4+ T Cells from Lupus Patients by a Promiscuous, Protective Peptide Analog1 , 2005, The Journal of Immunology.
[203] L. Tjernberg,et al. Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease , 2005, The Journal of cell biology.
[204] Li Min Li,et al. Cerebral and corpus callosum atrophy in systemic lupus erythematosus. , 2005, Arthritis and rheumatism.
[205] A. Kaasik,et al. Up‐regulation of lysosomal cathepsin L and autophagy during neuronal death induced by reduced serum and potassium , 2005, The European journal of neuroscience.
[206] Andrew B West,et al. Molecular pathophysiology of Parkinson's disease. , 2005, Annual review of neuroscience.
[207] R. Hughes,et al. Antibodies to peripheral nerve myelin proteins in chronic inflammatory demyelinating polyradiculoneuropathy , 2005 .
[208] R. Xavier,et al. Neuropsychiatric systemic lupus erythematosus: correlation of brain MR imaging, CT, and SPECT. , 2005, Clinical imaging.
[209] Delu Zhou,et al. Lamp-2a facilitates MHC class II presentation of cytoplasmic antigens. , 2005, Immunity.
[210] S. Humbert,et al. Axonal transport failure in neurodegenerative disorders: the case of Huntington's disease. , 2005, Pathologie-biologie.
[211] M. Dalakas,et al. Gene expression profiling in chronic inflammatory demyelinating polyneuropathy , 2005, Journal of Neuroimmunology.
[212] Ralph A. Nixon,et al. Extensive Involvement of Autophagy in Alzheimer Disease: An Immuno-Electron Microscopy Study , 2005, Journal of neuropathology and experimental neurology.
[213] Richard E. Carson,et al. Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[214] V. Parietti,et al. Intramolecular T cell spreading in unprimed MRL/lpr mice: importance of the U1-70k protein sequence 131-151. , 2004, Arthritis and rheumatism.
[215] Peter T. Lansbury,et al. Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy , 2004, Science.
[216] H. Hartung,et al. Advances in understanding and treatment of immune‐mediated disorders of the peripheral nervous system , 2004, Muscle & nerve.
[217] S. Humbert,et al. Huntington's disease: how does huntingtin, an anti-apoptotic protein, become toxic? , 2004, Pathologie-biologie.
[218] R. Nussbaum,et al. Hereditary Early-Onset Parkinson's Disease Caused by Mutations in PINK1 , 2004, Science.
[219] Francesco Scaravilli,et al. Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease , 2004, Nature Genetics.
[220] A. Morton,et al. Regional and progressive changes in brain expression of complexin II in a mouse transgenic for the Huntington’s Disease mutation , 2004, Brain Research Bulletin.
[221] S. Emr,et al. A unified nomenclature for yeast autophagy-related genes. , 2003, Developmental cell.
[222] Jeremy N. Skepper,et al. α-Synuclein Is Degraded by Both Autophagy and the Proteasome* , 2003, Journal of Biological Chemistry.
[223] B. Fernandez,et al. Predictive, pre‐natal and diagnostic genetic testing for Huntington's disease: the experience in Canada from 1987 to 2000 , 2003, Clinical genetics.
[224] M. Patarroyo,et al. T cell recognition and therapeutic effect of a phosphorylated synthetic peptide of the 70K snRNP protein administered in MRL/lpr mice , 2003 .
[225] C. Savage,et al. γδ T cells infiltrating sensory nerve biopsies from patients with inflammatory neuropathy , 2002, Journal of Neurology.
[226] J. Rothstein,et al. From charcot to lou gehrig: deciphering selective motor neuron death in als , 2001, Nature Reviews Neuroscience.
[227] R. Sobel,et al. Thiopalmitoylation of Myelin Proteolipid Protein Epitopes Enhances Immunogenicity and Encephalitogenicity1 , 2001, The Journal of Immunology.
[228] M. Mori,et al. Serum levels of tumor necrosis factor–α in chronic inflammatory demyelinating polyneuropathy , 2001, Neurology.
[229] K. Petry,et al. Chronic inflammatory demyelinating polyneuropathy: immunopathological and ultrastructural study of peripheral nerve biopsy in 42 cases. , 2000, Ultrastructural pathology.
[230] J. Pollard,et al. Passive transfer of demyelination by serum or IgG from chronic inflammatory demyelinating polyneuropathy patients , 2000, Annals of neurology.
[231] René Hen,et al. Reversal of Neuropathology and Motor Dysfunction in a Conditional Model of Huntington's Disease , 2000, Cell.
[232] H. Hibshoosh,et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1 , 1999, Nature.
[233] K. Takabayashi,et al. Decreased Regional Cerebral Metabolic Rate for Glucose in Systemic Lupus erythematosus Patients with Psychiatric Symptoms , 1999, European Neurology.
[234] Caroline Gordon,et al. The American College of Rheumatology nomenclature and case definitions for neuropsychiatric lupus syndromes. , 1999, Arthritis and rheumatism.
[235] F. Chédru,et al. Clinicopathologic findings and prognosis of chronic inflammatory demyelinating polyneuropathy , 1999, Neurology.
[236] D. Tagle,et al. Mutant Huntingtin Expression in Clonal Striatal Cells: Dissociation of Inclusion Formation and Neuronal Survival by Caspase Inhibition , 1999, The Journal of Neuroscience.
[237] S. Minoshima,et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism , 1998, Nature.
[238] J. Penney,et al. Huntingtin localization in brains of normal and Huntington's disease patients , 1997, Annals of neurology.
[239] D. Borchelt,et al. ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing Inclusions , 1997, Neuron.
[240] P S Harper,et al. Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats. , 1996, American journal of human genetics.
[241] H. Hartung,et al. Inflammatory infiltrates in sural nerve biopsies in Guillain‐Barré syndrome and chronic inflammatory demyelinating neuropathy , 1996, Muscle & nerve.
[242] L. Forno,et al. Neuropathology of Parkinson's Disease , 1996, Journal of neuropathology and experimental neurology.
[243] G. Schellenberg,et al. Candidate gene for the chromosome 1 familial Alzheimer's disease locus , 1995, Science.
[244] M. Hayden,et al. Sex-dependent mechanisms for expansions and contractions of the CAG repeat on affected Huntington disease chromosomes. , 1995, American journal of human genetics.
[245] D. Pollen,et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease , 1995, Nature.
[246] H. Hartung,et al. Serum interleukin‐2 concentrations in Guillain‐Barré syndrome and chronic idiopathic demyelinating polyradiculoneuropathy: Comparison with other neurological diseases of presumed immunopathogenesis , 1991, Annals of neurology.
[247] M. Pericak-Vance,et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease , 1991, Nature.
[248] Joseph B. Martin. Huntington's disease , 1984, Neurology.
[249] A. Smith. Clinical trials , 1984, The Medical journal of Australia.
[250] W. Engel,et al. Immunoglobulin and complement deposits in nerves of patients with chronic relapsing polyneuropathy. , 1980, Archives of neurology.
[251] J. Dixon,et al. “Phagocytic” Lysosomes in Chromatolytic Neurones , 1967, Nature.
[252] D. Barwick,et al. Multiple Sclerosis: Therapeutic Trials of Chloroquine, Soluble Aspirin, and Gammaglobulin , 1963, British medical journal.
[253] M. D’Amelio,et al. Role of Autophagy in Brain Sculpture: Physiological and Pathological Implications , 2016 .
[254] Eric H Kim,et al. The Neuropathology of Huntington's Disease. , 2015, Current topics in behavioral neurosciences.
[255] S. Baldovino,et al. Central nervous system involvement in systemic lupus erythematosus: Overview on classification criteria. , 2013, Autoimmunity reviews.
[256] J. Kere,et al. Replication of GWAS-identified systemic lupus erythematosus susceptibility genes affirms B-cell receptor pathway signalling and strengthens the role of IRF5 in disease susceptibility in a Northern European population. , 2012, Rheumatology.
[257] B. Šakić. The MRL model: an invaluable tool in studies of autoimmunity-brain interactions. , 2012, Methods in molecular biology.
[258] N. Abbott,et al. Effect of trehalose on the interaction of Alzheimer's Aβ-peptide and anionic lipid monolayers. , 2011, Biochimica et biophysica acta.
[259] S. Muller,et al. Spliceosomal Peptide P 140 for Immunotherapy of Systemic Lupus Erythematosus Results of an Early Phase II Clinical Trial , 2008 .
[260] M. Pypaert,et al. Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes. , 2007, Immunity.
[261] Robin L Brey,et al. Neuropsychiatric lupus: clinical and imaging aspects. , 2007, Bulletin of the NYU hospital for joint diseases.
[262] M. Mattson,et al. Energy intake and amyotrophic lateral sclerosis , 2007, NeuroMolecular Medicine.
[263] F. Marshall,et al. Behavioral symptoms associated with Huntington's disease. , 2005, Advances in neurology.
[264] S. Muller,et al. Selective Modulation of CD 4 T Cells from Lupus Patients by a Promiscuous , Protective Peptide Analog 1 , 2005 .
[265] Leonidas Stefanis,et al. Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. , 2004, Science.
[266] P. Jenner,et al. Oxidative stress in Parkinson's disease , 2003, Annals of neurology.
[267] M. Patarroyo,et al. T cell recognition and therapeutic effect of a phosphorylated synthetic peptide of the 70K snRNP protein administered in MR/lpr mice. , 2003, European journal of immunology.
[268] M. Mori,et al. Serum levels of tumor necrosis factor-alpha in chronic inflammatory demyelinating polyneuropathy. , 2001, Neurology.
[269] Y. Agid,et al. Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease. , 1997, Histology and histopathology.
[270] C. Harding,et al. Pathways of antigen processing. , 1991, Current opinion in immunology.
[271] S. Stellar,et al. Electron microscope and enzyme studies in cerebral biopsies of Huntington's chorea. , 1974, Transactions of the American Neurological Association.
[272] T. Takahashi. [Erythematosus]. , 1971, Nihon rinsho. Japanese journal of clinical medicine.
[273] M. Pericak-Vance,et al. Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis , 2009, Science.