Modulation of surface TNF expression by human leukaemic cells alters their sensitivity to exogenous TNF.

[1]  A. Newland,et al.  Circumvention of P‐glycoprotein‐mediated drug resistance in human leukaemic cells by non‐immunosuppressive cyclosporin D analogue, SDZ PSC 833 , 1995, British journal of haematology.

[2]  K. Alitalo,et al.  c‐Myc induces cellular susceptibility to the cytotoxic action of TNF‐alpha. , 1994, The EMBO journal.

[3]  A. Porter,et al.  Nuclear c-Myc plays an important role in the cytotoxicity of tumor necrosis factor alpha in tumor cells , 1994, Molecular and cellular biology.

[4]  Z. Darżynkiewicz,et al.  Flow cytometric detection of apoptosis: comparison of the assays of in situ DNA degradation and chromatin changes. , 1994, Cytometry.

[5]  R. Clarke,et al.  Resistance to TNF-alpha and adriamycin in the human breast cancer MCF-7 cell line: relationship to MDR1, MnSOD, and TNF gene expression. , 1994, Cancer research.

[6]  J. Shelhamer,et al.  Interferon-gamma induces the synthesis and activation of cytosolic phospholipase A2. , 1994, The Journal of clinical investigation.

[7]  W. Fiers,et al.  Cell membrane permeabilization and cellular collapse, followed by loss of dehydrogenase activity: early events in tumour necrosis factor-induced cytotoxicity. , 1993, Cytokine.

[8]  M. Jäättelä,et al.  Overexpression of major heat shock protein hsp70 inhibits tumor necrosis factor-induced activation of phospholipase A2. , 1993, Journal of immunology.

[9]  Y. Ben-Neriah,et al.  Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB , 1993, Nature.

[10]  H. Koeffler,et al.  Regulation of manganese superoxide dismutase and other antioxidant genes in normal and leukemic hematopoietic cells and their relationship to cytotoxicity by tumor necrosis factor. , 1993, Blood.

[11]  M. Macey,et al.  Induction of surface tumor necrosis factor (TNF) expression and possible facilitation of surface TNF release from human monocytic cells by granulocyte-macrophage colony-stimulating factor or gamma interferon in combination with 1,25-dihydroxyvitamin D3. , 1993, Experimental hematology.

[12]  W. Fiers,et al.  Sensitization of tumor cells to tumor necrosis factor action by the protein kinase inhibitor staurosporine. , 1993, Cancer research.

[13]  K. Takeuchi,et al.  Arachidonic acid-selective cytosolic phospholipase A2 is crucial in the cytotoxic action of tumor necrosis factor. , 1993, The Journal of biological chemistry.

[14]  A. Mire-Sluis,et al.  Protein kinase C-dependent phosphorylation is involved in resistance to tumour necrosis factor-alpha-induced cytotoxicity in a human monocytoid cell line. , 1993, The Biochemical journal.

[15]  T. Tursz,et al.  The development of human tumor‐cell resistance to TNF‐α does not confer resistance to cytokine‐induced cellular cytotoxic mechanisms , 1992, International journal of cancer.

[16]  J. Safrit,et al.  Sensitivity of resistant human tumor cell lines to tumor necrosis factor and adriamycin used in combination: correlation between down-regulation of tumor necrosis factor-messenger RNA induction and overcoming resistance. , 1992, Cancer research.

[17]  N. Tsuji,et al.  Endogenous tumor necrosis factor functions as a resistant factor against hyperthermic cytotoxicity. , 1992, Cancer research.

[18]  M. Jäättelä,et al.  Major heat shock protein hsp70 protects tumor cells from tumor necrosis factor cytotoxicity. , 1992, The EMBO journal.

[19]  M. Krönke,et al.  Human 55-kDa receptor for tumor necrosis factor coupled to signal transduction cascades. , 1992, The Journal of biological chemistry.

[20]  N. Fan,et al.  The p70 tumor necrosis factor receptor mediates cytotoxicity , 1992, Cell.

[21]  D. Wallach,et al.  Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor. , 1992, The EMBO journal.

[22]  L. Tartaglia,et al.  The two different receptors for tumor necrosis factor mediate distinct cellular responses. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[23]  J. Norton,et al.  Pentoxifylline suppression of tumor necrosis factor gene transcription. , 1991, Surgery.

[24]  E. Schwartz,et al.  Regulation of c-myc expression by granulocyte-macrophage colony-stimulating factor in human leukemia cells. , 1991, Blood.

[25]  Y. Niitsu,et al.  Expression of endogenous tumor necrosis factor as a protective protein against the cytotoxicity of exogenous tumor necrosis factor. , 1990, Cancer research.

[26]  D. Goeddel,et al.  Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism , 1988, Science.

[27]  P. Scheurich,et al.  Tumor necrosis factor-induced changes of gene expression in U937 cells. Differentiation-dependent plasticity of the responsive state. , 1988, Journal of immunology.

[28]  C. Ware,et al.  Resistance to the cytolytic action of lymphotoxin and tumor necrosis factor coincides with the presence of gap junctions uniting target cells. , 1987, Journal of immunology.

[29]  B. Aggarwal,et al.  Induction of receptors for tumor necrosis factor-alpha by interferons is not a major mechanism for their synergistic cytotoxic response. , 1987, The Journal of biological chemistry.

[30]  R. Yamamoto,et al.  A high molecular weight component of the human tumor necrosis factor receptor is associated with cytotoxicity. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[31]  J. Giorgi,et al.  Sensitive method for measuring apoptosis and cell surface phenotype in human thymocytes by flow cytometry. , 1994, Cytometry.

[32]  W. Fiers,et al.  Tumour-necrosis-factor-mediated cytotoxicity is correlated with phospholipase-A2 activity, but not with arachidonic acid release per se. , 1991, European journal of biochemistry.