Distribution of 14C-ochratoxin A and 14C-ochratoxin B in rats: a comparison based on whole-body autoradiography.

The distribution patterns of ochratoxin A and its nontoxic dechloro-analogue ochratoxin B were studied in rats using whole-body autoradiography. No prominent difference in distribution patterns was found that could explain why the rat is the animal most susceptible to ochratoxin A-induced renal cancer or why ochratoxin B is less toxic than ochratoxin A.