Synthesis of 2-aminochromene derivatives catalyzed by KF/Al2O3

A series of 2-aminochromene derivatives including 2-amino-benzo[h] chromene, 2-amino-benzo [f] chromene and 2-aminopyrano [3, 2-h] quinolin derivatives was synthesized from arylaldehyde, malononitrile or ethyl cyanoacetate and 1-naphthol or 2-naphthol or 8-hydroxyquinoline in refluxing ethyl alcohol catalyzed by KF-Al2O3. The structures were confirmed by X-ray analysis.